1.A collection of Chinese medicinal raw materials and prescriptions in Zorigt wang’s “Mthong ba dga’ byad” sutra and their explanations
Khastana M ; Baolidao ; Tsetsegmaa S ; Bold Sh
Mongolian Pharmacy and Pharmacology 2020;17(2):54-58
Abstract:
In addition to citing from the old medical scriptures by Indian, Tibetan, and Mongolian medical scholars, “Mthong ba dga’ byad” by Jigmeddanzanjamts, also contains a number of prescriptions of Chinese medicine that were widely used in Chinese medical practice at that time. Therefore, crude drugs and prescriptions of Chinese medicine in this book has a great significance, but there are few studies done in the last decades.
Purpose:
To make selection of Chinese herbal medicines and recipes from the book “Mthong ba dga’ byad” by Jigmeddanzanjamts and explain them.
Research methods:
Research methods in ancient textbook, check list, analysis and synthesis methods were used.
Conclusion
It was clarified that in the book “Mthong ba dga’ byad” by Jigmeddanzanjamts there are 44 names of herbal medicines and prescriptions of Chinese origin, and some prescriptions are explained. According to these herbal medicines and prescriptions, Mongolian doctors and maarambas used not only Indian Ayurvedic and Tibetan medicines, but also Chinese medicines and prescriptions in their medical care.
2.Immunohistochemical study of cervical lymph node metastases of unknown primary origin
Enkhee O ; Tuul B ; Bold M ; Bulgan P ; Ulambayar E ; Odkhuu J ; Bayarmaa E
Mongolian Medical Sciences 2013;166(4):21-26
Introduction. Cancer of unknown primary (CUP) is histologically defined as the presence of a metastasis of lymph node without detection of the primary tumor [1]. Approximately 3–15% of all cancers are designated as CUP [3. 4]. The diagnosis, treatment and monitoring of patients with laterocervical metastases of unknown primary involves a wide range of oncologic entities [5]. While we were studying patho-histological examination of cervical lymphadenopathy in Mongolian, werevealed unknown primary tumor. This is a goal of our study. Objectives of study are followings to differentiate whether primary lymphoma or metastatic cancer of cervical lymph node metastasis of unknown primary tumor and to reveal primitive origin of tumor using by basic and additional immunohistochemical markers.Goal.To determine the conclusive diagnosis in cervical lymph node metastasis of unknown primary origin by immunohistochemical techniqueMaterials and Methods. In this study, we examined immunohistochemically 30 cases of outpatient head and neck surgical unit of the National Cancer Center and dentistry and oral maxillofacial surgical unit of the State Central Hospital which were diagnosed as cervical lymphadenopathy. For immunohistochemical study, we applied an immunohistochemical panel in accordance with avidinbiotin- peroxidase complex method and used a basic and additional antibodies represented by CK(pancytokeratin), LCA, synaptophysin, chromogranin and HMB45. Result. In our study, there was 63.3% lymphoma, 36.7% metastatic cancer. Among them, there were 4 of digestive tract adenocarcinoma, 3 of squamous cell carcinoma /2-esophagus, 1-nasopharyngeal/, 2 of neuroendocrine tumor and 1 of melanoma.Distribution by age groups shows that 20-29 years were 4(13.3%), 30-39 years were 10 (33.3%), 40-49 years were 8 (26.7%), 50-59 years were 3 (10%), over60 years were 5 (16.7%). Gender distribution showed an increased incidence of males (56.7%, 17 cases) compared with females (43.3%, 13 cases).Conclusion: In our study, B cell lymphoma and digestive tract adenocarcinoma were the most common. In further, it is necessary to introduce an immunohistochemical method in patho-histological practice.
3.Clarification of ancient works written by foreign researchers on mongolian pharmacology and pharmaceutical formulation
Khastana M ; Gerelmaa B ; Chimedragchaa Ch ; Bold Sh
Mongolian Pharmacy and Pharmacology 2020;17(2):49-53
Abstract:
In recent years, the study of pharmacology and pharmaceutical formulation of traditional Mongolian medicine has been developing significantly. However, there are few research papers on Mongolian pharmacology and development of pharmaceutical formulation written by foreign researchers in ancient times. Therefore, the study was carried out to fill this “gap” and to clarify the ancient works of foreign researchers related to Mongolian pharmacology and development of pharmaceutical formulation.
