1.Brucella orchitis: A retrospective study of 69 cases.
National Journal of Andrology 2016;22(1):46-51
OBJECTIVETo investigate the epidemiological characteristics, clinical manifestations, diagnosis, and treatment of Brucella orchitis, so as to provide reliable evidence for the prevention and treatment of the disease.
METHODSWe conducted retrospective statistical analyses on the medical records of 48 outpatients and 21 inpatients with Brucella orchitis.
RESULTSBrucella orchitis was diagnosed in 6.67% of the male patients with brucellosis (69/1 034). The disease exhibited typical epidemiological features, with a higher incidence rate among those in frequent contact with sheep and elderly people, in the period from April to July, and in the areas with sheep husbandry. All the Brucella orchitis patients had such local symptoms as testicular pain and swelling, more frequently involving both testes, and other most common symptoms included fever, chills, sweating, and painful joints. Based on IIEF-5, 45 of the patients suffered from severe erectile dysfunction, with their reproductive function temporarily affected in the course of the disease. Misdiagnosis easily occurred in the early stage of the disease. Therapeutic options mainly included doxycycline hydrochloride and rifampicin, administered orally or intravenously, which could effect a cure, though relapse might occur in some cases.
CONCLUSIONBru- cella orchitis has distinct epidemiological characteristics, with clinical manifestations of testicular pain and swelling. Though a transient disease, it affects the reproductive function of the patient before cured. It can be treated by combined oral and intravenous medication, with painkillers or ice bags for testicular pain and swelling.
Animals ; Brucella ; pathogenicity ; Brucellosis ; complications ; diagnosis ; therapy ; Humans ; Male ; Orchitis ; diagnosis ; microbiology ; therapy ; Retrospective Studies ; Sheep
2.Acute Lymphoblastic Leukemia Associated with Brucellosis in Two Patients with Fever and Pancytopenia.
Bulent ESER ; Fevzi ALTUNTAS ; Isin SOYUER ; Ozlem ER ; Ozlem CANOZ ; Hasan Senol COSKUN ; Mustafa CETIN ; Ali UNAL
Yonsei Medical Journal 2006;47(5):741-744
Brucellosis is a disease involving the lymphoproliferative system, which may lead to changes in the hematological parameters; however, pancytopenia is a rare finding. However, malignant diseases in association with brucellosis are rarely the cause of pancytopenia. Herein, two cases with fever and pancytopenia, diagnosed as simultaneous acute lymphoblastic leukemia and brucellosis are presented. Anti-leukemic therapy and brucellosis treatment were administered simultaneously, and normal blood parameters obtained. The first patient is in complete remission; the other recovered from the brucellosis, but later died due to a leukemic relapse.
Pancytopenia/diagnosis/*etiology/therapy
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Leukemia, Lymphocytic, Acute/*complications/pathology/therapy
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Humans
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Fever
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Female
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Brucellosis/*complications/diagnosis/therapy
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Adult
3.Deep vein thrombosis associated with acute brucellosis: a case report and review of the literature.
Makram KOUBAA ; Makram FRIGUI ; Yousra CHERIF ; Moez JALLOULI ; Neila KADDOUR ; Mounir BEN JEMAA ; Zouheir BAHLOUL
The Korean Journal of Internal Medicine 2013;28(5):628-630
No abstract available.
Acute Disease
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Anti-Bacterial Agents/therapeutic use
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Anticoagulants/therapeutic use
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Brucellosis/*complications/diagnosis/drug therapy/microbiology/transmission
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Humans
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Male
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Middle Aged
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Thrombophlebitis/etiology
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Treatment Outcome
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Venous Thrombosis/diagnosis/drug therapy/*etiology