Rieger's syndrome is a rare autosomal dominant developmental anomaly characterized by ocular and systemic abnomalities. These disorders are typically bilateral and usually diagnosed at birth or in the childhood. The most common ocular defects are hypoplasia of the iris, a prominent Schwalbe's line with iris strands and corectopia. A large number of patients have glaucoma due to devel-opmental defects of the anterior chamber angle structure. The authors experienced a case of Rieger's syndrome which was found in 31-year-old female, who had characteristic ocular and other systemic abnormalities. Associated glaucoma was well controlled by filtering surgery.
Adult ; Anterior Chamber ; Atrophy ; Edema ; Female ; Filtering Surgery ; Frontal Lobe ; Glaucoma* ; Glioblastoma ; Humans ; Intracranial Pressure ; Iris ; Neurofibromatoses ; Optic Atrophy ; Optic Nerve ; Optic Nerve Diseases* ; Parturition ; Skin

PURPOSE: Ultrasonic scalers have been widely used for removing biofilm which is considered as major etiologic factor of periodontal disease. The purpose of this study was to evaluate the effect of working parameters of piezoeletric ultrasonic scaler with scaler tip (No. 1 tip) on casting gold alloy removal. METHODS:Type III dental casting gold alloy (Firmilay(R) , Jelenko Inc, CA, USA) was used as substitute for tooth substance. Piezoeletric ultrasonic scaler and No.1 scaler tip (P-Max(R) , Satelec, France) were selected. The selected working parameters were mode (P mode, S mode), power setting (2, 4, 8) and lateral force (0.5 N, 1.0 N, 2.0 N). The effect of working parameters was evaluated in terms of ablation depth, ablation width and ablation area. RESULTS: Mode influenced ablation depth and ablation area. Power also influenced ablation depth and ablation area. Especially, Power 2 and power 8 showed statistically significant difference. Lateral force had influence on ablation width, and 0.5 N resulted significant increase compared with 1.0 N and 2.0 N. Ablation depth was influenced by mode, power and lateral force and defect width was influenced by lateral force. Ablation area was influenced by mode and power. CONCLUSIONS: It can be concluded that the use of piezoelectric ultrasonic scaler with No. 1 scaler tip in S mode and high power may result in significant loss of tooth substance.
Alloys ; Biofilms ; Periodontal Diseases ; Tooth ; Ultrasonics

The urachus is a vestigial structure extending from the apex of the bladder to the umbilicus. Embryololigically, the urachus becomes obliterated during the third month of fetal life, but incomplete regression of the urachus results in anomalies. Urachal anomalies are very rare and present with varied appearances, one of which is vesicourachal diverticulum. Recently, we experienced a case of vesicourachal diverticulum complained of recurrent urinary tract infection in 13 month old male. Embryology, classification, clinical presentation, diagnostic modalities and treatment of urachal anomalies are reviewed.
Classification ; Diverticulum* ; Embryology ; Humans ; Infant ; Male ; Umbilicus ; Urachus ; Urinary Bladder ; Urinary Tract Infections

Pneumothorax and pulmomary edema can be produced as a complication during general anesthesia. The former which occurs during pressure ventilation is highly dangerous. It is characterized by a dramatic onset which is readily recongnized and demands immediate management. The latter may be developed after the upper airway obstruction has been relived due to the reduction of the intersitial hydrostatic pressure and increased capilary permeability. We experienced a case of pneumothorax and pulmonary edema that occurred after treatment for upper airway obstruction.
Airway Obstruction* ; Anesthesia, General ; Edema ; Hydrostatic Pressure ; Permeability ; Pneumothorax* ; Pulmonary Edema* ; Ventilation

A 32-year-old man was transferred to an intensive care unit due to respiratory difficulties with a 4-day history of progressive areflexic quadriparesis following acute hepatitis A. A nerve-conduction study revealed inexcitability of most nerves. The cerebrospinal fluid showed albuminocytologic dissociation, suggesting Guillain-Barre syndrome (GBS). The patient appeared brain dead on day 4, showing absent brainstem reflexes, respiratory failure, and fully dilated and fixed pupils. This case is an example of how GBS can evolve and simulate a brain-dead state from fulminant deafferentation following acute hepatitis A.
Adult ; Brain Death ; Brain Stem ; Cerebrospinal Fluid ; Guillain-Barre Syndrome* ; Hepatitis A* ; Hepatitis* ; Humans ; Intensive Care Units ; Pupil Disorders ; Quadriplegia ; Reflex ; Respiratory Insufficiency

