The study aimed to establish the treatment strategy for some common tumors of the central nervous system. 43 patients with brain tumors and a patient with myeloma who admitted since 1995 were investigated retrospectively. It was found that invasive astroma and glioblastoma multiforme was commonest. There was not significant relationship between clinical features of brain tumor and type of cytology. Aggressiveness mainly related to the region and the volume of tumor. Located clinical signs tend to promote the patient seeking health care. Definitive diagnosis is based on histopathological findings with surgery or needle biopsy. Surgery is main option for treatment. Post operative radiotherapy was indicated for most of patients.
Brain Neoplasms ; diagnosis ; therapeutics

63 patients (male: 45, ages of 9-72) with the superior longitudinal paravenous sinus meningioma operated for removal of tumor and received the postoperative CT scanner and pathological anatomy for checking. Patients with meningioma, which invaded into the lumen of venous sinus but did not obstruct the vein, operated to nearly remove the tumor and excluded the invaded tumor into the venous lumen. Patients with meningioma that invaded into and obstructed the venous lumen received the second operation for legation of sinus and complete removal of the meningioma and obstructed venous sinus. These methods can exclude the disease for a long-time
Meningioma ; Brain Neoplasms ; diagnosis ; surgery

Magnetic resonance imaging (MRI) is an excellent exploring method for possibility of early and precise diagnosis, especially in the brain tumors and medullary lesions. The author presents special 9 cases of brain tumors and medullary lesions,which have been diagnosed by MRI, and operated at the section of Neurosurry Ha noi Saint- Paul Hospital in 1997
Magnetic Resonance Spectroscopy ; Brain Stem Neoplasms ; diagnosis

There has been a marked increase in the utility of aspiration cytology for pathologic diagnosis. It may be applied to any kinds of organs and substitutes surgical biopsy. Because of the high risk of complication and difficulties in localization, aspiration cytology in the central nervous system(CNS) has been used with less frequency compared to other sites. However, with the advent of sophisticated imaging instruments, aspiration cytology of lesions in the CNS is being used increasingly. Cytologic features of the CNS neoplasms were quite similar to those of histology except one spindle cell tumor. Reviewing various CNS neoplasms, it appears that cytology may be a useful diagnostic method.
Biopsy ; Brain Neoplasms ; Central Nervous System* ; Diagnosis

The authors report a case of angiographycally occult intracranial vascular malformation. The patient had huge calcified mass at left frontoparietal area. The preoperative diagnosis was a slowly growing benign tumor. The mass was very hard and so vascular malformation was not suspected even during the operation. Pathologic report revealed arteriovenous malformation.
Arteriovenous Malformations* ; Brain Neoplasms* ; Brain* ; Diagnosis ; Humans ; Vascular Malformations

The authors have studied six patients with histologically proven primary malignant lymphoma of the brain which is still a rare primary brain tumor. The clinical, radiological and pathological findings with results of the treatment are presented. All cases showed a good response to radiation therapy. Therefore, the early diagnosis by computerized tomography scan followed by biopsy or excision is considered to be very important for the BEST results in the treatment. Related reports are discussed briefly.
Biopsy ; Brain Neoplasms ; Brain* ; Drug Therapy ; Early Diagnosis ; Humans ; Lymphoma*

The authors analyzed and compared three prognostic factors of the intraparenchymal metastatic brain tumors, regardless of therapeutic modalities, to evaluate the value of time-interval between diagnosis of primary cancer and brain metastasis as a prognostic factor. Our of the 109 patients of metastatic brain tumor admitted to Kosin Medical College from 1984 to 1991, 93 patients were included in this retrospective study. The survival time of these patients was statistically evaluated according to each prognostic factor. The results were as follows. Patients with mild or no neurological deficits and patients with moderate neurological deficits showed longer survival than the patients with severe neurological deficits(P<0.001). The presence of systemic metastasis at the time of diagnosis also significantly shortened overall survival(P<0.0095). Primary-to-metastatic interval did not significantly affect overall survival(P<0.6164), but the patients with brain metastasis detected within 1 year after diagnosis of the primary cancer had a longer median survival than those detected after 1 year(P<0.001). We conclude that the primary-to-metastatic interval is not valuable as a prognostic factor for intraparenchymal metastatic brain tumor, and further prospective study tailored to each specific condition will be needed for more accurate evaluation of prognostic factors.
Brain Neoplasms ; Brain* ; Diagnosis ; Humans ; Neoplasm Metastasis* ; Prognosis* ; Retrospective Studies

Stereotaxic biopsy is an useful technique as an alternative to craniotomy for the tissue diagnosis of the intracranial tumors, especially such as deep seated tumor or malignant neoplasm in the dominant hemisphere. Such biopsy was more safe and lesser expensive than any other procedures and had high accuracy. For the purpose of more accuracy, the authors inserted small steel ball marker at the biopsy site and performed repeat C-T brain scanning immediately after the operation. We could confirm the marker in the tumor tissue on the C-T scans. The authors had experienced 4 cases of stereotaxic biopsy as follow; 2 cases of thalamic astrocytomas, 1 case of pineocytoma and 1 case of astrocytoma grade II in the dominant hemisphere. Neither mortality nor morbidity was noted.
Astrocytoma ; Biopsy* ; Brain Neoplasms* ; Brain* ; Craniotomy ; Diagnosis ; Mortality ; Pinealoma ; Steel

As more experience with computed tomography(C-T) is acquired, it is becoming apparent that differential diagnosis based on C-T appearances can be difficult. Many different pathologic processes can have similar enhancement patterns. We present 10 patients who underwent operation under the impression of brain tumor based on the C-T findings cannot be overemphasized. The clinician must be aware of the limitations and pitfalls associated with the computed tomography.
Brain Neoplasms* ; Brain* ; Diagnosis, Differential ; Humans ; Pathologic Processes

Fractionation dose and number have been known as radiation factor affecting the radiation complication and the effectiveness in radiotherapy for brain tumors. In this study hyperfractionation technique with 115cGy/fractioin 2 fractions daily 5days/wk, upto 5750-6900cGy to partial brain volume was compared with conventional fractionation technique with daily 200cGy/fraction 5 fraction/wk, upto 5400-6000cGy, in regarding to the effectiveness of hyperfractionated radiotherapy and eraly and later radiation reavtion. The survival period was longer in hyperfractionated irradiated group particularly if the tumors were located in the posterior portion of brain, however there was no singificant statistics due to small number of patients. Mean survival period for glioblastoma multiforme was 11.8 months in hyperfractionated group vs 8.7 months in conventional fractionated group and for high grade astrocytoma 36month in hyperfractionated group, but in conventional fractionated group all was died in 18 months. Acute radiation reaction occurred less frequently in hyperfractionated group, 15.8% vs 47.8% in conventional fractionated group(p<0.024). Alopeci was developed in 31.6% of the hyperfractionated group vs 82.6% of the conventional fractionated group(p<0.0031). One case of later radiation necrosis in cancer region was suspected in the hyperfractionated group but we has been in a dilemma for confirmatory diagnosis in present available diagnostic technique. The hyperfractionated irradiation technique was proven to be superior to conventional fractionated technique regarding the radiation reaction and the effectiveness of the treatment.
Astrocytoma ; Brain ; Brain Neoplasms ; Diagnosis ; Glioblastoma ; Glioma* ; Humans ; Necrosis ; Radiotherapy*