1.Radiologic Findings of Uncommon Breast Cancer.
Jae Woon KIM ; Jae Hong AN ; Mi Soo HWANG ; Jae Kyo LEE ; Woo Mok BYUN
Yeungnam University Journal of Medicine 1998;15(1):114-124
We analyzed the mammographic (n=21) findings (location, margin, shape, cluster microcalcifications, size, multiplicity) and ultrasonographic (n=12) findings (shape, border, internal echo, boundary echo, posterior echo, lateral echo, width/depth ratio) to evaluate specific radiologic findings of histopathologically proved uncommon breast cancer. The mammographic findings (n=21) are as follow; 1) single; 16, multiple; 5 2) margin (smooth; 13, irregular; 4, spiculated; 4) 3) shape (round and ovoid; 9, lobulated; 8, irregular; 4) 4) cluster microcalcifications (abscent; 20, present; 1) 5) size (1-3cm; 18, 3-5cm; 2, 5cm> ; 1) 6) location (UOQ; 13, UIQ; 4, LIQ; 3, LOQ; 1). The ultrasonographic findings (n=12) are as follow; 1) shape (round to oval; 5, lobulated; 5, irregular; 2) 2) border (smooth even; 9, rough uneven; 3) 3) internal echo (fine homogeneous; 5, coarse heterogeneous; 7) 4) boundary echo (regular fine; 4, irregular thick; 8) 5) posterior echo (enhanced; 11, no change; 1) 6) lateral echo (marked; 7, nonexistent; 5) 7) width/depth ratio (1.5> 1, 1.0-1.5; 7, 1.0< ; 4). Uncommon breast cancer show benign nature on mammogram, but malignant nature on ultrasonogram (especially boundary echo, internal echo, width/depth ratio)
Breast Neoplasms*
;
Breast*
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Radiography
;
Ultrasonography
2.Computed Tomographic Mammography in the Diagnosis of Breast Diseases.
Yonsei Medical Journal 1987;28(4):243-248
No abstract available.
Breast Diseases/radiography*
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Breast Neoplasms/radiography
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Female
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Human
;
Mammography/methods*
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Precancerous Conditions/radiography
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Tomography, X-Ray Computed*
3.Ductographic Findings of Breast Cancer.
Nariya CHO ; Woo Kyung MOON ; Sun Yang CHANG ; Joo Hee CHA ; Kyung Soo CHO ; Eun Kyung KIM ; Ki Keun OH
Korean Journal of Radiology 2005;6(1):31-36
Ductography has become the gold standard for the evaluation of patients exhibiting pathologic nipple discharges. In nine patients (age range, 29-67 years; median age, 51 years) with invasive (n=5) or intraductal (n=4) cancer, ductographic findings were recorded, then correlated with mammographic and sonographic findings. Common ductographic findings included complete ductal obstruction, multiple irregular filling defects in the nondilated peripheral ducts, ductal wall irregularities, periductal contrast extravasation, and ductal displacement. Faint microcalcifications or ill-defined masses, which were not opacified by contrast material, were often discovered adjacent to ductal abnormalities. Mammographically and sonographically occult diffusely spreading intraductal cancers often manifested as pathologic nipple discharge. In such cases, meticulous ductographic examinations and interpretations were crucial in order not to miss breast cancers.
Adult
;
Aged
;
Breast Neoplasms/*radiography/ultrasonography
;
Carcinoma, Ductal, Breast/*radiography/ultrasonography
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Female
;
Humans
;
Middle Aged
;
Nipples/*radiography/ultrasonography
;
Ultrasonography, Mammary
4.Pregnancy-Associated Breast Disease: Radiologic Features and Diagnostic Dilemmas.
