1.Intracranial squamous cell carcinoma developing in remnant of an epidermoid cyst: case report and literature review.
Li-ming GUAN ; Xi-xun QI ; Jing-rong ZHANG ; Ke XU ; Li-juan CUI ; Qiang ZHANG
Chinese Medical Journal 2004;117(12):1880-1883
Adult
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Brain Neoplasms
;
diagnosis
;
pathology
;
Carcinoma, Squamous Cell
;
diagnosis
;
pathology
;
Epidermal Cyst
;
pathology
;
Humans
;
Male
2.MRI features of intracranial primitive neuroectodermal tumors in adults: comparing with histopathological findings.
Haojun, SHI ; Xiangquan, KONG ; Haibo, XU ; Liying XU ; Dingxi, LIU
Journal of Huazhong University of Science and Technology (Medical Sciences) 2004;24(1):99-102
The MRI appearances of 7 adult patients with pathologically proven intracranial primitive neuroectodermal tumors (PNET) were retrospectively analyzed. The MRI features were compared with findings in pathology and surgery. In this group, the tumor masses were most commonly found in the semisphere of cerebrum and in the vermis of cerebellum. They were relatively large and 4 were in lobulated shape. All of them had well-defined margins. MR images showed the tumors to be mildly or obviously hypointense on T1-weighted images and hyperintense on T2-weighted images. Most masses had heterogeneous appearances with some cystic and necrotic areas. Intratumoral haemorrhage and focal calcification were occasionally seen. Mostly, there was no or only mild surrounding edema. Marked inhomogeneous contrast enhancement on MRI was seen in 6 cases except one. Two patients with multiple intracranial metastases were revealed on MR images. In this series, there was good correlation between MRI features and findings in pathology and surgery. These results showed that certain MRI features might suggest the diagnosis of intracranial PNET in adults. MRI is an effective technique to detect these tumors and is helpful to treatment planning and follow-up.
Brain Neoplasms/*diagnosis
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Brain Neoplasms/*pathology
;
*Magnetic Resonance Imaging
;
Neuroectodermal Tumors, Primitive/*diagnosis
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Neuroectodermal Tumors, Primitive/*pathology
;
Retrospective Studies
3.Importance of Contrast-Enhanced Fluid-Attenuated Inversion Recovery Magnetic Resonance Imaging in Various Intracranial Pathologic Conditions.
Eun Kyoung LEE ; Eun Ja LEE ; Sungwon KIM ; Yong Seok LEE
Korean Journal of Radiology 2016;17(1):127-141
Intracranial lesions may show contrast enhancement through various mechanisms that are closely associated with the disease process. The preferred magnetic resonance sequence in contrast imaging is T1-weighted imaging (T1WI) at most institutions. However, lesion enhancement is occasionally inconspicuous on T1WI. Although fluid-attenuated inversion recovery (FLAIR) sequences are commonly considered as T2-weighted imaging with dark cerebrospinal fluid, they also show mild T1-weighted contrast, which is responsible for the contrast enhancement. For several years, FLAIR imaging has been successfully incorporated as a routine sequence at our institution for contrast-enhanced (CE) brain imaging in detecting various intracranial diseases. In this pictorial essay, we describe and illustrate the diagnostic importance of CE-FLAIR imaging in various intracranial pathologic conditions.
Arachnoid Cysts/*diagnosis/pathology
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Brain/*pathology
;
Brain Neoplasms/*diagnosis/pathology
;
Contrast Media
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Humans
;
Magnetic Resonance Imaging/*methods
4.Primary intraventricular lymphoma with diffuse leptomeningeal spread at presentation.
Hasyma Abu HASSAN ; Norlisah M RAMLI ; Kartini RAHMAT
Annals of the Academy of Medicine, Singapore 2012;41(6):268-270
Aged
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Brain Neoplasms
;
diagnosis
;
pathology
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Central Nervous System Neoplasms
;
diagnosis
;
pathology
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Fatal Outcome
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Female
;
Humans
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Lymphoma
;
diagnosis
;
pathology
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Meningeal Neoplasms
;
diagnosis
;
secondary
5.Intracranial metastasis of malignant tumors: clinical characteristics and MR imaging features.
Chun-wu ZHOU ; Hong-mei ZHANG ; Han OUYANG
Chinese Journal of Oncology 2004;26(9):554-557
OBJECTIVETo study the clinical characteristics and MR imaging features of intracranial metastasis from malignant tumors.
METHODS1271 patients who had history of primary tumor and suspected of cranial metastasis had MRI on Philips Gyroscan T5-NT MR scanner. The sequences included pre-contrast T(1)WI, FLAIR, and postcontrast transversal, sagittal, and coronal T(1)WI. All of the clinical data and MRI features of the patients were recorded and analyzed.
RESULTSOf 547 patients with intracranial metastasis, 393 came from lung cancer (71.9%), 10% of 547 patients were found to have the presenting symptoms of cranial metastasis. 526 had parenchymal cerebral metastasis, and 21 only meningeal metastasis. Of these 526 patients found to have brain metastasis, 164 had single metastasis (31.2%), and 362 multiple (68.8%). Most of the cerebral metastatic lesions showed uniform or ring enhancement after intravenous injection of contrast medium, dura-arachnoid metastasis showed continuous and thick-curve enhancement at the cerebral convex, but not extending to the sulcus, while pia-dura metastasis displayed as thin and linear or nodular enhancement extending to the adjacent sulci.
