Congenital pulmonary lymphangiectasis is a rare cause of severe respiratory distress in the newborn period and most of these patient die, usually within the first 24 hours of life. The light microscopic characteristics of the lungs are a network of partly tubular, partly cystically enlarged lymph vessels within large areas of connective tissue and they have thin wall lined by endothelium. Also congenital pulmonary lymphangiectasis is closely associated with cardiovascular malformation, and most frequently occurs in the clinical setting of congenital heart disease with or without pulmonary venous obstruction(total anomalous venous return, atresia of large pulmonary veins) The authors describe three typical cases of congenital pulmonary lymphangiectasis.
Connective Tissue ; Endothelium ; Heart Defects, Congenital ; Humans ; Infant, Newborn ; Lung ; Lymphangiectasis* ; Lymphangioleiomyomatosis

Meningiomas is the usually slow-growing lesions that present either with vague nonlocalizing symptoms or with focal findings referable to compression of underlying brain. Cerebral infarction by meningiomas is unusual, especially as the initial presentation in a patient, and association with sudden death is extremely rare. The authors report the clinical, radiological and pathological findings in a case of cerebral infarction caused by thrombosis of the right middle cerebral artery following direct compression of a right temporal lobe meningioma. A 48-year-old woman developed a history of sudden neurologic deterioration, and shortly after she died. CT showed a large cerebral infarction in the right lobe. Autopsy revealed a right temporal lobe meningioma associated with right middle cerebral artery thrombosis, which made a large cerebral infarction.
Autopsy ; Brain ; Cerebral Infarction ; Death, Sudden ; Female ; Humans ; Infarction, Middle Cerebral Artery ; Meningioma* ; Middle Aged ; Middle Cerebral Artery ; Temporal Lobe ; Thrombosis

No abstract available.

No abstract available.
Head* ; Neck*

OBJECTIVE: To investigate the histologic features of the uterus and adnexae extirpated from gender identity disorder (GID) patients that received depot androgen injection. METHODS: We reviewed the histologic findings of the uterus and adnexae removed from sixteen GID patients, who had taken depot androgen injection for 5~168 months. RESULTS: Fourteen patients (87.5%) showed the atrophied epithelium of exocervix and all of 16 patients (100%) showed the atrophy of endometrium. Seven patients (43.7%) showed multiple cystic follicles in the ovarian cortex and 6 patients (37.5%), 3 patients (18.7%) showed corpus albicans and corpus luteum, respectively. CONCLUSIONS: Exogenous androgen induced atrophy of cervix and endometrium. This effect was more prominent in the endometrium. In addition, PCO-like histologic features were observed in the ovary.
Atrophy ; Cervix Uteri ; Corpus Luteum ; Endometrium ; Epithelium ; Female ; Gender Identity* ; Humans ; Ovary ; Uterus*

This statistical analysis of 4,709 legal autopsies performed in Korea in 2012 was conducted to obtain primary data about and related variables. The analysis revealed the following: 1. Of the total number of deaths, men accounted for and women, 26.8%. Evidently, the number of deaths among men was more than twice that among women. 2. With respect to mode of death, 54.8% were recorded as unnatural deaths, 39.2% were natural deaths, and 6.0% had unknown causes. Of the 2,581 unnatural deaths, 44.8% were accidental deaths; 27.2%, suicidal; 17.5%, homicidal; and 10.3%, undetermined. 3. Of the total number of unnatural deaths, 43.0% were trauma-related deaths, for which falling down was the leading cause, accounting for 33.5% cases. Asphyxiation was accounted for 17.2%, among which the predominant cause was hanging (55.3%). Moreover, 12.5% of deaths were due to drowning; 11.5%, poisoning; 11.2%, thermal injuries; 2.7%, complications in medical procedures; and 0.3%, electrocution, starvation, or neglect. 4. Among 1,847 natural deaths, heart diseases accounted for 50.2% and vascular diseases accounted for 16.7%. 5. There were 207 cases of deaths among children under the age of 10, of which 94 were unnatural and 49 were homicidal deaths. Of all cases, 9.2% had an unknown cause of death, and of these 67.6%, were putrefied or skeletonized bodies.
Autopsy* ; Cause of Death ; Child ; Drowning ; Female ; Heart Diseases ; Humans ; Korea* ; Male ; Poisoning ; Skeleton ; Starvation ; Vascular Diseases

Neurofibromatosis type1(von Recklinghausen's disease) is characterized by multiple skin tumors and abnormal cutaneous pigmentation(cafe au lait spots). Unlikely the solitary neurofibroma, those encountered in von Recklinghausen's disease may cause significant morbidity. The vasculopathy, although poorly recognized manifestation of von Recklinghausen's neurofibromatosis is a major cause of fatal cases. One of its most dramatic presentation is the spontaneous hemothorax. We report a case of Von Recklinghausen's disease with multiple neurofibromatosis accompanying intrathoracic hemorrhage due to vascular rupture, which is the first legal autopsy case in korea.
Autopsy ; Death, Sudden* ; Hemorrhage ; Hemothorax ; Humans ; Korea ; Neurofibroma ; Neurofibromatoses* ; Neurofibromatosis 1 ; Rupture ; Skin