Eun Ju SON ; Ki Keun OH ; Eun Kyung KIM
Yonsei Medical Journal 2006;47(1):34-42
In this paper, we evaluate the radiological features of pregnancy-associated breast lesions and discuss the difficulties in diagnosis by imaging. We selected patients who were diagnosed with pregnancy-associated breast lesions during the previous 5 years. All patients complained of palpable lesions in the breast and underwent ultrasonographic (US) examination, the first choice for examination of pregnancy-related breast lesions. Any suspicious lesions found by the US were recommended for a US-guided core biopsy, US-guided fine needle aspiration (FNA), or surgery. Various breast lesions were detected during pregnancy and lactation, including breast cancer, mastitis and abscesses, lactating adenoma, galactoceles, lobular hyperplasia, and fibroadenomas. The imaging features of pregnancy-associated breast lesions did not differ from the features of non-pregnancy-associated breast lesions; however, some pregnancy-associated benign lesions had suspicious sonographic features. A US-guided core biopsy was necessary for differentiating benign from malignant. In patients with breast cancer, the cancer was often advanced at the time of diagnosis. In conclusion, various pregnancy-related breast lesions were detected and the imaging of these lesions had variable findings. Breast ultrasound could be an excellent imaging modality for diagnosis and differentiation between benign and malignant lesions. However, when the imaging results are suspicious, a biopsy should be performed to obtain a pathologic diagnosis.
Ultrasonography, Mammary
;
Pregnancy Complications/diagnosis/*radiography/surgery
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Pregnancy
;
*Mammography
;
Humans
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Female
;
Breast Neoplasms/pathology/radiography/ultrasonography
;
Breast Diseases/pathology/*radiography/ultrasonography
;
Breast/pathology/surgery
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Biopsy
;
Adult
5.Carcinoma Mixed within Milk of Calcium in a Breast: a Case Report.
Ji Sung PARK ; Young Mi PARK ; Eun Kyung KIM ; Jin Hwa LEE ; Ok Hwa KIM ; Ji Hwa RYU
Korean Journal of Radiology 2008;9(Suppl):S7-S9
Milk of calcium located in the breast is typically a benign entity. However, carcinoma may incidentally arise adjacent to or even within milk of calcium. Consequently, the characteristics of all observed calcific particles should be carefully analyzed. In this study, we report a case of carcinoma presented as malignant microcalcifications mixed within milk of calcium in a breast.
Breast Neoplasms/*chemistry/radiography
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Calcium Carbonate/*analysis
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Carcinoma, Ductal/*chemistry/radiography
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Female
;
Humans
;
Mammography
;
Middle Aged
6.Radiologic and Clinical Features of Idiopathic Granulomatous Lobular Mastitis Mimicking Advanced Breast Cancer.
Jei Hee LEE ; Ki Keun OH ; Eun Kyung KIM ; Kyu Sung KWACK ; Woo Hee JUNG ; Han Kyung LEE
Yonsei Medical Journal 2006;47(1):78-84
Idiopathic granulomatous lobular mastitis (IGLM), also known as idiopathic granulomatous mastitis, is a rare chronic inflammatory lesion of the breast that can clinically and radiographically mimic breast carcinoma. The aim of this study was to describe the radiological imaging and clinical features of IGLM in order to better differentiate this disorder from breast cancer. We performed a retrospective analysis of the clinical and radiographic features of 11 women with a total of 12 IGLM lesions. The ages of these women ranged between 29 and 42 years, with a mean age of 34.8 years. Ten patients were examined by both mammography and sonography and one by sonography alone. The sites that were the most frequently involved were the peripheral (6/12), diffuse, (3/12), and subareolar (3/12) regions of the breast. The patient mammograms showed irregular ill-defined masses (7/11), diffuse increased densities (3/11), and one oval obscured mass. In addition, patient sonograms showed irregular tubular lesions (7/12) or lobulated masses with minimal parenchymal distortion (2/12), parenchymal distortion without definite mass lesions (2/12), and one oval mass. Subcutaneous fat obliteration (12/12) and skin thickening (11/12) were also observed in these patients. Contrary to previous reports, skin changes and subareolar involvement were not rare occurrences in IGLM. In conclusion, the sonographic features of IGLM show irregular or tubular hypoechoic masses with minimal parenchymal distortion. Both clinical information and the description of radiographic features of IGLM may aid in the differentiation between IGLM and breast cancer, however histological confirmation is still required for the proper diagnosis and treatment of the disorder.