Wegener's granulomatosis (WG) is characterized by necrotizing granulomatous vasculitis of small or medium sized vessels affecting the upper and lower respiratory tracts and kidney. It is well known that peripheral neuropathy is one of the leading manifestations of WG in western countries but there are rare cases of WG showing peripheral neuropathy in Korea. We report a patient with WG having peripheral neuropathy in his pathological and immunological findings.
Humans ; Kidney ; Korea ; Peripheral Nervous System Diseases* ; Respiratory System ; Vasculitis ; Wegener Granulomatosis*

Transient global amnesia(TGA) is a transient neurological syndrome, which occurs mostly once in life. Although the pathophysiology of TGA is not yet clear, there are well-known precipitating events such as emotional stress, physical exertion, sexual intercourse, painful experiences, and immersion in cold water. We report a 67-year-old man who developed recurrent amnestic episodes fulfilling the criteria for TGA. He had vascular risk factors and precipitating events. We suggest that the number of trigger events and vascular risk factors is associated with TGA recurrence.
Aged ; Amnesia, Transient Global ; Coitus ; Cold Temperature ; Humans ; Immersion ; Memory ; Physical Exertion ; Recurrence ; Risk Factors ; Stress, Psychological ; Water

The sense of taste is generally regarded as less important compare with vision and hearing. However, gustatory disorder considerably diminish the pleasures of life. The causes of taste disorder are various, and can occur during different pharmacologic treatment. We report a case of reversible ageusia induced by clopidogrel medication.
Ageusia* ; Hearing ; Humans ; Taste Disorders

PURPOSE: To evaluate the cerebral hemodynamic changes during interictal period in patients with epilepsy, we investigated changes in cerebral blood flow velocities by transcranial Doppler sonography (TCD). METHODS: Blood flow velocities and pulsatility indecies were measured in both anterior cerebral arteries, middle cerebral arteries, posterior cerebral arteries, internal carotid arteries, and basilar artery using TCD in 21 patients with epilepsy and 21 age and sex matched normal adults. We also evaluated the effects of seizure type, seizure frequency, EEG findings, and anticonvulsant medication on cerebral blood flow velocities. RESULTS: The blood flow velocities of cerebral arteries were decreased in patients, but the pulsatility indecies weren't different. Cerebral blood flow velocities were influenced by seizure type, EEG findings, or anticonvulsant medication. CONCLUSION: Our study demonstrates that cerebral blood flow velocities might be decreased during interictal period in patients with epilepsy, and suggests that TCD is an useful method for the investigation of the cerebral hemodynamic changes in epilepsy.
Adult ; Anterior Cerebral Artery ; Basilar Artery ; Blood Flow Velocity ; Carotid Artery, Internal ; Cerebral Arteries ; Electroencephalography ; Epilepsy* ; Hemodynamics ; Humans ; Middle Cerebral Artery ; Posterior Cerebral Artery ; Seizures ; Ultrasonography, Doppler, Transcranial

PURPOSE: The cerebral inflammatory reactions accompanied with epilepsy could play a role in intervening the possible changes of cerebral molecular structure during or after seizure. This study was intended to examine how much proinflammatory cytokines like interleukin (IL)-1beta, IL-6 and tumor necrosis factor (TNF)-alpha are expressed in animal model with seizures of mesial temporal lobe epilepsy and how their concentration in serum changes on the basis of phase, so that it could determine possible association between the development of epileptic seizures and the expression of cytokines. METHODS: Twenty Sprague-Dawley rats as experimental group had kainic acid (KA) administered intraperitonealy, and then, their behavioral patterns were monitored and recorded. In 4 and 24 hours after KA was administered, their bloods were taken respectively to determine the concentration of cytokines. The serum concentrations of IL-1beta, IL-6 and TNF-alpha were measured by means of enzyme linked immunosorbent assay (ELISA). The concentrations of IL-1beta, IL-6 and TNF-alpha were compared with controls, and also the phased variations of their concentration were determined. RESULTS: All rats in experimental group revealed various behaviors and seizure reactions. The serum concentrations of IL-1beta, IL-6 and TNF-alpha taken from rats in 4 and 24 hours after KA administration were more significantly increased than controls respectively (p<0.01). There was no significant variation in concentration of IL-1beta and IL-6 based on time phase, but there was significantly higher concentration of TNF-alpha in serum taken in 24 hours after KA administration than in 4 hours (p<0.05). CONCLUSION: These results show that seizure activity causes the elevation of proinflammatory cytokines and activates inflammatory reactions.
Animals ; Cytokines* ; Enzyme-Linked Immunosorbent Assay ; Epilepsy ; Epilepsy, Temporal Lobe ; Interleukin-1beta* ; Interleukin-6* ; Interleukins ; Kainic Acid ; Models, Animal ; Molecular Structure ; Rats* ; Rats, Sprague-Dawley ; Seizures* ; Tumor Necrosis Factor-alpha*