No abstract available.
Ophthalmology*

Here, we report 3 cases of mixed tumor of the lacrimal gland. The age of the patients were 43, 26 and 35 respectively. The two of these were male and one female. The most outstanding complaint was exopthalmos. A mass was palpated on the orbit and eye ball deviation in downward position was present in all cases. Pathologic findings were mixed tumor of the lacrimal gland with no evidence of malignancy. These tumors were well encapsulated and any evidence of involving bone and soft tissue was not found. Modified Kroenlein-Berke operation was performed and tumor mass was removed entirely with finger dissection in all cases. The vision was not improved but the cosmetic result was satisfactorr.
Female ; Fingers ; Humans ; Lacrimal Apparatus* ; Male ; Orbit

There were many instances in which glaucoma, esp. primary, combined with hearing disturbance. The etiology of these cases has not been known until now. We had 15 primary glaucoma patients for whom pure tone audiometry wa~ performed, and could find the hearing defect in high tone in 5 cases (1/3 among those patients). The audiometric curve was similar to that in the presbycusis, but severer in degree than that occured within the normal physiological aging process. The average age was 62.4 year in the group with the hearing defect, and 45.6 year in the group without the hearing defect. There were no relationship between the hearing defect and intraocular tension, visual field change, glaucomatous cupping, and duration of glaucoma. These results may support the opinion of the authors that the hearing disturbance in glaucomatous patients is related to the arterioscIerotic changes which aggrevate the presbycusis, and not related to glaucoma itself. On the otherhand, however, it is stilI impossible for us to rule out that the pleiotropic and multifactorial genetic factors may play as a common important role in the hearing disturbances and glaucoma. And further studies would be necessary for these problems.
Aging ; Audiometry ; Glaucoma* ; Hearing* ; Humans ; Presbycusis ; Visual Fields

The tension lowering effects of Diamox and other carbonic anhydrase inhibitors are well known and they are widely used against a various forms of glaucomas. This paper deals with the clinical experiences in normal and glaucomatous human eyes with Diamox-Sequels, kindly supplied by Lederle Laboratories and Yuhan Corp. MATERIALS AND METHODS: Normal healthy persons, 15 females and 20 males, were studied on their 45 eyes. Glaucomatous disease had been ruled out by careful examinations of intraocular pressure, visual fields and fundus. They had been also checked for the diurnal variations of intraocular pressure during the daytime. One capsule (500mg) of Diamox Sequels was given to each individual and the changes in the intraocular pressure were studied at various time intervals up to 53 hours after the administration. Tonometry was carried out by the Goldmann's applanation tonometer. The effects of Diamox Sequels on the glaucomatous eyes were studied in the same way. The glaucomatous eyes included 10 eyes of 7 chronic simple glaucoma patients, 5 eyes of 3 chronic narrow-angle glaucoma patients and 5 eyes of 5 secondary glaucoma subjects. They received one capsule of Diamox Sequels and the intraocular pressure was measured one or two times daily. The results of long-term treatment were also studied by daily administration of one capsule of Diamox Sequels, follow-up periods being from 3 to 19 days. No medication, oral or local, of antiglaucomatous drugs were allowed for at least 3 days prior to this study. The differences due to age, sex and type of glaucoma were not considered here. At the same time, the effects of a single 500mg of ordinary Diamox tablet were studied in normal ~md glaucomatous eyes. RESULTS: (1) Normal eyes. The intraocular pressure began to fall 1 hour after the administration. The tension gradually fell and the maximal reduction of tension occurred after 9.8 hours and the extent of maximal fall was 4.5mm Hg on the average, 29.4 % of the original intraocular pressure. The tension gradually rose and returned to the original level between 23~50 hours (average 43 hours). Side effects were noted in 4 cases, e.g., 11.4 %. (2) Glaucomatous eyes. The effects were noted within the first 1~2 hours and became maximal after 13 hours, the extent of the maximal fall 40.1 % of the original pressure, e.g., 16.2 mmHg. The original tension was restored after 30 hours. By long-term administration of Diamox Sequels, 8 eyes(40 %) showed excellent results, their intraocular pressure maintained below 21 mmHg. Sede-effects were noted in 3 cases(20.0 %). COMMENTS: The effects of Diamox Sequels and Diamox tablet on normal and glaucomatous subjects were summarized in table 1. As shown, Diamox Sequels has the longer duration of hypotensive actions and the time of maximal fall of intraocular pressure delayed considerably, as compared with Diamox tablet. In almost all cases, its action continued for more than 24 hours. In glaucomatous eyes, the time of maximal reduction of ocular tension was slightly later and the maintenance of low tension was slightly shorter than those in normal eyes. The extent of the maximal fall, however, was almost the same after administration of Diamox Sequels and Diamox. Side effects were encountered in 11~20% of cases by Diamox Sequels, and in 40-60% of cases by Diamox. This is one of the most striking advantages of Diamox Sequels over Diamox. Thus it is concluded that Diamox Sequels has the longer hypotensive actions and fewer side effects.
Acetazolamide* ; Carbonic Anhydrase Inhibitors ; Female ; Follow-Up Studies ; Glaucoma ; Glaucoma, Angle-Closure ; Glaucoma, Open-Angle ; Humans ; Intraocular Pressure ; Male ; Manometry ; Strikes, Employee ; Visual Fields

