No abstract available.
Chromosome Deletion*

In order to elucidate the present features of visual-impairments related to refractive errors including myopia and causative factors of myopia among urban school children, visual acuity, refractive components on the myopia, and socioenvironmental factors were examined among 4,004 primary, middle and high school children in Seoul. It was conceived that the results were facilitated for the future improvements of the Eye Health Plan for the school children in this country. This study reveals that visual impairments and prevalence of myopia increase with the school grade(age), and progression of myopia begins earlier in girls than boys. The Progress of myopia is closely related with elongation of ocular axial length along with vitreous A-P length and compensatory reduction of radius of radius of corneal curvature were more apparent in myopia of -0.5 ~ -5.0 D than the group of over -5.0 D. According to the analysis of ancilliary questionnaire, we have got a conclusion that it is statistically significant that the myopization of the ocular structure appeared susceptible with the socio-environmental factors such as eating habits, T.V. watching period and distance, reading hours, distance and type of illumination, and school achievement, which are mainly related to near work. From the results, it is deducible that by improving such environmental factors the myopia in some proportion would be preventable especially in younger children.
Child* ; Eating ; Female ; Humans ; Lighting ; Myopia* ; Prevalence ; Surveys and Questionnaires ; Radius ; Refractive Errors ; Seoul ; Vision Disorders* ; Visual Acuity

From July 1997, Authors have reconstructed the posterior cruciate ligament(PCL) deficient knees with two graft tendons; an autogenous bone-patellar tendon-bone (BPTB) and a semitendinosus tendon. At Femoral side, the two graft tendons were fixed through the two tunnels which were made at the site of foot print of PCL. The original site of anterolateral bundle of the PCL was reconstructe(I with the autogenous BPTB and the original site of posteromedial bundle with the semitendinosus tendon. At tibial side, the two graft tendons were fixed by modified inlay technique; the BPTB was fixed with a cancellous screw and the semitendinosus tendon with staples. Seven cases were followed up more than six months and authors evaluated the results with the KT-1000TM arthrometer and the posterior stress radiographs by Telos stress dcvice and compared the resu]t of injured knee with the uninjured side of each patient. The results of manual maximal displacement test with arthrometer were less than 4 mm in six patients and 8 rnm in one patient at last follow up. The average distance of posterior displacement on stress radiographs was 10.3 mm preoperatively and 2.7 mm at final follow up period. Six of the seven patients had a good stability on posterior stress radiographs compared with the uninjured side. One patient had posterior knee insta- bility on stress radiographs due to loosening of the grafted tendon and retightening of the grafted tendon was performed through the posterior approach to the proximal tibia. The original idea of femoral dual tunnel method in PCL reconstructiori is to reconstruct the PCL more anatomically and the modified tibial inlay technique can solve the problern of graft tendon abrasion at the posterior opening of the tibial tunnel in transtibial tunnel method and retightening of the loose grafted tendon is simple than the other methods of PCL reconstruction. Authors expect that this combined femoral dual tun- nel and modified tibial inlay method may improve the quality of the outcome of the arthroscopic PCL reconstruction.
Arthroscopy ; Follow-Up Studies ; Foot ; Humans ; Inlays* ; Knee ; Posterior Cruciate Ligament* ; Tendons* ; Tibia ; Transplants*

In the case presented a Botulinum toxin was injected into the extraocular muscles to treat limitation of eyeball movement due to retention of a metallic foreign body in the orbit. A 32-year-old man had had a major complaint of exohypotropia with diplopia for 15 years and a routine X-ray examination and C-T scan of the orbit revealed an approximately 5 cm long metallic foreign body bridging the right retrobulbar space, the right ethmoid sinus and the sphenoid sinus. During the course of extracting the foreign body, a lesion on the muscle, fatty tissue and fibrotic adhesion, resulting in disuse atrophy or mechanical damage of the right medial rectus and right superior rectus appeared likely. The injection of 5 units of Botulinum toxin into both the right lateral rectus and the right inferier rectus appeared clinically successful after 6 months, resulting in orthophoria and diminishing diplopia.
Adipose Tissue ; Adult ; Botulinum Toxins* ; Diplopia ; Ethmoid Sinus ; Foreign Bodies ; Humans ; Muscles ; Muscular Disorders, Atrophic ; Orbit* ; Sphenoid Sinus

