1.Pilot study on metabolic syndrome prevalence among aging male
Bolor-Erdene S, Munkhtsetseg J
Mongolian Medical Sciences 2010;152(2):9-11
INTRODUCTION: Main reasons of metabolic syndrome are obesity and overweighing, which are becoming a global
worldwide problem. Obesity is both a prevalent condition worldwide and a well-known, modifiable risk factor for
various diseases, including diabetes. In a recent review article, waist circumference (WC) and body mass index
(BMI) were reported as established risk factors for diabetes.
GOAL: To define the prevalence of metabolic syndrome among Mongolian aging man living in Ulaanbaatar city
MATERIALS AND METHODS: Randomly selected 180 men aged 35-90 years old were involved to this study. All were
informed and written consent was given by each individual. The metabolic syndrome was defined by NCEP
definition: high blood pressure, high waist circumference, higher fasting sugar, triglyceride and HDL-cholesterol.
Anthropometric parameters like waist circumference (WC), weight, height, blood pressure and blood chemical
parameters like glucose, triglyceride (TG), HDL-cholesterol (HDL-Ch) were measured by automatic biochemical
analyzer.
RESULT AND DISCUSSION: Average age of all participants was 56.82±12.55 years and was divided in three age
groups: 35-60 (n=112), 61-74 (n=47), 74-90 (n=17). The characteristics of participants are shown Mongolian men
in 38.8 % (70) of all participants had a metabolic syndrome and in compare to T.Baysgalan’s study, implemented in
2007 was higher. In our opinion it depends on our study participant’s age, because in our study number of elderly
were predominating than mentioned survey. Waist circumference in metabolic syndrome group is higher than in
healthy control group (p<0.05). Triglyceride level does not change with aging, but in our study participants, the TG
level was negatively correlated with aging in metabolic syndrome group (r = -0.307).
HDL-cholesterol is abundantly circulating molecule in human plasma and shows anti-atherogenic effect. In our
participants HDL-Ch decreases with aging (r=-0.174).
CONCLUSION: Our pilot study present that metabolic syndrome prevalence reaches 38.8% of total aged, male
participants, and it is leads to implement and provide an investigation in large range, including urban and rural
areas of the country.
2.Adiponectin level in aging male of Mongolia
Bolor-Erdene S ; Munkhtsetseg J
Mongolian Medical Sciences 2010;152(2):6-8
INTRODUCTION: Adipose tissue exclusively secretes adiponectin, a 244–amino-acid protein that regulates themetabolism of lipids and glucose and circulates quite abundantly in plasma. Adiponectin were still stronglyassociated with an increased diabetes risk in men; but the association for women was no longer statisticallysignificant. Adiponectin decreases insulin resistance and body weight by increasing lipid oxidation in muscleand other organs such as the pancreas and liver.GOAL: To define of adiponectin level in aging man living in Ulaanbaatar city.MATERIALS AND METHODS: Randomly selected 84 men aged 35-90 years old were involved to this study. Veinblood were collected, the serum were separated and were frozen until assayed by immunosorbent assay.Morning baseline adiponectin were determined in the sera. We used ELISA kit from Mesdia company (Korea).RESULT AND DISCUSSION: Average age of all participants was 56.82±12.55 years and was divided in three agegroups: 35-60 (31.1%), 61-74 (10%), 74-90 (5.55%). Levels of adiponectin were inversely associated with BMI(r=-0.103), WC (r=-0.173), and TG (r=0.143) and directly associated with age and HDL-C (r=0.117, p<0.001).All people were divided by NCEP criteria in two groups: metabolic syndrome group and healthy control group.Average adiponectin level in metabolic syndrome group was 4.83±7.10 ug/ml, in healthy group it was 5.71±7.53ug/ml, which shows that adiponectin level is significantly lower in people with metabolic syndrome.CONCLUSION: Adiponectin level was lower in people with metabolic syndrome and it has inverse correlation withwaist circumference.