No abstract available.
Goiter*

No abstract available.
Ectoderm* ; Ectodermal Dysplasia*

OBJECTIVES: We compared the characteristics of the pain threshold and pain experience between demented group and non-demented group. METHODS: This study was part of Gangwon projects for early detection of dementia in 2010. We recruited 8302 local resident ages over 65 years old. Of theses, 1259 people who scored low MMSE were selected and 365 of them completed CERAD-K(Consortium to Establish a Registry for Alzheimer's disease). Finally, 90 in non-demented group and 57 in demented group(mild to moderate Alzheimer's disease) were analyzed. Pain threshold was experimentally measured by pressure algometer and we investigated the pain experience, by Brief pain inventory (BPI), a self-report test. RESULTS: In the demographic characteristics, there are more female, higher ages, lower education in the demented group. There was no significant difference between the two groups in the pain threshold. On the BPI results, 'shoulder pain', 'the number of pain' and 'interference of working' were significantly more prevalent in non-demented group. However, there are no significant differences between the groups in the 'pain severity', 'prevalence of pain' and 'pain treatment'. CONCLUSIONS: Demented group report less pain experience but, still perceived pain. It support previous studies that patient with dementia have increased pain tolerance but preserved pain threshold. Thus, active pain assessment and treatment for patients with dementia is needed.
Aged* ; Dementia* ; Education ; Female ; Gangwon-do ; Humans ; Pain Measurement ; Pain Threshold*

No abstract available.
Humans ; Infant* ; Mothers* ; Polyhydramnios

PURPOSE: To determine if korean normative database improve diagnostic ability of Stratus OCT for detection of glaucoma. METHODS: Peripapillary retinal nerve fiber layer (RNFL) and optic nerve head regions were measured using a Stratus OCT. The normative data were collected from 129 normal individuals. We obtained values at the 5% and 1% levels according to the disc area stratified into equal thirds to minimize the error by the individual variation of optic disc size and these levels were considered abnormal. One eye of each 94 normal-tension glaucoma patients with early visual field defects (mean deviaton = -3.84+/-1.40dB) and 87 another normal subjects were enrolled. Glaucoma was defined by visual field defects. RESULTS: The use of Korean normative database had higher sensitivity and no significant difference of specificity than that of a Stratus OCT except for a few parameters. The criteria that show the highest diagnostic ability were 1 > or = quadrants RNFL thickness abnormal at the < 5% when using a Korean normative database (sensitivity = 81.9%, specificity = 81.6%) and 1 > or = clock hours abnormal at the < 5% when using a Stratus OCT normative database (sensitivity = 71.3%, specificity = 87.4%) (p=0.004, p=0.180, respectively, McNemar test). CONCLUSIONS: The criterion using a Korean normative database had higher sensitivity and no difference of specificity compared with criterion using a Stratus OCT normative database. The best criterion using a Korean normative database may be helpful for early detection of normal-tension glaucoma.
Eye ; Glaucoma ; Humans ; Nerve Fibers ; Optic Disk ; Optic Nerve ; Retinaldehyde ; Sensitivity and Specificity ; Tomography, Optical Coherence ; Visual Fields

PURPOSE: The platelet number alone does not give a complete picture of platelet maturity and function, therefore, the platelet indices have been the subject of intensive study in recent years, but they have not been firmly established in the neonates. METHODS: Blood samples collected in K2 EDTA bottle from femoral vein of 176 neonates (54 healthy fullterm, 96 sick fullterm, 10 sick preterm, 9 healthy preterm and 7 healthy small for gestational age) were analyzed with CELL-DYN 1600. RESULTS: 1) Platelet counts (PC) and platelet indices of 70 healthy neonates correlated neither with gestational age, nor with birth weight. 2) Significant correlations were found between PC and plateletcrit and between PC and mean platelet volume with the correlation coefficients being 0.937 and -0.284 respectively. Other indices did not show any significant correlation. 3) There were no significant differences of PC and platelet indices between healthy neonates and sick neonates, between healthy fullterm and sick fullterm, between healthy preterm and sick preterm, between healthy fullterm and healthy preterm, and between healthy fullterm and healthy small for gestational age. 4) Sick fullterm neonates suffering certain diseases showed altered indices, compared with healthy fullterm neonates. In diarrhea, PC, plateletcrit and platelet distribution width were higher than those in healthy fullterm neonates. In hyperbilirubinemia and urinary tract infection, PC and plateletcrit were higher, whereas in sepsis, platelet distribution width was lower. CONCLUSIONS: These data indicate that PC and platelet indices of healthy neonates did not correlate with gestational age, nor with birth weight, and show some significant correlations between PC and platelet indicies. Further studies will be needed in clinical application of platelet indices to each neonatal disease.
Birth Weight ; Blood Platelets* ; Diarrhea ; Edetic Acid ; Femoral Vein ; Gestational Age ; Humans ; Hyperbilirubinemia ; Infant, Newborn* ; Mean Platelet Volume ; Platelet Count* ; Sepsis ; Urinary Tract Infections

