No abstract available.
Colon, Descending* ; Leiomyosarcoma*

No abstract available.
Wandering Spleen*

Autograft is frequently used to restore anatomic morphology and functional properties in bone defects. Disadvantages of the autograft are related to donor site morbidity and include the risk of wound infection, increased blood loss and additional postoperative discomfort. Allograft and xenograft, which are currently employed as the most common alternative to autografts, encounter the complications such as fracture, resorption and nonunion secondary to immunologic rejection. These volumetric and immunologic concerns with biologic implants have stimulated interest in the potential for synthetic, bioinert materials as bone graft substitutes. Hydroxyapatite (HA), a calcium phosphate ceramic, is a well known biocompatible artificial bone substitite without induction of systemic toxic and foreign body reactions. Bone conduction usually occurrs by the implanted HA but biodegradation of HA is poor and the bone formation around HA is slow. Carbonate apatite has been known as that the physicochemical properties are similar of the natural bony apatite and demonstrates no toxic reactions with better biodegradation. Carbonate apatite collagen composite was reported to show more bone formation and biodegradation than hydroxyap atite. In this study, the composite (CA-C) consisted of carbonate apatite and type I collagen was implanted in rabbit tibiae to evaluate the possibility as an artificial bone substitute. Forty HA (HA group) and forty CA-C (CA-C group) were applied in 80 dissected rabbit tibiae and fixed by external fixators. For biomechanical study, the rabbits were sacrificed and the specimens were obtained in 2, 4, 6 and 8 weeks after implantation. Tensile load was applied to the prepared tibiae in Instron and biomechanical properties were investigated. The fracture at the callus occurred as transverse or short oblique fracture in the vertical direction to the axis of applied tensile load. In each group, the tensile strength at breaking point increased significantly with time and at 4 weeks more prominent increase in break strength was observed (p<0.05). HA group showed higher mean strength before 6 weeks and at 8 weeks CA-C group higher mean strength but statistical significance could not be found. There was no significant difference in extension length at breaking point between both groups and time intervals. In summary, carbonate apatite collagen composite revealed similar biomechanical properties as hydroxyapatite, suggesting its clinical usefulness as a bone substitute, but it will be necessary to improve biodegradational property, stiffness of carbonate apatite collagen composite.
Allografts ; Autografts ; Axis, Cervical Vertebra ; Bone Conduction ; Bone Substitutes ; Bony Callus ; Calcium ; Carbon* ; Ceramics ; Collagen Type I ; Collagen* ; Durapatite* ; External Fixators ; Foreign Bodies ; Heterografts ; Humans ; Osteogenesis ; Rabbits ; Tensile Strength ; Tibia* ; Tissue Donors ; Transplants ; Wound Infection

PURPOSE: We prospectively examined the effects on refractive power after strabismus surgery using suturing materials of different thickness. METHODS: Postoperative sutures were done using 6-0 vicryl on the right eye and 7-0 vicryl on the left eye in 16 patients (32 eyes) who received bilateral horizontal rectus muscle recessions. Cycloplegic refraction was performed preoperatively and at 1 week, 1 month, 3 months, and 6 months after surgery. RESULTS: We found a significant decrease in the refractive power at 180 degrees meridian resulting in with-therule astigmatism during the first month after surgery in the 6-0 vicryl group and during the first week in the 7-0 vicryl group. The changes in refractive power gradually returned to preoperative states in each group. There was no statistical significance between the two groups. However, the decrease in refractive power at the 180( meridian resulting in with the rule astigmatism was less in the 7-0 vicryl group. CONCLUSION: With-the-rule astigmatism after horizontal muscle recession surgery is a temporary phenomenon and this tendency is decreased with the use of thinner suture materials.
Astigmatism ; Humans ; Polyglactin 910 ; Prospective Studies ; Strabismus* ; Sutures

Tacrolimus(FK 506) is a powerful immunosuppressant. Recently, topical and systemic tacrolimus was known to have therapeutic effects in various dermatologic diseases such as atopic dermatitis, psoriasis, pyodema gangrenosum, and Beh et's disease. A 48-year-old woman presented with psoriasis of 40 years duration, which was recalcitrant to any therapies including topical steroids and calcipotriol, UVB, PUVA, acitretin, cyclosporine, and methotrexate. Therefore, systemic tacrolimus treatment, at a dose of 2 to 6 mg per day, was initiated, and complete resolution of the lesions was observed after 2 months. We report a case of recalcitrant psoriasis improved with tacrolimus.
Acitretin ; Cyclosporine ; Dermatitis, Atopic ; Female ; Humans ; Methotrexate ; Middle Aged ; Psoriasis* ; Steroids ; Tacrolimus*

