No abstract available.
Humans

No abstract available.
Humans ; Somatoform Disorders*

The perchloric acid soluble, heat stable, and ethanol insoluble antigen of M. tuberculosis (TB-PBE) was prepared, and antigenicity of this antigen was studied in vivo and in vitro. TB-PBE showed a single band of 60 kDa by SDS-PAGE. Sera from the patients with active pulmonary tuberculosis did not react with this antigen by ELISA. A delayed hypersensitivity skin reaction was induced with this antigen and was correlated with the reaction with PPD. Skin biopsy was performed in this skin lesion induced by TB-PBE and stained by H-E and immunohistochemical methods. TB-PBE induced an inflammatory lesion similar to a lesion induced by PPD. Blastogenic activity of the peripheral blood mononuclear cells stimulated by TB-PBE increased, and showed a peak reaction at 7 days after stimulation. The blastogenic activity changed in a dose-dependent manner. After stimulation with TB-PBE, mononuclear cells were analyzed by FACS. DR+ T cells and CD4/CD8 ratio increased after stimulation by TB-PBE. These cells secreted IL-2, not IL-4 after stimulation with TB-PBE. In the immunofluorescence test, mouse antiserum against TB-PBE showed a positive reaction with M. tuberculosis and showed cross-reactivity with M. bovive and other atypical mycobacteria, but not with S. aureus. With these results, it is evident that TB-PBE is an antigen which can induce cell mediated immunity in vivo and in vitro.
Animal ; Antigens, Bacterial/immunology/*isolation & purification ; Cytokines/biosynthesis ; Electrophoresis, Polyacrylamide Gel ; Human ; Hypersensitivity, Delayed ; Lymphocyte Activation ; Mice ; Mice, Inbred BALB C ; Mycobacterium tuberculosis/*immunology ; Perchloric Acid ; Skin/pathology ; T-Lymphocytes/immunology

The perchloric acid soluble, heat stable, and ethanol insoluble antigen of M. tuberculosis (TB-PBE) was prepared, and antigenicity of this antigen was studied in vivo and in vitro. TB-PBE showed a single band of 60 kDa by SDS-PAGE. Sera from the patients with active pulmonary tuberculosis did not react with this antigen by ELISA. A delayed hypersensitivity skin reaction was induced with this antigen and was correlated with the reaction with PPD. Skin biopsy was performed in this skin lesion induced by TB-PBE and stained by H-E and immunohistochemical methods. TB-PBE induced an inflammatory lesion similar to a lesion induced by PPD. Blastogenic activity of the peripheral blood mononuclear cells stimulated by TB-PBE increased, and showed a peak reaction at 7 days after stimulation. The blastogenic activity changed in a dose-dependent manner. After stimulation with TB-PBE, mononuclear cells were analyzed by FACS. DR+ T cells and CD4/CD8 ratio increased after stimulation by TB-PBE. These cells secreted IL-2, not IL-4 after stimulation with TB-PBE. In the immunofluorescence test, mouse antiserum against TB-PBE showed a positive reaction with M. tuberculosis and showed cross-reactivity with M. bovive and other atypical mycobacteria, but not with S. aureus. With these results, it is evident that TB-PBE is an antigen which can induce cell mediated immunity in vivo and in vitro.
Animal ; Antigens, Bacterial/immunology/*isolation & purification ; Cytokines/biosynthesis ; Electrophoresis, Polyacrylamide Gel ; Human ; Hypersensitivity, Delayed ; Lymphocyte Activation ; Mice ; Mice, Inbred BALB C ; Mycobacterium tuberculosis/*immunology ; Perchloric Acid ; Skin/pathology ; T-Lymphocytes/immunology

We report a 37-year-old man who had a cutaneous marker of tuberous sclerosis with angiofibromas, periungal fibromas and who also showed bilateral verrucous hemangiomas on buttock. It is not known whether there is association between verrucous hemangioma and tuberous sclerosis, but there are some evidence suggest a more than chance association. We describe a case of bilateral verrucous hemangiomas combined with tuberous sclerosis.
Adult ; Angiofibroma ; Buttocks ; Fibroma ; Hemangioma* ; Humans ; Tuberous Sclerosis*

