Sailonggu, a traditional Chinese medicine is whole skeleton of Myospalax baileyi, which is a kind of animal of rodent from Qinghai-Tibet Plateau of China. Osteon Myospalacem Baileyiis the first category medicinal materials of China Food and Drug Administration. For better quality control, a method of the morphological identification of Osteon Myospalacem Baileyi was established by means of studying characteristics of the animal skeleton, it's microscopic characteristics of powder, and literatures comparison. The characteristics of Osteon Myospalacem Baileyi were observed and recorded in detail and marked by number, which could be used for identifying crude drug of Osteon Myospalacem Baileyi efficiently.
Animals ; Bone and Bones ; anatomy & histology ; chemistry ; China ; Medicine, Chinese Traditional ; Rodentia ; anatomy & histology

The structure of cancellous bone is cellular. There are two basic models of cancellous bone structure namely the model of rod-rod structure and the model of framework of perforated plate. This paper presents several models of structure developed from the model of rod-rod structure to the model of framework of perforated plate. We computed the elastic modulus of cancellous bone based on these modes using homogenization. The relationship between the elastic modulus(E) of cancellous bone and the apparent density(p) was determined to be E = 1.78rho1.88.
Biomechanical Phenomena ; Bone Density ; Bone and Bones ; anatomy & histology ; Elasticity ; Humans ; Models, Anatomic ; Stress, Mechanical

The X-ray synchrotron is quite different from conventional radiation sources. This technique may expand the capabilities of conventional radiology and be applied in novel manners for special cases. To evaluate the usefulness of X-ray synchrotron radiation systems for real time observations, mouse fetal skeleton development was monitored with a high resolution X-ray synchrotron. A non-monochromatized X-ray synchrotron (white beam, 5C1 beamline) was employed to observe the skeleton of mice under anesthesia at embryonic day (E)12, E14, E15, and E18. At the same time, conventional radiography and mammography were used to compare with X-ray synchrotron. After synchrotron radiation, each mouse was sacrificed and stained with Alizarin red S and Alcian blue to observe bony structures. Synchrotron radiation enabled us to view the mouse fetal skeleton beginning at gestation. Synchrotron radiation systems facilitate real time observations of the fetal skeleton with greater accuracy and magnification compared to mammography and conventional radiography. Our results show that X-ray synchrotron systems can be used to observe the fine structures of internal organs at high magnification.
Animals ; Bone and Bones/*anatomy & histology/radiography ; Female ; Fetus/*anatomy & histology/radiography ; Histocytochemistry ; Mice ; Mice, Inbred ICR ; Pregnancy ; Synchrotrons ; X-Rays

The postmortem stature was measured in 57 Korean adult males (age range: 20-86 years old, mean: 52.3 years old) in supine position. After dissection of the corpses, we measured the maximum length of the remaining limb-bones (humerus, radius, ulna, femur, tibia and fibula). The correlation coefficients between the stature and each limb-bone length were calculated. Simple regression equations for estimating stature from each limb-bone length and multiple regression equations from the combination of limb-bone lengths were also obtained.
Adult ; Aged ; Aged, 80 and over ; Body Height* ; Bone and Bones/anatomy & histology* ; Extremities/anatomy & histology* ; Human ; Male ; Middle Age ; Regression Analysis

OBJECTIVETo compare the differences between bone-length measurements on human head and to probe proportion relation of the position of head points.

METHODSOne hundred healthy adult volunteers, aged between 18-25 years, 50 males and 50 females, were randomly selected, and their height, body weight, the distances from Shenting (GV 24) to Toulinqi (GB 15), from Shenting to Touwei (ST 8), between bilateral Touwei (ST 8), between the two Mastoid, from Yintang (EX-HN 3) to front hairline, front hairline to Naohu (GV 17), Naohu to Fengfu (GV 16), Fengfu to the middle of rear hairline were measured respectively with standard measure instruments, and the proportion relation between bone-length measurement location and the point position were compared.

RESULTSThere was a significant difference between the distance of bilateral Touwei and the distance of the two Wangu (P<0.05). The proportion relation of Shenting-Toulinqi, Shenting-Touwei, bilateral Touwei distances basically conformed to the bone-length measurement location, while in the proportion relation of the distances of Yintang-front hairline, front hairline-Naohu, Naohu-Fengfu, Fengfu-the middle of rear hairline and the bone-length measurement location there were some differences.

CONCLUSIONBilateral Touwei distance is not same as the bone-length measurements between two Mastoid, and Toulinqi can be located at the middle point of the connecting line of Shenting and Touwei. There is a certain deviation between marker location of Naohu, Fengfu and other points on body surface and the bone-length measurements.

Acupuncture Points ; Adolescent ; Adult ; Bone and Bones ; anatomy & histology ; Female ; Head ; anatomy & histology ; Humans ; Male ; Medicine, Chinese Traditional

OBJECTIVEThis study was conducted to determine the three-dimensional structure, course, and adjacent structure of the mandibular incisive canal (MIC) to ensure safety of dental implantation by cone beam CT (CBCT).

METHODSThe CBCT images of the bilateral mandibles of 80 patients were retrospectively studied. The diameters of the mandibular incisive canal and the location in the adjacent structure were determined, including the distances between the MIC and the buccal and lingual plates of the alveolar bone, the inferior border of the mandible and the tooth apex, and the horizontal plane of the mental foramen.

