1.Efficacy and Safety of Matrix Shave Biopsy Using a Razor Blade for the Diagnosis of Longitudinal Melanonychia
Bo Ra LIM ; Kang Hyun CHO ; Kun PARK
Korean Journal of Dermatology 2021;59(1):38-44
Background:
Longitudinal melanonychia (LM) can be caused by a variety of benign and malignant conditions. Nail matrix biopsy is necessary for the diagnosis of LM; however, physicians hesitate to perform the nail matrix biopsy due to the risk of postoperative complications like permanent matrix damage. Therefore, biopsy methods that minimize the risk of postoperative complications are necessary.
Objective:
To investigate the efficacy and safety of the nail matrix shave biopsy using a razor blade.
Methods:
We reviewed the medical records, clinical photographs, and histopathologic slides of patients who underwent shave biopsy for the diagnosis of LM from January 2018 to March 2020 at Wonkwang University Hospital.
Results:
The entire pigmented lesion was removed completely by shaving only a partial thickness of the superficial matrix in all patients. The histopathologic diagnosis was melanocyte activation with no atypia in all cases. Eight patients were followed up for 7∼19 months. Resting pain after the shave biopsy improved in most cases (75%) within 1 week. One patient experienced numbness lasting for 3 months. Abnormal sensations, such as tingling and itching, were temporarily reported by two patients. One patient (12.5%) had temporary postoperative nail plate dystrophy, and three patients (37.5%) had recurrence of pigmentation.
Conclusion
Our protocol of shave biopsy showed a lower rate of postoperative nail dystrophy than the conventional shave biopsy. We suggest that the shave biopsy using a flexible stainless steel razor blade is a favorable alternative to the conventional shave biopsy.
2.A Case of Liposclerosing Granuloma Arising from Lower Eyelid.
Journal of the Korean Society of Plastic and Reconstructive Surgeons 2008;35(5):603-606
PURPOSE: Sclerosing lipogranuloma is an unusal benign condition of the genitalia following injections into the genitalia with exogenous paraffin or mineral oil. A few cases have been reported in which sclerosing lipogranuloma of the lid was caused by paraffin- containing ointment plugs after the endonasal sinus surgery. A 52-year-old man presented with a painless hard mass of the right lower lid after the MRI scan at the Ophthalmology department. Nine months before, he had undergone right maxilla sinus surgery through the oral incision. And he was also gotten nasal packing with Vaseline gauze after the surgery. METHODS: The round shaped two masses in the Right lower lid were approximately 1.0x1.0cm in size. There were no size or color change, bleeding and ulceration. The MRI scan showed a suspicious part of an abscess of benign tumor. Also, He was planned cyst remove through the endonasal surgery due to the mucoid cyst in the right maxillary sinus in the ENT dept. Under the general anesthesia, the patient underwent surgical excision through a subcilliary incision with endonasal sinus surgery. The masses were in deep subcutaneous orbital fat with no connection with right maxillary sinus. RESULTS: The masses were excised 2.1x0.7cm in size including surrounding necrotic fatty tissue. Histopathological diagnosis was 'sclerosing lipogranuloma' due to paraffin or similar substance with fat necrosis and cystic change. This tissue was positive in PAS, S-100, CD68 reaction. CONCLUSION: It is extremely rare to find a granulomatous orbital lesion arising to a endonasal surgery. In conclusion, if sclerosing lipogranuloma is suspected excisional biopsy should be undertaken. Surgery should be reserved for recurrent or refractory cases when steroids have failed as first-line treatment at the 6-month follow-up examination, There was no complication or recurrence.
Abscess
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Adipose Tissue
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Anesthesia, General
;
Biopsy
;
Eyelids
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Fat Necrosis
;
Follow-Up Studies
;
Genitalia
;
Granuloma
;
Hemorrhage
;
Humans
;
Magnetic Resonance Imaging
;
Maxilla
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Maxillary Sinus
;
Middle Aged
;
Mineral Oil
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Ophthalmology
;
Orbit
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Paraffin
;
Petrolatum
;
Recurrence
;
Steroids
;
Ulcer
3.Syringomyelia Associated with Posterior Fossa Tumor: Case Report.
