PURPOSE: To investigate the factors associated with glaucoma in patients with pseudoexfoliation syndrome by comparing features of the anterior segments and ocular biometry according to the presence or absence of open-angle glaucoma in pseudoexfoliation syndrome. METHODS: We analyzed 96 patients (115 eyes) diagnosed as having pseudoexfoliation syndrome in this study. The patients were divided into two groups of simple pseudoexfoliation syndrome (64 patients, 76 eyes) and pseudoexfoliation glaucoma (32 patients, 39 eyes). We compared the age, sex, underlying disease, location of pseudoexfoliative material, iris change, degree of nuclear cataract, pupil dilatation, corneal endothelial cell counts, central corneal thickness, anterior chamber depth, axial length, corneal curvature, and intraocular pressure (IOP). RESULTS: There were no significant differences between the two groups in terms of age (p = 0.694), sex (p = 0.161), diabetes (p = 0.440), hypertension (p = 0.238), pseudoexfoliative material observed in anterior capsule (p = 0.700), pupillary margin (p = 0.210), iris depigmentation (p = 0.526), pupillary ruff loss (p = 0.708), degree of nuclear cataract (p = 0.617), pupil dilatation (p = 0.526), central corneal thickness (p = 0.097), anterior chamber depth (p = 0.283), axial length (p = 0.095), or horizontal and vertical corneal curvature (p = 0.066 and 0.306, respectively). In pseudoexfoliation glaucoma, significantly higher IOP (p = 0.026), a high frequency of membrane formation (p = 0.047), and decreased corneal endothelial cell counts (p = 0.048) were observed. CONCLUSIONS: Pseudoexfoliation syndrome with open-angle glaucoma was shown to be associated with high IOP, decreased corneal endothelial cell counts, and a high frequency of membrane formation. Therefore, when such changes are observed in pseudoexfoliation syndrome patients, a higher risk of open-angle glaucoma should be recognized, and careful attentionis required accordingly.
Anterior Chamber ; Biometry ; Cataract ; Dilatation ; Endothelial Cells ; Exfoliation Syndrome ; Glaucoma ; Glaucoma, Open-Angle ; Humans ; Hypertension ; Intraocular Pressure ; Iris ; Membranes ; Pupil

PURPOSE: We report a case of recurrent ocular thelaziasis by Thelazia callipaeda. CASE SUMMARY: A 71-year-old male visited the ophthalmic clinic, complaining of itching, a foreign body sensation, and irritation in the right eye. He was previously diagnosed with Thelazia callipaeda infection, 3 months prior, at another hospital. A parasite, shaped like a thin small thread, was found in the conjunctival sac of his right eye, with active movement. The parasite was identified as Thelazia callipaeda by pathology. Four months after removal of the parasite, symptoms relapsed in the same eye. Two parasites were rediscovered and removed. Since then, no additional specific sign related to the parasite has been noted in follow- up examinations. CONCLUSIONS: Due to frequent recurrence of infections caused by the short life cycle of the parasite, monthly follow-up examinations are required for at least 1 year after discovery of the parasite.
Aged ; Follow-Up Studies ; Foreign Bodies ; Humans ; Lacrimal Apparatus ; Life Cycle Stages ; Male ; Parasites ; Pathology ; Pruritus ; Recurrence ; Sensation ; Thelazioidea