1.Expression of the hepatitis C virus proteinase isolated in Korean.
Journal of the Korean Society of Virology 1993;23(2):193-202
No abstract available.
Hepacivirus*
;
Hepatitis C*
;
Hepatitis*
2.High Lumbar Disc Herniations.
Hwan Mo LEE ; Nam Hyun KIM ; Yong Ho KANG ; Bo Yang KIM
Journal of Korean Society of Spine Surgery 1998;5(1):109-115
STUDY DESIGN: This study is a retrospective evaluation of the high lumbar disc herniations. OBJECTIVE: The purposes of this study is to observe the clinical and radiological findings and out-comes of the high lumbar disc herniations, thus providing a guideline for making diagnosis and for proper treatment modality. SUMMARY OF LITERATURE REVIEW: High lumbar disc herniations at the L1 -2, L2-3 and L3-4 levels represent less than 5% of all disc herniations. The location of pain was highly complected. The represented symptoms and signs such as motor, sensory and reflex changes were variable and potentially misleading in suggesting a level of the disc herniation. MATERIAL AND METHODS: Thirty-one patients with high lumbar disc herniations were retrospectively evaluated. Seventeen patients were treated conservatively and fourteen patients underwent surgery. Review of results was undertaken by an independent observer using a proven outcome assessment measure. RESULTS: The incidence of high lumbar disc herniation is 4.7%(L1-2: 13%, L2-3: 29%, L3-4: 58%) with declining frequency as the level ascends. The peak age incidence is 6th decade in male and 5th decade in female. The positive rate of femoral nerve stretching test(74%) is higher than that of straight leg raising test(51%). In fourteen operative cases, the positive rate of straight leg raising test is 86%. The accuracy of MRI findings in predicting the type of herniated disc is 93%. In results of operation thirteen cases showed more than fair grade(93%). CONCLUSION: The age incidence of the high lumbar disc herniation is older than that of the lower lumbar disc herniation. The femoral nerve stretching test is more useful than straight leg raising test in making diagnosis of high lumbar disc herniations. The prognosis after treatment is comparable with high lumbar disc herniations.
Diagnosis
;
Female
;
Femoral Nerve
;
Humans
;
Incidence
;
Intervertebral Disc Displacement
;
Leg
;
Magnetic Resonance Imaging
;
Male
;
Prognosis
;
Reflex
;
Retrospective Studies
3.The Usefulness of Endo-rectal Coil MRI in the Staging of Clinically Localized Prostate Cancer.
Eun Tak KIM ; Seong Soo JEON ; Soo Eung CHAI ; Bo Hyun KIM ; Han Yong CHOI
Korean Journal of Urology 2001;42(5):500-505
PURPOSE: We evaluated the ability of endo-rectal coil MRI (ER-MRI) to predict the local pathological stage of prostate cancer prior to radical prostatectomy and compared the results with those of transrectal ultrasonography (TRUS). MATERIALS AND METHODS: ER-MRI using high field magnets (1.5 Tesla) were performed in 22 patients (mean age 62.8 years, range 51-73) with clinically localized prostate cancer before radical prostatectomy. Of the 22 patients, 17 patients were also assessed by TRUS. The results of the imaging techniques were compared with the post-operative histopathological findings. As one patient with pelvic lymph node metastasis, which was detected on frozen-section examination during surgery, was spared radical prostatectomy, the final evaluation included 21 patients. RESULTS: DSeven of the 21 patients (33%) were found to have extraprostatic extension (EPE), and 5 had seminal vesicle invasion (SVI). The sensitivity and specificity for diagnosing EPE using ER-MRI were 62.5% and 84.6%, respectively, and 16.7% and 100% with TRUS. The sensitivity and specificity for diagnosing SVI were 80.0% and 93.8%, respectively with ER-MRI, and 0% and 92.3% with TRUS. The accuracy of predicting SVI was 90.5% with ER-MRI compared to 70.6% with TRUS. CONCLUSIONS: ER-MRI was significantly better than TRUS for determining the local extent of prostatic cancer and for prediction of SVI in the preoperative staging of clinically localized prostate cancer.
Humans
;
Lymph Nodes
;
Magnetic Resonance Imaging*
;
Neoplasm Metastasis
;
Prostate*
;
Prostatectomy
;
Prostatic Neoplasms*
;
Seminal Vesicles
;
Sensitivity and Specificity
;
Ultrasonography
4.A Validation of Dietary Self-Efficacy Questionnaire in Hemodialysis Patients.
