Acrospiroma is a rare benign tumor and a clinicopathologically distinctive neoplasm differentiating toward the distal part of the eccrine sweat gland. I experienced a case of dermal acrospiroma in a 59-year-old man who had a 7.0x6.5 x 5.3 cm sized, slowly growing, brown colored, smooth-surfaced mass on the right scrotum for 3 years. Histological examination revealed lobular structures composed of small fusiform cells and large eosinophilic polyhedral cells. Histochemically some of large polyhedral cells had PAS-positive DPAS-negative glycogen and Alcian-positive mucin in cytoplasm. Immunohistochemical stainings for vimentin, S-100, low molecule keratin, and EMA were positive in the tumor cells. During 6 months follow up period after excision, there was no recurrence. However, it is necessary to follow up for a long period because some acrospiroma may recur after a long silence period.
Acrospiroma* ; Cytoplasm ; Eosinophils ; Follow-Up Studies ; Glycogen ; Humans ; Middle Aged ; Mucins ; Recurrence ; Scrotum* ; Sweat Glands ; Vimentin

No abstract available.

No abstract available.
Diagnosis* ; Ultrasonography* ; Varicocele*

Surgical results of 34 children (68 ureters) who underwent Cohen ureteral reimplantation in the last 6 years were evaluated. All children were followed at least 4 months after the operation. Indication for the repair consisted of vesicoureteral reflux in 22 children, obstructive megaureter in 8 children and ureterocele in 4 children. The underlying problems in 55 ureters ( 94.8% ) were successfully corrected. Surgical failures were persistent reflux in 2 ureters, new ipsilateral reflux in 1 ureter and contralateral reflux in 1 ureter. However, no ureteral obstruction was noticed in this series. In conclusion, the Cohen cross trigonal technique was a safe and effective method of ureteral reimplantation in children.
Child* ; Humans ; Replantation* ; Ureter* ; Ureteral Obstruction ; Ureterocele ; Vesico-Ureteral Reflux

No abstract available.
Urinary Bladder Neoplasms* ; Urinary Bladder*

PURPOSE: To determine if the urine specific gravity(SG) plays a role in enuresis, the first morning urine SG of the healthy preschool nocturnal enuretic was compared with that of the nonenuretic. The results of desmopressin were analyzed according to the pretreatment urine SG to know if the urine SG can predict the responsiveness of the medication. MATERIALS AND METHODS: Five hundred twenty healthy preschool children aged 3-6 years were entered in this prospective observer-blinded study. A comparison was made between SG of the first morning urine specimen and results of questionnaire concerning the bed wetting and voiding habits of children. The responsiveness to oral desmopressin(0.2-0.4mg h.s.) in 14-day treatment periods was also analyzed according to the urine SG in 28 children with enuresis. The responder group was defined as a reduction of at least 50% from the number of wet night. RESULTS: The incidence of enuresis was 8.6 percent. Stastistically significant difference was found between the bedwetter and nonbedwetter group with regard to the urine SG(p<0.05). The overall response rate of desmopressin was 68 percent. There was no significant difference between the responder and nonresponder group with respect to urine SG. CONCLUSIONS: The first morning urine of the enuretic showed higher probability of lower level of the SG than that of the nonenuretic. Treatment with desmopressin was associated with a significant decrease in the number of wet night, but clinical response was not predictable based on the first morning urine SG.
Child ; Child, Preschool* ; Deamino Arginine Vasopressin ; Enuresis* ; Humans ; Incidence ; Prospective Studies ; Surveys and Questionnaires

PURPOSE: Penile paraffinoma provokes many serious undesirable effects. We studied our series retrospectively to evaluate the outcome of surgical treatment according to the degree of penile skin defect after excision of the lesion. PATIENTS AND METHODS: Surgical treatment for penile paraffinoma was performed in 42 patients over 6 years. The operative methods were complete excision with primary closure (N=34) or bilateral pedicle scrotal flap (N=8). RESULT: The complications of bilateral pedicle scrotal flap were wound infection in 1 case and skin defect in 1 case. There were no complications of primary closure. CONCLUSIONS: We propose that the proper treatment of penile paraffinoma is complete excision with primary closure for a small denuded penis and bilateral pedicle scrotal flap for a large denuded penis.
Humans ; Male ; Paraffin ; Penis ; Retrospective Studies ; Skin ; Wound Infection

We evaluated a clinical usefulness of prostate specific antigen (PSA) as a tumor marker for prostate cancer. Serum PSA values were obtained from 32 patients with prostatic adenocarcinoma(group I ),81 with histologically diagnosed BPH(group II ) and 147 with clinically diagnosed BPH(group III). Mean PSA values were 121.5, 9.3 and 3.6ng/ml, respectively. To enhance the accuracy of serum PSA, we have used the quotient of serum PSA and prostatic volume, PSA density. In group I, 31 patients(97%) had PSA values over 10ng/ml and PSA density over 0.15. In group II, 27 patients(33%) had PSA values over 10ng/ml and 35(43%) had PSA density over 0.15. The PSA values of extraprostatic cancer were higher than that of organ-confined cancer in group I (p<0.05). Among 3 groups divided by combined Gleason score, low 2-4, intermediate 5-7 and high 8-l0, statistically significant differences were not noticed in PSA values (p > 0.05). Of 18 patients with stage D2 prostate cancer treated with orchiectomy, 11 had PSA values decreased to normal range within 6 months. Serum PSA values of 2 patients who have clinically progressive disease were increased after 6 months. In 3 of 4 patients treated with radiotherapy during follow-up of 18 months, post irradiation PSA values were 2.4, 5.6 and 11.2ng/ml, respectively. Only 1 patient who have a positive bone scan had an elevated PSA value of more than 100ng/ml. We suggest that serum PSA is not a excellent marker on screening test for prostate cancer because of a high false positive rate. However, PSA is useful for following disease progression, response to therapy and determining indication of bone scan.
Disease Progression ; Follow-Up Studies ; Humans ; Mass Screening ; Neoplasm Grading ; Orchiectomy ; Prostate* ; Prostate-Specific Antigen* ; Prostatic Neoplasms* ; Radiotherapy ; Reference Values

Prostate specific antigen (PSA) has become established as the most useful serological marker for monitoring patients with prostate cancer. However, the benefits of serum PSA values are controversial in screening procedures for prostate cancer due to the rather low specificity of PSA test. To determine if different assays yield comparable results, we compared the IMx PSA enzyme immunoassay and the ELSA PSA monoclonal immunoradiometric assay. We analyzed 72 serum specimens from 68 patients with prostatic disease (12 patients with cancer, 47 benign hyperplasia and 9 prostatitis) and 13 from normal controls by both assays. Results from the assays revealed close linear correlation but the ELSA PSA assay yielded values 1.5 times those of the IMx PSA assay In 13 patients with histologically diagnosed benign prostatic hyperplasia, number of patient with PSA value over l0 ng/ml measured by IMx and ELSA assay were 2(15% ) and 4(31%), respectively. We conclude that the proportional bias between assays demonstrates a need for improved standardization of PSA assays.
Bias (Epidemiology) ; Humans ; Hyperplasia ; Immunoenzyme Techniques* ; Immunoradiometric Assay* ; Mass Screening ; Prostate-Specific Antigen ; Prostatic Diseases ; Prostatic Hyperplasia ; Prostatic Neoplasms ; Sensitivity and Specificity

No abstract available.
Peripheral Nerves*