No abstract available.
Arteriovenous Malformations ; Embolization, Therapeutic ; Telangiectasia, Hereditary Hemorrhagic

Chemical leukoderma occurs due to the toxic effect of a specific chemical preceding allergic contact dermatitis. The mechanism is either destruction or inhibition of melanocytes by the offending substance. Clinicohistopathologically, no absolute criteria can differentiate chemical leukoderma from vitiligo. However, chemical leukoderma can be diagnosed clinically by a history of repeated exposure to a known or suspected depigmenting agent at the primary site. There is no agreed treatment guideline for chemical leukoderma. We report a healthy 51-year-old man who had multiple hypopigmented macules and patches on his face, neck, arms and legs after exposure to occupationally related chemicals. The lesions were recalcitrant to topical corticosteroids, but they showed much improvement after 3 cycles of systemic steroid pulse therapy. We suggest this therapy may be a good treatment option for chemical leukoderma.
Adrenal Cortex Hormones ; Arm ; Dermatitis, Allergic Contact ; Humans ; Leg ; Melanocytes ; Middle Aged ; Neck ; Occupations ; Vitiligo

Therapeutic options for infantile hemangioma are limited. The nonselective beta-adrenergic receptor antagonist propranolol is an effective therapy for infantile hemangiomas. However, systemic propranolol carries a risk of serious side effects, including bradycardia, hypoglycemia, arrhythmias, hypotension and bronchospasm. Recently, treatment of infantile hemangioma with topical timolol (nonselective beta-blocker similar to propranolol) has been reported. We treated successfully the perineal ulcerative hemangioma with topical timolol. We believe that timolol is a safe and effective topical agent and should be strongly considered as one of good therapeutic options for hemagnioma.
Arrhythmias, Cardiac ; Bradycardia ; Bronchial Spasm ; Hemangioma ; Hypoglycemia ; Hypotension ; Propranolol ; Timolol ; Ulcer

Therapeutic options for infantile hemangioma are limited. The nonselective beta-adrenergic receptor antagonist propranolol is an effective therapy for infantile hemangiomas. However, systemic propranolol carries a risk of serious side effects, including bradycardia, hypoglycemia, arrhythmias, hypotension and bronchospasm. Recently, treatment of infantile hemangioma with topical timolol (nonselective beta-blocker similar to propranolol) has been reported. We treated successfully the perineal ulcerative hemangioma with topical timolol. We believe that timolol is a safe and effective topical agent and should be strongly considered as one of good therapeutic options for hemagnioma.
Arrhythmias, Cardiac ; Bradycardia ; Bronchial Spasm ; Hemangioma ; Hypoglycemia ; Hypotension ; Propranolol ; Timolol ; Ulcer

No abstract available.
Dermatitis, Atopic

No abstract available.
Dermatitis, Atopic

Febrile ulceronecrotic pityriasis lichenoides et varioliformis acuta (PLEVA), or febrile ulcerative Mucha-Haberman disease (FUMHD) is very rare, but potentially lethal variants of PLEVA. This subtype is characterized by rapidly progressive ulceronecrotic lesions and systemic manifestations, such as high fever, gastrointestinal, neurological, cardiologic and pulmonary involvement, and rheumatologic manifestations. Several treatments with variable response have been challenged, such as systemic steroid, antibiotics, methotrexate, dapsone, cyclosporine and ultraviolet therapy. But there is no standard therapy for FUMHD to date. We report a 59-year-old woman with FUMHD, who recurred after discontinuation of systemic steroid, but successfully treated with oral cyclosporine.
Anti-Bacterial Agents ; Cyclosporine ; Dapsone ; Female ; Fever ; Humans ; Methotrexate ; Middle Aged ; Pityriasis ; Pityriasis Lichenoides ; Ulcer ; Ultraviolet Therapy

We report a case of tinea incognito in a 29-year-old man after applying the 0.03% tacrolimus ointment. He was known atopic dermatitis patient and has been treated with intermittent application of tacrolimus. For his facial pruritus 0.03% tacrolimus ointment was prescribed, and after one week he developed annularly grouped erythematous plaques and patches around the ointment-applied area. The KOH smear revealed multiple fungal hyphae. Dermatologists should be aware of the possibility of topical tacrolimus to be the causative agent for tinea incognito.
Dermatitis, Atopic ; Hyphae ; Pruritus ; Tacrolimus ; Tinea

No abstract available.
Eosinophilia ; Eosinophils ; Folliculitis ; Mucous Membrane ; Naproxen ; Skin Diseases, Vesiculobullous

No abstract available.
Eosinophilia ; Eosinophils ; Folliculitis ; Mucous Membrane ; Naproxen ; Skin Diseases, Vesiculobullous