1.Principle and application of air disinfect-purifying machine in ICU
Chinese Medical Equipment Journal 1989;0(04):-
Objective To properly choose and employ an air disinfect-purifying machine in ICU. Method This paper analyses the principle of air disinfect-purifying machine and put forward some attention-deserved problems such as the value of CADR in clinical application. Conclusion. The disinfect-purifying machine with different CADR value should be chosen according to the area of air disinfect-purifying district, thus can really bring the machine into full play.
2.Primary cutaneous diffuse large B-cell lymphoma, leg type: report of a case.
Xiao-yu LU ; Chen LU ; Yu-lei YIN ; Bo YU
Chinese Journal of Pathology 2010;39(6):416-417
Antigens, CD20
;
metabolism
;
Antineoplastic Combined Chemotherapy Protocols
;
therapeutic use
;
Diagnosis, Differential
;
Humans
;
Leg
;
Lymphoma, Follicular
;
metabolism
;
pathology
;
Lymphoma, Large B-Cell, Diffuse
;
drug therapy
;
metabolism
;
pathology
;
Male
;
Middle Aged
;
Neoplasm Recurrence, Local
;
Skin Neoplasms
;
drug therapy
;
metabolism
;
pathology
3.Effects of autologous bone marrow mononuclear cells transplantation on the cardiac function of dilated cardiomyopathy patients
Yanjun CHEN ; Yao ZHANG ; Bo YU
Chinese Journal of Practical Internal Medicine 2006;0(24):-
0.05).Conclusion Intracoronary transplantation of ABMMNCs may not improve the heart function of DCM with abnormal Q wave.
4.Changes of Activated T Cell Disfunction in Children with Refractory Mycoplasma Pneumoniae Pneumonia
yong, YANG ; yu, WANG ; zong-bo, CHEN
Journal of Applied Clinical Pediatrics 2006;0(20):-
Objective To study disfunction of activated T cell from peripheral blood and explore its role on pathogenesis in patients with refractory mycoplasma pneumoniae pneumonia (MPP).Methods T cell subsets and expression of membrane molecule on activated T cell in peripheral blood were measured in 26 refractory MPP patients by using immunofluorescence and flowcytometry,and compared with those of 18 control healthy children.Results The percentage of CD4~+ cell from peripheral blood in refractory MPP children was significantly lower than that in control group(P0.05).Conclusions There are disfunctions of T cell in refractory MPP patients in acute period,and the abnormal T cell activated disfunction may play an important role on pathogenesis.
5.Progress in Application of Soft Tissue Taping Techniques for Ankle Sprains (review)
Song CHAI ; Bo YU ; Wenhua CHEN
Chinese Journal of Rehabilitation Theory and Practice 2015;21(3):284-287
The ankle sprain is very common in clinic. It will be sprained again if it is not handled properly, and even develop into chronic ankle instability which will affect people's daily life and exercise. This paper discussed the soft tissue techniques, especially kinesio taping, applied for ankle sprain in clinical. As a non-invasive therapy, soft tissue taping can relieve the symptoms of ankle sprains, stable ankle, improve ankle function and prevent recurrent ankle sprain, which is worthy of further research and application.
6.Application of Recreational Therapy in Stroke Rehabilitation (review)
Yunyu ZHU ; Wenhua CHEN ; Bo YU ; Yanyan YU ; Qi WI
Chinese Journal of Rehabilitation Theory and Practice 2009;15(2):152-154
Stroke patients usually are complicated with degeneration of body function as well as emotional and cognitive problems; consequently it will affect capacities of daily lives and recreation in most cases. Recreational therapy (RT) being favorable as far as stroke rehabilitation is concerned. The authors reviewed current developments of applications of RT to carry on a brief talk about present and future utilization of RT in stroke rehabilitation and it holds the point that when practicing RT we should introduce relevant evaluation Methods and techniques adopted in physical therapy (PT) and occupational therapy (OT) area into comprehensive rehabilitation program for some better Results . Evidence based principal should also play a positive role to make a systematic and specific intervention plan in further procedure of RT treating stroke patients.