Ae Rim SEO ; Ki Soo PARK ; Bo Kyoung KIM ; Yong Lim KIM ; Ji Young CHOI
Korean Journal of Health Promotion 2012;12(1):22-30
BACKGROUND: This study was performed to develop a dietary self-efficacy questionnaire and to determine how dietary self-efficacy is related to selected biochemical markers and health-related quality of life in hemodialysis patients. METHODS: Participants included 172 patients who had been participating in a dialysis program for at least 6 months at two teaching hospitals. A questionnaire was used to assess socio-demographic factors, dialysis-related factors, dietary self-efficacy, and kidney disease quality of life (KDQOL). Serum levels of potassium and phosphorus and interdialytic weight gain were also measured. RESULTS: The internal reliability of dietary self-efficacy was 0.944 (Cronbach's alpha). Principal component analysis resulted in two factors, situational self-efficacy of compliance with dietary guidelines and self-efficacy of food choice. The correlation analysis showed a significant association between situational self-efficacy of compliance with dietary guidelines and serum potassium and KIDQOL. The average scores of situational self-efficacy of compliance with dietary guidelines and self-efficacy of food choice in the participants were 3.52+/-0.72 and 3.61+/-0.71 respectively. Multiple linear regression analysis showed that the situational self-efficacy of compliance with dietary guidelines was significantly associated with serum potassium level and KDQOL and self-efficacy of food choice was significantly associated with KDQOL. CONCLUSIONS: Based on our results, the developed dietary self-efficacy questionnaire may be a suitable survey tool for hemodialysis patients, which can play a role in predicting clinical indicators of patient and health-related quality of life. We recommend further research into clarifying whether the positive effects of increased dietary self-efficacy is maintained in long-term dialysis patients.
Biomarkers
;
Compliance
;
Dialysis
;
Diet
;
Hospitals, Teaching
;
Humans
;
Kidney Diseases
;
Linear Models
;
Phosphorus
;
Potassium
;
Principal Component Analysis
;
Quality of Life
;
Renal Dialysis
;
Self Efficacy
;
Weight Gain
5.Erratum: Pharmacokinetics and bioequivalence of two different 20 mg olmesartan tablets: A randomized, single-dose, two-period crossover study in healthy Korean male volunteers.
Jieon LEE ; Anhye KIM ; Kyung Sang YU ; Jae Yong CHUNG ; Sung Vin YIM ; Bo Hyung KIM
Translational and Clinical Pharmacology 2016;24(2):111-111
In the published version of this article, an error in the sponsor's identity was discovered in the acknowledgment section.
6.A stochastic analysis on the force of infection by hepatitis B virus in Korea.
Keun Young YOO ; Moo Song LEE ; Youngjo LEE ; Bo Youl CHOI ; Heon KIM ; Yong Sik KIM
Korean Journal of Epidemiology 1992;14(2):128-137
No abstract available.
Hepatitis B virus*
;
Hepatitis B*
;
Hepatitis*
;
Korea*
7.A Case of McCunt-Albright Syndrome Associated with Acremegaly and Fibrous Dysplasia.
Jung Guk KIM ; Sung Woo HA ; Sang Won CHUNG ; Seong Mo KOO ; Jae Tae LEE ; Kyu Bo LEE ; Yong Sun KIM ; Sam KWON ; Bo Wan KIM
Journal of Korean Society of Endocrinology 1998;13(1):108-114
Acromegaly and hyperprolactinemia have been described in association with polyostotic fibrous dysplasia. The pathogenic mechanisms of this endocrinopathy are not clear. We experienced a 19-year-old male with hypersecretion of GH, hyperprolactinemia and fibrous dysplasia. He was referred for evaluation of suspected acromegaly. He had no skin pigmentation. Plasma GH, PRL, somatomedin-C, LH, FSH, testosterone, estradiol, progesterone, T3, T4, TSH and cortisol were measured. Among those, the levels of plasma GH, PRL and somatomedin-C were high. Serum alkaline phosphatase was increased. OGTT did not suppress plasma OH concentration and GH showed paradoxical response to TRH and LHRH. GH was suppressed after a test-dose of somatastatin and bromocriptine. Brain MRI demonstrated a mass lesion in sella turcica and another mass lesions in nasal cavity and posterior occipital bone. Whole body bone scan revealed increased uptake in skull, nasal bone, both 9th posterior rib, both femurs, both tibias, left scapular and pelvic bone. These fmdings were consistent with bone tumor such as fibrous dysplasia. We report a case with incomplete MeCune-Albright syndrome including acromegaly, hyperprolactinemia and polyostotic fibrous dysplasia.
