Recent development of dignostic tools such as video-endoscopy, chromoscopy, magnifying endoscopy, and endoscopic ultrasonography has made it possible to do the accurate staging of colorectal cancer. Dysplasia confined to mucosa or upper one-third of submucosa of rectal wall can be treated with mucosal resection or local resection for cure. The involvement of perirectal lymph node by cancers can be confirmed by endoscopic ultrasonography-guided fine needle aspiration cytology (EUS-FNA). Positron emission tomography is useful for the detection of recurrent and metastatic tumor after surgical resection. Colonoscopy is cost-effective for the screening of cancer, however, But the virtual colonoscopy with MR or CT can play the role of colonoscopy without risk. Stool DNA test is a promising tool. In addition to traditional diagnostic tools such as colonoscopy, CT and pathology, emerging knowledge from molecular biology of cancer gives information on predicts the prognosis of colorectal cancer patients.
Biopsy, Fine-Needle ; Colonography, Computed Tomographic ; Colonoscopy ; Colorectal Neoplasms* ; Diagnosis* ; DNA ; Endoscopy ; Endosonography ; Humans ; Lymph Nodes ; Mass Screening ; Molecular Biology ; Mucous Membrane ; Pathology ; Positron-Emission Tomography ; Prognosis

No abstract available.
Diagnostic Errors*

This study was performed to investigate the retrievability of the cementation type implant abutments. The cements used in this study were Cavitec, Tembond and Zine Phosphate Cement. The types of surface conditioning were no treatment, 50 microne sandblasting, 250 microne sandblasting, fine diamond finishing point and coarse diamond point. The retention of cast crown was measured with Instron University Testing Machine(Instron Engineering Co., U.S.A.) The results were as follows: 1. The Maximium retention was obtained by the group of Z.P.C. cementation and Coarse diamond point surface conditioning. 2. Z.P.C. shows maximum retention, and reduced in orders Tembond, Cavitec, No cement. 3. The value of retention of surface condition was highest in coarse diamond point, lowest in no tretment. 4. The similar results were obtained between fine diamond point and 50 microne sandblasting, coarse diamond point and 250 microne sandblasting. 5. The were no direct corelation between mechanical retetnion and cementation retention.
Cementation* ; Crowns ; Diamond

A case of hereditary anhidrotic ectodermal dysplasia associated with atopic dermatitis in 16 month old male is reported. He has been suffered from multiple symptoms of anhidrosis, hypotrichosis, anodontia and atopic dermatitis. The skin showed pale, shiny, thin and dry and hairless on whole body except in the scalp. Without sweat gland and flattening of epidermis on skin biopey is compatible with an hereditary anhidrotic ectodermal dysplasia.
Anodontia ; Dermatitis, Atopic ; Ectodermal Dysplasia* ; Epidermis ; Humans ; Hypohidrosis ; Hypotrichosis ; Infant ; Male ; Scalp ; Skin ; Sweat Glands

No abstract available.
Humans ; Peptic Ulcer*

A case of familiar benign chronic pemphigus is reported. A 41 years old housewife has recurrent history of developing grouped vesicular eruptions with erythematous erosion on the intertrigenous area since 29 years of her age. The lesions were used to aggrevated in summer and improved in autumn. Familiar history revealed same disease of her grand mother, father, 44 year old elder sister and 39 year old younger sister. All of whom had similar clinical signs and symptoms. Routine physical and laboratoryfindings were within normal limits. The histopathological findings, from vesicular eruption of the lateral aspect of neck, showed multilocular suprabasal clefts with acantholsis, villi formation and hyperkeratosis. The lesions were-improved hy the local application of corticosteroidoid ointment only.
Adult ; Fathers ; Humans ; Mothers ; Neck ; Pemphigus, Benign Familial* ; Siblings

The 16 out of 19 cases with combined oral administration oral of Descrespet and Tetracycline hydrochloride were considerably more effective in treatment of severe acne than Tetracycline hydrochloride alone or placebo in this study. 10 cases of atopic dermatitis and 6 severe acne with side effect for tetracycline hydrochlorid, such as aMominal discomfortness, also treated with Descresapt: 7 cases of atopic dermatitis and 4 acne cleared definitely faster than in patient not given Descresept Conclusively, it is cnosidered that the Descresept is effective in the tretment of severe acne and atopic dermatitis.
Acne Vulgaris ; Administration, Oral ; Dermatitis, Atopic ; Humans ; Tetracycline