RESULTSApproximately 78.75% (63 cases) of the CBCT scans showed the presence of the MIC with a mean diameter of 1.21 mm +/- 0.29 mm. The distances from the canal to the inferior border of the mandible and to the tooth apex were 7.82 mm +/- 1.86 mm and 7.24 mm +/- 2.82 mm, respectively. The distances between the canal and the buccal plate as well as between the canal and the lingual plate of the alveolar bone were 3.80 mm +/- 1.37 mm and 4.45 mm +/- 1.34 mm, respectively. The distance from the canal to the horizontal plane of the mental foramen was 5.62 mm +/- 2.21 mm.

CONCLUSIONCBCT could clearly show the three-dimensional structure, course, and adjacent structure of the MIC. Therefore, this technique could provide guidance for dental implantation in clinical applications.

Bone and Bones ; Cone-Beam Computed Tomography ; Dental Implants ; Humans ; Mandible ; anatomy & histology ; Maxilla ; Retrospective Studies ; Tongue

OBJECTIVE: To explore the species identification methods of bone remain. METHODS: The compare between human bone and common animals bones was made with microscopic comparison methods. The sample was consisted of 77 slides including human, cattle, house, pig, goat, sheep, monkey, cat, rabbit, chicken, duck, pigeon, tortoise, frog, fish. RESULTS: The differences of the histological bone species were as follow: the thick of the outer and the inner circumferential lamellae, and the shape of interstitial lamellae, and the size of Haversian system, and the number of the circumferential lamellae, and the number of the lacunae of inner Haversian system. CONCLUSION The histological characters of the bones can be used for species identification.
Animals ; Bone and Bones/anatomy & histology* ; Forensic Anthropology/methods* ; Humans ; Species Specificity

OBJECTIVES: To promote the further research on body stature estimation and the innovative applications based on the distances between the anatomical landmarks on body torso surface. METHODS: A specification for the collection of distances between the anatomical landmarks on body torso surface was established. The data of 933 cases of adult population in Yangtze River Delta region were collected. Multiple linear regression method was used to statistical analyse and establish the regression equation of stature estimation. RESULTS: A regression equation about 5 variables including gender （x₁）, cervical vertebrae-coccyx line （x₂）, sterna-pubis line （x₃）, distance between acromion and iliospinale anterius （x₄） and shoulder breadth （x₅）, and stature （y） was established, y=105.406+5.414 x₁+0.436 x₂+0.286 x₃+0.225 x₄+ 0.193 x₅. CONCLUSIONS The method is suitable for the rapid, simple and accurate estimation of stature for the forensic experts.
Adult ; Body Height ; Bone and Bones/anatomy & histology* ; Cervical Vertebrae/anatomy & histology* ; Female ; Forensic Anthropology/methods* ; Humans ; Linear Models ; Male ; Regression Analysis ; Torso/anatomy & histology*

The bone mass and microarchitecture are important determinants of bone strength, with microarchitectural deterioration being one of the specific changes associated with osteoporosis. The purpose of this study was to evaluate and compare the results of microcomputed tomography (micro-CT) and histomorphometry of biopsied specimens. A bone biopsy was performed on the iliac crest of 10 normal premenopausal Korean women. Measurements of the bone mineral density (BMD), micro-CT, and bone histomorphometry were performed. The bone volume, as determined by both micro-CT and histomorphometry, was significantly correlated (r=0.88, p < 0.01). The osteoid surface was correlated with both the bone volume (r=0.84, p < 0.01) and the structure model index (SMI) (r= -0.89, p < 0.01) measured by micro-CT. The SMI was correlated with both the bone volume (r=-0.85, p < 0.01) and the total hip BMD (r=-0.65, p < 0.05). In conclusion, some, but not all of the parameters of the micro-CT, were well correlated with the bone histomorphometric results. Micro-CT and histomorphometry appear to be complementary techniques in the study of bone microarchitecture.
Adult ; Biopsy ; Bone Density ; Bone and Bones/*anatomy & histology/*radiography ; Female ; Human ; Support, Non-U.S. Gov't ; *Tomography, X-Ray Computed

OBJECTIVETo evaluate the effects of alendronate on the structural properties of trabecular bone.

METHODSAlendronate was administered at a daily p.o. dose of 0.5 mg/kg over a 12-week period in hound dogs (n = 8 for both the control and treated group), and the structural indices of the lumbar vertebral (L1 and L2) trabecular bone were assessed directly from 3-D images.

RESULTSTreatment with alendronate increased bone volume fraction by 9.5% and 7.7% in L1 and L2 respectively. Trabecular thickness significantly increased after alendronate treatment, whereas trabecular separation remained constant. The degree of anisotropy for the alendronate-treated group was decreased compared with that of the control group. Bone surface to volume ratio declined significantly in the alendronate-treated group, whereas alendronate induced a higher bone surface density.

CONCLUSIONAlendronate increased the structural properties of canine trabecular bone after short-term treatment at a dose of 0.5 mg x k(-1) x day(-1).

Alendronate ; pharmacology ; Animals ; Anisotropy ; Biometry ; methods ; Bone Density ; Bone and Bones ; anatomy & histology ; drug effects ; Dogs ; Female ; Lumbar Vertebrae ; anatomy & histology ; drug effects