In most cases of chromosomal anomaly of congenital cataract, the cause is known as Down's syndrome. We experienced a case of bilateral congenital cataract in Trisomy 21 (Down's syndrome). A 3 year-old female who had been born from 37 year-old mother was visited to our hospital, with clinical diagnosis of bilateral congenital cataract. Her face was pathognomonic to Down's syndrome. Chromosomal study of peripheral blood showed that the total number of chromosome was 47, and karyotype was 47, XX, +21. The lens showed nuclear opacity. Aspiration and Discission of the cataract on both eyes were performed uneventfully.
Adult ; Cataract* ; Child, Preschool ; Diagnosis ; Down Syndrome* ; Female ; Humans ; Karyotype ; Mothers

Twenty two eyes of twelve infants with threshold or prethreshold retinopathy of prematurity were treated by using the Argon laser through an indirect ophthalmoscopic delivery system. Eyes that had persistent plus disease were retreated to the missed areas. Mean follow-up period was 8.1 months. 20 of 22 eyes were regressed and all of prethreshold ROP were regressed. Our results suggest that argon laser photocoagulation is as effective as cryotherapy in the treatment of ROP and excellent results can be obtained by treating prethreshold zone I or posterior zone II ROP. And laser treatment is better tolerated by infant, accurate, easy, less destructive and not requires general anesthesia.
Anesthesia, General ; Argon* ; Cryotherapy ; Follow-Up Studies ; Humans ; Infant ; Light Coagulation ; Retinopathy of Prematurity*