1.Trilateral Retinoblastoma: A Case Report.
Eun Yoon CHO ; Yeon Lim SUH ; Hyung Jin SHIN
Journal of Korean Medical Science 2002;17(1):137-140
Trilateral retinoblastoma is a rare, but well recognized syndrome. These tumors usually occur in the pineal, parasellar, or suprasellar regions several years after successful management of ocular retinoblastomas without evidence of direct extension or distant metastasis. Here we report a case of trilateral retinoblastoma presenting initially with a sellar tumor and with concurrent unilateral retinoblastoma. The patient was a 5-month-old baby girl showing poor eye contact and nystagmus for several days. She had no family history of retinoblastoma. Brain MRI revealed a midline suprasellar tumor without evidence of cerebrospinal fluid seeding or extracranial metastasis. A pathologic diagnosis of retinoblastoma was made for her brain tumor, and a small, intraocular retinoblastoma was detected in the left eye by thorough examination of the fundus. If a retinoblastoma occurs in the midline of the brain, including the pineal and sellar regions, a careful screening to detect any additional retinal tumors should be performed. Moreover, since these tumors are often hereditary and harbor a worse prognosis, the diagnosis has implications for genetic counseling. This is the first report on a case of trilateral retinoblastoma in Korea presented with a sellar mass.
Brain/*pathology/radiography
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Brain Neoplasms/pathology/radiography/*secondary/surgery
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Female
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Humans
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Infant
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Retinal Neoplasms/*pathology/radiography/surgery
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Retinoblastoma/pathology/radiography/*secondary/surgery
2.Clinical Application of 7.0 T Magnetic Resonance Images in Gamma Knife Radiosurgery for a Patient with Brain Metastases.
Sun Ha PAEK ; Young Don SON ; Hyun Tai CHUNG ; Dong Gyu KIM ; Zang Hee CHO
Journal of Korean Medical Science 2011;26(6):839-843
In the study we assessed the distortion of 7.0 T magnetic resonance (MR) images in reference to 1.5 T MR images in the radiosurgery of metastatic brain tumors. Radiosurgery with Gamma Knife Perfexion(R) was performed for the treatment of a 54-yr-old female patient with multiple brain metastases by the co-registered images of the 7.0 T and 1.5 T magnetic resonance images (MRI). There was no significant discrepancy in the positions of anterior and posterior commissures as well as the locations of four metastatic brain tumors in the co-registered images between 7.0 T and 1.5 T MRI with better visualization of the anatomical details in 7.0 T MR images. This study demonstrates for the first time that 7.0 T MR images can be safely utilized in Perfexion(R) Gamma Knife radiosurgery for the treatment of metastatic brain tumors. Furthermore 7.0 T MR images provide better visualization of brain tumors without image distortion in comparison to 1.5 T MR images.
Adenocarcinoma/pathology/radiography
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Brain Neoplasms/pathology/secondary/*surgery
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Female
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Humans
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Lung Neoplasms/pathology/radiography
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*Magnetic Resonance Imaging
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Middle Aged
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*Radiosurgery
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Tomography, X-Ray Computed
3.A Case Report of Preoperative and Postoperative 7.0T Brain MRI in a Patient with a Small Cell Glioblastoma.
Sun Ha PAEK ; Jae Ha HWANG ; Dong Gyu KIM ; Seung Hong CHOI ; Chul Ho SOHN ; Sung Hye PARK ; Young Don SON ; Young Bo KIM ; Zang Hee CHO
Journal of Korean Medical Science 2014;29(7):1012-1017
A 45-yr-old female patient was admitted with one-month history of headache and progressive left hemiparesis. Brain magnetic resonance imaging (MRI) demonstrated a mass lesion in her right frontal lobe. Her brain tumor was confirmed as a small cell glioblastoma. Her follow-up brain MRI, taken at 8 months after her initial surgery demonstrated tumor recurrence in the right frontal lobe. Contrast-enhanced 7.0T brain magnetic resonance imaging (MRI) was safely performed before surgery and at the time of recurrence. Compared with 1.5T and 3.0T brain MRI, 7.0T MRI showed sharpened images of the brain tumor contexture with detailed anatomical information. The fused images of 7.0T and 1.5T brain MRI taken at the time of recurrence demonstrated no significant discrepancy in the positions of the anterior and the posterior commissures. It is suggested that 7.0T MRI can be safely utilized for better images of the maligant gliomas before and after surgery.
Brain Neoplasms/pathology/*radiography/surgery
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Female
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Frontal Lobe/radiography
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Glioblastoma/pathology/*radiography/surgery
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Humans
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In Situ Hybridization, Fluorescence
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*Magnetic Resonance Imaging
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Middle Aged
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Neoplasm Recurrence, Local
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Receptor, Epidermal Growth Factor/genetics
4.Profound hypothermia and cardiopulmonary bypass in the treatment of recurrent giant angioblastic meningioma case report.
Yong Gu CHUNG ; Ki Chan LEE ; In Sung LEE ; Nam Jun LEE
Journal of Korean Medical Science 1996;11(5):449-453
Hypothermia and cardiopulmonary bypass has rarely been used for difficult lesions of the brain such as giant aneurysms and hemangioblastoma of the brainstem. We report a case of huge recurrent angioblastic meningioma operated under the profound hypothermia and cardiopulmonary bypass. We reviewed the complications related to hypothermia and cardiopulmonary bypass for brain lesions.
Adult
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Brain Neoplasms/*surgery
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Cardiopulmonary Bypass/*methods
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Carotid Arteries/pathology
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Carotid Artery Diseases/therapy
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Case Report
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Cerebral Angiography
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Embolization, Therapeutic
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Fatal Outcome
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Female
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Human
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Hypothermia, Induced/*methods
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Lung/pathology/radiography
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Magnetic Resonance Imaging
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Meningioma/*surgery
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Neoplasms, Second Primary/*surgery
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Recurrence