1.A screening method for neuroblastoma and organic acidemias by gas chromatography-mass spectrometry.
Hyun Gyung JANG ; Soo Kyung PARK ; Bong Chul CHUN ; Jongsei PARK
Journal of Korean Society of Endocrinology 1992;7(3):280-287
No abstract available.
Gas Chromatography-Mass Spectrometry*
;
Mass Screening*
;
Neuroblastoma*
2.3 Cases Report of Myositis Ossificans Progressiva
Joon Young KIM ; Choo Bong CHUN ; Woo Suck WHANG ; Chul Yong CHUNG ; Young Joe KIM
The Journal of the Korean Orthopaedic Association 1972;7(2):228-234
Myositis Ossificans progressiva is a very rare disease and not more than five cases have been reported in this country. The symptoms usually appear before the age of six and no case has ever been reported in medical literature in which patient is older than the age of twenty. This author reports here that a 52 years old male was diagnoed as a myositis ossificans progressiva. The patient developed his symptoms when he was lynched by a club during the Korean conflict at the Korean conflict at the age of thirty. Another interesting fact is that is that his daughter has also developed similar symptoms which appeared following an accident when she was run over by an angry cow at the age of six.
Humans
;
Korean War
;
Male
;
Myositis Ossificans
;
Myositis
;
Nuclear Family
;
Rare Diseases
3.Illness Associated With Contamination Of Drinking Water Supplies With Phenol.
Doo Hie KIM ; Sung Kook LEE ; Byung Yeol CHUN ; Duk Hee LEE ; Sung Chul HONG ; Bong Ki JANG
Korean Journal of Preventive Medicine 1993;26(2):202-209
A accidental spills of phenol(100%) to the river Nakdong with subsequent contamination of the tap water for about two million consumers in Taegu city of Korea were occurred in March 1991. A historical cohort study of 6,913 individuals was undertaken to determine the associated with illness. Population subjects were divided into two groups of exposed and unexposed. Exposed subjects were reported to be phenol associated symptoms significantly higher than those in a nearby unexposed area(39.6% vs 9.4%, p<0.01). Especially, in the related symptoms, highly significant differences were noted in the number of subjects reporting gastrointestinal illness such as nausea, vomiting, diarrhea, or abdominal pain. During the accident, study subjects who experienced peculiar taste or odor in the tap water were significantly higher in the exposed areas(92% vs 34.3%). Chlorophenols formed from chlorination of water may have aggravated the problem.
Abdominal Pain
;
Chlorophenols
;
Cohort Studies
;
Daegu
;
Diarrhea
;
Drinking Water*
;
Drinking*
;
Equipment and Supplies*
;
Halogenation
;
Korea
;
Nausea
;
Odors
;
Phenol*
;
Rivers
;
Vomiting
;
Water
4.Clinical observation of acute drug intoxications.
Jun Ha CHUN ; Kyung Chul SHIN ; Jin Hong CHUNG ; Chong Ki LEE ; Bong Sup SHIM ; Hyun Woo LEE
Yeungnam University Journal of Medicine 1991;8(2):164-173
Clinical observations were made on 349 cases of acute drug intoxication who were visited to emergency room of Yeungnam University Hospital during recent 7 years from January 1984 to December 1990. The following results were obtained. 1) Total number of cases of acute drug intoxication was 349 which was 0.39% of the total patients of the emergency room during the same period. 2) The ratio of male to female was 1.1:1. The age incidence was highest in the third decade (26.7%). The monthly incidence was highest in May. Higher frequency was observed in summer season. 3) The most common drug of the intoxication was pesticides and herbicides (71.9%), the remainders were miscellaneous drugs (11.2%), sedatives (7.7%), rodenticides (6.3%) and unknown drug (3.2%) in orders. 4) The most common cause of drug intoxication was suicide (69.1%) and the others were accident, unknown cause, intention in orders. 5) Main clinical manifestations were the impairment of consciousness, nausea, vomiting and convulsion. Physical examination revealed increased pulses, increased blood pressure, miosis of the pupil and sweating. Above symptoms and signs were more prominent in pesticide intoxication. Leukocytosis, glycosuria and abnormal LFT were common findings in acute intoxications. 6) The complications were developed in 18.3% among 349 cases and the most common complication was respiratory failure, pneumonia, cardiovascular collapse and pulmonary edema in orders. 7) Overall mortality rate was 8.3% of total cases and mortality rate was highest in herbicide intoxication (22.2%).
Blood Pressure
;
Consciousness
;
Emergency Service, Hospital
;
Female
;
Glycosuria
;
Herbicides
;
Humans
;
Hypnotics and Sedatives
;
Incidence
;
Intention
;
Leukocytosis
;
Male
;
Miosis
;
Mortality
;
Nausea
;
Pesticides
;
Physical Examination
;
Pneumonia
;
Pulmonary Edema
;
Pupil
;
Respiratory Insufficiency
;
Rodenticides
;
Seasons
;
Seizures
;
Suicide
;
Sweat
;
Sweating
;
Vomiting
5.Interelationship Between Axial Length and Refractive States, and Anterior Chamber Depth in the Newborn.
