The most common ocular finding of the idiopathic thrombocytopenic purpura(ITP) is superficial retinal hemorrhages in both eyes. But the descriptions of new vessel on the optic disc(NVD) associated with ITP are scarcely found in literatures. A 17-year-old girl who managed for ITP complained of visual distrubance of the right eye and floaters of the left eye. On fundoscopy the right eye was failed to examine due to thick vitreous hemorrhage and the left eye showed NVD and preretinal hemorrhage. After panretinal photocoagulation of the left eye, NVD was regressed.

Authors evaluated the retinal toxic reation of intravitreal injection with a regimens of 10 microgram of amphotericin B on both phakic and aphakic eyes of rabbits. In addition to the eye receiving single injection, the effects of repeating the same dose second and third time at interval of 1 week were examined by light microscopy after last injection. The results were as follows: 1. Even a single intravitreal injection with regimens of 10 microgram amphotericin B, vitreous opacities and posterior subcapsular lens opacities were observed ophthalmoscopically. 2. A single and repeated intravitreal injections with regimens of 10 microgram amphotericin B showed focal areas of retinal toxic reation. 3. Lens extraction did not modify the retinotoxic reation of intravitreally administrated amphotericin B. 4. Repetitive intravitreal injection of amphotericin B did not show increasing retinal toxic reation.
Amphotericin B* ; Cataract ; Intravitreal Injections* ; Microscopy ; Rabbits ; Retinaldehyde*

The authors have recently experienced a case of traumatic retinal angiopathy of 1.5 year old child which followed immediately a relatively minor injury on the head. 5 days after the accident, external examination of both eyes appeared normal and the fundi showed retinal edema, numerous superficial whitish exudates and flame-shaped retinal hemorrhages predominantly between the disc and macula. X-ray examinations of skull and chest revealed no evidence of fracture. Complete blood cell count, urinalysis, stool and cerebrospinal fluid findings were normal limits. Abnormal neurological signs were not detected. The area of exudates gradually absorbed over a period of one month but hemorrhages were still remained around the macula. The peripheral vision seemed to be improved but central fixation remained poor. 2 months later the fundi presented optic atrophy, attenuated arterial caliberation and cherry red spot at each macula.
Blood Cell Count ; Cerebrospinal Fluid ; Child ; Exudates and Transudates ; Head ; Hemorrhage ; Humans ; Optic Atrophy ; Papilledema ; Prunus ; Retinal Hemorrhage ; Retinaldehyde* ; Skull ; Thorax ; Urinalysis

Author presented the clinical evaluation for 34 patients of strabismus under the age of 12 years who were admitted to our clinic from September 1971 to August 1973. 1. The incidence of strabismus under 12 years of age was approximately 0.9% of the total out patients in our clinic, and 60.7% of these received surgical treatment. 2. Among them, 18 cases of exotropia, 15 cases of eostropia and 1 case of hypertropia were observed. 3. Average age at the time of operation was 5.9 years in esotropia and 7.1 years in exotropia. 4. Satisfactory result within 10 prism diopters of correction was obtained in 12 esotropias and 13 exotropias. 5. Improved fusional status was obtained in 9 esotropias and 14 exotropias.
Child* ; Esotropia ; Exotropia ; Humans ; Incidence ; Outpatients ; Strabismus*

Cytomegalovirus(CMV) retinitis is the most common opportunistic retinal in fection seen in patients with AIDS. It is almost always progressive and, if untreated, often leads to blindness. The authors report a case of unilateral CMV retinitis in 29-year-old female with AIDS, who complained of decreased vision in the left eye. Fundus examination showed areas of dense white retinal necrosis, scattered hemorrhages and perivascular sheathings. On urine culture CMV was also isolated. Treatment with ganciclovir was started and during the 2 mon ths of treatment, the retinitis was markedly resolved and visual acuity was improved to 0.7. CMV retinitis did not develop in the right eye.
Adult ; Blindness ; Cytomegalovirus Retinitis* ; Cytomegalovirus* ; Female ; Ganciclovir* ; Hemorrhage ; Humans ; Necrosis ; Retinaldehyde ; Retinitis ; Visual Acuity

Perfluorocarbon liquids are frequently used intraoperatively in repair of complicated retinal detachments. One complication of their use is prfluorocarbon liquids entering the subretinal space via a retinal break or an iatrogenic retmotomy since these liquids are much heavier than water, We evaluated the response to subretinal perfluorophenanthrene (VitreonR) on the rabbit retina ophthalmoscopically and microscopically. Twenty eight rabbit eyes underwent subretinal injection of 50-100 ml of perfluorophenanthrene via the vitreous space. The same volume of balanced salt solution was injected into control eyes. Eyes were monitored by indirect ophthalmoscopy and examined by light and electron microscopy. Progressive retinal detachments with newly formed retinal breaks in the inferior quadrants developed in 24 of 28 eyes. In the remaining 4 eyes, small retinal bleb, from 0.5 to 3DD size, occurred in inferior peripheral retina. The photoreceptor outer and inner segments were lost and receptor cell nuclei began to deplete within 1-3 days. In addition, marked vacuole formation in the retinal fiber layers as well as in inner and outer nuclear layers were seen. The photoreceptor outer and inner segments had a1most dlsappeared and the number of nuclei in irulei and outer nuclear layers was markedly decreased from 1 to 3 months. The control eyes reattached and healed spontaneously within 3-5 days. Our findings suggest that all subretinal perfluorophenanthrene should be carefully removed from the eyes at the end of the surgery.
Blister ; Cell Nucleus ; Microscopy, Electron ; Ophthalmoscopy ; Retina ; Retinal Detachment ; Retinal Perforations ; Retinaldehyde* ; Vacuoles