Ultrasonography, Mammary
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Retrospective Studies
;
Mastitis/*radiography/ultrasonography
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Mammography
;
Humans
;
Female
;
Diagnosis, Differential
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Carcinoma/radiography/ultrasonography
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Breast Neoplasms/radiography/ultrasonography
;
Adult
7.Histological Analysis of Benign Breast Imaging Reporting and Data System Categories 4c and 5 Breast Lesions in Imaging Study.
Min Jung KIM ; Dokyung KIM ; Woohee JUNG ; Ja Seung KOO
Yonsei Medical Journal 2012;53(6):1203-1210
PURPOSE: The objective of this study was to analyze the histology of breast lesions categorized as Breast Imaging Reporting and Data System (BI-RADS) 4c or 5 breast lesions during the imaging evaluation, but diagnosed as benign during the histological evaluation. MATERIALS AND METHODS: We retrospectively reviewed 71 breast lesions categorized as BI-RADS 4c or 5 during imaging study, but diagnosed as benign upon histological evaluation. RESULTS: Breast lesions were classified into six groups upon histological analysis: intraductal papilloma (18 cases), inflammatory group (15 cases), fibroepithelial tumor (14 cases), clustered microcalcification (10 cases), minimal histological alteration (10 cases), and adenosis (4 cases). Sclerosis and architectural complexity were associated with most of the biopsies that were morphologically similar to malignancy. CONCLUSION: Among 71 cases categorized as 4c or 5 during the imaging study, but diagnosed as benign upon histological examination, intraductal papilloma was the most frequently identified histological lesion. These 71 cases exhibited histological characteristics of sclerosis and/or complex/complicated features that should be histologically differentiated from malignancy during evaluation.
Biopsy
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Breast Diseases/*diagnosis
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Breast Neoplasms/*diagnosis/*radiography
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Female
;
Humans
;
Retrospective Studies
8.Radiologic findings of metastatic signet ring cell carcinoma to the breast from stomach.
Jin Young KWAK ; Eun Kyung KIM ; Ki Keun OH
Yonsei Medical Journal 2000;41(5):669-672
Two Korean women (41 and 23-years of age) presented with painful breast enlargement and redness. The involved breast was confirmed as metastatic signet ring cell carcinoma. Although metastatic signet ring cell carcinoma of the breast shows similar clinical symptoms to inflammatory breast cancer, the difference between the two is that this malignancy showed no microcalcifications or mass on radiographic findings (mammograms and US). Therefore, after the confirmation of signet ring cell carcinoma of the breast has been made, metastatic signet ring cell carcinoma should be considered if there are no microcalcifications or masses evident on radiographic findings.
Adult
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Breast Neoplasms/secondary*
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Breast Neoplasms/radiography*
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Breast Neoplasms/pathology
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Carcinoma, Signet Ring Cell/secondary*
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Carcinoma, Signet Ring Cell/radiography*
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Carcinoma, Signet Ring Cell/radiography*
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Case Report
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Female
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Human
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Stomach Neoplasms/pathology*
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Tomography, X-Ray Computed
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Ultrasonography
9.Incidentally Detected Enhancing Breast Lesions on Chest Computed Tomography.