BACKGROUND: Eosinophils are suggested to play a deleterious role in the inflammatory disease of the respiratory mucosa by releasing granule substances such as major basic prorein and eosinophil cationic protein. To investigate the contribution of eosinophils in the pathogenesis of nasal polyps and the mechanism of their accumulation and activation, we observed the eosinophil inhllration and expression of endotjelial and epithelial cell adhesion molecules in the nasal polyp tissues. MATERIALS AND METHODS: Polyp and inferior turbinate mueosal specimens (polyp group) taken out of 20 patients and 10 inferior turbinate mucosa specimens of non-allergic and non-infectious controls (control group) were immunohistochemically stained using EG1, EG2, and mAb for the ICAM-1, VCAM-1 and E-seleetin. The number of EG1 (+) and EG2 (+) cells within lmm2 of tissue and the expression of ICAM-1, VCAM-1 and E-seleetin on the vessels (% of total vessel) and epithelial eelis (area x intensity) were compared among three groups. RESULTS:The inferior turbinate mucosae of nasal polyp patients .were infiltrated by signifieantly higher number of eosinophils (EG1:17, EG2:16/mm2) compared with those of controls (EGi:0, EG2:0/mm2) (p<0.05), and the polyp tissue revealed much more eosinophils (EG1: 213, EG2:154/mm2) than inferior turbinates of same patients and those of controls (p<0.001). ICAM-1 expression in the vessels was frequenly observed both in polyps and in the turbinate mucosae with significant difference (median:85% vs. 67%, p<0.05), and ICAM-1 expression in the epithelial ceils was significantly different between the polyp and turbinate groups (median:9 vs. 2.5, p<0. 01). VCAM-1 was moderately expressed on the vessels of both polyps and turbinate mucosac (median:37%, 14%, respectively) and their expressions were significantly different (p<0.01). E-selectin expression was moderate to low both in the polyps and in the turbinate mucosae (median:18%, 10% respectively) and their expressions were not significantly different (p>0.05). CONCLUSION: Most of the eosinophils infiltrated into nasal tissue as well as nasal polyps were activated forms and they were significantly increased in the nasal polyps compared to the inferior turbinate mueosae of the same patients and control subjects. Significantly increased expression of ICAM-1 and VCAM-1 on the vessels and increased epithelial ICAM-1 expression in the nasal polyps indicate that interactions of eosinophils with ICAM-1 and VCAM-1 participate in the pathogenesis of nasal polyps.
E-Selectin ; Eosinophil Cationic Protein ; Eosinophils* ; Epithelial Cells ; Humans ; Intercellular Adhesion Molecule-1 ; Mucous Membrane ; Nasal Polyps* ; Polyps ; Respiratory Mucosa ; Turbinates ; Vascular Cell Adhesion Molecule-1

The R-R interval analyzer was developed to measure the autonomic nervous system function using microcomputer. The system based on 8 bit microcomputer including bandpass filter, R-wave detector and clock generator in order to obtain the mean value, standard deviation, total time, CV value, maximum value and minimum value in the specific view point of R-R interval variation. The pattern of R-R interval change after resting, voluntary standing and deep breathing can be analyzed in normal subjects and diabetics with autonomic nervous dysfunction. The amplitude of the R-R interval variation showed sensitive pattern for normal subjects at resting, standing and deep breathing. On the contrary, the periodicities of amplitude for abnormal subjects with autonomic nervous dysfunction showed dull pattern. It was suggested that R-R interval analyzer is a good detection method for dysfunction of autonomic nervous system.
Autonomic Nervous System ; Methods ; Microcomputers* ; Periodicity ; Respiration

Congenital pulmonary lymphangiectasis is a rare cause of severe respiratory distress in the newborn period and most of these patient die, usually within the first 24 hours of life. The light microscopic characteristics of the lungs are a network of partly tubular, partly cystically enlarged lymph vessels within large areas of connective tissue and they have thin wall lined by endothelium. Also congenital pulmonary lymphangiectasis is closely associated with cardiovascular malformation, and most frequently occurs in the clinical setting of congenital heart disease with or without pulmonary venous obstruction(total anomalous venous return, atresia of large pulmonary veins) The authors describe three typical cases of congenital pulmonary lymphangiectasis.
Connective Tissue ; Endothelium ; Heart Defects, Congenital ; Humans ; Infant, Newborn ; Lung ; Lymphangiectasis* ; Lymphangioleiomyomatosis