Kwan Sic CHO ; Yoon Bo SHIM ; Bong Chul KIM
Journal of the Korean Ophthalmological Society 1990;31(2):215-219
The aims of the our study are investigation of the average value of the refraction, anterior chamber depth(ACD), axial length(AL), and the interrelationship of refraction, ACD, AL, weight and height of normal newborn infant. Objects of this study are 236 eyes of 118 normal newborn infants that have been examined with retinoscope under the cycloplegia and the axial length and anterior chamber depth have been measured by ultrasonogram. And so we gained following results. The average value of refraction(+1.85 +/- 1.86D), the average value of the AL(17.5 +/- 0.68mm) and the average value of ACD(2.62 +/- 0.21mm) did not show significant difference between male and female newborn infants. The correlation coefficient between AL and ACD. refraction and AL, weight and AL, and height and AL were 0.326(P<0.001), -0.305(0.001
0.1).
Anterior Chamber*
;
Female
;
Humans
;
Infant, Newborn*
;
Male
;
Retinoscopes
;
Ultrasonography
6.Refraction by Photo refraction.
Bong Chul KIM ; Kwan Sic CHO ; Yoon Bo SHIM ; Hanho SHIN
Journal of the Korean Ophthalmological Society 1989;30(2):283-287
Photorefraction was performed in 96 cases(191 eyes) after instillation of tropicamide and cyclopentolate for the purpose of screening procedure. And then refraction was also carried out by retinoscope. From this comparison study, phtorefraction provided data which were very close to those obtained from the conventional retinoscopy.
Cyclopentolate
;
Mass Screening
;
Retinoscopes
;
Retinoscopy
;
Tropicamide
7.A Case of Conjunctival Tuberculosis.
Gi Yong JUNG ; Bong Chul KIM ; Hanho SHIN
Journal of the Korean Ophthalmological Society 1987;28(6):1351-1355
Conjunctival tuberculosis, a very rare disease, is thought to be a relatively rare cause of ocular diseases. This is because of a decreased incidence of tuberculosis as well as lessened emphasis on its diagnosis. We have experienced a 19-years old female who had a injection and hypertrophic granulomatous inflammation, on the left lower palpebral conjunctiva. We performed excisional biopsy under the clinical diagnosis of the chronic conjunctivitis and confirmed the histopathological diagnosis of conjunctival tuberculosis. So, the literature of the conjunctival tuberculosis was briefly reviewed with clinical history.
Biopsy
;
Conjunctiva
;
Conjunctivitis
;
Diagnosis
;
Female
;
Humans
;
Incidence
;
Inflammation
;
Rare Diseases
;
Tuberculosis*
;
Young Adult
8.Muscle Strength and Functional Capacity after Arthroscopic ACL Reconstruction using Patellar Tendon Autograft.
Soon Chang BONG ; Sang Cheol SEONG ; Myung Chul LEE ; Young Wan MOON ; Tae Gyun KIM ; Young Chun PARK
The Journal of the Korean Orthopaedic Association 1997;32(7):1497-1505
Traditionally, evaluation after ACL reconstruction has been focused on physical characteristics and measures of knee stability. Recently, however, reliance on such criteria has been refuted based on the lack of a strong relationship between these measures and both the patient s perception of knee function and return to sports activity. In present study, preoperative and postoperative physical examinations, isokinetic dynamometer, arthrometer test and functional tests were performed on 17 patients with chronic anterior cruciate ligament tears treated by arthroscopic reconstruction using autogenous bone-patellar tendon-bone graft with at least 1 year of follow-up. Muscle power, joint stability and functional recovery were checked for functional evaluation by specific methods. Lysholm score rating scale and functional tests (single leg hop test, vertical jump test, timed single jump test) were performed preoperatively and 6, 12 months postoperatively. Pivot-shift test, Lachman test, anterior drawer test, thigh circumference index and Cybex II+ isokinetic dynamometer test were done preoperatively and at 3, 6, 12 months postoperatively. KT-2000 arthrometer test was done at last follow-up. Lysholm score has showed increasing tendency at 6, 12 months postoperatively (p < 0.01). In Cybex study, deficit percentage of peak torque and total work of the quadriceps and hamstrings was same or slightly decreased at 3, 6 months, but have decreased at 1 year follow-up (p < 0.01). Functional tests and physical examinations have also showed improving tendency at 12 months (p < 0.01). Arthrometer test revealed no significant laxity of the knee joint at last follow-up. In conclusion, muscle strengh and functional capacity in ACL reconstructed knee showed significant improvement at postoperative one year compared with preoperative status. It was considered that arthroscopic reconstruction using autogenous bone-patellar tendon-bone graft is one of the useful method for chronic anterior cruciate ligament injury.
