556 Monocular blinded men were observed, and results were as following. 1) 500 patients (89.9%) had visuial acuity of 20/20 or better in the fellow eye. 2) 56 patients (10.1%) were ametropia.
Humans ; Male ; Refractive Errors

Treatment of persistent uveitis with Methotrexate (MTX) in a 35 years-old Korean male has been reported. The patient vision was HM in right eye and 0.02 in left eye on admission, and improved to 0.2 in right eye and 1.0 in left eye after MTX treatment for 45 days. A brief review of literatures has also been described.
Adult ; Humans ; Male ; Methotrexate* ; Uveitis*

A case of Coats' disease, apparently as the first report in Korea, is presented. The patient was 17 years old Korean female and hospitalized Woo-Suk University hospital on May 23, 1969. Although cyclodialysis had been performed to the patient her intraocular pressure remained as the same as before the treatment, and thus enucleation Was done finally.
Adolescent ; Female ; Humans ; Intraocular Pressure ; Korea

The purpose of this study were to determine that dexamethasone(Dex) induces differentiation of periodontal ligament(PDL) cells to osteoblastic cells and to investigate expression of matrix Gla protein(MGP), which is one of bone matrix protein. The isolated human PDL cells and gingival fibroblasts were prepared and cultured. The fourth or sixth subpassage cells were used in this experiments. control group, ascorbic acid and beta-glycerophosphate treated group, ascorbic acid, beta-glycerophosphate and 100nM Dex treated group, ascorbic acid, beta-glycerophosphate, and 5micrometer Dex treated group were made for study. The results were as follows: Cellular morphological change of PDL cells according to time was investigated. At first, the cells exhibited confluent monolayer of spindle or polygonal appearance. The multilayer of cells were seen after 7 days of treatment. After 14 days, the cells lost polarity and were densely packed. The mineralized nodule formation was seen at 21 days in the only Dex treated PDL cell groups. In the gingival fibroblast groups and no Dex treated PDL cell groups, the mineralized nodule was not seen. The mineralized nodule formation of 5micrometer Dex treated group was higher than 100 nM Dex treated group. Alkaline phosphatase(ALP) activity was higher in the Dex treated PDL cell groups of 14 and 21 days than 0 and 7 days. MGP was expressed in the control and all experimental groups and the expression was constant at 0, 7, 14, 21 day. The above results confirm that Dex is affected to differentiation of the PDL cells to osteoblastic or cementoblastic cells and has dose-dependent effect for mineralization. And, MGP is expressed in the PDL cells and is not affected to mineralization of PDL cells.
Ascorbic Acid ; Bone Matrix* ; Dental Cementum ; Dexamethasone* ; Fibroblasts ; Gene Expression* ; Humans ; Osteoblasts ; Periodontal Ligament*

BACKGROUND: Recently, a lower incidence of late potentials has been reported in patients with acute myocardial infarction after successful thrombolysis when compared with conventionally treated patients. In another recent study, however, no significant effect of thrombolytic therapy on any abnormal signal average electrocardiography was found at 13 days after acute myocardial infarction. The present study was designed to determine the prognostic significance of the signal average electrocardiography and to evaluate the possible value of this technique as a noninvasive tool for monitoring of coronary occlusion and reperfusion. METHODS: Signal averaging was performed by using a signal average electrocardiography with bidirectional filterings before coronary artery occlusion, at 5 minutes after coronary occlusion and on reperfusion in 20 cats. Three of them died due to malignant ventricular arrhythmia during reperfusion. In all cats, approximately 250 beats were averaged. All data were analysed at filter frequency 25 to 250Hz, 40 to 250Hz and 80 to 250Hz. The following quantitative high resolutional electrocardiographic variables were calculated by computer : 1) filtered total QRS duration, 2) duration of HFLA(high frequency low amplitude) signals under 40uV, 3) RMS voltage of terminal 40ms, 4) mean Voltage of terminal 40ms, 5) average noise voltage. RESULTS: At the filter frequency of 40 to 250Hz and 80 to 250Hz, the filtered QRS duration and duration of HFLA signals 40uV were significantly prolonged at 5 minutes after coronary artery occlusion than before coronary occlusion(p<0.01). At the filter frequency of 40 to 250Hz and 80 to 250Hz, the RMS voltage(terminal 40ms) and mean voltage(terminal 40ms) were significantly prolonged at 5 minutes after coronary artery occlusion than before coronary occlusion(p<0.01, p<0.01 respectively). At the filter frequency of 80 to 250Hz, the filtered QRS duration and at the filter frequency of 25-250Hz, the duration of HFLA signals at 40uV were significantly shortened during reperfusion than at 5 minutes after coronary artery occlusion(p<0.01, p<0.05 respectively). At the filter frequency of 40 to 250Hz and 80 to 250Hz, the RMS voltage(terminal 40ms) and mean Voltage(terminal 40ms) were significantly shortened during reperfusion than at 5 minutes after coronary artery occlusion(p<0.01, p<0.01 respectively). There was no significant change of the filtered QRS duration, duration of HFLA signals 40uV,RMS voltage(terminal 40ms) and mean Voltage(terminal 40ms) after reperfusion compared with those of control at the filter frequency of 25 to 250Hz, 40 to 250Hz and 80 to 250Hz respectively. CONCLUSION: These results suggest that the signal average electrocardiography could be a valuable tool for monitoring the state of coronary artery occlusion and reperfusion.
Animals ; Arrhythmias, Cardiac ; Cats* ; Coronary Occlusion ; Coronary Vessels* ; Electrocardiography* ; Humans ; Incidence ; Myocardial Infarction ; Noise ; Reperfusion* ; Thrombolytic Therapy