Bo Ra SEO ; Shin JUNG ; Sam Suk KANG
Journal of Korean Neurosurgical Society 2003;33(5):521-524
The authors describe three patients of syringomyelia associated with posterior fossa tumor. The lesions were diagnosed by magnetic resonance imaging. Total removal of tumor without decompression of foramen magnum was done and regression of syringomyelia and improvement of symptoms were demonstrated. It is suggested that the blockage of cerebrospinal fluid flow at the foramen magnum by tonsilar herniation may play an important role in syrinx formation.
Cerebrospinal Fluid
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Decompression
;
Foramen Magnum
;
Humans
;
Infratentorial Neoplasms*
;
Magnetic Resonance Imaging
;
Syringomyelia*
4.Tumoral Calcinosis on the Dorsal Aspect of the Wrist Presenting as a Deep-seated Nodule
Hong Je KANG ; Keon Rok KIM ; Bo Ra LIM ; Kun PARK
Korean Journal of Dermatology 2021;59(3):225-228
Tumoral calcinosis is an ectopic calcification syndrome characterized by an irregular soft tissue mass. It has been reported mainly in large joints such as the hip, shoulder, knee, and elbow, but rarely in the hands. When it occurs on the dorsal side of the wrist, there are no specific symptoms except for localized tenderness. Therefore, it is difficult to differentiate the calcification from other common hand tumors, especially ganglions. We report a case of tumoral calcinosis that occurred on the dorsal side of the wrist with magnetic resonance imaging findings.
5.Tumoral Calcinosis on the Dorsal Aspect of the Wrist Presenting as a Deep-seated Nodule
Hong Je KANG ; Keon Rok KIM ; Bo Ra LIM ; Kun PARK
Korean Journal of Dermatology 2021;59(3):225-228
Tumoral calcinosis is an ectopic calcification syndrome characterized by an irregular soft tissue mass. It has been reported mainly in large joints such as the hip, shoulder, knee, and elbow, but rarely in the hands. When it occurs on the dorsal side of the wrist, there are no specific symptoms except for localized tenderness. Therefore, it is difficult to differentiate the calcification from other common hand tumors, especially ganglions. We report a case of tumoral calcinosis that occurred on the dorsal side of the wrist with magnetic resonance imaging findings.
6.Clinical characteristics of adverse reaction to radiocontrast media in children - A single center experience.
Min Jung KIM ; Bo Ra LEE ; Young Hun CHOI ; Dong Yoon KANG ; Hye Ryun KANG ; Dong In SUH
Allergy, Asthma & Respiratory Disease 2018;6(6):315-321
PURPOSE: Radiocontrast media are widely used in medical imaging to improve diagnostic accuracy. However, studies on the adverse reactions of radiocontrast media in children are limited. We aimed to describe the characteristics of adverse reactions to radiocontrast media among children who had a computed tomography scan or magnetic resonance imaging in a tertiary university hospital. METHODS: We retrospectively collected data on adverse reactions to radiocontrast media by the reporting system of a tertiary university hospital. We selected data from children under the age of 19 from July 2011 to December 2017 and analyzed their characteristics. We focused mainly on the characteristics of the index case which is defined by the first adverse event of each subject. RESULTS: During the period, a total of 88,050 radiocontrast media-enhanced imaging studies were performed and 184 cases of adverse reactions were reported. A total of 71 were identified as index cases. Forty-nine (69.0%) were male and the mean age was 12.7±3.2 years. The incidence of radiocontrast media-related adverse reactions was 0.09% and severe reactions were 0.002%. The most common clinical feature was skin manifestations (54.9%), followed by gastrointestinal symptoms (40.8%) and neuropsychiatric symptoms (7.4%). CONCLUSION: Adverse reactions to radiocontrast media rarely occur in children and the incidence of severe reactions is low. Most reactions are mild and are related to the skin and gastrointestinal system. This report would provide good evidence for establishing a management strategy in children scheduled for imaging studies using radiocontrast media.
