1.Chlorophyll derivatives (CpD) extracted from silk worm excreta are specifically cytotoxic to tumor cells in vitro.
Won Young LEE ; Jeon Han PARK ; Byung Soo KIM ; Man Jung HAN ; Bo Sop HAHN
Yonsei Medical Journal 1990;31(3):225-233
Animal
;
Antineoplastic Agents, Phytogenic/isolation & purification/*pharmacology
;
Chlorophyll/*analogs & derivatives/isolation & purification/pharmacology/radiation effects
;
Comparative Study
;
Drug Screening Assays, Antitumor
;
Feces/*chemistry
;
Hematoporphyrin Derivative
;
Hematoporphyrins/pharmacology
;
Human
;
Leukocytes, Mononuclear/drug effects
;
Mice
;
Oxygen/metabolism
;
Photochemistry
;
Photochemotherapy
;
Radiation-Sensitizing Agents/isolation & purification/*pharmacology
;
Silkworms/*metabolism
;
Singlet Oxygen
;
Spectrophotometry
;
Structure-Activity Relationship
;
Support, Non-U.S. Gov't
;
Tumor Cells, Cultured/*drug effects/radiation effects