No abstract available.
Doxorubicin* ; Drug Therapy* ; Small Cell Lung Carcinoma*

BACKGROUND: Tourniquet pain is probably mediated by C-fiber. The ability of fentanyl to interrupt this nociceptive conduction was studied by administering either fentanyl or saline intrathecally along with hyperbaric bupivacaine for spinal anesthesia. METHOD: The incidence of tourniquet pain was evaluated in 60 patients having orthopedic surgery of the lower extremities during spinal anesthesia by administering either 30 mcg fentanyl (group 2) or saline (group 1) along with 0.5% hyperbaric bupivacaine 10 mg. We measured the maximal sensory spread of analgesia to pinprick, the incidence of tourniquet pain, and the sensory anesthesia to pinprick at the onset of tourniquet pain. RESULTS: The average maximal sensory spread of analgesia was the same in both groups (T9). The incidence of tourniquet pain was significantly greater in group 1 (33%) than in group 2 (10%). The sensory levels of anesthesia at the onset of tourniquet pain were not different in two groups. CONCLUSIONS: Intrathecal fentanyl was effective against tourniquet pain for 2 hours of the orthopedic surgery of the lower extremities.
Analgesia ; Anesthesia ; Anesthesia, Spinal* ; Bupivacaine* ; Fentanyl* ; Humans ; Incidence ; Lower Extremity ; Orthopedics ; Tourniquets*

No abstract available.
Adult* ; Humans ; Lower Extremity*

No abstract available.

No abstract available.
Bezoars*

OBJECTIVE: To assess the reliability of triple marker screening test in midtrimester pregnancy for fetal Down syndrome. METHODS: From October 1, 1996 to May 31, 1998 at Nowon Eulji Hospital, 3700 Pregnant women underwent serum tiple marker screening for Down syndrome during 15-20weeks of gestational age. The results of serum triple marker screenig tests for Down syndrome and the outcomes of pregnancies were retrospectively assesed. RESULTS: Sixty seven of 3700 cases(1.81%) were positive in screening test, and 3633(98.18%) cases were negative. Among 67 cases of positive screening test, 1 case(1.49%) was diagnosed as Down syndrome. Among 3633 cases of negative screening test, 4 cases(0.1%) were diagnosed as chromosomal abnormalies postnatally. Two of these 4 cases of chromosomal abnormalies were Down syndrome. CONCLUSION: With this results, sensitivity of triple marker screeing test for Down syndrome is very low as 33.3%. In order to increase the sensitivity, some compensatory adjustment is required in triple marker screening test.
Down Syndrome* ; Equidae ; Female ; Gestational Age ; Humans ; Mass Screening* ; Pregnancy ; Pregnancy Outcome ; Pregnancy Trimester, Second* ; Pregnant Women ; Retrospective Studies

We evaluated Immunochromatographic assay kit to screen HBsAg in human serum. When the reference HBsAg was applyed to ICA, HA and EIA kits, the limit of detection for HBsAg were found out to be 4, 2 and 0.25 ng/ml respectively. But ICA kit required 5 minutes to read the result whereas HA and EIA kit more than one hour. The sensitivity was 97% (29 of 30 samples) and the specificity 100% (45 samples) compared with conventional EIA. The ICA kit needs no instrument or machine to perform the test contrary to the conventional methods. Therefore, this rapid and sensitive ICA kit can be used for HBsAg-screening, especially in the emergency room and in the scene of the accident.
Emergency Service, Hospital ; Hepatitis B Surface Antigens* ; Hepatitis B* ; Hepatitis* ; Humans ; Immunochromatography* ; Limit of Detection ; Sensitivity and Specificity

Traumatic dislocation of the testis is an unusual disorder and is characterized by an ectopically displaced testis as the result of closed injury. We report on 2 patients inguinal dislocation of the testis that was treated by orchiopexy, with brief of literatures.
Dislocations* ; Humans ; Orchiopexy ; Testis*

BACKGROUND: Intrathecal fentanyl has been known to have rapid analgesic effect for the first stage of labor, but pruritus usually occurs, and respiratory depression can happen. The addition of bupivacaine during intrathecal analgesia has been known to have synergistic action with intrathecal opioids. We observed the efficacy of the intrathecal injection of morphine, fentanyl, and bupivacaine on labor parturients. METHODS: 20 laboring patients were studied. Each patients received morphine 0.2 mg, bupivacaine 2.5 mg, and fentanyl 10 microgram intrathecally. Analgesia was assessed using visual analogue scale (VAS) score as the time elapsed from the drug administration to the delivery. Side effects such as nausea, vomiting, pruritus, urinary retention, respiratory depression, and hypotension were evaluated. RESULTS: The onset of analgesia was rapid (within 5 minutes) and VAS scores were significantly lower than pre-treatment value for 5 hours. The incidence of nausea or vomiting was 55% (11/20). Pruritus occurred 50% (10/20). The occurrence of urinary retention was 35% (7/20). Hypotension occurred 10% (2/20). No patient developed post dural-puncture headache, respiratory depression, fetal bradycardia, or motor weakness. More than 90% of the patients in this study said that they were satisfied with this analgesic procedure. CONCLUSIONS: Intrathecal injection of morphine 0.2 mg, fentanyl 10 microgram, and bupivacaine 2.5 mg provided rapid and effective analgesia in labor patients.
Analgesia* ; Analgesics, Opioid ; Bradycardia ; Bupivacaine* ; Female ; Fentanyl* ; Headache ; Humans ; Hypotension ; Incidence ; Injections, Spinal* ; Labor Pain ; Morphine* ; Nausea ; Pregnancy ; Pruritus ; Respiratory Insufficiency ; Urinary Retention ; Vomiting

Fracture of the occipital condyle is rare. We report the case of a patient with this fracture who presented with negative plain films and delayed hypoglossal nerve palsy. Diagnosis was estabilished with high resolution computed tomography. In a trauma patient with neck or occipital pain, with or without cranial nerve palsy, this fracture should be considered, even if a plain radiograph is negative.
Cranial Nerve Diseases ; Diagnosis ; Humans ; Hypoglossal Nerve Diseases* ; Hypoglossal Nerve* ; Neck