1.A Seroepidemiologic Study on Rubella Antibody Positivity: Primary School Students in Gyenggi-Do.
Bo Youl CHOI ; Hung Bae PARK ; Young Jeon SHIN ; Bae Joong YOON ; Jong Surk HAHN
Korean Journal of Epidemiology 1995;17(2):156-166
PURPOSE: The purpose of this seroepidmiologic study was to examine the immunization and infection history of rubella, positivity of rubella specific antibody, seroconversion rate of two rubella vaccines and to develop an adequate immunization program of rubella. Research Methods : Subjects of the study were 2.071 students of 8 priamary schools in Gyenggi-Do. Questionnaire and blood sampling were done. Test method of Rubella specific antibody was ELISA (Abbott IMx autoanalyzer). The anayltic methods for the study were chi-square-test, t-test and ANOVA. RESULTS: The results of the study were as follows : (1)The number of subjects who had infection history of rubella were only 28 students(1.5%). (2)The immunization rate of rubella was the highest in 6 year-old group(65%), it decrease as subjects grow older. (3)The positivity of rubella antibody was 76. 6%, it is the highest in 6 year old group and the lowest in 7 year-old group and it increase again as subjects grow older. (4)Average antibody titer was 53.3 IU(SD 79.2), the trend of antibody titer by age was similar to that of positivity. (5)The seroconversion rates of both vaccines, vaccine A,vaccine B, were 99.5% and 99.6%, the ratio of increase of antibody titer after immunization was higer than 400. it means that both vaccines are very efficacious. CONCLUSION: Results of the study suggest that it is necessary to increase the coverage of rubella immunization, and further studies are necessary to get more information for rubella.
Child
;
Enzyme-Linked Immunosorbent Assay
;
Humans
;
Immunization
;
Immunization Programs
;
Rubella*
;
Seroepidemiologic Studies*
;
Vaccines
;
Surveys and Questionnaires
2.A Pediatric Case of Acute Myeloid Leukemia with t(3;5)(q25;q34)
Clinical Pediatric Hematology-Oncology 2014;21(2):149-152
Acute myeloid leukemia (AML) with t(3;5)(q25;q34), belonging to AML with myelodysplasia related changes according to WHO classification in 2008, is a subtype of AML that is particularly rare in children. NPM1/MLF1 fusion gene produced as a result of t(3;5)(q25;q34) was cloned, however, the exact mechanism of its role in leukemogenesis has not been clarified. Although this cytogenetic abnormality is regarded as an intermediate risk factor, its clinical significance is controversial until now. More cases need to be reported and investigated, therefore we present a case of AML with t(3;5)(q25;q34) in a 14-year-old girl with literature review.
Adolescent
;
Child
;
Chromosome Aberrations
;
Classification
;
Clone Cells
;
Female
;
Humans
;
Leukemia, Myeloid, Acute
;
Risk Factors
4.Effects of IL-12 DNA Vaccine on Reactivation of Mycobacterium tuberculosis in Cornell Model.
Bo Young JEON ; Manki SONG ; Seung Cheol KIM ; Young Cheol SUNG ; Joo Deuk KIM ; Sang Nae CHO
Journal of the Korean Society for Microbiology 2000;35(5):378-378
No Abstract Available.
DNA*
;
Interleukin-12*
;
Mycobacterium tuberculosis*
;
Mycobacterium*
5.Semiquantitative Food Frequency Method as an Epidemiological tool in a Rural community, Korea.
Mi Kyung KIM ; Bo Youl CHOI ; Young Jeon SHIN ; Yoon Ok AHN ; Sang Sun LEE ; Young Sun CHO
Korean Journal of Epidemiology 1994;16(1):54-65
This study was performed to evaluate the semiquantitative food frequency questionnaire used to obtain information about. dietary patterns of adults in a rural county, Yang-pyeung Gun. The study population was 1311 adults aged 17~85 years. And well-trained interviewers interviewed subjects in 1990, 1992, 1993. The results are as follows. 1) Nutrients intake calculated from each questionnaire showed significant difference, because the number of question was not same(fifty questions in 1990, eighty questions in 1992, 1993). 2) Estimated nutrients intake from separate food items was significantly different when food items are combined in one question. 3) The agreement of nutrients intake level except vit C were high when the subjects are cross-classified by their ranks on the nutrients intake level from items in both questionnaires and on the nutrient intake level from items in each questionnaire. 4) And analysing this study data by multiple stepwise regression, we selected twenty seven food items whic could explained over 85% of inter-individual variation of nutrients(energy, carbohydrate, fat, protein, vit A, vit B1, vit B2, vit C, Ca). From above results, we suggested that it is neccessary to standardize questionnaire and perform validity studies.
