1.The Assessment of Worker's Health Status by SF-36.
Bong Suk CHA ; Sang Baek KOH ; Sei Jin CHANG ; Jong Ku PARK ; Myung Guen KANG
Korean Journal of Occupational and Environmental Medicine 1998;10(1):9-19
This study was conducted to understand health status by general characteristic, and to find out relationship between social support and worker's health status. Health status was measured using SF-36(Medical Outcome Study Short Form 36), a 36 item self administered Instrument. The finding of this study were as follow; Mean scores of health status by sex were higher in male. The younger worker reported good health on physical functioning and role limitation-physical than did the older worker, but the older worker reported good health on social functioning and mental health. Mean scores of health status were higher in high income and white worker. When the relationship between social support and health status, social functioning, role limitation-emotion, mental health, vitality, general health were significantly related. Therefore we reviewed the evidence that socio-economic condition are associated with health status in this study, and that the strength of the social support was a important to maintain health.
Humans
;
Male
;
Mental Health
;
Outcome Assessment (Health Care)
2.POEMS syndrome.
Moo Il KANG ; Kun Ho YOON ; Kwan Su HONG ; Bong Yun CHA ; Kwang Woo LEE ; Ho Young SON ; Sung Ku KANG
Journal of Korean Society of Endocrinology 1991;6(1):95-96
No abstract available.
POEMS Syndrome*
3.Relationship between magnesium and calcium to glucose stimulated insulin secretion in the perfused rat pancreas
Kun Ho YOON ; Soon Jip YOO ; Hyun Sik SON ; Moo Il KANG ; Kwan Soo HONG ; Bong Youn CHA ; Kwang Woo LEE ; Ho Young SON ; Sung Ku KANG
Journal of the Korean Diabetes Association 1991;15(1):63-71
4.diabetes insipidus during pregnancy.
Soon Jib YOO ; Je Young WOO ; Hyun Shik SON ; Bong Yeon YOON ; Moo Il KANG ; Kwan Soo HONG ; Bong Yeon CHA ; Ho Young SON ; Kwang Woo LEE ; Sung Ku KANG
Journal of Korean Society of Endocrinology 1992;7(4):384-390
No abstract available.
Diabetes Insipidus*
;
Pregnancy*
5.New Therapeutic Strategies against Helicobacter pylori.
Bong Ku KANG ; Sung Min PARK ; Byung Wook KIM
The Korean Journal of Gastroenterology 2014;63(3):146-150
The standard therapy for Helicobacter pylori infection in Korea is a triple-drug regimen consisting of a proton pump inhibitor with two antibiotics such as clarithromycin, amoxicillin, and metronidazole. However, as the eradication rate of this regimen has declined over the past decade, this prompted the formulation of new therapeutic regimens. New therapeutic strategies against H. pylori infection that had been tried all over the world include sequential therapy, concomitant therapy, and tailored therapy This article will review the basic concepts and the results of previous clinical trials on the aforementioned new therapeutic regiments.
Amoxicillin/pharmacology/therapeutic use
;
Anti-Bacterial Agents/pharmacology/*therapeutic use
;
Clarithromycin/pharmacology/therapeutic use
;
Disease Eradication/trends
;
Drug Therapy, Combination
;
Helicobacter Infections/*drug therapy
;
*Helicobacter pylori/drug effects
;
Humans
;
Nitroimidazoles/pharmacology/therapeutic use
;
Proton Pump Inhibitors/pharmacology/therapeutic use
6.The Impact of New Work Organizational System on Job Strain, and Psychosocial Distress.