Twenty cases of blepharospasm and thirty five cases of hemifacial spasm were treated by injection with Botulinum Toxin A during a fifteen-month period. A total of 74 treatment sessions were given for 7 months follow-up period and the mean dose of 17.81 units per lid and brow was administered according to Scott's method. The mean ages of blepharospasm and hemifacial spasm patients were 59 years and 49 years, respectively. The mean response time of toxin against blepharospasm and hemifacial spasm were 159.9 days and 167.1 days respectively. The maximum effect of toxin appeared in the first 1 month period following injection. The mean preinjection spasm grade was +3.17 in blepharospasm, and +2.41 in hemifacial spasm, and mean postinjection spasm grade was +0.88 in blepharospasm and +0.52 in hemifacial spasm. The mean preinjection muscle strength was +3.15 in blepharospasm, and +3.07 in hemifacial spasm, and mean postinjection muscle strength was +1.12 in blepharospasm, and +1.24 in hemifacial spasm. The complications attributed to toxin injection were lagophthalmos, and epiphora. These ocular complications were localized, mild and transient, and no systemic side effects were noted.
Blepharospasm* ; Botulinum Toxins* ; Follow-Up Studies ; Hemifacial Spasm ; Humans ; Lacrimal Apparatus Diseases ; Muscle Strength ; Reaction Time ; Spasm

To evaluate the effect of tibial cut with posterior slope in total knee arthroplasty(TKA) surgery on the flexion of the knee, 41 knees(32 patients) with varying degree of the posterior slope were retrospectively reviewed at more than 1 year after operation. Does sloping the tibial cut iurface rnore posteriorly promote increasing of maximal flexion of the knee by elimination of excessive tenaion of the posterior cruciate liga ment The degree of the posterior slope was radiographically measured, awi the change of the degree of the maximal flexion between preoperative and postoperative period was clinimlly measured with a goniometer at the latest follow up more than 1 year after operation. Comparison of the results demonstrated significantly larger degree of rqaximal flexion for the knees that had tibial cut with the degree of the posterior slope, 5 degrees or rnore (p<0.05). We concluded that 5 degrees or more posterior slope in proxirnal tibial cut is one of the important fact()r which could achieve increased flexion of the knee after TKA operation.
Arthroplasty* ; Follow-Up Studies ; Knee Joint ; Knee* ; Postoperative Period ; Retrospective Studies

Background and Objectives: Endoscopic modified Lothrop procedure (EMLP) is indicated after the failure of standard endoscopic sinus surgery techniques to alleviate frontal sinus disease. Three parameters, such as nasal beak thickness (NBT), accessible dimension of frontal recess (AD), and distance of frontal sinus (DFS), are important in the preoperative evaluation and selection of patients for EMLP. The purpose of this study is to apply the parameters to determine the feasibility of EMLP for the Korean population.Subjects and Method Sinus CT was performed on a total of 233 people, and a study was conducted using 466 bilateral sides with the following parameters: 1) NBT 2) the distance from the posterior margin of nasal beak to the anterior margin of skull base (DNBSB) 3) the right and left AD and 4) the right and left DFS. If the values of NBT, AD, and DFS of the study group were less than 10 mm, greater than 5 mm and 7 mm, respectively, they were considered candidates for the EMLP. Results: DNBSB, NBT, AD, and DFS were 6.97±1.96 mm, 7.01±1.58 mm, 7.16±2.40 mm, and 9.47±2.91 mm, respectively. Parameters except DNBSB showed significant differences in male and female. The feasibility of EMLP was 75.36% for male and 57.89% for female, with 68.24% overall. Conclusion The overall feasibility of EMLP was 68.24% for the study group, where feasibility was lower for female than for male.

