1.Choice and reasonable application of staplers for gastrointestinal surgery.
Chinese Journal of Gastrointestinal Surgery 2013;16(7):601-604
Digestive tract reconstruction is the main part of gastrointestinal surgery. With the rapid development of technology and widely application in stapling device, more and more surgeons are using stapled anastomosis. Stapled anastomosis is associated with shorter operating time and hospital stay than hand-sewn anastomosis. However, it is not easy to select suitable ones from various staplers and use them correctly. Choice and reasonable application of staplers for anastomosis in gastrointestinal surgery are summarized and evaluated in this article.
Anastomosis, Surgical
;
instrumentation
;
Digestive System Surgical Procedures
;
instrumentation
;
Humans
;
Surgical Staplers
2.The reserve of tissue plasminogen activator and nitric oxide in endothelium and its relation to vasodilation in diabetic patients
Bo FENG ; Lin CHEN ; Yunzhou HUANG
Chinese Journal of Endocrinology and Metabolism 2001;0(05):-
Objective To study the changes in the endothelial reserve capacity to release tissue plasminogen activator (tPA) and nitric oxide (NO) and its relation to vasodilation and to diabetic angiopathy. Methods The capacity of vascular endothelium to release tPA and NO was examined by venous occlusion of the upper arm. Brachial artery diameter was measured at baseline, during postocclusion reactive hyperemia (flow-mediated endothelium-dependent), and after sublingual nitroglycerol administration (endothelium-independent), using a high resolution ultrasound technique in 15 control subjects and 23 patients with type 2 diabetes mellitus. Vasodilation was expressed as the percentage change relative to the baseline diameter, while endothelial tPA and NO release was expressed as the percentage change relative to the baseline tPA and NO levels. Thickness of the intima of carotid artery was measured using ultrasound imaging. Results There was no significant difference in endothelium-independent vasodilation between control subjects and diabetics. However, significant reductions in endothelium-dependent vasodilation (P
3.Diagnostic value of positron emission tomography in gastric malignancy: a preliminary study
Qinglong KONG ; Lin CHEN ; Bo WEI
Medical Journal of Chinese People's Liberation Army 2001;0(08):-
Objective To evaluate the diagnostic value of positron emission tomography(PET) with the use of 18 F-fluorodeoxyglucose(FDG) in patients with gastic malignancy. Methods 18 F-FDG PET examination was performed for twenty three patients suspected to be suffering from gastric malignancy,and the results were evaluated against histopathological staging. Results The diagnostic accuracy of primary lesion by PET was 87.0%. When using a mean standard uptake value (SUVmear and SUVmax) with a cut-off of 2.5,the sensitivity was 86.2%(19/23)and 91.3%(21/23),respectively. The accuracy in identifying lymph node metastases and distant metastases by PET was 78.9%(15/19) and 7/8,respectively. Conclusion PET scanning is sensitive in the diagnosis of primary malignant lesion and metastatic lesion in patients suspected to have gastric cancer. It provides a valuable reference in the diagnostic evaluation,option of surgical strategy,and treatment in patients with gastric carcinoma.
4.In vitro bacterial resistance monitoring of urinary tract infectious in female elderly patients
Guangling LIN ; Linxing CHEN ; Meishan LIN ; Hongni GU ; Bo LIU
Clinical Medicine of China 2011;27(3):264-266
Objective To determine the distribution and antibiotics resistance characteristic of pathogens in urinary tract infections in aged female diabetics patients and provide scientific basis for clinicians in selecting effective antibiotics. Methods Pathogenic bacteria, isolated from specimens of 107 elderly female diabetic cases with urinary tract infections, were identified and drug susceptibility tests were performed by VITEK-32 analysator. Results Among all 107 kinds of isolated bacteria,the ratio of gram-negative bacteria was 74. 8% ( 80/107 ), predominated by Escherichiacoli ( accounting for 48. 6% [52/107] ); the ratio of gramposition bacterias was 13. 1% (14/107) and eumycetes was 12. 1% (13/107). In antibiotic resistance analysis,the gram negative bacteria showed higher drug-resistance to the some common-antibiotics, such as ampicililin,cefazolin,cefuroxime-sodium and cefuroxime axetil ( > 70. 0% ), while they were sensitive to imipenem and amikacin( < 10. 0% ). The gram positive bacteria were most sensitive to vancomycin (0%), followed by Linezolid(7.7% ). Conclusion Escherichiacoli were the major pathogenic bacteria in urinary tract infections in aged female diabetic patients, with higher drug resistance. Therefore, drug resistance monitoring should be carried out according to the variety of pathogenic bacteria so as to guide rational use of antibiotics and decrease drug resistance.
5.The anti-inflammatory mechanisms of ?-melanocyte-stimulating hormone
Bo CHEN ; Chaofeng HU ; Huadong WANG ; Chen LIN ; Chuji LI
Chinese Journal of Pathophysiology 1986;0(03):-
?-MSH is an endogenous neuropetide that is effective of all categories of expreimental inflammation. The mechanisms underlying the anti-inflammatory influence of ?-MSH are reviewed in the article. ?-MSH suppresses inflammation in the CNS and periphery by downregulating the activation of NF-?B, then inhibiting production of proinflammatory cytokines, nitric oxide, chemokines and adhension molecules, and increasing synthesis of anti-inflammatory cytokines. ?-MSH is useful in the treatment of many pathological situations in humans.