Purpose of the study:
To chronologically identify the early works of foreign researchers on the study of pharmacology and pharmaceutical formulation of traditional Mongolian medicine.
Research method:
Hermeneutic approach, analysis of ancient textbook, and analysis and synthesis methods were used.
Conclusion
According to facts and eyewitnesses in the book of Zhouhou Beijifang (Emer- gency Prescriptions) by Ge Hong (261-341) of the Jin Dynasty, Jingui Yaolüe (Essential Prescriptions from the Golden Cabinet) by Chang Ji, the Northern Han Dynasty’s notes on “Xiongnu Doctors Carry Toxic Drugs”, Jāmiʿ al-Tawārīkh (Compendium of Chronicles) by Rashid-ad-Din, William de Rubruck’s “Journey to the Orient”, and book of Plano Carpini, an Italian tourist, the development of pharmacology and pharmaceuticals in traditional Mongolian medicine dates back to the Xiongnu period. Later, in the fourteenth century, it became an independent system of medical knowledge of many nations, as evidenced by the writings of Chinese, Persian, French, and Italian scholars as well as religious envoys.
4.Identifying the specialty and number of animal-oriented medicines in the “Mdzes mtshar mig rgyan” sutra
Sumyakhorol G ; Sumyatseren B ; Shinegerel M ; Bold Sh
Mongolian Pharmacy and Pharmacology 2021;19(2):47-52
Introduction:
More than 30 years have passed since the revived and developed of traditional medicine, and dozens of textbooks and publications on traditional medicine have been published and qualified personnel have been trained. However, there is a need to drastically improve the quality of traditional medical care and the knowledge and skills of doctors. Therefore, it is important to translate, study books written by ancient physicians, maaramba, and scholars, and to apply theory, diagnosis, and treatment methods in training and practice.
Research materials and methods:
Basic research materials: Naiman toin Jambaldorj (1792-1855). གསོ་བྱེད་མཛས་མཚར་ མིག་རྒྱན། Tibetan scripture of a wooden printing block.
Method:
We used germenevtic method and checklist method.
Result:
In the frame of this research, we used the medical sutra written by Jambaldorj as the main material in order to clarify the specialty and number of animal-oriented medicines in the “mdzes mtshar mig rgyan”. During the research, it was possible to clarify the structure, general content, and specialty of the sutra written by Jambaldorj, classify animal-oriented medicines according to the cyrillic alphabet, and make allegory names for some of the raw materials of animal origin. In addition, the study of animal-oriented medicines in the sutra showed that many issues were important, such as their identification, usages, and new production. As a result of the first study, we identified the characteristics and usages of some essential animal-oriented medicines.
Conclusion
Jambaldorj began writing the “mdzes mtshar mig rgyan” before leaving for Tibet, and later, during his pilgrimage to Tibet, he enriched and completed it in his book. It was found to correspond to the period 1817-1823. A selection of 124 animal-oriented medicines from the book “mdzes mtshar mig rgyan” was made. In this way, it is possible to interpret and explain the hidden meanings of animal-oriented medicines in this sutra, and to determine the usages of pharmacology and drug formulations.
5.An analysis of the anti-cold medicine in the khamba nomun khan’s “Man ngag bdud rtsi zegs ma” sutra
Sumiyatseren B ; Shinegerel M ; Sumiyakhorol G ; Ulaan-Od H ; Bold Sh
Mongolian Pharmacy and Pharmacology 2021;19(2):53-57
Introduction:
Luvsandanzanjantsan has written a total of 4 volumes, 79 collections and 220 classes in Tibetan, including 5 medical books. Luvsandanzanjantsan’s “man ngag bdud rtsi zegs ma” sutra, which was the main research material for our study. We made it easier to start studying the “Root Tantra” of the “Four Medical Tantras”, a classic work of Indian and Tibetan medicine. “Four Medical Tantras” was the main guide for medical students of traditional medicine at that time. The book “man ngag bdud rtsi zegs ma” has 18 pages sutra from the many works written by Khamba Nomun Khan. He summarized his experience and lessons learned in differential treatment of fever, some of the most common diseases in women, medical care for 22 diseases such as wind, bile and phlegm, measles, mumps, gonorrhea, edema, cold, and so on. We have studied the medicine treatment of colds from these treatments.