Acromegaly
;
Alkaline Phosphatase
;
Brain
;
Bromocriptine
;
Estradiol
;
Femur
;
Fibrous Dysplasia, Polyostotic
;
Glucose Tolerance Test
;
Gonadotropin-Releasing Hormone
;
Humans
;
Hydrocortisone
;
Hyperprolactinemia
;
Magnetic Resonance Imaging
;
Male
;
Nasal Bone
;
Nasal Cavity
;
Occipital Bone
;
Pelvic Bones
;
Plasma
;
Progesterone
;
Ribs
;
Sella Turcica
;
Skin Pigmentation
;
Skull
;
Testosterone
;
Tibia
;
Young Adult
8.A Case of Relapsed Lepromatous Leprosy Misdiagnosed as Granuloma Faciale.
Yong Se CHO ; Jee Hee SON ; Yunsun BYUN ; Bo Young CHUNG ; Hyeone KIM ; Chun Wook PARK
Korean Journal of Dermatology 2017;55(3):215-217
No abstract available.
Granuloma*
;
Leprosy, Lepromatous*
9.Two Cases of Congenital Chylothorax Diagnosed by Prenatal Ultrasonography.
Kyung Hyun CHUNG ; Wan CHO ; Man Yong HAN ; Bo Kyung KIM ; Kyu Hyung LEE
Korean Journal of Perinatology 1999;10(4):512-517
Congenital chylothorax is a rare disorder and can be diagnosed by prenatal ultrasonography recently. Most cases of congenital chylothorax were characterized by different clinical courses of respiratory distress. We describe two female cases with congenital chylothorax observed by ultra- sonography prenatally. In the first case, left-sided pleural effusion was noted by prenatal ultrasonography taken at 34 weeks of gestation, and then pleural fluid was extracted by intrauterine thoracentesis under sonography guidance. After birth, this patient was managed by TPN(total parentral nutrition) and intermittent thoracentesis without surgical treatment. But, pleural fluid was accumulated recurrently and respiratory distress was aggravated. At 15th hospital day, shock state was developed and patient died. In the second case, bilateral pleural effusion and ascites were noted by prenatal ultrasonography, and then patient was delivered immediately without intrauterine thoracentesis. After birth, the second case received conservative therapy including mechanical ventilation, TPN, intermittent thoracentesis and paracentesis. The patient was discharged with complete regression of chylothorax. We report the two cases with brief review of related literatures.
Ascites
;
Chylothorax*
;
Female
;
Humans
;
Paracentesis
;
Parturition
;
Pleural Effusion
;
Pregnancy
;
Respiration, Artificial
;
Shock
;
Ultrasonography, Prenatal*
10.Two Cases of Hemolytic Disease of the Newbom due to Anti-E Antibody in Sisters.
Sang Woo KIM ; Jung Ho LEE ; Yong Won PARK ; Bo Moon SIN
Korean Journal of Blood Transfusion 1995;6(2):193-200
Isoimmune hemolytic disease of the newborn due to anti-E is a disease characterized by the progressive neonatal hyperbilimbinemia and anemia which is caused by the IgG antibody transmitted from the mother to the ferns. Authors have experienced two cases of isoimmune hemolytic disease due to anti-E, who presented with jaundice on the first and the second day of life, respectively. The ABO and Rh blood types of their mother and father were B, CcDee and O, ccDEE, respectively. Both babies showed positive direct Coombs test and the mother showed strong positive indirect Coombs test. Antibody identification tests were made only in the first case and the mother, both of which revealed anti-E antibody. The first case was treated with phototherapy for 3 days and two blood transfusions. The second case was treated with phototherapy for 6 days and two exchange transfusions.
Anemia
;
Blood Transfusion
;
Coombs Test
;
Fathers
;
Ferns
;
Humans
;
Immunoglobulin G
;
Infant, Newborn
;
Jaundice
;
Mothers
;
Phototherapy
;
Siblings*