Objective To investigate prognosis of endometriosis and to determined correlative factors of pelvic pain associated with endometriosis after conservative surgery.Methods The clinical data in patients with pelvic pain related to endometriosis and underwent surgery treatment from January 2000 to September 2009 in Beijing Chaoyang Hospital were collected and sorted,then the patients were followed up.The data were analyzed by statistical software SPSS 13.0 for windows.Results A total of 332 patients with endometriomas were underwent conservative surgery,281 (84.6%,281/332) cases of them relieved pelvic pain.The univariate analysis showed that the effects were signficantly with age,Douglas pouch reconstruction,postoperative medical therapy,presacral neurectomy (PSN) and combined adenomyosis (all P<0.05).The multivariate analysis also showed that age(OR=0.946,P<0.01),Douglas pouch reconstruction (OR=0.208,P<0.01),postoperative medical therapy (OR=0.504,P<0.01),PSN (OR=0.121,P<0.05) and combined with adenomyosis (OR=2.528,P<0.01) were also the correlative factors to prognosis.Conclusion The protective factors for prognosis of pelvic pain associated with endometriosis included age,Douglas pouch reconstruction,postoperative medical therapy and PSN,while the risk factor was combined with uterine adenomyosis.