No abstract available.
Breast Neoplasms* ; Breast* ; Diagnosis*

No abstract available.
Breast Neoplasms* ; Breast* ; Diagnosis*

The first Korean Breast Cancer Treatment Consensus Conference Expert Panel reviewed and endorsed new evidence on aspects of local and regional therapies and diagnostic procedures that support the conservative application of results from recent clinical trials. This conference clarified the barriers that limit the application of recent clinical trial results, such as questions about level of evidence, differences between the setting of clinical trials and that of daily clinical practice, and medical necessities and environment. Detailed decisions recommended for the treatment and diagnosis, according to the from the consensus conference, are recorded including details of the votes. These recommendations differed in the degree of support for clinical consideration of disease extent and host factors, medical necessities, and environment.
Breast Neoplasms* ; Consensus* ; Diagnosis

A study was carried out to apply the IRMA to quantity the CA15-3 in the normal person and CA15-3 and CEA in the patients with the breast cancer. The clinical efficacy of CA15-3 and CEA were also evaluated. The subjects were normal people without tumor, chronic diseases, infection, inflamatory, hepatic diseases and the patients with the breast cancer who received the pathological anatomy and cytology.
Breast Neoplasms ; diagnosis ; Immunoradiometric Assay ; neoplasms ; breast

No abstract available.
Biopsy, Fine-Needle* ; Breast Neoplasms* ; Breast* ; Diagnosis*

The cystic hypersecretory duct carcinoma of the breast was first described in 1984 by Rosen and Scott and warrants separate discussion because of its unusual pathological features. It is morphologically distinguishable from juvenile (secretory) carcinoma and from mucinous (colloid) carcinoma or mucocele-like tumor. We present a case report of intraductal cystic hypersecretory carcinoma of the breast with hormone receptor and oncogene study. The histologic differential diagnosis, with an emphasis on benign lesions that may have a predominant cystic component, is also discussed.
Breast Neoplasms ; Breast* ; Diagnosis, Differential ; Mucins ; Oncogenes

PURPOSE: Family history of breast cancer can increase woman's risk of having the disease two to threefold. Patients with familial breast cancer affect the younger at diagnosis and have higher frequency of bilateral disease than those with sporadic cases. We evaluated the characteristics of familial breast cancer(FBC) patients including hereditary breast cancer(HBC) and compared those to sporadic breast cancer(SBC). MATERIALS & METHODS: Of the 885 patients operated on for breast cancer from January 1991 to December 1995 in Seoul National University hospital, 18 patients(2.0%) were classified as familial breast cancer and 5 patients as hereditary breast cancer by definition. RESULTS: The mean age of the patients was 45.7 years in FBC, 47.0 years in HBC and 46.8 years in SBC. The bilateral disease were more frequent in family history positive group(FBC; 22.2%, HBC; 60%) than SBC(1.5%) (p<0.01). In this series, there were no statistical differences in the age at onset, tumor location, histopathologic types and clinical stages amomg the different groups of the breast cancer, but bilateral cancer were seen more often in the familial history positive group than the other groups. CONCLUSION: As the frequency of familial and hereditary breast cancer was relatively low compared to that seen in other western countries, it would be necessary for the physician to inquire the family history of pateints with the breast cancer more carefully.
Breast Neoplasms* ; Breast* ; Diagnosis ; Humans ; Seoul

PURPOSE: To compare 3D ultrasound (3D-US) with 2D ultrasound (2D-US) in terms of their usefulness and limitations in the diagnosis of breast masses. MATERIALS AND METHODS: We obtained 2D and 3D US images of 37 breast lesions present in 20 cases of fibroadenoma, nine of cancer, and eight of fibrocystic disease proven in a total of 26 cases [fibroadenoma (n=13), breast cancer (n=9), fibrocystic disease (n=4)] by histologic examination, and by clinical evaluation and clinical evaluation with sonographic imaging in eleven. When comparing 3D and 2D-US images we had no prior information regarding detection rate according to the size of lesions, whether or not internal and boundary echo patterns could be interpreted, accurate differentiation between tumorous and non-tumorous lesions, or the accuracy with which benign and malignant tumors could be differentiated. RESULTS: For lesions of 1 cm or less in diameter the detection rate of 3D-US was lower than that of 2D-US, but for lesions over 1 cm there was no difference between the two modalities. In fibroadenoma and breast cancer, 3D-US was more useful than 2D-US for the evaluation of both internal and boundary echo, but with fibrocystic disease and in the diagnosis of tumor/non-tumor, there was no significant difference. In breast cancer, however, 3D-US more accurately determined malignancy, and in fibroadenoma, because of the pseudospicule revealed by 3D-US, this modality was less exact in determining benignancy. CONCLUSION: In the evaluation of internal and boundary echo in breast mass diagnosis, 3D-US was more useful than its 2D counterpart. For lesions of 1 cm or less in diameter, however, the detection rate of 3D-US was low, and since in some benign cases a pseudospicule was apparent, the possibiliy of confusion with malignancy arose. For these reasons, the usefulness of 3D-US was limited.
Breast Neoplasms ; Breast* ; Diagnosis* ; Fibroadenoma ; Ultrasonography

PURPOSE: We assessed the usefulness of resistive index(RI) on spectral analysis of Doppler sonography for differential diagnosis of benign and malignant breast lesions. MATERIALS AND METHODS: We retrospectively reviewed 29 benign and 22 malignant lesions of breast, which were examined preoperatively with color and duplex Doppler andwere confirmed by histopathologically after operation. We analyzed the average and distribution of RI in benignand malignant lesions. RESULTS: Although, there was no difference in the average values of RI in benign and malignant breast lesions, the distribution of RI was below 0.7 in eighteen cases (62%) of benign lesions, and above 0.7 in eighteen cases (82%) of malignant lesions. Thus, RI is valuable for differentiation between benignand malignant lesions of breast. CONCLUSIONS: Measurement of RI in breast disease using color and duplex Dopplerstudy is useful modality adjunct to the conventional ultrasonographic differentiation of benign and malignantlesions.
Breast Diseases ; Breast Neoplasms* ; Breast* ; Diagnosis ; Retrospective Studies

Breast Neoplasms ; diagnosis ; Female ; Humans ; Rhabdomyosarcoma ; diagnosis