Shotguns were developed as an alternative to single-missile rifle or handgun in order to enable gunner to spray a wide area with shot and thus kill birds and small animals too difficult to hit with single-missile weapons. As the popularity of shotguns grew, ammunition was developed for large game. The use of shotguns on humans has been markedly increasing in various manner of death. In forensic aspect, the shotgun wounds have characteristic findings due to their own characteristics and medical examiners may determine the range, distance, direction and kinds of gun. When the muzzle of the shotgun is placed tightly against the surface of the abdomen or thorax, the consequent wound of entrance will be single in number and circular in shape, and will have a diameter approximately equal to that of the bore of the weapon. However, when the wound is made over a site with underlying bone, especially in the scalp, the wound may have a different appearance, showing star shaped entrance due to tears from the sides of the wound and accompanying soot and burn effect. When the muzzle is held short to mid-range, considerable variation occurs in the appearance of the wound. We report two cases of shotgun wounds which showed typical findings of contact shots and distant shots.
Abdomen ; Animals ; Birds ; Burns ; Coroners and Medical Examiners ; Firearms ; Humans ; Scalp ; Soot ; Thorax ; Weapons ; Wounds and Injuries*

Shotguns were developed as an alternative to single-missile rifle or handgun in order to enable gunner to spray a wide area with shot and thus kill birds and small animals too difficult to hit with single-missile weapons. As the popularity of shotguns grew, ammunition was developed for large game. The use of shotguns on humans has been markedly increasing in various manner of death. In forensic aspect, the shotgun wounds have characteristic findings due to their own characteristics and medical examiners may determine the range, distance, direction and kinds of gun. When the muzzle of the shotgun is placed tightly against the surface of the abdomen or thorax, the consequent wound of entrance will be single in number and circular in shape, and will have a diameter approximately equal to that of the bore of the weapon. However, when the wound is made over a site with underlying bone, especially in the scalp, the wound may have a different appearance, showing star shaped entrance due to tears from the sides of the wound and accompanying soot and burn effect. When the muzzle is held short to mid-range, considerable variation occurs in the appearance of the wound. We report two cases of shotgun wounds which showed typical findings of contact shots and distant shots.
Abdomen ; Animals ; Birds ; Burns ; Coroners and Medical Examiners ; Firearms ; Humans ; Scalp ; Soot ; Thorax ; Weapons ; Wounds and Injuries*

We reviewed forensic autopsies and scene examinations performed at Central District of National Institute of Scientific Investigation, requested by every kinds of law enforecement agencies in Chung-cheong area of Korea during the year of 2002, and analysed the data of forensic autopsies and scene examinations according to the cause of death and the maner of death. The results are as follows ; 1. Scene examination on the spot was performed in 18 cases ; Among these cases, 17 cases were unnatural deaths and the most common cause of death was thermal injury. Autopy was performed in all 18 cases. 2. The total number of forensic autopsy were 590 cases (399 males and 191 females). The number of the thirties (155 cases) and the forties (118 cases) occupied almost half (46.3%) of all cases of autopsy. 3. Unnatural deaths were 378 cases (64.1%), natural 177 cases (30.0%), and the unknown 35 cases (5.9%). In 378 cases of unnatural deaths, suicide was 63 cases (16.7%), homicide 135 cases (35.7%), accident 94 cases (24.9%), and the undetermined 86 cases (22.7%). Homicide occupied 60.1% of trauma, 65.0% of blunt force injury excluding traffic and fall-down injury, and 91.4% of sharp force injury. The homicide rate in asphyxia was 61.0%, but it went up to 89.3% excluding hanging. It showed only 1 cases (2.0%) of homicide in poisoning. 4. In 378 cases of unnatural deaths, traumatic deaths were 167 cases(44.2%). Blunt trauma was 60 cases (35.9%) and the leading cause of death in traumatic death. Of remaining 211 cases of unnatural deaths, there were 61 cases (16.1%) of thermal injuries, 49 cases (13.0%) of poisonings, 46 cases (13.0%) of drowning, 41 cases (10.8%) of asphyxia, 9 cases (2.3%) of medical procedures, 4 cases (1.1%) of electrocution, and one case of neglect. 5. Among 177 natural deaths, cardiovascular diseases were 113 cases(63.8%) and the leading cause of death in natural deaths. 30 cases(16.9%) of diseases involving digestive system were followed. 6. Child deaths under the age of 10 were 45 cases. Among these cases, homicide were 24 cases(53.4%) and most of them occurred in the preschool period.
Asphyxia ; Autopsy* ; Cardiovascular Diseases ; Cause of Death ; Child ; Digestive System ; Drowning ; Homicide ; Humans ; Jurisprudence ; Korea* ; Male ; Poisoning ; Suicide