1.Research on digital performance evaluation of large medical equipment
China Medical Equipment 2014;(10):5-7
Objective:Performance appraisal of large-scale medical equipment has a significant impact on hospital management. Process equipment performance evaluation of digital is an important part of digital medical&hospital. How to fully utilize the large number of advanced medical equipment resources, how to monitor and manage equipment are focuses that hospital administrators pay much attention to. Methods: The effective performance appraisal of large-scale medical equipment can promote the resource allocation optimization, accurate and scientific management, reasonable and benign application, and then allows large-scale medical equipment fully and effectively applied to clinical practice. Results: Collecting basic data is the basis for performance appraisal of large-scale medical equipment; its instant validity, accuracy, and scientific can enhance the operability and the scientific accuracy of the performance appraisal for large-scale medical equipment. Conclusion:The acquisition of basic data has few specialized research in previous studies, the rules set up for basic data acquisition of large-scale medical equipment in this paper can improve the timeless, accuracy and normalization of the basic data using in the performance appraisal of large-scale medical equipment.
3.Diagnosis and treatment of multi-center breast intraductal carcinoma
Zhi LI ; Bo CHENG ; Bo ZHANG ; Tao HUANG
Chinese Journal of General Surgery 2011;26(2):109-111
Objective To investigate clinical characteristics of the multi-center breast DCIS (ductal carcinoma in situ), in order to improve the rate of early diagnosis. Methods Clinical data of 23 multi-center breast DCIS patients admitted and operated on from September 2003 to February 2009 at our department were retrospectively reviewed. Results There were 4 cases associated with nipple discharge,and 18 cases with preoperative negative physical examination (78%). In the preoperative examination within 6 months, the positive rate of mammography was 90% mainly characterized by the existence of diffuse and multiple small calcifications. The positive rate of MRI was 25%, B ultrasound had no positive findings. The patients that were confirmed multi-center breast DCIS by intraoperative frozen section examination received mastectomy and ipsilateral axillary L1, L2 lymph node dissection. Conclusion The diffuse and multiple small calcification is one of early clinical characteristics of multi-center breast DCIS. Although the disease has a wide range of lesion, it still is an early tumor, and has a favourite prognosis after comprehensive treatment.
4.Clinical application and complications of cerebrovascular stents
Bo LIU ; Bangli WU ; Xuehu ZHANG ; Tao ZHANG
Chinese Journal of Tissue Engineering Research 2009;13(39):7747-7750
OBJECTIVE: To introduce advances of cerebrovascular stent at home and abroad, analyze causes for complications following stenting and explore the biocompatibility of cerebrovascular stent and host.METHODS: A computer-based online search of Medline database (1989/2009) and CNKI (1989/2009) was performed to select related articles. According to inclusion and exclusion criteria, the collected articles were selected and evaluated. The treatment advances, complications, and stent biocompatibility were described and summarized to explore the current status, complication and biocompatibility of various cerebrovascular stents.RESULTS: The content of articles was summarized. Intracranial stent is commonly used in clinic. The diameter of vessels confines diameter of stent, so different diseases have different requirements for diameter of stents. The complications following stenting include retroperitoneal hematoma, carotid sinus, hypertransfusion syndrome, cerebral angio spasm and thrombosis. In various stents, polymer, eluting and drug stents have better biocompatibility compared with metal stent, and can effectively prevent restenosis.CONCLUSION: Cerebrovascutar stenting is one of the treatments for cerebrovascular diseases. During the treatment, sufficient operative preparation, appropriate stent and indication are important to avoid complications. Of various stents, polymer and drug stents have good biocompatibility, and the biocompatibility of other stents requires improvement.
5.A Strategy for Bioproduction of Rare Sugars: Izumoring
Wan-Meng MU ; Tao ZHANG ; Bo JIANG ; Hua ZHANG ;
China Biotechnology 2006;0(07):-
Rare sugars were defined as monosaccharides and their derivatives that rarely exist in nature. They played an important role in food, health, medicine and etc A strategy for bioproduction of rare sugars, namely Izumoring, was described. By the Izumoring method, all monosaccharides and polyols could be linked, using enzymatic reaction with D-tagatose 3-epimerase, aldose isomerases and polyol dehydrogenases. Izumoring for hexoses, pentoses and tetroses were designed respectively. According to this strategy, the bioproduction routes of various rare sugars, using microbial and enzymatic reactions, could be obtained. In addition, the future research tendency of biotransformation of rare sugars was put forward.
7.Engineering of the xylose metabolic pathway for microbial production of bio-based chemicals.