Wen Chiung LIN ; Hsian He HSU ; Chao Shiang LI ; Jyh Cherng YU ; Giu Cheng HSU ; Cheng Ping YU ; Tsun Hou CHANG ; Guo Shu HUANG
Korean Journal of Radiology 2011;12(1):44-51
OBJECTIVE: To evaluate the nature and imaging appearance of incidental enhancing breast lesions detected on a routine contrast-enhanced chest CT. MATERIALS AND METHODS: Twenty-three patients with incidental enhancing breast lesions on contrast-enhanced chest CT were retrospectively reviewed. The breast lesions were reviewed by unenhanced and enhanced CT, and evaluated by observing the shapes, margins, enhancement patterns and backgrounds of breast lesions. A histopathologic diagnosis or long-term follow-up served as reference standard. RESULTS: Sixteen (70%) patients had malignant breast lesions and seven (30%) had benign lesions. In 10 patients, the breast lesions were exclusively detected on contrast-enhanced CT. Using unenhanced CT, breast lesions with fibroglandular backgrounds were prone to be obscured (p < 0.001). Incidental primary breast cancer showed an non-significant trend of a higher percentage irregular margin (p = 0.056). All of the four incidental breast lesions with non-mass-like enhancement were proven to be malignant. CONCLUSION: Routine contrast-enhanced chest CT can reveal sufficient details to allow for the detection of unsuspected breast lesions, in which some cases may be proven as malignant. An irregular margin of incidental enhancing breast lesion can be considered a suggestive sign of malignancy.
Aged
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Breast Diseases/radiography
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Breast Neoplasms/*radiography/secondary
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*Contrast Media
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Female
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Humans
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*Incidental Findings
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Iohexol/*analogs & derivatives/diagnostic use
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Middle Aged
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*Radiography, Thoracic
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*Tomography, X-Ray Computed
10.The Role of Sonography in Patients with Breast Cancer Presenting as an Axillary Mass.
Sun Young PARK ; Eun Kyung KIM ; Ki Keun OH ; Kyong Sik LEE ; Byeong Woo PARK
Korean Journal of Radiology 2002;3(3):189-193
OBJECTIVE: To compare sonography and mammography in terms of their diagnostic value in breast cancer cases which initially presented as an axillary mass without a palpable mass or other clinical symptoms. MATERIALS AND METHODS: Seven patients with enlarged axillary lymph nodes who first presented with no evidence of palpable breast lesions and who underwent both mammography and sonography were enrolled in this study. In six of the seven, the presence of metastatic adenocarcinoma was confirmed preoperatively by axillary needle aspiration biopsy; in four, subsequent sonographicallyguided breast core biopsy performed after careful examination of the primary site indicated that primary breast cancer was present. In each case, the radiologic findings were evaluated by both breast sonography and mammography. RESULTS: Breast lesions were detected mammographically in four of seven cases (57%); in three of the four, the lesion presented as a mass, and in one as microcalcification. In three of these four detected cases, fatty or scattered fibroglandular breast parenchyma was present; in one, the parenchyma was dense. In the three cases in which lesions were not detected, mammography revealed the presence of heterogeneously dense parenchyma. Breast sonography showed that lesions were present in six of seven cases (86%); in the remaining patient, malignant microcalcification was detected at mammography. Final pathologic examination indicated that all breast lesions except one, which was a ductal carcinoma in situ, with microinvasion, were infiltrating ductal carcinomas whose size ranged from microscopic to greater than 3 cm. At the time of this study, all seven patients were alive and well, having been disease free for up to 61 months after surgery. CONCLUSION: In women with a palpable axillary mass confirmed as metastatic adenocarcinoma, breast sonography may be a valuable adjunct to mammography.
Adenocarcinoma/radiography/secondary/*ultrasonography
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Adult
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Axilla/*pathology
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Biopsy, Needle
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Breast/*pathology
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Breast Neoplasms/pathology/radiography/*ultrasonography
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Carcinoma, Infiltrating Duct/pathology/radiography/*ultrasonography
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Carcinoma, Intraductal, Noninfiltrating/pathology/radiography/*ultrasonography
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Female
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Human
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Lymph Nodes/radiography/*ultrasonography
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Mammography
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Middle Age
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Ultrasonography, Mammary