Objective To explore the effects of improved suction syringe used during transporting patients on suction. Methods A total of 50 patients with oral tracheal intubation mechanical ventilation were selected in Emergency Room of the First Affiliated Hospital of Wenzhou Medical University from January to September 2015, patients were divided into experimental group and control group by the random number table, 25 cases in each group. Patients in experimental group were treated with suction with the improved suction syringe. Otherwise, patients in control group accepted suction with wall-mounting type aspirator. We compared the effects of suction and the rate of mucosa injury in two groups. Results There were no statistically significant differences in effects of suction and the rate of mucosa injury between the two groups (P> 0.05). Conclusions The improved suction syringe can achieve the same effects of suction with wall-mounting type aspirator and will not increase the rate of mucosa injury. It can be used in patients with artificial airway during clinical transportation.