Purpose:
Explain the meaning of the use of anti-cold medicine in the “man ngag bdud rtsi zegs ma” sutra by Lama Gegeen Luvsandanzanjantsan.
Methods:
Methods of textual analysis for ancient books and analysis and synthesis were used in the study.
Conclusion
Luvsandanzanjantsan was not only a famous scientist who penetrated in many fields of knowledge, but also expanded the research work of Mongolian medicine and became the first Mongolian doctor to study medicine in outer Mongolia. There are three parts in the “man ngag bdud rtsi zegs ma” sutra by Lama Gegeen Luvsandanzanjantsan. For treatment to the anti-cold, Mana-4 tan and Norov-7 tan are used in preliminary stage, Tuglogunsel, Tushmel-3, Gajid-9, Erkhem-8, Gurgem-7, Rinchenshagba and Uvsun em-11 are used in hot stage.
6.The issue of clarifying the content of the Lama gegeen’s biography and the “Gsal ba’i sgron me” sutra
Shinegerel M ; Sumyatseren B ; Sumyakhorol G ; Hulangaa A ; Bold Sh
Mongolian Pharmacy and Pharmacology 2021;19(2):58-62
Introduction:
The basis of the development of traditional Mongolian medicine in the 21st century is the importance of reading and studying the biographies of previous generations of ancient doctors and scientists, as well as old medical books and sutras. For example, it is important to gain a deeper understanding of the scientific basis of the ancient medical books, and to understand the manuals and treatment’s methods of doctors and maarambas.
Research goal:
Studying the biography of Erdene Bandida Khutagt, Khamba Nomuun Khan Hanchen Choijal Luvsandanzanjantsan, and his medical book titled “gsal ba’i sgron me”.
Research methods:
We used following study methods; manuscripts, primary source methods, hermeneutic method, matrifocal listing method, historical comparative method and analysis synthesis method.
Result:
Erdene Bandida Khutagt, Khamba Nomuun Khan Hanchen Choijal Luvsandanzanjantsan, the first incarnation of the Lama Gegeen, was born on the 15th of January 1639, in Ulziit Ovoo, Sain Noyon Khan aimag. In 1643, at the age of five, he was initiated by Namkhaisodnomdagva and named Choijidorj. In 1644, at the age of six, he went to Tibet in order to study Tibetan script, calligraphy, and secret tantric rituals and other subjects including medicine taught by Luvsanyarpel, who came to Mongolia from the Dashlkhumbe Monastery of Tibet. Thus, from an early age, he was immersed in religious and medical teachings. Luvsandanzanjantsan has written five books in Tibetan. We selected the book titled “mkhan chen chos kyi rgyal poi gsung ‘bum las gso ba rig pa’i rtsa rgyud kyi’ grel pa gsal ba’i sgron me ces bya ba bzhugs so” as our main subject of study. The book clearly explains the “Root Tantra” of the “Four Medical Tantras”, clarifies the difficult words and content of the theory and makes it easier for people to learn. In addition, we have studied the structure, content, and concluding remarks of this book.
Conclusion
Luvsandanzanjantsan was not only a scientist who penetrated the five great sciences, but also made a valuable contribution to the expansion of Mongolian medical research field and the introduction of Tibetan medicine into Mongolia. He is credited with reviewing and commenting on the best medical works of Indian and Tibetan scholars.
7.Analyzing additional methods of the prescription in the “Man ngag bdud rtsi zegs ma” written by khamba Nomun Khan Luvsandanzanjantsan
Khastana M ; Pingcuodajie ; Sumiyatseren B ; Ulaan-Od H ; Bold Sh
Mongolian Pharmacy and Pharmacology 2022;20(1):86-90
Abstract:
Mongolian traditional medicine is an enormous knowledge that has been battling with long term diseases of Mongolian ancestors by gaining experience, analyzing and learning from foreign medicinal theory and practice for 5000 years. Throughout this long historic evolution Mongolian scholars have published many writings about diagnosis, treatment, medicines and ingredients and among these arised Mongolian traditional medicine theory and practice.
