INTRODUCTION:Colonoscopy is the current standard method for evaluation of the colon. Diagnostic accuracy andtherapeutic safety of colonoscopy depends on the quality of the colonic cleansing or preparation.Thepreparation also would not cause any patient discomfort and would be inexpensive.GOAL:To compare two bowel preparation regimens for colonoscopy in terms of result of preparation.MATERIALS AND METHODS:A total 100 patients underwent colonoscopy were randomized to two bowel preparation regimens: A saltlaxative solution (n=50) oruse water enema (n=50). In group A, patients were consuming up to 5 L of saltlaxative solution at 8:00 an examination.Second groupB, patient received 6-9 L water enema the eveningbefore the colonoscopy, and the morning of the examination. Associated with the bowel preparationsuch as duration of examination, used volume of fluid, quality of bowel preparation was good (availabilitydetection of polyps greater than 5 mm), poor (inadequate cleansing).Data were entered into computer database using SPSS 20.0. The one simple test was used for analysisof categorical and ordinal variables. A Ð value of less than 0.05 was considered statistically significant.RESULTS:Using oral salt laxatives andwater enema preparation were decreased duration of examination, patientsatisfaction, successful cleaning of colon mucosa for both diasnostic and treatment procedure, decreasedtime for patient preparation.CONCLUSION:This randomized trial, salt laxative solution achieved better bowel preparation for colonoscopy than waterenema.