1. DETERMINATION OF THE RISK FACTORS AND TREATMENT OF ECTOPIC PREGNANCY
Ankhgerel J ; Bolortuya B ; Gantulga N ; Enkhtuya M
Innovation 2015;9(3):41-44
Ectopic pregnancy (EP) is a life – threatening emergency, and a significant cause of maternal morbidity and mortality in Ulan – Bator. The aim of this research was to determine and evaluate the incidence, risk factors and treatment of ectopic pregnancies at The First Maternity Hospital in Ulan – Bator.This was a retrospective, descriptive study of EP’s managed in The First Maternity Hospital during the study period 2013, 2014.The medical records of the patients managed for ectopic pregnancy as well as the total birth record and gynecological admission records during the period under review were retrieved, and data were collected with the aid of data-entry forms designed for this purpose. There were 46.147 gynecological admissions and 28.744 deliveries, with 870 cases of ectopic pregnancies. A total 863 cases were suitable for analysis. The relevant collected data were analyzed with SPSS Version 20.0 for windows.Ectopic pregnancies constituted in 3.9% of all gynecological admissions.Majority of patients were in 25-29years age group (64.1%). The average age of patients was 30 +/- 6 years. In 83.8% of patients had previous abortions, inflammatory disease was the most frequent risk factors.521(60.3%) patients were treated surgically while the 342(39.6%) remain patients received conservative treatment.The incidence of ectopic pregnancy increased by 0.8%, which is comparable between 2013(2.5%), 2014(3.3%). In our study the number percentage of organ preserving treatment, such as tubostomy and conservative – treatment by methotrexate increased significantly.
2.Theoretical and methodological issues in human ecogenetics
Diagnosis 2024;110(3):19-24
Human ecogenetics is a broad area of research. It is prioritized in terms of necessity and, in general, is a branch of medicine that studies the unique characteristics of each individual's genetic makeup, adaptation, and response to mutagens.
Approximately 25,000 polymorphic systems are responsible for enzymes, receptors, and elements of human molecular biochemistry. Enzyme systems, transport systems, transport proteins, antigens, and so many variants of receptors cause each individual to respond differently to the effects of chemical metabolism, and physical, and biological factors. The unique characteristics of each individual are the study of human ecogenetics.
Today, elucidating the chemical and physical factors that affect the health of millions of people around the world, and recognizing the interaction between mutagens and the human body, has become the basic direction of scientific research on the one hand, and the main principle of personalized medicine on the other hand.
Ecogenetic research is widely used to solve many theoretical and practical problems. 5% of all newborns in the world are born with congenital malformations. About 30% of all newborn deaths are related to congenital malformations or genetic disorders. Various unfavorable factors of the human ecosystem affect human health, and as this effect is constantly increasing, eco-pathological studies in the field of medicine have been intensively conducted. In recent years scientists, the study of the biological basis of the environment and human interaction based on the integrated ecological-physiological method, including the ecological evaluation and importance of physical, social and technical factors, the study of their combined and separate effects, the structure of human ecogenetic links , the elucidation of individual response characteristics is in full swing.
3. NON-ORGANIC SUBSTANCES IN URINE DURING NEPHROLOGY NEPHROLITHIASIS
Khongorzul B ; Saruul P ; Bolortuya B ; Bolormaa TS ; Urnaa Т ; Bolormaa N ; Erdenetsetseg N ; Shatar SH
Innovation 2015;9(3):170-173
Risk of nephrotith disease increases relating with using high hardened water, not suitable diet, being sensitive for some kind of food products. Then for Mongolia, particularly Bulgan province which is located in basin of the Selenge river is consisted in regions which have high hardened water. Sickness rate of renal diseases especially nephtolith disease is high in population of Selenge soum of Bulgan province. It was main reason of choose this subject and investigate non organic substances in urine of population and determine risks of nephtolith disease for them. To determine оne of the factors affecting the formation of the disease is to study the composition of drinking water and investigate non organic substances in urine. We used cross-sectional methodology for our study. Our study was conducted from June, 2013 to November, 2014. Household water used portable water dissemination and homes with private wells and water samples from the river.Drinking water analyzed of the chemistry parameters (13 substances) in the chemistry and toxicology laboratories in Orkhon aimag. There was 300 urine analyze was done and 62 of them was confirmed nephtolith disease with it. We investigated non-organic substances in their urine. Interviews people in the study, the average age was 43.26±14.7. 64.2% of participants was answered that they use ground water (private groundwater wells), 25.4% use external water (the well water), 8.1% use river water, 2.3 use pure water when asked about their water supply. Composition of samples from drinking water standard was near to the standard assessments by comparing the maximum amount of. We were considered the most important water pH, solids, iron, chlorine analysis compares removable wells and private wells. Hardness for 53.3% of the well of 2.5-3.5 mg/l with hard water, private wells, 60.0% of 4.6-5.5 mg/l solids by of water. Wells chlorides portable 66.7% 14.4-25.3 mg/l, and private wells 13.3% of 4.3-14.3 mg /l. 20.7 percent of survey identified as the kidney and urinary tract diseases. Urat salt (32.1%), compound of urat and sodium (32.1%), oxalate (14.5%), sodium (13.4%), compound of oxalate and sodium (6.4%), phosphate (1.5%) was determined in urine analyze. It was close to the water content of the standard performance. The well water solids of 2.5-3.5 mg/l and private groundwater wells solids of 4.6-5.5 mg/l. And the well chlorides 14.4-25.3 mg/l and private groundwater wells chlorides 4.3-14.3 mg/l.Urat and compound of urat and sodium are dominated in composition of stone during nephrolith disease (p=0.043).