A case of sporotrichosis, developed on left upper eyelid in 2 weeks after double eyelid operation, was presented. Eruptions were distributed along the operation site and similar to pyoderma or keloid. Painless subcutaneous nodule appeared near the lateral angle of eye in 8 months after onset. Sporotrichum schenckii was cultivated from the tissue fluid of the lesion. PAS positive spores were found extra-cellularly and in histiocytes and multi-nucleated giant cells.
Eyelids* ; Giant Cells ; Histiocytes ; Keloid ; Pyoderma ; Spores ; Sporothrix ; Sporotrichosis*

Drug-induced tubulointerstitial nephritis is one cause of acute kidney injury. Although traditional remedies have been widely used in South Korea, Dioscorea quinqueloba-induced tubulointerstitial nephritis has not been reported in the general population. A 72-year-old male patient was transferred to our hospital with pulmonary edema, oliguria, decreased mentality, severe generalized edema after taking D. quinqueloba 25 days ago. His initial lab findings showed a blood urea nitrogen level of 43.4 mg/dL, a creatinine level of 5.3 mg/dL. Urinalysis revealed SG (1.015), blood (many), protein (++) and WBC (0-3/HPF). Kidney biopsy demonstrated severe mononuclear cell infiltration into the renal interstitium with mild tubular atrophy. Aggressive renal replacement therapy and supportive care resulted in gradual restoration of his renal function. This case implies that D. quinqueloba may be one cause that induces tubulointerstitial nephritis in some patients.
Acute Kidney Injury ; Aged ; Atrophy ; Biopsy ; Blood Urea Nitrogen ; Creatinine ; Dioscorea* ; Edema ; Humans ; Kidney ; Korea ; Male ; Nephritis, Interstitial* ; Oliguria ; Pulmonary Edema ; Renal Replacement Therapy ; Urinalysis

Drug-induced interstitial nephritis is one cause of acute kidney injury. Although traditional remedies have been widely used in South Korea, Corni fructus-induced interstitial nephritis has not been reported in the general population. A 65-year-old female patient was admitted with sudden onset of gross hematuria after ingesting Corni fructus tea for 2 weeks. Her initial lab findings showed a blood urea nitrogen level of 35.1 mg/dL, creatinine level of 1.7 mg/dL, albumin level of 4.5 g/dL, and hemoglobin level of 10.3 g/dL. Urinalysis revealed SG (1.025), blood (many), protein (+), and WBC (0-3/HPF). Her 24-hour total protein level was 1,120 mg/day. No specific abnormalities were found on serum and urine protein electrophoresis. Kidney biopsy demonstrated severe mononuclear cell infiltration into the renal interstitium with mild tubular atrophy and pericapsular fibrosis. Immediate withdrawal of Corni fructus, appropriate education, and conservative management resulted in gradual restoration of her renal function. This case implies that Corni fructus may be a causative allergen that induces acute interstitial nephritis in some patients.
Acute Kidney Injury ; Aged ; Atrophy ; Biopsy ; Blood ; Blood Urea Nitrogen ; Cornus ; Creatinine ; Education ; Electrophoresis ; Female ; Fibrosis ; Hematuria ; Hemoglobins ; Humans ; Kidney ; Nephritis, Interstitial* ; Pyridines ; Republic of Korea ; Tea ; Thiazoles ; Urinalysis ; Urine

Drug-induced interstitial nephritis is one cause of acute kidney injury. Although traditional remedies have been widely used in South Korea, Corni fructus-induced interstitial nephritis has not been reported in the general population. A 65-year-old female patient was admitted with sudden onset of gross hematuria after ingesting Corni fructus tea for 2 weeks. Her initial lab findings showed a blood urea nitrogen level of 35.1 mg/dL, creatinine level of 1.7 mg/dL, albumin level of 4.5 g/dL, and hemoglobin level of 10.3 g/dL. Urinalysis revealed SG (1.025), blood (many), protein (+), and WBC (0-3/HPF). Her 24-hour total protein level was 1,120 mg/day. No specific abnormalities were found on serum and urine protein electrophoresis. Kidney biopsy demonstrated severe mononuclear cell infiltration into the renal interstitium with mild tubular atrophy and pericapsular fibrosis. Immediate withdrawal of Corni fructus, appropriate education, and conservative management resulted in gradual restoration of her renal function. This case implies that Corni fructus may be a causative allergen that induces acute interstitial nephritis in some patients.
Acute Kidney Injury ; Aged ; Atrophy ; Biopsy ; Blood ; Blood Urea Nitrogen ; Cornus ; Creatinine ; Education ; Electrophoresis ; Female ; Fibrosis ; Hematuria ; Hemoglobins ; Humans ; Kidney ; Nephritis, Interstitial* ; Pyridines ; Republic of Korea ; Tea ; Thiazoles ; Urinalysis ; Urine

No abstract available.
Animals ; Antibody Formation* ; Immunoglobulin E* ; Mice* ; Poly I-C*

Exercise-induced anaphylaxis can be associated with ingestion of a specific food. We experienced a case of exercise-induced anaphylaxis followed by ingestion of parsely. A 22- year old female patient was presented with angioedema of the face and chest tightness induced by running after ingestion of parsley within 15 minutes. She had suffered from allergic rhinitis. She had positive reactions to mugwort pollen and parsely extract on skin prick test in a dose dependent manner. Although the oral provocation test with parsely could not induce bronchoconstriction, we could diagnosed as parsely dependent exercise induced anaphylaxis based upon skin prick test and history.
Anaphylaxis ; Angioedema ; Artemisia ; Bronchoconstriction ; Eating ; Female ; Humans ; Petroselinum ; Pollen ; Rhinitis ; Running ; Skin ; Thorax