Twenty patients were operated on under the diagnosis of congenital nystagmus(CN). Of these, nineteen were motor CN and one was sensory CN. Head turning was toward the leftside in 13 patients(65.0%) and the rightside in 7(35.0%). Preoperatively, the degree of head turn ranged from 20 degrees to 45 degrees with a mean of 34.5 degrees. Primarily, modified Kestenbaum procedures were performed and, if necessary, 2nd and/or 3rd operations(Anderson's procedure, Goto's procedure) were performed additionally. The degrees of head turn after the 1st operation ranged from -5 degrees to 30 degrees with a mean of 11.5 degrees. On an average, 23.5 degrees was corrected by 14.8mm of operation on muscles(resection plus recession) for each eye. By these procedures, seventeen patients(85.0%) showed improvement or cure(75% after 1st operation and 10% after 2nd and/or 3rd operation).
Diagnosis ; Head ; Humans ; Nystagmus, Congenital*

Strabimus surgeries using n-butyl-2-cyanoacrylate and 6-0 vicryl suture material were performed in 16 albino rabbits. Both eyes of 16 rabbits were used. The superior and inferior rectus muscles were recessed and resected 5 mm. In 12 rabbits, n-butyl-2-cyanoacrylate was used and those rabbits were divided into 3 groups, each group(4 rabbits, 8 eyes) was sacrificed 1, 2, and 3 weeks after operation respectively. The eyes were enucle ated to examine the tensile strength and pathologic findings of the attached area. In 4 rabbits, 6-0 vicryl suture material was used a control group in this study. This group was sacrificed and examined 3 weeks following the operation. In the cyanoacrylate groups, there were statistically significant differences and a chrono-logically increasing thendency of tensile strength between groups. Between the cyanoacrylate and the suture material group at 3 weeks post operation, there was no statistically significant difference in the tensile strength. Pathologically, extraocular muscle bundles revealed patchy areas of interstitial inflammatory infiltration and fibrosis in the cyanoacrylate groups. Capillary telangiectasia and muscle fiber regeneration were commonly observed. The findings in specimens 3 weeks after operation revealed rather mild changes, suggesting healed lesions. In the suture material group, mild inflammatory reactions were found.
Capillaries ; Cyanoacrylates ; Enbucrilate ; Fibrosis ; Muscles ; Polyglactin 910 ; Rabbits ; Regeneration ; Strabismus* ; Sutures ; Telangiectasis ; Tensile Strength

To evaluate the results of bilateral recession in large angle exotropia we examined medical records of 73 patients who had exotropia larger than 35PD and underwent bilateral lateral rectus recession. The mean of follow-up period was 16months. Successful alignment, defined as a final alignment of orthophoria, esotropia less than 5PD or exotropia less than 10PD was achieved in 44 patients(60.3%). There were no differences in age, refractive error, preoperative angle of deviation, prevalence of amblyopia, the presence and concurrent correction of vertical or cyclodeviation, the development of diplopia and the duration of follow-up period between the successful alignment group and failure group. The esodeviation on postoperative one-day tended to ensure a more satisfactory result, but it was not statistically significant. There were no statistically significant differences in stereoacuity and postoperative angle of deviation among the different fusional ability groups. The stereoacuity and postoperative angle of deviation did not show a positive correlation. However, on the two separate examinations of the stereoacuity and fusional ability, the latter results showed improvement in both parameters. This result suggests that the correction of exodeviation may play a role in improving binocular visual function in patients with large angle exotropia.
Amblyopia ; Diplopia ; Esotropia ; Exotropia* ; Follow-Up Studies ; Humans ; Medical Records ; Prevalence ; Refractive Errors ; Telescopes

59 males and females were tested for the purpose of measuring the basic lacrimation under topical anesthesia of cornea and conjunctiva with 0.5% pontocaine using Toyo No.5 filter paper of 4.5 X 35mm in size. The total mean is 1.52mm/min and the means of male and female are 1.65mm/min and 1.37mm/min respectively. The mean of persons under 30 years of age is 1.68mm/min and that of over 30 years is 1.31mm/min. The means of male and female under 30 years of age are 2.12mm/min and 1.16mm/min and those of over 30 years are 1.01mm/min and 1.60mm/min respectively. The difference between means under 30 years and that of over 30 years in male is statistically significant but other differences are statistically not significant. The difference between auther's and other's values is, I suppose, derived partly from different filter paper used, and smallness of the number of person is another factor influenced.
Anesthesia ; Conjunctiva ; Cornea ; Female ; Humans* ; Male ; Tetracaine

Congenital ocular motor apraxia (COA), first described by Cogan in 1953, is a rare disorder which shows characteristic defect of horizontal voluntary saccades and head thrust. Until now, most cases have showed presumably congenital in origin, bilaterality, and tendency of various recovery with aging. But the causes and mechanisms of COA are not known. Occasionally, it combines with other neurologic abnormalities and the metabolic diseases such as Gaucher's disease which exhibits similar clinical characteristics of COA. We recently experienced a 3 years old girl who showed clinical features of unilateral congenital ocular motor apraxia.
Aging ; Apraxias* ; Child, Preschool ; Female ; Gaucher Disease ; Head ; Humans ; Metabolic Diseases ; Saccades

Congenital ocular motor apraxia (COA), first described by Cogan in 1953, is a rare disorder which shows characteristic defect of horizontal voluntary saccades and head thrust. Until now, most cases have showed presumably congenital in origin, bilaterality, and tendency of various recovery with aging. But the causes and mechanisms of COA are not known. Occasionally, it combines with other neurologic abnormalities and the metabolic diseases such as Gaucher's disease which exhibits similar clinical characteristics of COA. We recently experienced a 3 years old girl who showed clinical features of unilateral congenital ocular motor apraxia.
Aging ; Apraxias* ; Child, Preschool ; Female ; Gaucher Disease ; Head ; Humans ; Metabolic Diseases ; Saccades