BACKGROUD: A lot of "Folk Remedies" on rheumatoid arthritis treatment prevail in Korea, but they have never been evaluated or investigated systemically. Therefore we studied folk remedies used in rheumatoid arthritis patients. METHODS: We delivered 12 questionnaires to 106 rheumatoid arthritis out -patients of family medicine, internal medicine, and orthopedics, located in Seoul and Kyungki area. These questionnaires addressed to demographic characteristics, duration of rheumatoid arthritis, current treatments, kind of folk remedies experienced, decision to choose folk remedies and its subjective effects, and volition to try new folk remedies. RESULTS: There were up to 27 kinds of folk remedies used by 77 people (72.8% of total). Lower education level was proved to be correlated with folk remedies experience. Most patients began their remedies introduced by relatives or close friends (83.1%) . Many Patients on folk remedies were skeptical about its effect, but they were still willing to try new folk medicine (80.6%). Many rheumatoid arthritis patients experienced folk remedies and were skeptical about its effects, but they were still willing to try new folk medicine. Therefore, education on folk remedies is needed.
Arthritis, Rheumatoid* ; Education ; Friends ; Humans ; Internal Medicine ; Korea ; Medicine, Traditional* ; Orthopedics ; Seoul ; Volition ; Surveys and Questionnaires

Mandibular arteriovenous malformations(AVM) are relatively rare and potentially life threatening lesions. Surgical treatment consists of wide resection of the mandible, which is difficult and potentially hazardous due to significant blood loss during surgery. Therefore, some authors advocate that transvenous embolization may be a safer and more effective method in the treatment of mandibular AVM. We report a treatment case of mandibular AVM in a 9-year-old-girl for episodes of spontaneous bleeding for 6 days using by selective transarterial embolization ,direct puncture embolization and microcoil embolization.
Arteriovenous Malformations* ; Hemorrhage ; Mandible ; Punctures

Microsporum canis is one of the zoophiles and pets(especially dogs and cats) play a role as a source of this organism. M. canis is most likely transmitted by contact of these animal hosts with humans. We report on 16 foreigners who are infected with M. canis transmitted from a show tiger. Fourteen of the patients had directly contact with a show tiger on occasion. Patients showed typical tinea corporis lesions on the extremities, and the tiger showed hairless patches on the abdomen. The culture and microscopic findings from patients' lesions revealed M. canis as the causative fungus.
Abdomen ; Animals ; Dogs ; Emigrants and Immigrants ; Extremities ; Fungi ; Humans ; Microsporum* ; Tigers* ; Tinea

After pelvic trauma, complications of urethral stricture and organic impotence may develop. Certain cases of these are combined with penile curvature, which treatment method of artificial erection alone is not suitable, because severe penile pain may occur during erection, Therefore proper surgical methods should be added for straightening the penile curvature. After pelvic trauma, complete urethral stricture and organic impotence with penile curvature developed in 3 patients who complained severe pain due to curvature during the intracavernosal injection test. To all, treatment of choice for complete urethral sticture was visual internal urethrotomy for prevention of further development of curvature, and for curvature, Nesbit's penile straightening operations were performed, one by one. All patients could well urinate and enjoy their sexual intercourse after intracavernosal injection of PGE1 or papaverine. We recommend visual internal urethrotomy and the Nesbit's operation as effective methods to treat the case of penile curvature combined with complete urethral stricture after pelvic trauma.
Alprostadil ; Coitus ; Erectile Dysfunction* ; Humans ; Male ; Papaverine ; Urethral Stricture*

Tumors in the retrorectal area are rare. Surgical approaches to retrorectal tumors include posterior, anterior, or combined approaches. We have encountered a case of a 56- year-old woman with a retrorectal tumor. She had a solid tumor, 3 cm in size, in the posterior midline rectum 7 cm above the anal verge. The tumor was successfully resected by using a posterior (transsacral) approach with a partial sacrectomy and was diagnosed as being a neurofibroma. There were no postoperative complications.
Female ; Humans ; Neurofibroma* ; Postoperative Complications ; Rectum