7.Clinicopathologic study of processing completely embedded radical prostatectomy specimens
Li XIAO ; Yulei YIN ; Yan CHEN ; Chen LU ; Bo YU
Chinese Journal of Clinical and Experimental Pathology 2014;(11):1251-1255
Purpose To study clinicopathologic feature of prostate cancer by complete embedding of radical prostatectomy specimen. Methods 108 cases of radical prostatectomy by systematic whole organ embedding were reviewed. Results The patient age ranged from 55 to 80 years ( mean 68. 1 years) . The preoperative average PSA value was 18. 3μg/ml. 59 cases ( accounting for 54. 6% of all prostatectomy cases) were in pT2 stage, while 23. 7% (14/59) in pT2a stage, 8. 5% (5/59) in pT2b, and 67. 8% (40/59) in pT2c. 49 cases (45. 4%)in pT3 stage, while 59. 2% (29/49) in pT3a, 40. 8% (20/49) in pT3b. 3. 6%(3/84)cases presented pelvic lymph node metastasis. 8. 3% (9/108) cases were graded as Gleason Score 6 or less, 61. 1% Gleason Score 7, 30. 6%(33/108)Gleason Score 8 or more. Gleason Pattern 5 component was found in 26. 9% (29/108) cases. Positive margin was observed in 25. 9% (28/108) cases, with 75% (21/28) in pT3 stage and 53. 6% (15/28) having Gleason Pattern 5. Patient in pT2 stage pres-ented mean PSA value of 14. 00 μg/ml, involved in no more than 2 biopsy cores in 68. 5% cases, and more than 5 cores in 4. 3%, while in pT3 stage, presented mean PSA value of 23. 82μg/ml, involved in no more than 2 cores in 19. 6%, and more than 5 cores in 28. 3%. The difference of involved core number was significant in pT2 and pT3 tumors ( P<0. 01 ) . 81. 3% cases graded Gleason Score 6 in biopsy was assigned to Gleason Score 7 or more in prostatectomy. Conclusions Completely sampling radical prostatectomy specimen should be recommended for accurate staging and margin status. Preoperative PSA value, Gleason Score of biopsy, involved core number by cancer is a still helpful parameter for clinical staging and risk estimate.
8.Study on expression of TPS, VEGF of beast cancer patients and relationship with clinical pathological
Daobao CHEN ; Hongjian YANG ; Bo CHEN ; Xingfei YU ; Weiliang FENG
Chinese Journal of Biochemical Pharmaceutics 2015;37(5):121-123
Objective To investigate expression of TPS, VEGF of beast cancer patients and relationship with clinical pathological.Methods 68 cases of breast cancer were selected as experiment group, 36 cases with breast fibroma were selected as control group.TPS and VEGF were detected by elisa of patients before and after treatment.Serum TPS and VEGF levels and TNM staging were compared after operation.Results TPS and VEGF of the experiment group were higher than control group(P<0.05).TPS and VEGF of experiment group after operation were higher than before operation.TPS and VEGF increased with the grade of tumor, but there was no significance between grade Ⅰ and 0.The expression of VEGF in tumor diameter≤2 cm group was significantly lower than >2 cm group(P<0.05).TPS and VEGF of axillary lymph node metastasis group and axillary lymph node metastasis had significant difference(P<0.05).The concentration of TPS was significantly higher than that of estrogen and progesteronepositive group in estrogen receptor negative, progesterone receptor negative (P<0.05).Conclusion TPS, VEGF levels in the serum of breast cancer patients showed high expression, the expression of TPS, VEGF levels related to axillary lymph node metastasis, estrogen receptor, progesterone receptor.