Norwegian, or crusted scabies, is a fulminant and highly infectious form of scabies in which a large number of Sarcoptes scabiei mites infest the epidermis. This is often seen in the physically or mentally handicapped, immunocompromised, and institutionalized persons. The characteristic skin lesions in this form are gross scaling and hyperkeratotic plaques with erythematous papules, especially on hands, feet, elbow, and subungual area with varying degrees of pruritus. It may be difficult to differentiate Norwegian scabies from tinea unguium when Norwegian scabies involves nail and subungual area. We report a case of tinea unguium hidden by Norwegian scabies with nail involvement in a 71-year-old patient. This is the first report of such a case in Korea.
Aged ; Elbow ; Epidermis ; Foot ; Hand ; Humans ; Institutionalization ; Korea ; Mentally Disabled Persons ; Mites ; Nails ; Onychomycosis ; Pruritus ; Sarcoptes scabiei ; Scabies ; Skin ; Tinea

A 38-year-old man, with recurrent oral ulcers for 10 years, was admitted because of recent aggravation of odynophagia and sore throat. About 4 years earlier, he had been performed abdominal surgery for intestinal perforation. Gastrofiberscopic examination showed small round ulcers at hypiopharynx and 6cm sized longitudinal linear ulcer at mid esophagus. Biopsy specimens at mid-esophagus showed chronic inflammation. Besides oral ulcer, he had perianal ulcers and skin rashes. He was managed with steroid, colchicine and sulfasalazine under the diagnosis of esophageal involvement in Behcet's disease. After 3 months from discharge, esophagogram and gastrofiberscopic examination showed some improved appearance, but symptoms recurred for steroid tapering. He has been followed in much improved status for 8 months after discharge.
Adult ; Biopsy ; Colchicine ; Diagnosis ; Esophagus ; Exanthema ; Humans ; Inflammation ; Intestinal Perforation ; Oral Ulcer ; Pharyngitis ; Sulfasalazine ; Ulcer*

Retinoblastoma is a rare, congenital, malignant tumor that arises from the retina. It is the most common intraocular tumor occurring during childhood. Retinoblastoma usually remains unnoticed until it has advanced far enough to produce a white pupil. But it may manifest as a painful, red, tearing eye due to secondary glaucoma. The most common mechanism inducing secondary glaucoma in retinoblastoma is neovascularization of iris with peripheral anterior synechiae formation. The next common mechanism is massive exudative retinal detachment causing pupillary block and angle closure. Uveitis and/or necrotic tumor tissue in anterior chamber acn contribute to the development of secondary glaucoma. A 9 month old Korean boy was seen to have somewhat enlarged cornea with massive exudation in anterior chamber OS. Intraocular pressure was 27.4 mmHg OS. The C-T scan was done because of hazy media OS. and showed calcification within left eye. Left eye was enucleated and found to have retinoblastoma which was confirmed microscopically.
Anterior Chamber ; Cornea ; Glaucoma* ; Humans ; Infant ; Intraocular Pressure ; Iris ; Male ; Pupil ; Retina ; Retinal Detachment ; Retinoblastoma* ; Tears ; Uveitis

Renal cell carcinoma takes up 85 per cent of primary malignant renal tumors. It frequently metastasizes to the adrenal gland, lung, bone, liver and nephrectomy site but rarely to the head and neck area. When metastasizes to head and neck area, it involves the gingiva, tongue, palate, parotid gland, uvula, mandible, and lip. When tumors are found in the salivary gland consisting of clear cells, it is impartant to carry out differential diagnosis of various primary tumors with clear cell and metastatic renal cell carcinoma. Patients' medical history, review of system, and pathologic findings would be helpful factors in the differential diagnosis. In this paper, we report on a case of renal cell carcinoma which had metastasized to the psubmandibular gland after a radical nephrectomy.
Adrenal Glands ; Carcinoma, Renal Cell* ; Diagnosis, Differential ; Gingiva ; Head ; Lip ; Liver ; Lung ; Mandible ; Neck ; Nephrectomy ; Palate ; Parotid Gland ; Salivary Glands ; Submandibular Gland* ; Tongue ; Uvula