6.Clinical application of moving cupping therapy based on skin reaction observation and syndrome differentiation.
Xiao-Lan DENG ; Bo CHEN ; Ze-Lin CHEN
Chinese Acupuncture & Moxibustion 2014;34(12):1215-1216
The diagnostic evidence on clinical diseases and theoretic basis of moving cupping therapy were ex- plored in the paper. By the observation of the local reaction, such as skin appearance and color, the affected location, duration of sickness and nature of disease were judged. Different moving cupping methods were selected for different disorders. It was discovered that the property of syndromes should be recognized by the palpation on skin and muscle in the moving cupping therapy so that the pathogenesis and treating principle could be carefully determined. The moving cupping therapy is the important component of body surface therapy. Skin reaction observation and syndrome differentiation is the essential guidance of the moving cupping therapy.
Acupuncture Points
;
Acupuncture Therapy
;
Humans
;
Meridians
;
Skin
;
anatomy & histology
;
blood supply
7.The anti-inflammatory mechanisms of α-melanocyte-stimulating hormone
Bo CHEN ; Chaofeng HU ; Huadong WANG ; Chen LIN ; Chujie LI
Chinese Journal of Pathophysiology 2001;17(3):281-284
α-MSH is an endogenous neuropetide that is effective of all categories of expreimental inflammation. The mechanisms underlying the anti-inflammatory influence of α-MSH are reviewed in the article. α-MSH suppresses inflammation in the CNS and periphery by downregulating the activation of NF-κB, then inhibiting production of proinflammatory cytokines, nitric oxide, chemokines and adhension molecules, and increasing synthesis of anti-inflammatory cytokines. α-MSH is useful in the treatment of many pathological situations in humans.
9.Pilot study of laser-doppler flowmetry measurement of oral mucosa blood flow
Ying WANG ; BARRY OBADA ; WAHL GERHARD ; Bo CHEN ; Ye LIN
Journal of Peking University(Health Sciences) 2016;48(4):697-701
Objective:To explore and compare the perfusion pattern of oral mucosa on Han Chinese and Caucasian by laser-doppler flowmetry.Methods:A cross-sectional study was carried out,in 20 healthy Han Chinese adult subjects (average age:28.4 years)and 20 healthy Caucasian (average age:25.3 years)adult subjects,either gender with 10 subjects.Gingival perfusion was evaluated at 8 points (including upper incisor labial gingival,lower incisor labial gingival,palatal mucosa,cheek mucosa) using a laser-doppler flowmetry(O2C,Medizintechnik GmbH,Germany).Each measurement was car-ried out 25 seconds consisting 5 seconds of foreperiod and 20 seconds of work period,without pressure. The measurements were taken by two well-trained doctors,each measurement was exammed 3 times by an examiner,and the average value was recorded as final data.Each measurement has 4 parame ters:SpO2 (oxygen saturation),rHB (relative amount of hemoglobin),flow (the blood flow of unit interval),and velocity (blood flow velocity).We compared the data by different sites,different genders,and different races.Results:For palatal gingival,the average SpO2 was 77.1% ±10.9%,the average rHB 67.8 ± 11.1,and the average flow 194.1 ±63.7,which presented significant lower values than other oral muco-sa.There was no significant difference among other sites.There was some significant difference between the Caucasian and the Han Chinese:the maxillary central incisor oxygen saturation (SpO2)which were averages of 75.6% ±8.2% and 70.4% ±7.6%;buccal mucosa hemoglobin (rHB)averages of 79.9 ±5.8 and 83.5 ±6.6,which had statistical differences.For most measurement points,the oxygen saturation on men was lower than that on women,which had significant difference.Conclusion:To inves-tigate microcirculation pattern,oral mucosa can be the good observation site.Laser-doppler flowmetry is a well-documented instrument to survey on microcirculation.There may be differences between the genders in hemoglobin oxygen-binding capacity,which may have some impact on the ability of soft tissue healing. Oral mucosa display more blood perfusion than attached gingival.As the recipient site of gingival graft, maxilla and mandible have slight difference in blood supply.
10.Early clinical evaluation of dental implants in patients with chronic localized periodontitis
Bo KANG ; Lvhua GUO ; Jianzhao CHEN ; Li′E LIN ;
Journal of Practical Stomatology 2001;0(01):-
Objective:To investigate the clinical results of implantation in patients with chronic localized periodontitis.Methods: 21 patients with chronic localized periodontitis who received 57 implants were studed.The patients were followed up for one year after implants loading.Results: There were 4 implantation failures.Another 53 implants had a good osseointegration.The success rate was 92.98%.The marginal bone resorption was about(0.77?0.32) mm after one year loading.Conclusion: The clinical outcome of dental implants in selected group of patients with well-controlled chronic localize periodontitis is satisfying.Further investigations and clinical trials is needed to determine the long-term survival of implants in patients with chronic localize periodontitis.