Anterior Cruciate Ligament
;
Autografts*
;
Bone-Patellar Tendon-Bone Grafts
;
Follow-Up Studies
;
Humans
;
Humulus
;
Joints
;
Knee
;
Knee Joint
;
Leg
;
Muscle Strength*
;
Patellar Ligament*
;
Physical Examination
;
Sports
;
Thigh
;
Torque
9.Limited Sympathetic Nervelipping of T2 Sympathetic Chain Block for Essential Hyperhidrosis.
Man Sil PARK ; Chung Hun SEO ; Jae Chun SHIM ; Bong Chun CHOI ; Young Chul LEE
The Korean Journal of Thoracic and Cardiovascular Surgery 1999;32(9):813-817
BACKGROUND: Conventional thoracoscopic thoracic sympathectomy or sympathicotomy is an effective method in treating localized hyperhidrosis; however, this may result in a postoperatively embarrassing compensatory hyperhidrosis or facial anhidrosis in the treatment of palmar hyperhidrosis. We modified the conventional sympathicotomy by limiting the extent of nerve transection. The purpose of this study was to assess the result of the limited thoracoscopic sympathetic nerve transection in hyperhidrosis. MATERIAL AND METHOD: From May to August 1998, 17 patients underwent limited transection of the sympathetic nerve. For 9 patients with facial hyperhidrosis, we transected only the interganglionic fiber between the first and the second ganglion, whereas the conventional method cuts two interganglionic fibers. Eight patients with palmar hyperhidrosis underwent limited transection of the interganglionic fiber between the second and third ganglion. RESULT: Sixteen patients had improved symptom postoperatively. There was a recurred facial sweating in 1 patient 1 month after the operation. Among the 9 facial hyperhidrosis patients, postoperative compensatory hyperhidrosis was severe in 4, moderate in 4 and minimal in 1. But in 8 cases of palmar hyperhidrosis compensatory hyperhidrosis was moderate in 3, and minimal in 1, none in 4. Facial sweating was not disturbed postoperatively in all of the palmar hyperhidrosis patients. CONCLUSION: Limited sympathetic nerve transection is a practical and less invasive method for the treatment of localized hyperhidrosis and may reduce the incidence of compensatory truncal hyperhidrosis and facial anhidrosis in case of palmar hyperhidrosis.
Ganglion Cysts
;
Humans
;
Hyperhidrosis*
;
Hypohidrosis
;
Incidence
;
Sweat
;
Sweating
;
Sympathectomy
10.Effect of 17-beta Estradiol on Adipocyte Lipin-1 Expression in OLETF Rat.
Eun Seok KANG ; In Sook KIM ; Seok Jin KO ; Chul Hoon KIM ; Sung Wan CHUN ; Chul Woo AHN ; Bong Soo CHA ; Hyun Chul LEE
Endocrinology and Metabolism 2010;25(3):199-205
BACKGROUND: 17 beta-estradiol is known to play an important role in glucose homeostasis. Lipin-1 is a nuclear protein that is essential in adipocyte differentiation and it is considered to play a role in ectopic fat deposition and the redistribution of fat. The aim of this study was to evaluate the effect of 17 beta-estradiol on the lipin-1 expression in the adipocytes of OLETF rats, which is an animal model of diabetes. METHODS: The OLETF rats were divided into 3 groups, 1) the sham-operation group (SHAM) 2) the castrated group (CAST) and 2) the castrated and estradiol treatment group (EST), and all the rats were at 6 weeks of age. LETO rats were used as a control group (LETO). 0.1 mg of estradiol valerate was injected subcutaneously every 4 weeks in the rats of the EST group. The visceral and subcutaneous tissues were isolated to evaluate the lipin-1 protein expression. The lipin-1 expression was measured in human visceral and subcutaneous preadipocytes. RESULTS: Less body weight gain was observed in the EST group compared with that of the SHAM group. In addition, improvement in the glucose tolerance was observed in the EST group. The lipin-1 expression in visceral fat was decreased in the SHAM and CAST groups, but it was but recovered in the EST group. The lipin-1 expression in the subcutaneous fat was decreased in the SHAM, CAST, and EST groups. CONCLUSION: Long term estradiol treatment in OLETF rats reduces the body weight gain and improves the glucose tolerance. Estradiol enhances the lipin-1 protein expression in the visceral adipocytes, but not in the subcutaneous adipocytes.
Adipocytes
;
Animals
;
Body Weight
;
Estradiol
;
Glucose
;
Homeostasis
;
Humans
;
Intra-Abdominal Fat
;
Models, Animal
;
Nuclear Proteins
;
Rats
;
Rats, Inbred OLETF
;
Salicylamides
;
Subcutaneous Fat
;
Subcutaneous Tissue