Child*
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Contrast Media*
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Diagnostic Imaging
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Humans
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Incidence
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Magnetic Resonance Imaging
;
Male
;
Retrospective Studies
;
Skin
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Skin Manifestations
7.Development of the Korean Affective Word List.
Bo Ra KIM ; Eun LEE ; Hyang Hee KIM ; Jin Young PARK ; Jee In KANG ; Suk Kyoon AN
Journal of Korean Neuropsychiatric Association 2010;49(5):468-479
OBJECTIVES: As interest in the field of affective science continues to increase, research into the arousal of emotions by the use of facial stimuli, event pictures, and stimulus words is now being actively pursued. The purpose of this study was to develop a Korean Affective Word List for eliciting emotional reactions. METHODS: The preliminary selection process was more carefully divided into the primary process when the words were extracted which the author thought elicited the emotions of happiness, sadness, fear, anger, and disgust from the Korean-Language Dictionary according to vocabulary frequency, the secondary process when the words were extracted which the Affective Words Selection Committee judged elicited only a single category of emotion. The affective words selected in the two-stage preliminary process were then presented to normal, young subjects, who were asked to allocate each word on the basis of their emotional reaction to one of the following emotional categories: happiness, sadness, fear, anger, disgust, and surprise. After the selected words caused the intended-emotional response with inter-rater agreement in more than 80%, a total of 166 words were selected except surprise. The complementary selection process was carried out following the preliminary process in order to make up for the lack of surprise words and the relative want of anger words. RESULTS: A total of 184 words were finally selected: 83 words for happiness, 36 for sadness, 24 for fear, 10 for anger, 20 for disgust, and 11 for surprise. CONCLUSION: These Korean affective words are expected to be widely used for eliciting emotions in future Korean research on emotion.
Anger
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Arousal
;
Happiness
;
Vocabulary
8.The Legal Doctrine on 'Limitation of Liability' in the Precedent Analysis on Plastic Surgery Medical Malpractice Lawsuits.
Bo Young PARK ; Ji Hyun PAK ; Seung Eun HONG ; So Ra KANG
Journal of Korean Medical Science 2015;30(12):1718-1722
This study intended to review the precedents on plastic surgery medical malpractice lawsuits in lower-court trials, classify the reasons of 'limitation of liability' by type, and suggest a standard in the acknowledgement of limitation of liability ratio. The 30 lower-court's rulings on the cases bearing the medical negligence of the defendants acknowledged the liability ratio of the defendants between 30% and 100%. Ten cases ruled that the defendants were wholly responsible for the negligence or malpractice, while 20 cases acknowledged the limitation of liability principle. In the determination of damage compensation amount, the court considered the cause of the victim side, which contributed in the occurrence of the damage. The court also believed that it is against the idea of fairness to have the assailant pay the whole compensation, even there is no victim-side cause such as previous illness or physical constitution of the patient, and applies the legal doctrine on limitation of liability, which is an independent damage compensation adjustment system. Most of the rulings also limited the ratio of responsibility to certain extent. When considering that the legal doctrine on limitation of liability which supports concrete validity for the fair sharing of damage, the tangible classification of causes of limitation of liability suggested in this study would be a useful tool in forecasting the ruling of a plastic surgery medical malpractice lawsuit.
Humans
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*Liability, Legal
;
Malpractice/*legislation & jurisprudence
;
Reconstructive Surgical Procedures/adverse effects/legislation & jurisprudence
;
Republic of Korea
;
Surgery, Plastic/*adverse effects/*legislation & jurisprudence
9.Sex Differences in Remifentanil Requirements for Preventing Cough during Anesthetic Emergence.