CONCLUSIONThe most common primary lesion with metastasis to the brain were lung cancers, followed by breast and gastrointestinal cancers. By using gadolinium-DTPA enhanced MR imaging, many single and small cerebral metastasis could be found earlier.
Adult ; Aged ; Brain Neoplasms ; diagnosis ; secondary ; Breast Neoplasms ; pathology ; Female ; Gastrointestinal Neoplasms ; pathology ; Humans ; Lung Neoplasms ; pathology ; Magnetic Resonance Imaging ; Male ; Meningeal Neoplasms ; diagnosis ; secondary ; Middle Aged
6.Recent Advancement of the Molecular Diagnosis in Pediatric Brain Tumor
Jeong Mo BAE ; Jae Kyung WON ; Sung Hye PARK
Journal of Korean Neurosurgical Society 2018;61(3):376-385
Recent discoveries of brain tumor-related genes and fast advances in genomic testing technologies have led to the era of molecular diagnosis of brain tumor. Molecular profiling of brain tumor became the significant step in the diagnosis, the prediction of prognosis and the treatment of brain tumor. Because traditional molecular testing methods have limitations in time and cost for multiple gene tests, next-generation sequencing technologies are rapidly introduced into clinical practice. Targeted sequencing panels using these technologies have been developed for brain tumors. In this article, focused on pediatric brain tumor, key discoveries of brain tumor-related genes are reviewed and cancer panels used in the molecular profiling of brain tumor are discussed.
Brain Neoplasms
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Brain
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Diagnosis
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High-Throughput Nucleotide Sequencing
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Pathology, Molecular
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Pediatrics
;
Prognosis
7.Peripheral Ring Enhancement of Intracranial Lesions on CT Scan.
Journal of Korean Neurosurgical Society 1980;9(1):149-162
"Peripheral ring enhancement" of intracranial lesions in the CT examination is still being considered as a specific manifestation for abscess or a cyst tumor. The author analysed 33 cases with peripheral ring enhancement and concluded that although most of brain abscesses, metastatic brain tumors and cystic astrocytomas might demonstrate it, it was not specific for any diseases. To reach the correct diagnosis, it is necessary to collect and analyse the clinical features, laboratory data, and follow-up CT in addition to present CT findings. Examples of the various types of lesions that demonstrate peripheral ring enhancement are shown. It is suggested that various pathology could demonstrate "ring enhancement lesion", if CT scan were done at a fortuitous time. Some differential diagnostic suggestions are also made.
Abscess
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Astrocytoma
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Brain Abscess
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Brain Neoplasms
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Diagnosis
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Follow-Up Studies
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Pathology
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Tomography, X-Ray Computed*
9.Craniopharyngioma in the Temporal Lobe: A Case Report.
Chul Ho SOHN ; Seung Kug BAIK ; Sang Pyo KIM ; Il Man KIM ; Robert J SEVICK
Korean Journal of Radiology 2004;5(1):72-74
Herein, we report on an unusual case of craniopharyngioma arising in the temporal lobe with no prior history of surgery and with no connection to the craniopharyngeal duct. MR images showed a cystic tumor with a small solid portion. To the best of our knowledge, this is the first case of a craniopharyngioma occurring in the temporal lobe.
Adult
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Brain Neoplasms/diagnosis/*pathology/surgery
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Craniopharyngioma/diagnosis/*pathology/surgery
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Human
;
Magnetic Resonance Imaging
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Male
;
Temporal Lobe/*pathology/surgery
10.Dural metastasis of nasopharyngeal carcinoma: rare, but worth considering.
Chin-Lung KUO ; Donald Ming-Tak HO ; Ching-Yin HO
Singapore medical journal 2014;55(5):e82-4
Metastasis of nasopharyngeal carcinoma (NPC) to the dura, an extremely rare condition, can be symptomatically silent and mistaken for a benign entity radiographically. Missed diagnosis can lead to serious consequences or prove immediately fatal. We report a woman with dural metastasis of NPC that mimicked a meningioma on radiography. Craniectomy with tumour resection was performed due to rapid progression from the onset of symptoms to disability. The patient was still alive two years after surgery. This case emphasises the need to keep in mind the possibility of dural metastasis of NPC in patients with abnormal imaging features. This would not only avoid wrong and optimistic diagnosis, but also allow for appropriate treatment in a timely manner. To our knowledge, this is the first report of metastasis of NPC to the dura. We provide detailed information on the neoplastic lesion, which masqueraded as a benign entity and caused potentially fatal consequences.
Adult
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Brain Neoplasms
;
diagnosis
;
secondary
;
surgery
;
Carcinoma
;
Diagnosis, Differential
;
Disease Progression
;
Dura Mater
;
pathology
;
Female
;
Humans
;
Magnetic Resonance Imaging
;
Meningioma
;
diagnosis
;
pathology
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Nasopharyngeal Neoplasms
;
diagnosis
;
pathology
;
Neoplasm Metastasis