Adult
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Humans
;
Korea*
;
Rural Population*
;
Surveys and Questionnaires
6.A Case of Solitary Metastatic Iris Tumor from Bronchogenic Carcinoma: Responese to Chemotherapy.
Sang Jin KIM ; Chang Bo SHIM ; Joon Sup OH ; Young June JEON
Journal of the Korean Ophthalmological Society 1988;29(2):453-457
Metastatic tumors to the eye are probably the most common type of intraocular malignancies. The choroid is the most common site of involvement. Though the iris is a less common site of uveal involvement, metastases to the iris may occur and may produce a variety of clinical findings. The most common metastatic tumor to the eye is breast tumor and lung tumor is second, whereas the prompt most common metastatic tumor to the iris is lung tumor and breast tumor is second. The iris lesion may be the first presentation of the cancer and should make a search for the primary tumor. The diagnosis of metastatic tumor to the iris can be established by cytologic examination of aqueous. Local irradiation can spare the patient an enucleation and can preserve the eye for the generally few months of life that remain. Although the prognosis for vision is usually good, the prognosis for life is poor. The authors describe a 37 year old male patient having a metastasis from oat cell carcinoma of the lung to iris, which begins to respond to chemotherapy.
Adult
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Breast Neoplasms
;
Carcinoma, Bronchogenic*
;
Carcinoma, Small Cell
;
Choroid
;
Diagnosis
;
Drug Therapy*
;
Humans
;
Iris*
;
Lung
;
Male
;
Neoplasm Metastasis
;
Prognosis
7.Evaluation of Plasma and Urinary Tumor Necrosis Factor alpha Interleukin-2 Receptor and Interleukin-6 Levels in Renal Allograft Recepients.
Yong Sung JEON ; Jeong Ouk KO ; Woo Hyung KWUN ; Young Soo HUH ; Bo Yang SUH ; Koing Bo KWUN
The Journal of the Korean Society for Transplantation 1999;13(1):45-54
This is the report of 98 cases in renal allograft, which were treated at Yeungnam University Hospital from January 1994 to July 1996 and compared the significance of changes of TNF alpha, IL-2R, IL-6 in blood and urine as an early diagnostic tool of acute rejection in renal allograft. The aim of this study was to investigate the value of plasma and urinary TNF alpha, IL-2R, IL-6 in patients with renal allografts. Renal allografts patients were divided into four groups (control, acute rejection, acute tubular necrosis, systemic infection) according to their postoperative diagnostic methods. Blood and urine samples in four groups were obtained: control group (2 days before transplantation, at the day of transplantation and every other day after transplantation), acute rejection group (everyday sampling from 2 days before therapy to the end of therapy), acute tubular necrosis and systemic infection group (everyday sampling from the day of diagnosis to the end of therapy). In acute rejection group, there were significant elevation of cytokines; plasma TNF alpha (68.4%, p<0.01), IL-2R (73.6%, p<0.01), and IL-6 (89.5%, p<0.01), urinary TNF-alpha (42.1%, p<0.01), IL-2R (89.5%, p<0.01) and IL-6 (94.7%, p<0.01). In systemic infection group, all cytokines except urinary TNF-alpha were significantly elevated. The results suggested that plasma and urinary TNF-alpha, IL-2R, and IL-6 may play a complementary early diagnostic tool of acute rejection in renal allograft patients although the differential diagnosis is difficult with systemic infection. Urinary TNF-alpha was not elevated in systemic infection group, so it may be used in differential diagnosis between acute rejection and systemic infection.
Allografts*
;
Cytokines
;
Diagnosis
;
Diagnosis, Differential
;
Humans
;
Interleukin-6*
;
Necrosis
;
Plasma*
;
Tumor Necrosis Factor-alpha*
8.Evaluation of Plasma and Urinary Tumor Necrosis Factor alpha Interleukin-2 Receptor and Interleukin-6 Levels in Renal Allograft Recepients.