Sarah SOH ; Wyun Kon PARK ; Sang Wook KANG ; Bo Ra LEE ; Jeong Rim LEE
Yonsei Medical Journal 2014;55(3):807-814
PURPOSE: Target-controlled infusion (TCI) of remifentanil can suppress coughing during emergence from general anesthesia; nevertheless, previous studies under different clinical conditions recommend significantly different effective effect-site concentrations (effective Ce) of remifentanil for 50% of patients (EC50). The differences among these studies include type of surgery and patient sex. In recent years, study of sex differences in regards to anesthetic pharmacology has drawn greater interest. Accordingly, we attempted to determine the effective Ce of remifentanil for preventing cough for each sex under the same clinical conditions. MATERIALS AND METHODS: Twenty female and 25 male ASA physical status I-II grade patients between the ages of 20 and 46 years who were undergoing thyroidectomy were enrolled in this study. The effective Ce of remifentanil for preventing cough was determined for each sex using the isotonic regression method with a bootstrapping approach, following Dixon's up-and-down method. RESULTS: Isotonic regression with a bootstrapping approach revealed that the estimated EC50 of remifentanil for preventing coughing during emergence was significantly lower in females {1.30 ng/mL [83% confidence interval (CI), 1.20-1.47 ng/mL]} than in males [2.57 ng/mL (83% CI, 2.45-2.70 ng/mL)]. Mean EC50 in females was also significantly lower than in males (1.23+/-0.21 ng/mL vs. 2.43+/-0.21 ng/mL, p<0.001). Mean arterial pressure, heart rate, and respiratory rate over time were not significantly different between the sexes. CONCLUSION: When using remifentanil TCI for cough prevention during anesthetic emergence, patient sex should be a considered for appropriate dosing.
Adult
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Anesthesia, General/*adverse effects
;
Cough/*prevention & control
;
Female
;
Humans
;
Male
;
Middle Aged
;
Piperidines/*administration & dosage/*therapeutic use
;
Sex Factors
;
Young Adult
10.Long-term Follow-Up of Recurred Adenoid Cystic Carcinoma of the Scalp.
Bo Young PARK ; Yang Woo KIM ; So Ra KANG
Journal of the Korean Society of Plastic and Reconstructive Surgeons 2009;36(4):507-510
PURPOSE: Adenoid cystic carcinoma (ACC) is a rare malignant epithelial neoplasm derived from the salivary glands. In some cases, ACC may arise in other primary sites, such as skin. We report a case of adenoid cystic carcinoma arising the scalp skin of a 69-year-old woman. METHODS: A 69-year-old woman presented with a tender scalp nodule. A local wide excision was performed. Histopathologic examination revealed the adenoid cystic carcinoma with basaloid cells in a cribriform pattern. The resection margins were free of tumor. Two years later a tumor recurred in the scarred area. The lesion was removed surgically and the histopathological diagnosis of adenoid cystic carcinoma was again established. After two years, tumor recurred again and distant metastasis of the lung was diagnosed. A surgical wide excision was done and the close regular follow-up for recurrence was done. Two years later, third recurrence of the scalp was observed. We also performed the wide local excision with tumor free margin. RESULTS: We experience the recurrent adenoid cystic carcinoma of the scalp with pulmonary metastasis. We have performed the wide local excision for three times. The patient has been followed up for 10 years with regular work-up for recurrence and metastasis CONCLUSION: primary cutaneous adenoid cystic carcinoma is a rare skin neoplasm with a high potential for recurrence after local excision. The standard treatment of ACC is wide local excision with tumor-free margins established by permanent section.
Adenoids
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Aged
;
Carcinoma
;
Carcinoma, Adenoid Cystic
;
Cicatrix
;
Female
;
Follow-Up Studies
;
Humans
;
Lung
;
Neoplasm Metastasis
;
Recurrence
;
Salivary Glands
;
Scalp
;
Skin
;
Skin Neoplasms