The development basis of XXI century traditional medicine are the books and writings of previous doctors, scientists’ knowledge and search through them in depth about practice, medicine especially ingredients and their correlation backgrounds are essential.
Purpose:
Analyzing additional methods of the prescription included in the “man ngag bdud rtsi zegs ma” written by Khamba Nomun Khan Luvsandanzanjantsan
Methods:
Methods of check list, textual analysis for ancient books and analysis and synthesis were used in the study.
Conclusion
There ara 47 prescription for the addition medicine included in the “man ngag bdud rtsi zegs ma” written by Khamba Nomun Khan Luvsandanzanjantsan. We classified them into 4 categories as supporting medicine, ruling medicine, changed medicine and dominant medicine.
The supporting medicines were chosen by doctors’ knowledge and practice. Ruling medicine ingredients are used to elevate the effects on the cause, nature and symptoms of the disease, changed medicine ingredients are used to treat three humors’s disorders and dominant medicine ingredients are used to treat complications.
8. EPIDEMIOLOGIC STUDY OF ORAL AND MAXILLOFACIAL SURGERY PATIENTS IN MONGOLIA
Davaadorj P ; Otgonbileg E ; Bold M ; Odkhuu J ; Purevdorj G ; Denis S ; Ayanga G ; Khuderchuluun CH ; Batbayar B ; Baasanjav N ; Oyunaa CH ; Budmaa S ; Khentii L
Innovation 2015;9(Dentistry):16-20
The purpose of this study was to analyze the epidemiology of oral and maxillofacial surgery patients in Mongolia and advocate guidelines and programs to promote optimal oral health care. A fact-finding epidemiologic study on the patients who visited at Departments of Oral and Maxillofacial Surgery, at National Hospitals at Ulaanbaatar city and Province and other Central hospitals of Mongolian, from Jan to Dec, 2013.Total 12957 patients treated at inpatients care center at the above mentioned national hospitals. From Ulaanbaatar city were 4284 (36%) and from province were 7673 (64%). Patients from province were treated at FCH 69%, NTORC 6.4%, NCC 11.3%, NCMCH 27% and CMAFH 1.8%. Zero to 16 years, 17 to 36 years, 37 to 56 years and 57 or more years old patients were3072 (27.1%), 4224 (34.2%), 3218 (26.9%) and 1412 (11.8%), respectively. Males and females were 6841 (53%), 6090 (47%). Cases of the inpatients were as follows: infectious disease 5971 (49.88), benign tumor 1039 (8.01%), trauma & injury 1799 (15%), salivary gland disease 2.41%, TMJ disease 2.8%, neuralgia and muscle pain 0.8% and others. 5 provinces have no Oral and Maxillofacial Surgeon and patients were referred to other central hospitals or to the Ulaanbaatar city. This study gives a topic of conversation about undergraduate dental education, continuing education and enough specialists in the region.
9.Comparison study of number of bones in human body of traditional and modern medicine
Tudevdagva L ; Bold Sh ; Tuul Kh ; Ariunjargal T ; Bat-Ochir M ; Bazarragchaa S ; Enkhjin G ; Duutbayr Kh
Mongolian Pharmacy and Pharmacology 2021;18(1):11-16
Background:
During the historical development of traditional medicine, many books and manuscripts have been written in Mongolian medicine. The main textbook of traditional medicine states that: “The size of a bone consists of 23 bone species, 28 spinal joints, 24 ribs, 32 teeth, and 360 pieces of bone.”
However, modern medicine estimates that the human body has 206 bones. Therefore, this topic was chosen to study the source material of traditional medicine, including the structure of the human body, and the number of bones in the modern medical anatomy textbook.
Purpose:
Details of the number of bones in the human body in the “Four Medical Tantras”
(རྒྱུད་བཞི) of traditional medicine and its commentary, as well as compare with the number of bones in the basic textbook of anatomy of modern medicine.