Yong Sung JEON ; Jeong Ouk KO ; Woo Hyung KWUN ; Young Soo HUH ; Bo Yang SUH ; Koing Bo KWUN
The Journal of the Korean Society for Transplantation 1999;13(1):45-54
This is the report of 98 cases in renal allograft, which were treated at Yeungnam University Hospital from January 1994 to July 1996 and compared the significance of changes of TNF alpha, IL-2R, IL-6 in blood and urine as an early diagnostic tool of acute rejection in renal allograft. The aim of this study was to investigate the value of plasma and urinary TNF alpha, IL-2R, IL-6 in patients with renal allografts. Renal allografts patients were divided into four groups (control, acute rejection, acute tubular necrosis, systemic infection) according to their postoperative diagnostic methods. Blood and urine samples in four groups were obtained: control group (2 days before transplantation, at the day of transplantation and every other day after transplantation), acute rejection group (everyday sampling from 2 days before therapy to the end of therapy), acute tubular necrosis and systemic infection group (everyday sampling from the day of diagnosis to the end of therapy). In acute rejection group, there were significant elevation of cytokines; plasma TNF alpha (68.4%, p<0.01), IL-2R (73.6%, p<0.01), and IL-6 (89.5%, p<0.01), urinary TNF-alpha (42.1%, p<0.01), IL-2R (89.5%, p<0.01) and IL-6 (94.7%, p<0.01). In systemic infection group, all cytokines except urinary TNF-alpha were significantly elevated. The results suggested that plasma and urinary TNF-alpha, IL-2R, and IL-6 may play a complementary early diagnostic tool of acute rejection in renal allograft patients although the differential diagnosis is difficult with systemic infection. Urinary TNF-alpha was not elevated in systemic infection group, so it may be used in differential diagnosis between acute rejection and systemic infection.
Allografts*
;
Cytokines
;
Diagnosis
;
Diagnosis, Differential
;
Humans
;
Interleukin-6*
;
Necrosis
;
Plasma*
;
Tumor Necrosis Factor-alpha*
9.The efficacy of denture cleansing agents: A scanning electron microscopic study.
Bo Hyeok YUN ; Mi Jung YUN ; Jung Bo HUR ; Young Chan JEON ; Chang Mo JEONG
The Journal of Korean Academy of Prosthodontics 2011;49(1):57-64
PURPOSE: The purpose of this study was to compare the cleansing performance of a distilled water, a diluted solution of sodium hypochlorite as a household bleaching cleanser and three alkaline peroxide cleansers in vivo plaque deposits by using scanning electron microscope. MATERIALS AND METHODS: Five individuals were selected from department of the prosthodontics in Pusan National University Hospital, and each of them was inserted with specimens for plaque accumulation in their temporary dentures for 48 hours. The specimens were removed and cleaned by each cleansing agents for 8 hours. Scanning electron micrographs were made from the specimens at a magnification of x2,000. A panel of ten persons with a dental or paradental background, but not directly involved in the study, was selected to analyze the photomicrographs to determine which denture cleanser was more effective in removing plaque. RESULTS: Diluted solution of sodium hypochlorite was the most effective at removing plaque following Polident(R), Cleadent(R)e, Bonyplus(R) and distilled water in order. But there was no significant difference of cleansing efficacy between diluted solution of sodium hypochlorite and Polident(R), Polident(R) and Cleadent(R)e, Cleadent(R)e and Bonyplus(R), respectively (P > .05). Alkaline peroxide cleansers by themselves cannot adequately remove accumulated plaque deposits, especially if the deposits are heavy. Corrosion could be seen on the surface of non-precious alloy specimens immersed in diluted solution of sodium hypochlorite. CONCLUSION: It is recommended to use of alkaline peroxide type cleansers with brushing whenever possible, since denture cleanliness is often poor due to the relative inefficiency of these cleansers.
Alloys
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Corrosion
;
Denture Cleansers
;
Dentures
;
Detergents
;
Electrons
;
Family Characteristics
;
Humans
;
Prosthodontics
;
Sodium
;
Sodium Hypochlorite
;
Water
10.Cockarde (Target-Like Lesion) Seborrheic Keratosis: An Unusual Clinical Pattern.
Na Young YOON ; Bo Kyung KIM ; Seung Phil HONG ; Soo Young JEON ; Sung Ku AHN
Annals of Dermatology 2013;25(4):512-514
No abstract available.
Keratosis, Seborrheic*