Sang Baek KOH ; Sei Jin CHANG ; Byeong Hwan SUN ; Dong Muk KANG ; Mia SON ; Jong Ku PARK ; Bong Suk CHA
Korean Journal of Preventive Medicine 2003;36(1):71-76
OBJECTIVES: New organizational work systems, and their impact on the mental health of employees, are considered to beone of the most important topics in the area of industrial health. This study was conducted to compare job characteristics (job demand and decision latitude) levels, and psychosocial distress of workers in acompany introducing to new organizational work systems, to those of workers managed by traditional work systems. METHODS: A study sample of 627 shipbuilding workers (446the new work organizational system and 181the traditional system) were recruited for this study. A structured-questionnaire was used to assess general characteristics, job characteristics (work demand, decision latitude), and psychosocial distress. RESULTS: The decision latitude was not significantly higher in the new work system compared to the traditional system. However, the job demand was significantly higher in the new work system than in the traditional system. The psychosocial distress was higher within the new work system than the traditional system, but no significant relationships were found. The proportion of increased strain was significantly greater with the new system than the traditional system. CONCLUSION: These results suggest that increases in the decision latitude did not sufficiently compensate for higher job strain or increased work intensity. If the increase in the decision latitude was temporary, with the typical job demand remaining high, such work can be still be considered to have a job strain. Future research should consider psychosocial distress and fatigue as important problems caused by new work organizational systems, and should be performed to assess their impact through out industry.
Fatigue
;
Mental Health
;
Occupational Health
7.Helicobacter pylori Virulence Factors and Host Factors.
The Korean Journal of Helicobacter and Upper Gastrointestinal Research 2011;11(1):7-12
Helicobacter pylori (H. pylori) is one of the most common human infection world-wide. However, only a limited proportion of the infected population developed gastrointestinal diseases such as peptic ulcer disease, gastric adenocarcinoma, and mucosa-associated lymphoid tissue lymphoma. These various outcomes of H. pylori infection may result from bacterial virulence factors, host factors such as genetic diversities, and environmental influences. Bacterial factors such as cagA PAI, vacA, adhesin and outer membrane proteins, and peptidoglycans are known to be associated with specific gastrointestinal diseases such gastric adenocarcinoma. Various cytokines including interleukin (IL)-1beta, IL-10, and tumor necrosis factor-alpha, and host immune reaction to the bacteria are closely related to specific diseases such as gastric adenocarcinoma and duodenal ulcer. In this article, we reviewed each factors and their relevance to the disease outcome.
Adenocarcinoma
;
Bacteria
;
Cytokines
;
Duodenal Ulcer
;
Gastrointestinal Diseases
;
Genetic Variation
;
Helicobacter
;
Helicobacter pylori
;
Humans
;
Interleukin-10
;
Interleukins
;
Lymphoma, B-Cell, Marginal Zone
;
Membrane Proteins
;
Peptic Ulcer
;
Peptidoglycan
;
Stomach Diseases
;
Tumor Necrosis Factor-alpha
;
Virulence Factors
8.Reliability and Validity on Measurement Instrument for Health Status Assessment in Occupational Workers.
Sang Baek KOH ; Sei Jin CHANG ; Myung Guen KANG ; Bong Suk CHA ; Jong Ku PARK
Korean Journal of Preventive Medicine 1997;30(2):251-266
In order to test scaling assumption, and to assess the validity, reliability, and acceptability of the Short Form 36(SF-36) health survey questionnaire, we conducted a survey. Samples were 296 workers who had been employed in small sized companies. All scale passed for item internal consistency(100% sucess rate) and item discriminant validity(100% success rate). Reliability coefficients were ranged from a low of 0.51 to a high of 0.85. For 87.5% of the total workers, inconsistent responses were not observed. Only 3.0% of the total workers failed two or more checks. Factor analysis was performed using principal axis factor method and quartimax rotation. In this survey, the SF-36 retained available psychometric properties even when used in a generally healthy worker group. But further study with some consideration to develope health status measurement is expected ; first, the definition of health status should be rationalized. Second, the measurement of outcome is an important consideration in evaluations of quality of care. But ambiguities hinder understanding of this important topic. Third, internal consistency should be interpreted with caution as an indication reliability because it ignores potentially important sources of variation that can occur over time.
Axis, Cervical Vertebra
;
Health Surveys
;
Psychometrics
;
Surveys and Questionnaires
;
Reproducibility of Results*
9.Effect of Noise Exposure and Psychosocial Factors on Blood Pressure in Manufacturing Workers.