Perfluorocarbon liquids are frequently used intraoperatively in repair of complicated retinal detachments. One complication of their use is prfluorocarbon liquids entering the subretinal space via a retinal break or an iatrogenic retmotomy since these liquids are much heavier than water, We evaluated the response to subretinal perfluorophenanthrene (VitreonR) on the rabbit retina ophthalmoscopically and microscopically. Twenty eight rabbit eyes underwent subretinal injection of 50-100 ml of perfluorophenanthrene via the vitreous space. The same volume of balanced salt solution was injected into control eyes. Eyes were monitored by indirect ophthalmoscopy and examined by light and electron microscopy. Progressive retinal detachments with newly formed retinal breaks in the inferior quadrants developed in 24 of 28 eyes. In the remaining 4 eyes, small retinal bleb, from 0.5 to 3DD size, occurred in inferior peripheral retina. The photoreceptor outer and inner segments were lost and receptor cell nuclei began to deplete within 1-3 days. In addition, marked vacuole formation in the retinal fiber layers as well as in inner and outer nuclear layers were seen. The photoreceptor outer and inner segments had a1most dlsappeared and the number of nuclei in irulei and outer nuclear layers was markedly decreased from 1 to 3 months. The control eyes reattached and healed spontaneously within 3-5 days. Our findings suggest that all subretinal perfluorophenanthrene should be carefully removed from the eyes at the end of the surgery.
Blister ; Cell Nucleus ; Microscopy, Electron ; Ophthalmoscopy ; Retina ; Retinal Detachment ; Retinal Perforations ; Retinaldehyde* ; Vacuoles

Diode laser photocoagulation with laser ophthalmoscope has been shown to be effective and safe for treatment of threshold ROP. The purpose of this study are to deternine whether diode laser photocoagulation is really effective in reducing the likelihood of unfavorable regults in threshold stage. The eyes of neonates with birthweight of 2,500g or less, gestational age of 37 weeks or less, or exposure to increased ambient oxygen between May 1994 and October 1995 were examined, 21 eyes of threshold level of ROP and 2 eyes of prethreshold stage received diode laser photocoagulation. Nineteen(83%) of the 23 eyes that underwent laser photocoagulation had a favorable respons. Retinopathy of prematurity, however progressed to stage 4 in 2 eyes and stage 5 in 2 eyes. Two eyes in stage 4 achieved retinal reattachment after retinal buckling operation, but two eyes in stage 5 did not achieved retina1 reattachment. Regarding complications, one eye had retinal hemorihagic spot and one had presumed Bruch's membrane rupture. All infants had been followed up for minimum of 6 months. The results suggest that diode laser photocoagulation is an effective method in treatment of ROP, technically easier to administer without significant complication.
Bruch Membrane ; Gestational Age ; Humans ; Infant ; Infant, Newborn ; Lasers, Semiconductor* ; Light Coagulation* ; Ophthalmoscopes ; Oxygen ; Retinaldehyde ; Retinopathy of Prematurity* ; Rupture

Diode laser photocoagulation with laser ophthalmoscope has been shown to be effective and safe for treatment of threshold ROP. The purpose of this study are to deternine whether diode laser photocoagulation is really effective in reducing the likelihood of unfavorable regults in threshold stage. The eyes of neonates with birthweight of 2,500g or less, gestational age of 37 weeks or less, or exposure to increased ambient oxygen between May 1994 and October 1995 were examined, 21 eyes of threshold level of ROP and 2 eyes of prethreshold stage received diode laser photocoagulation. Nineteen(83%) of the 23 eyes that underwent laser photocoagulation had a favorable respons. Retinopathy of prematurity, however progressed to stage 4 in 2 eyes and stage 5 in 2 eyes. Two eyes in stage 4 achieved retinal reattachment after retinal buckling operation, but two eyes in stage 5 did not achieved retina1 reattachment. Regarding complications, one eye had retinal hemorihagic spot and one had presumed Bruch's membrane rupture. All infants had been followed up for minimum of 6 months. The results suggest that diode laser photocoagulation is an effective method in treatment of ROP, technically easier to administer without significant complication.
Bruch Membrane ; Gestational Age ; Humans ; Infant ; Infant, Newborn ; Lasers, Semiconductor* ; Light Coagulation* ; Ophthalmoscopes ; Oxygen ; Retinaldehyde ; Retinopathy of Prematurity* ; Rupture

The author experienced 3 cases of uveal effusion. The condition occurred bilaterally in a 48 year-old female and a 46 year-old male, and unilaterally in a 47 yearold male. Ophthalmoscopic examination revealed a nonrhegmatogenous bullous detachment of the retina. The subretinal fluid moved freely according to the head position in all cases. Fluorescein angiography showed several areas of subretinal leakage around the posterior pole in one case and none in the other 2 cases. Cerebrospinal fluid protein was elevated without pleocytosis in 2 cases. Analysis of subretinal fluid in 2 cases revealed a protein content more than 2 times that in plasma. Argon laser photocoagulation was applied to the areas of fluorescein leakage but was unsuccessful in causing lasting resolution of the detachment. In one case, partial thickness sclerectomies in lower nasal and temporal quadrants were made near the equator with drainage of subretinal fluid. The retina was reattached about a half year after operation.
Argon ; Cerebrospinal Fluid ; Drainage ; Female ; Fluorescein ; Fluorescein Angiography ; Head ; Humans ; Leukocytosis ; Light Coagulation ; Male ; Middle Aged ; Plasma ; Retina ; Subretinal Fluid