9.Effectiveness and safety of intravenous recombinant tissue plasminogen activator thrombolysis therapy for acute ischemic stroke patients with atrial fibrillation
Shunyuan GUO ; Bo CHEN ; Zongjie SHI ; Kenan CHEN ; Yu GENG
Chinese Journal of Emergency Medicine 2014;23(12):1314-1318
Objective To study the effectiveness and safety of intravenous recombinant tissue plasminogen activator (rt-PA) thrombolysis therapy for acute ischemic stroke in patients with atrial fibrillation (AF).Methods A total of 94 patients treated with intravenous rt-PA thrombolysis within 4.5 hours after cerebral stroke onset were analyzed and divided into two groups:a non-AF group (n =64) and an AF group (n =30).Another 30 acute ischemic stroke patients with AF without thrombolytic therapy were selected as a control group.The prognosis of the three groups was compared.The National Institute of Health Stroke Scale (NIHSS) was used for comparison among the three groups before therapy and 7 days after therapy.The incidences of intracerebral hemorrhage (ICH) and symptomatic ICH (SICH) were recorded.The patients were followed up for 90 days and their clinical outcomes were assessed by using the modified Rankin scale (mRS).Results There were no significant differences in the NIHSS scores among three groups before treatment (P > 0.05).The NIHSS scores were significantly lower in the AF and non-AF groups 7 days after thrombolysis therapy than those before thrombolysis therapy (P <0.05 and P <0.01),and no significant difference in the NIHSS scores was found in the control group before and after therapy (P > 0.05).The incidence of ICH was significantly higher in the AF group than in the non-AF group (26.7% vs.9.4%,P < 0.05).No significant difference in the incidence of SICH was found between the AF and non-AF groups (13.3% vs.6.3%,P > 0.05).The favorable prognosis rate was higher in the AF and nonAFgroups than in control group (40.0% vs.16.7%,P<0.05; 45.3% vs.16.7%,P<0.01).No significant difference in very unfavorable prognosis rate was found between the AF and non-AF groups (20.0% vs.18.8%,P >0.05).Conclusions It is effective and safe of rt-PA thrombolysis therapy for acute ischemic stroke patients with AF.
10.ERG rearrangement prevalence in Chinese prostatic carcinoma biopsy cohort
Li XIAO ; Yulei YIN ; Yan CHEN ; Chen LU ; Bo YU
Chinese Journal of Clinical and Experimental Pathology 2015;(10):1110-1114
Purpose To study the prevalence and feature of EGR gene rearrangement in prostatic carcinoma. Methods 242 consecu-tive core biopsies of prostatic carcinoma were evaluated. All biopsy specimens contained 6-14 cores from left and right sides separately delivered. The patient age ranged 58 to 91 years, and PSA value 5 ng/ml to more than 5 000 ng/ml. Immunohistochemistry ( IHC) for ERG protein overexpression and fluorescent in situ hybridization ( FISH) for ERG gene rearrangement were performed. Results 42 cases were detected positive for ERG by IHC ( positive rate 17. 4%) , and positive for ERG rearrangement by FISH either, with 19 ca-ses showing fusion through deletion and 23 through insertion, while no negative cases by IHC demonstrated positive by FISH. 5 cases revealed positive and negative staining in different carcinoma foci of ERG. No ERG positive staining and rearrangement were found in adjacent benign glands. Of positive cases, 12 cases were graded as Gleason score 6, 23 Gleason score 7, and 7 Gleason score 8 or more. Positive rate was 19. 6% in the group of PSA value less than 100 ng/ml, and 10% of more than 100 ng/ml, whereas 17. 2% in the group of clinical T3 stage or less, and 19% of clinical T4 and lymph node or remote metastasis. ERG rearrangement was associated with lower Gleason score, but not with PSA value, clinical stage and progression using theχ2 test analysis. Conclusions IHC is relia-ble for detection ERG rearrangement and helpful for interpretation of prostatic carcinoma. Multiple foci are common in prostatic carcino-ma. There is no significance between ERG rearrangement and disease prognosis.