Isometric tension was recorded in uterine arterial ring preparation contracted by potassium (60 mM) and norepinephrine(1.8 X 10(-7) M). With pretreatment of various concentrations of nifedipine(2.9 x 10(-9) ~2.9 X10(-7) M) and verapamil(2.2 X 10(-7) -2.2 X 10(-5) M), the relaxation was dose-dependent and inhibitory effects of both agents were more marked on the potassium than norepinephrine-evoked contraction. After immersion of the arterial preparation in calcium-free solution, the potassium-evoked contraction was decreased to 21+/-4.1%(mean+/-SEM) of the response in normal Krebs solution and norepinephrine-evoked contraction to 26+/-3.8%. The responses to both agents were completely restored when the calcium concentration was increased to 4.0 mM. Pretreated nifedipine(2.9 x 10(-7) M) in calcium-free solution depressed the potassium-evoked contraction to 7.3+/-1.6% and norepinephrine-evoked contraction to 12+/-3.7%. In addition of calcium(0-4.0mM), the potassium-evoked contraction increased to 30+/-4.6% and that by norepinephrine to 45+/-5.4%. Pretreated verapamil(2.2 X 10(-5) M) in calcium-free solution depressed the potassium-evoked contraction to 14+/-3.6% and norepinephrine-evoked contraction to 18+/-3.3%. In addition of calcium(0-4.0mM), the potassium-evoked contraction increased to 41+/-4.2% and that by norepinephrine to 57+/-4.7%. It was concluded that nifedipine and verapamil relaxed KC1 contracted ring in the presence of external calcium and relaxed norepinephrine contracted ring in both the presence and absence of external calcium. These findings suggest that calcium antagonists interfere with the release of calcium from intracellular sites as well as with the slow inward current of calcium.
Calcium ; Humans* ; Immersion ; Nifedipine* ; Norepinephrine ; Potassium ; Relaxation ; Uterine Artery* ; Verapamil*

In order to evaluate the distributions of the immunoglobulins in the pterygial tissues, surgically excised pterygia from 18 patients were examined according to PAP staining method to detect the presence of various Ig classes with the control of 5 cases of normal conjunctiva. The PAP staining on the pterygial tissues revealed that the incidence of the positive reactions in 88.7% of IgG, 27.8% of IgA, and 88% of IgE which indicated the noticeable increase in compare with the normal conjunctival tissues. The increased number of IgG, IgA, and IgE in pterygial tissues appeared statistically significant than those of normal conjunctiva(p<0.05). From the evaluation of results, it was attributed that the occurrence of pterygium may result with the immunological processes of inflammatory component. The increase of the IgE in pterygial tissue might also be contributable for the Type I hypersensitivity for the pathogenesis of pterygium.
Conjunctiva ; Humans ; Hypersensitivity, Immediate ; Immunoglobulin A ; Immunoglobulin E ; Immunoglobulin G ; Immunoglobulins ; Incidence ; Pterygium

It was reported that the refractive power in the premature infants was more frequently myopic than in the normal, but there was little known about the onset and pathogenesis. The 106 premature infants, less than 37 weeks's gestational age, were comparatively examined at the age of 4 weeks to determine that there was myopic shift before cicatrical ROP state and the correlation of corneal diameter, axial length with refractive errors. The No-ROP group was 70 infants(140 eyes), and ROP group was 36 infants(72 eyes), and it was possible to analysis statistically only within the 33-36 post-conceptional age because the two groups were not normally distributed. The mean spherical equivalents at the 33-34 weeks were +1.91 Diopter, +1.48 Diopter in the No-ROP group and -0.21 Diopter, 0.00 Diopter in the ROP group, and this was statistically different(p<0.05), but corneal diameter and axial length were not different in both groups(p>0.05). This study revealed that the refractive errors in the ROP group were more myopic shift than in the No-ROP group in regard to early active state of ROP.
Gestational Age ; Humans ; Infant, Newborn ; Infant, Premature ; Refractive Errors* ; Retinopathy of Prematurity