Peritonitis is a major cause of morbidity in peritoneal dialysis patients; however, Aeromonas caviae rarely causes peritonitis in these patients. We report peritonitis due to A. caviae in a 72-year-old male with end-stage renal failure who had been undergoing automated peritoneal dialysis for 1 year. The white blood cell (WBC) count in the peritoneal fluid was 2,722/mm3 with 85% neutrophils. Gram staining of the peritoneal fluid yielded Gram-negative rods. Empirical antibiotic therapy with ceftriaxone was initiated intraperitoneally. However, drug sensitivity testing revealed that the organism was resistant. On the third hospital day, A. caviae was cultured from the peritoneal effluent, and the antibiotic regimen was switched to ciprofloxacin. The patient recovered rapidly and the WBC count of the peritoneal effluent decreased. He was discharged and the intraperitoneal ciprofloxacin therapy was continued for 14 days. The peritoneal catheter was not removed.
Aeromonas ; Aeromonas caviae ; Animals ; Ascitic Fluid ; Catheters ; Ceftriaxone ; Ciprofloxacin ; Guinea Pigs ; Humans ; Kidney Failure, Chronic ; Leukocytes ; Male ; Neutrophils ; Peritoneal Dialysis ; Peritonitis

PURPOSE: Increasing evidence suggests that Randalls plaque contributes to the pathogenesis of urinary stone formation. The purpose of our study is to compare the incidence of the abnormal metabolic stone risk factors between the calcium stone former with papillary calcification and the calcium stone former without papillary calcification on unenhanced spiral computed tomography (CT). MATERIALS AND METHODS: A series of patients with calcium stones (n=49) underwent unenhanced spiral CT and complete metabolic evaluation after they consumed a random diet for 1 month after stone removal. Of the 49 patients, 38 patients showed papillary calcification on unenhanced spiral CT and 11 patients did not. Their blood was evaluated by using a multichannel analysis sequential multichannel autoanalyzer (SMA)-20 and PTH tests. The 24-hour urinary constituents were assayed for calcium, oxalate, citrate, total volume, phosphorus and sodium. We compared the incidence of abnormal metabolic risk factors between the two groups. Statistical analysis was performed by chi-square tests. RESULTS: The incidences of hyperuricemia were 27.3% in the patients without papillary calcification and 31.6% in the patients with papillary calcification. The incidences of hypernatriuria were 18.2% versus 42.1%, the incidences of hypercalciuria were 36.4% versus 26.3%, the incidences of hyperuricosuria were 18.2% versus 18.4%, the incidences of hyperoxaluria were zero versus 28.9%, and the incidences of hypocitraturia were 45.5% versus 44.7%, respectively. The difference between the two groups was statistically significant only for hyperoxaluria (p=0.043). CONCLUSIONS: Hyperoxaluria is the only metabolic risk factor that more frequently occurred in the patients with papillary calcification. Our date suggest that hyperoxaluria may be an important factor in the pathogenesis of papillary calcification.
Calcium ; Citric Acid ; Diet ; Humans ; Hypercalciuria ; Hyperoxaluria ; Hyperuricemia ; Incidence ; Phosphorus ; Risk Factors* ; Sodium ; Tomography, Spiral Computed* ; Urinary Calculi

To evaluate and compare the clinical results of implantation of the Silicone and Acrysof IOLs in early postoperative period(to 3 months), we retrospectively analyzed 30 patients who had taken clear cornea incision and been implanted with Silicone IOL in one eye and Acrysof IOL in the other eye. There were no statistically significant difference in postoperative corrected visual acuity, corneal edema and postoperative astigmatic changes between silicone and acrysof IOLs. But, the rates of postoperative capsular fibrosis and contracture of Silicone IOL was higher than those of Acrysof IOL. In conclusion, in the degree and rate of after-cataract, Acrysof IOLs are more useful than silicone IOLs; therefore, more excellent in longterm visual prognosis. Further studies will be needed for the evaluation of clinical safety and efficacy.
Contracture ; Cornea ; Corneal Edema ; Fibrosis ; Humans ; Prognosis ; Retrospective Studies ; Silicones* ; Visual Acuity

Orbital infarction syndrome is defined as ischemia of all intraorbital and intraocular structures and is a rare disorder due to rich anastomotic vascularization of the orbit. It results in orbital and ocular pain, total ophthalmoplegia, anterior and posterior segment ischemia, and acute bindness. It can occur secondary to different mechanisms such as acute perfusion failure, systemic vasculitis, orbital cellulitis and vasculitis. We experienced a case of orbital infarction syndrome in a 61-year-old nonketotic diabetic woman who had developed paranasal sinusitis by mucormycosis and presented orbital cellulitis, multiple nerve paralysis, chorioretinal ischemia, facial necrosis around orbit and acute blindness. Prompt recognition of clinical pictures and rapid diagnosis is essential for early treatment of orbital infarction due to rhino-orbitocerebral mucormycosis because its progression is very rapid and fatal.
Blindness ; Diagnosis ; Female ; Humans ; Infarction* ; Ischemia ; Middle Aged ; Mucormycosis* ; Necrosis ; Ophthalmoplegia ; Orbit* ; Orbital Cellulitis ; Paralysis ; Perfusion ; Sinusitis ; Systemic Vasculitis ; Vasculitis