Primary pericardial mesothelioma is a rare tumor of mesodermal origin that is infrequently diagnosed antemortem and survival is short. A 60 year old male case of pericardial mesothelioma (epitheloid type) is reported. He was admitted to Yeungnam University Hospital because of chest pain, dyspnea, orthopnea and nonproductive cough. Chest x-ray suggested pericardial effusion. 2-D echocardiography showed echo free spaces of massive pericardial effusion and areas of thick hyperrefractile echoes arising from the pericardium. Pericardiocentesis was attempted and aspirated fluid was bloody exudates. Pericardial window operation with biopsy was done. Swan-Ganz catheterization showed equalization between right atrial pressure and pulmonary capillary wedge pressure. The pathologic diagnosis was established by histologic finding at pericardial biopsy.
Atrial Pressure ; Biopsy ; Catheterization, Swan-Ganz ; Chest Pain ; Cough ; Diagnosis ; Dyspnea ; Echocardiography ; Exudates and Transudates ; Humans ; Male ; Mesoderm ; Mesothelioma* ; Pericardial Effusion ; Pericardiocentesis ; Pericardium ; Pulmonary Wedge Pressure ; Thorax

OBJECTIVE: Chlamydia trachomatis is one of the most common causative microorganisms in pelvic inflammatory disease. The symptom of Chlamydia infection is nearly absent or weak in many cases, but its complication is clinically very important because of tubal obstruction, infertility, tubal pregnancy, and recurrent pelvic inflammatory disease. This study was performed to investigate the prevalence rate and clinical characteristics of Chlamydia trachomatis. METHODS: From May, 2001 to April, 2002, in Daerim St. Mary's Hospital, OB-Gyn department, the 68 inpatients of pelvic inflammatory diseases and 607 outpatients of routine gynecologic examination were studied on history taking, physical examination, laboratory test, and polymerase chain reaction for the detection of Chlamydia trachomatis. RESULTS: The prevalence rate of Chlamydia trachomatis was 20.6% (14/68) in pelvic inflammatory disease and 8.6% (51/593) in routine gynecologic examination. As regarding the age distribution of Chlamydia trachomatis positive group was the largest portion in the twenties, and symptom-free group was about 40%. Chlamydia infection was related to the history of artificial abortion, and showed no significant difference in parity. Most common site of infection was uterine cervix, and mixed infection rate with other bacteria was 43.1%. The treatments were given medically in 58 cases, surgically in 6 cases, and laparoscopy in 1 case were performed. CONCLUSION: Although the prevalence rate of Chlamydia infection is high in sexually active age group and Chlamydia infection has a serious bad effect on reproduction, the disease detection is difficult because symptom is weak or absent, but it reveals good cure rate. Therefore the screening and treatment of Chlamydia trachomatis are necessary to decrease the prevalence and prevention of complication.
Age Distribution ; Bacteria ; Cervix Uteri ; Chlamydia Infections ; Chlamydia trachomatis* ; Chlamydia* ; Coinfection ; Fallopian Tube Diseases ; Female ; Humans ; Infertility ; Inpatients ; Laparoscopy ; Mass Screening ; Outpatients ; Parity ; Pelvic Inflammatory Disease ; Physical Examination ; Polymerase Chain Reaction ; Pregnancy ; Pregnancy, Tubal ; Prevalence ; Reproduction

A 67-Year-old male patient was adimitted due to aggravation of long-standing left moter weakness. Past history revealed weakness of left extremity for 20 years caused by CVD attack. On adimission, his mental state was drowsy and brain CT scan showed a round mass mimicking a brain tumor in the frontal horn of right lateral ventricle with asymmetric dilatation of lateral ventricles. After failed carotid angiography due to vascular tortuosity, his mental state was progressively deteriorated and left hemiparesis aggravated. A right external ventricular drainage was done, and 5 days later a craniotomy was performed under the impression of the intraventricular tumor causing obstruction of right foramen of Monro, but a large thrombosed aneurysmal sac was found intraoperatively. Retrial of carotid angiography revealed a large anterior communicating artery aneurysm. After second operation, maningoencephalitis with wound infection was complicated. Twenty days after second operation, clipping of the aneurysmal neck with removal of partially thrombosed aneurysmal sac was performed successfully.
Aged ; Aneurysm ; Angiography ; Animals ; Brain ; Brain Neoplasms ; Cerebral Ventricles ; Craniotomy ; Dilatation ; Drainage ; Extremities ; Horns ; Humans ; Hydrocephalus* ; Intracranial Aneurysm* ; Lateral Ventricles ; Male ; Neck ; Paresis ; Tomography, X-Ray Computed ; Wound Infection

No abstract available.
Lung Diseases, Interstitial*

Diabetic ketoacidosis is an acute complication of type 1 diabetes mellitus, which is observed frequently in routine autopsies. However, there are limitations of postmortem diagnosis of diabetic ketoacidosis. Clinical diagnostic criteria of the disease are not applicable to postmortem diagnosis because of the postmortem changes of the body; hence, diagnostic morphological changes cannot be observed. We report the case of a 47-year-old man that was diagnosed with diabetic ketoacidosis via routine autopsy and laboratory tests without information regarding his medical history. Additionally, we present a brief literature review.
Autopsy* ; Diabetes Mellitus, Type 1 ; Diabetic Ketoacidosis* ; Diagnosis* ; Humans ; Middle Aged ; Postmortem Changes