Weixi LIU ; Jing FU ; Bo ZHANG ; Tao CHEN
Chinese Journal of Biotechnology 2013;29(8):1161-1172
As the rapid development of economy necessitates a large number of oil, the contradiction between energy supply and demand is further exacerbated by the dwindling reserves of petroleum resource. Therefore, the research of the renewable cellulosic biomass resources is gaining unprecedented momentum. Because xylose is the second most abundant monosaccharide after glucose in lignocellulose hydrolyzes, high-efficiency bioconversion of xylose becomes one of the vital factors that affect the industrial prospects of lignocellulose application. According to the research progresses in recent years, this review summarized the advances in bioconversion of xylose, which included identification and redesign of the xylose metabolic pathway, engineering the xylose transport pathway and bio-based chemicals production. In order to solve the energy crisis and environmental pollution issues, the development of advanced bio-fuel technology, especially engineering the microbe able to metabolize xylose and produce ethanol by synthetic biology, is environmentally benign and sustainable.
Bacteria
;
genetics
;
metabolism
;
Escherichia coli
;
genetics
;
metabolism
;
Ethanol
;
metabolism
;
Fermentation
;
Fungi
;
genetics
;
metabolism
;
Industrial Microbiology
;
methods
;
Metabolic Engineering
;
Metabolic Networks and Pathways
;
genetics
;
Saccharomyces cerevisiae
;
genetics
;
metabolism
;
Xylose
;
metabolism
8.Effect of ropivacaine combined with dexamethasone sprayed intratracheally in patients with resistant tubes and postoperative sore throat
Yingxin ZHANG ; Guanhua LI ; Bo SUI ; Wei WANG ; Tao MA
Chinese Journal of Postgraduates of Medicine 2014;37(6):26-29
Objective To investigate the effect of ropivacaine combined with dexanmethasone sprayed intratracheally in patients with resistant tubes and postoperative sore throat.Methods Eighty patients ASA Ⅰ-Ⅱ grade undergoing laparoscopic cholecystectomy were randomly divided into four groups by random digits tabel method,20 patients in each.2 ml of 0.75% ropivacaine combined with 1 ml dexamethasone (group A) ; 2 ml of 0.75% ropivacaine combined with 1 ml 0.9% sodium (group B) ; 3 ml of 1% tetracaine (group C); 3 ml of 0.9% sodium (group D) were immediately intratracheal sprayed before intubation.The resistant tubes and degree of postoperative 24 h sore throat [by visual analog scale (VAS) scores],comfort [by Bruggrmann comfort scale (BCS) scores] and the incidence of sore throat were recorded.Results The resistant tubes appraised rate in group A,B and C was higher than that in group D [65.0% (13/20),60.0% (12/20),70.0% (14/20) vs.5.0% (1/20)] (P < 0.05),but there was no significant difference among group A,B and C (P> 0.05).The incidence of sore throat at 24 h after surgery in group A,B and C was lower than that in group D [20.0%(4/20),25.0% (5/20),25.0% (5/20) vs.90.0% (18/20)] (P < 0.05),but there was no significant difference among group A,B and C (P> 0.05).The VAS and BCS scores in group A were better than those in group B,C and D [(0.52 ± 1.14) scores vs.(1.68 ± 1.42),(1.59 ± 1.33),(4.22 ± 1.95) scores,(2.80 ± 1.54) scores vs.(1.60 ± 1.19),(1.80 ± 1.20) and (0.45 ± 0.81) scores] (P < 0.05),but there were no significant differences between group B and group C (P > 0.05).Conclusion Ropivacaine combined with dexamethasone sprayedintratracheally can significantly increase the degree of postoperative resistant tubes,decrease the rate of sore throat after general anesthesia,and increase patient' s comfort.
9.Study on clinical characteristics of hypertension in patients with Cushing′s syndrome
Bo ZHANG ; Hong TAO ; Zhaolin LU ; Yue WANG
Chinese Journal of Endocrinology and Metabolism 1985;0(01):-
25 years group. Among 129 cases who had taken antihypertensive drugs before operation, only 43 cases continued to use drugs after operation, therefore, rate of antihypertensive drugs administration decreased significantly after operation (P
10.The development of a cirrhotic model and portal vein delivery system in rabbit
Bo JIN ; Liufang CHENG ; Zhicheng ZHANG ; Tao SUN
Journal of Chinese Physician 2002;0(S1):-
Objective To explore a method for development of carbon tetrachloride-induced cirrhotic model in rabbit and establish a portal vein delivery system in this model.Methods Male New Zealand white rabbit was subcutaneously injected carbon tetrachloride twice weekly,and the liver pathology and hepatic hydroxyproline content were examined after 12 weeks of injection.Portal vein catheterization was introduced through the terminal branch of mesostenium vein.The injection end of the catheter was embedded subcutaneously in the abdominal wall of the animal.The portal delivery was implemented by percutaneous puncture of the injection cap.Results After 12 weeks' of carbon tetrachloride administration,the rabbit liver developed typical pseudo lobule,and the liver hydroxyproline content increased 3.5 times compared to normal control.The portal vein delivery system could be maintained as long as 12 weeks.Conclusion A successive method to induce rabbit liver cirrhosis is developed,and a simple and economic animal portal vein delivery system is introduced.