Objectives:
In order to successfully implement the research objectives, the following objectives will be implemented. These include:
1. Sampling and analyzing number of bones from traditional medicine;
2. Sampling and analyzing bone numbers from modern medical textbooks;
3. Compare the names and numbers of bones in traditional medicine and modern medicine
Results:
The number, classification and features of human bones were analyzed from the main scriptures of traditional medicine such as “Explanatory Tantra”, of the “Four Medical Tantras” and the “Legs bshad gser gyi thur ma” by Blo-bzang-chos-grags. In addition, the number of bones in the human body was sampled from modern medical textbooks and prepared for comparison. The number and characteristics of bones in the human body were compared by traditional medicine and modern medicine and made a conclusion.
This study reveals that the foundations for the integrated development of traditional medicine were laid long ago in Mongolian medicine. In addition, to highlight the book “Four Medical Tantras”, which is the basis of the textbook on the structure of the human body and the research work of scientists and scholars, which is considered in Mongolian mamba datsan’s contribution to the science of human anatomy. The importance of this research is to change the extremes of Western medicine and traditional medicine and increase opportunities to use its introduction and development into training and clinical practice.
Conclusion
1. The main creature of body structure in traditional medicine is the “Four Medical Tantras” which generally assumes that the numbers of bones are 360 but does not specify it in detail. During the research, we identified 357 bone names to identify each bone. The names and locations of the three bones were not clearly marked in the medical sources.
2. The numbers of bones are 206 in modern medical textbooks. We recalculated 151 bones based on traditional medical sources without duplication of that.
3. Compared to traditional medicine and modern medicine, the number of bones and are higher than 154 bone names in traditional medicine because we included the number of teeth, small bones in the ears and small bones in the fingers and toes. Some cartilage was also counted as bones.
10.PREVALENCE AND PATTERN OF MANDIBULAR FRACTURE
Bulgantamir E ; Bold M ; Bulgan P ; Ulambayar E ; Bayarmonkh G ; Davaadorj P
Innovation 2017;3(1):20-22
BACKGROUND
The occurrence of facial injuries tends to be high compared to injuries in other parts of the body,
because the face is without a protective covering, and the chin mandible is the most prominent bone
in this region of the body. According to several studies, mandibular fractures account for 59% of all
facial fractures. Mandibular fractures usually occur in 2 or more locations because of the bone’s U
shape. This article aims to analyze retrospectively the age, gender, etiology, and anatomic distribution
of mandibular fractures.
METHODS
The data for this study were obtained from the medical records of 1217 cases treated at Department
of Oral and Maxillacial Surgery at National First Central Hospital of Mongolia in 2016. Information was
collected from the clinical notes of each patients with mandible fractures. The demographic variables
such as age, gender and clinical information included diagnosis, etiology, and anatomical distribution
of fractures was assessed.
RESULTS
The total of 229 subjects had mandible fractures, out of which 209 were males and 20 were females.
The mean age of the participants was 32,2±10. The major cause of fractures was assault 79% ,
followed by road traffic accident – 11%, sport injuries – 5%, accidents at work or home – 3%, other –
2%. Mandible fracture incidence were high during in August. By the time referred to a physician from
day of injury were 1-5 days 72,1%, 6-10 days 25,7%, delayed more than 10 days were 2,2% of the
cases. Unilateral fractures were 77,4%, bilateral fractures 21,7%. Mandible left side were 158 (65,9%)
mostly injured. The most common fracture site was angle- 112 (53%), condyle- 58 (27,5%), body- 21
(9,9%), parasymphysis- 16 (7,6%) and at least common site were ramus- 2 (1%) and symphysis - 2 (1%)
of mandible. Among multiple fractures most common sites were condyle-parasymphysis which 24
cases and angle – parasymphysis were 21 cases.
CONCLUSION
The following conclusions have been drawn from the foregoing study.
The mandible fractures were more common in males 209 (91,3%) than females 20 (8.7%). Assaults
were the most common cause of the fracture. 77,4% fractures were unilateral fractures. The most
common site of fracture was mandible angle- 112 (53%) and common multiple fractures were
condyle-parasymphysis. By the time referred to a physician from day of injury were 1-5 days 72,1%,
6-10 days 25,7%, delayed more than 10 days were 2,2% of the cases.