Bong Suk CHA ; Sang Baek KOH ; Sei Jin CHANG ; Jung Ku PARK ; Myung Guen KANG ; Sang Yul KOH
Korean Journal of Occupational and Environmental Medicine 1997;9(2):244-257
This study was conducted to assess the effects of noise exposure and psychosocial factor on blood pressure in manufacturing workers. The study subjects are 414 workers (243 males, 171 females) employed at the noisy department. The mean age of low exposed group (<85dB) was 34.65+/-9.53 years, and that of high exposed group (> or =85dB) was 36.37+/-11.15 years. The difference in mean age wart not significant. The mean and distribution of working duration, smoking status, drinking status were not significantly different between two groups. The mean systolic blood pressure of the low exposed groups was 120.01+/-12.06 mmHg, and that of high exposed group wart 126.27+/-13.84 mmHg. The mean diastolic blood pressure of the low exposed and the high exposed group were 77.18+/-10.83 mmHg, and 83.46+/-11.22 mmHg respectively. These differences of blood pressure were statistically significant(p<0.05). The workers in noisy department have significantly less work environmental satisfaction, higher job demand, and higher social support. The mean values of psychosocial distress were higher in the workers of the noisy department, but the difference was not statistically significant. This study was to speculate whether the work environmental satisfaction and social supports modify the association between the noise exposure level and the blood pressure. The results showed that work environmental satisfaction could not modify the association between the blood pressure and the noise exposure. Social support at work did not modify the association. Furthermore, we evaluated the high job strain from a combination of high job demand and low job control at work. Compared to the low strain group, the olds ratio of the high job strain group for hypertension in diastolic blood pressure were statistically significant, but not in systolic blood pressure. Hierarchical multiple regression analysis was used to determine whether the independent variables contributed to explaining the blood pressure. After controlling for possible confounders, we found that the noise exposure level was a correlate of the diastolic blood pressure. But no association between the noise exposure level and the systolic blood pressure. No significant result was found for psychosocial factor.
Blood Pressure*
;
Drinking
;
Humans
;
Hypertension
;
Male
;
Noise*
;
Psychology*
;
Smoke
;
Smoking
;
Warts
10.Association between Job Stress on Heart Rate Variability and Metabolic Syndrome in Shipyard Male Workers.
Myung Guen KANG ; Sang Baek KOH ; Bong Suk CHA ; Jong Ku PARK ; Jong Min WOO ; Sei Jin CHANG
Yonsei Medical Journal 2004;45(5):838-846
A growing body of literature has documented that job stress is associated with the development of cardiovascular disease. Nevertheless, the pathophysiological mechanism of this association remains unclear. The purpose of this study is to elucidate the relationship between job stress, heart rate variability, and metabolic syndrome. The study design was cross-sectional, and a total of 169 industrial workers were recruited. A structured-questionnaire was used to assess the general characteristics and job characteristics (work demand, decision latitude). Heart rate variability (HRV) was recorded using SA-2000 (medi-core), and was assessed by time-domain and by frequency-domain analyses. Time domain analysis was performed using SDNN (Standard Deviation of normal to normal interval), and spectral analysis using low-frequency (LF), high-frequency (HF), and total frequency power. Metabolic syndrome was defined on the basis of risk factors being clustered when three or more of the following cardiovascular risk factors were included in the fifth quintile: glucose, systolic blood pressure, high-density lipoprotein cholesterol (bottom quintile), triglyceride, and waist-hip ratio. The results showed that job characteristics were not associated with cardiovascular risk factors. Compared to the lower strain group (low strain+passive+active group), the high strain group had a less favorable cardiovascular risk profile with higher levels of blood pressure, glucose, homocysteine, and clotting factor, but the difference was not statistically significant. The SDNN of HRV was significantly lower in the high strain group than in the low strain group. The prevalence of metabolic syndrome in the lower strain group and high strain group was 13.2% and 23.8%, respectively. In the high strain group, the metabolic syndrome was significantly related to a decreased SDNN. However, we could not find a significant association in LF/HF ratio. This result suggests that decreased HRV found in the high-strain group are not a direct indicator of disease. However, it can induce cardiovascular abnormalities or dysfunctions related to the onset of heart disease among high risk groups.
Adult
;
Aged
;
*Heart Rate
;
Humans
;
Male
;
Metabolic Syndrome X/*physiopathology
;
Middle Aged
;
Occupational Diseases/*physiopathology
;
Research Support, Non-U.S. Gov't
;
Stress, Psychological/*physiopathology