3.Relationship between the gray level of X-ray photograph and the cortical thickness.
Hong-gang ZHONG ; Hai-bin BU ; Fu-hui DONG
China Journal of Orthopaedics and Traumatology 2008;21(3):194-195
OBJECTIVEIn order to get three dimensional measurements simply an plain X-ray photographs.
METHODSThe multi-layers of bone pieces were made by use of bone saw, and piled up to spiral ladder, which was used as a calibrating module for to living bone in clinics. The relationship between the cortical thickness and gray level of the X-ray photographs was obtained.
RESULTSThe correlation can be described with a cubic regression curve, and it can be simplified to a linear regression equation when cortical thickness is small than 3.8 mm.
CONCLUSIONIt can be realized to get three dimensional measures of the bone on plain X-ray photographs, by use of the bony spiral ladder described here.
Adult ; Bone and Bones ; chemistry ; diagnostic imaging ; Humans ; Radiography ; X-Rays
6.Advances in the medical imaging of multiple myeloma and related clinical significance.
Hai-Bo ZHANG ; Hua-Dan XUE ; Shuo LI
Acta Academiae Medicinae Sinicae 2014;36(6):671-674
Multiple myeloma is an incurable malignancy developed in the bone marrow plasma cell system. It usually consists of focal lesions of the bone,soft tissue lesions,and diffuse bone marrow infiltration. Currently,the diagnosis and follow-up of multiple myeloma are highly dependent on various medical imaging techniques.
Bone Marrow
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pathology
;
Bone and Bones
;
Diagnostic Imaging
;
Humans
;
Magnetic Resonance Imaging
;
Multiple Myeloma
;
diagnosis
8.Micro-CT evaluation and histological analysis of screw-bone interface of expansive pedicle screw in osteoporotic sheep.
Shi-yong WAN ; Wei LEI ; Zi-xiang WU ; Rong LV ; Jun WANG ; Suo-chao FU ; Bo LI ; Ce ZHAN
Chinese Journal of Traumatology 2008;11(2):72-77
OBJECTIVETo investigate the properties of screw-bone interface of expansive pedicle screw (EPS) in osteoporotic sheep by micro-CT and histological observation.
METHODSSix female sheep with bilateral ovariectomy-induced osteoporosis were employed in this experiment. After EPS insertion in each femoral condyle, the sheep were randomly divided into two groups: 3 sheep were bred for 3 months (Group A), while the other 3 were bred for 6 months (Group B). After the animals being killed, the femoral condyles with EPS were obtained, which were three-dimensionally-imaged and reconstructed by micro-CT. Histological evaluation was made thereafter.
RESULTSThe trabecular microstructure was denser at the screw-bone interface than in the distant parts in expansive section, especially within the spiral marking. In the non-expansive section, however, there was no significant difference between the interface and the distant parts. The regions of interest (ROI) adjacent to EPS were reconstructed and analyzed by micro-CT with the same thresholds. The three-dimensional (3-D) parameters, including tissue mineral density (TMD), bone volume fraction (BVF, BV/TV), bone surface/bone volume (BS/BV) ratio, trabecular thickness (Tb.Th), and trabecular separation (Tb.Sp), were significantly better in expansive sections than non-expansive sections (P less than 0.05). Histologically, newly-formed bony trabeculae crawled along the expansive fissures and into the center of EPS. The newly-formed bones, as well as the bones at the bone-screw interface, closely contacted with the EPS and constructed four compartments.
CONCLUSIONSThe findings of the current study, based on micro-CT and histological evaluation, suggest that EPS can significantly provide stabilization in osteoporotic cancellous bones.
Animals ; Bone Screws ; Bone and Bones ; diagnostic imaging ; pathology ; Female ; Osteoporosis ; diagnostic imaging ; pathology ; Sheep ; Tomography, X-Ray Computed
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