Rheumatoid vasculitis usually occurs in patients with long standing, seropositive, erosive rheumatoid arthritis. It involves typically small to medium-sized vessels and is associated with peripheral neuropathy, digital gangrene, nail fold infarcts, livedo reticularis, and palpable purpura. Histologic examination of skin biopsy specimens usually shows leukocytoclastic vasculitis. We report a case of rheumatoid vasculitis developed on both extremities in a 63-year-old female with rheumatoid arthritis for 15 years.
Arthritis, Rheumatoid ; Biopsy ; Extremities ; Female ; Gangrene ; Humans ; Livedo Reticularis ; Middle Aged ; Peripheral Nervous System Diseases ; Purpura ; Rheumatoid Vasculitis* ; Skin ; Vasculitis

Neurofibroma may assume one of three growth patterns: localized, diffuse, or plexiform. The localized form is seen most commonly as a superficial, solitary tumor in normal individuals. Any area of the body may be involved in solitary neurofibroma, but the head and trunk appear to be affected usually. Involvement of the orbital cavity, nasal cavity, maxilla, and mandible has been reported, but the upper eyelid remains an unusual location for solitary neurofibroma. We report a case of solitary neurofibroma in a 55-year-old female patient, who presented with a 5-year history of 0.9 X 0.9cm sized, soft, dome-shaped nodule on the left upper eyelid with an unusual presentation.
Eyelids* ; Female ; Head ; Humans ; Mandible ; Maxilla ; Middle Aged ; Nasal Cavity ; Neurofibroma* ; Orbit

Angioleiomyoma is a solitary form of leiomyoma that usually occurs in the subcutis and is composed of numerous thick-walled vessels. It occurs more frequently in women and preferentially on the extremities, particularly the lower leg. The tumor is usually painful and tender. We report a rare case of asymptomatic angioleiomyoma occurring on the lower lip.
Angiomyoma* ; Extremities ; Female ; Humans ; Leg ; Leiomyoma ; Lip*

Acquired digital fibrokeratoma (ADFK) is a solitary round, firm and hyperkeratotic projection seen most commonly on the digits, but it is occasionally found on the palm, dorsum of the hand, wrist, periungual area, and rarely on the sole. We report herein three cases of ADFK in an adult occuring on the sole. As being continuously exposed to the pressure, ADFKs are transformed and may easily be mistaken for more common plantar lesions including plantar warts and corns.
Adult ; Callosities ; Hand ; Humans ; Warts ; Wrist ; Zea mays

BACKGROUND: The histologic distinction between basal cell carcinoma(BCC) and squamous cell carcinoma(SCC) is sometimes difficult, but clinically important, because SCC has worse prognosis than BCC. Cytokeratins(CKs) are the major component of intermediate filaments and are subdivided into at least 20 different polypeptides. Monoclonal antibodies developed against these individual keratins become very useful in the classification of the major types of epithelial tumors. OBJECTIVE: The purpose was to investigate the usefulness of CK staining in distinguishing BCC from SCC. METHODS: We studied 10 cases of BCC and 10 cases of SCC with 6 anticytokeratin antibodies including AE1, CAM5.2, CK7, CK16, CK10, and CK8. RESULTS: All cases of BCC and SCC stained with AE1. Six and 5 cases out of 10 cases of BCC stained with CAM5,2 and CK7, respectively, but all cases of SCC stained with neither CAM5.2 nor CK7. All cases of SCC stained with CK16, but all cases of BCC did not. Two out of 10 cases of SCC stained focally with CK10, while all cases of BCC did not stain with CK10. All cases of BCC and SCC did not stain with CK8. CONCLUSION: We conclude that a panel of antibodies for CKs including CK7, CAM5.2, and CK16 may be useful in distinguishing BCC from SCC. In particular, CK16 may be the most useful marker because it was positive for all cases of SCC while negative for all cases of BCC.
Antibodies ; Antibodies, Monoclonal ; Carcinoma, Basal Cell* ; Carcinoma, Squamous Cell* ; Classification ; Intermediate Filaments ; Keratins* ; Peptides ; Prognosis