1.Effects of angiotensin Ⅳ on growth of cultured neonatal rat cardiomyocytes
Chinese Journal of Pathophysiology 1989;0(05):-
AIM: To study the effects of angiotensin Ⅳ(Ang Ⅳ) on growth of cultured neonatal rat cardiomyocytes.METHODS: Cardiomyocytes isolated from neonatal SD rat were cultured in vitro and divided into groups: control DMEM,10~(-6) mol/L Ang Ⅳ, 10~(-5) mol/L Ang Ⅳ.The effects of Ang Ⅳ were assayed as follows: protein synthesis was determined by modified Bradford method,and cell cycle by flow cytometry.RESULTS: Ang Ⅳ promoted protein synthesis(P
6.Study on Pathogenesis of Complex Syndrome of Functional Gastrointestinal Disorders in 72 cases
Journal of Traditional Chinese Medicine 1993;0(06):-
Objective:To probe distribution law and pathogenesis of TCM complex symptoms of functional dyspepsia and irritable bowel syndrome.Methods:Generally recognized criteria was to establish database of comprehensive analysis of the data gained by the four methods of diagnosis,and analyze with SPSS8.0.Results:Syndrome distribution was most closely related with spleen deficiency,accounting for 66.7%;and the next,with stagnation of liver-Qi,accounting for 40.3%;the last,with the kidney,only accounting for 5.6%.Conclusion:Cause of disease and inducing factors of this disease are closely correlated with pathogenic cold, diet of lipids,mental depression,prolonged disease,wound due to abdominal operation.The disease is located at the stomach, intestine with most coexistence of deficiency and excess,and spleen deficiency is the key of pathogenesis.
7.The relationship between osteopontin plasma concentration and disease activity in systemic lupus erythematosus
Bo LOU ; Jing LU ; Min ZHENG ;
Chinese Journal of Dermatology 1994;0(06):-
Objective To investigate the relationship between plasma concentration of osteopontin (OPN) and disease activity in systemic lupus erythematosus (SLE).Methods The plasma concentration of OPN in 28 healthy controls and 38 SLE patients was measured by enzyme-linked immunosorbent assay. Results The plasma concentration of OPN was significantly higher in SLE patients compared to that in the healthy controls (420?203 ng/mL vs 73?14 ng/mL,P<0.001),in the patients with proteinuria com- pared to that in the patients without proteinuria (623?88 ng/mL vs 288?135 ng/mL,P<0.001),in the patients with active disease compared to that in those with inactive disease (529?143 ng/mL vs 185?66ng/mL,P<0.001),in the patients before treatment compared to that in the patients after treatment (556?130 ng/mL vs 142?22 ng/mL,P<0.001).The plasma concentration of OPN in patients with arthritis was not different from those without arthritis (489?153 ng/mL vs 375?222 ng/mL,P>0.05).Plasma concentration of OPN showed a significant positive correlation with systemic lupus erythematosus disease ac- tivity index (SLEDAI) (r=0.93,P<0.001),but a significant negative correlation with serum C3 level (r=-0.49,P<0.05).There was no correlation between plasma concentration of OPN and antinuclear an- tibody titre,erythrocyte sedimentation rate,or serum level of C4.Conclusions These data show that plas- ma OPN level has some correlation with the SLE activity,renal damage and progression or amelioration of SLE.OPN could be involved in the pathogenesis of SLE.
8.Cathepsin S and atherosclerosis
Min ZHANG ; Yamin LIU ; Bo ZHANG
International Journal of Cerebrovascular Diseases 2013;(1):55-58
Cathepsin S is one of the cathepsins that distributes generally at lysosomes of histiocyte in humans body.It has variety of actions when it is unbalancing,including promote inflammation,atherosclerosis,diabetes and obesity,etc.Studies in recent years have demonstrated that there are certain correlations of adiponectin with vascular risk factor and cerebrovascular disease.
9.The exploration of teaching model in anesthesia training for standardized training residents
Chinese Journal of Medical Education Research 2011;10(4):459-461
Anesthesia related skills training is an important component of standardized residency training plan.Attention should be paid to the clinical thinking ability,preoperative assessment capacity,sterile concepts and technologies,cardiopulmonary brain recovery skills and teamwork ability cultivation during the rotation of resident physieians and resident surgeons,and comprehensive and scientific examination system should be established
10.The establishment of audio medical English terminology corpus and its use in the terminology teaching to medical students
Fengxiang LU ; Bo YANG ; Nan MIN
Chinese Journal of Medical Education Research 2011;10(12):1511-1513
Medical students should study and enlarge their medical terminology from their medical English courses as well as bilingual courses. This ability is a key part in the cultivation of high-levelled medical talents.However,medical words are special from general English in three parts:long,great in numbers and difficult to read.These characteristics leave the medical students in a hard situation in their promotion of medical terminology.If the students are provided and guided with a convenient and efficient software based on modem education technology,they can achieve much better results.The audio medical English terminology corpus can help the medical students achieve their goal in promotion of medical termi-nology.