PURPOSE: To evaluate the clinical characteristic of retinal nerve fiber layer (RNFL) and The clinical types of glaucoma according to optic disc appearances. METHODS: Sixty eyes in 60 patients with glaucoma were evaluated retrospectively. Complete ophthalmologic examination, optical coherent tomography (OCT), automated perimetry, stereoscopic optic disc photography and RNFL photography were performed. We classified optic disc pattern into focal, myopic, generalized enlargement, senile sclerotic, and normal appearance types. RESULTS: In 60 eyes with glaucoma, 15 eyes were adult-onset primary open-angle glaucoma (Adult-onset POAG), 22 eyes were normal-tension glaucoma (NTG), 10 eyes were juvenile-onset open-angle glaucoma (JPOAG), and 13 eyes were secondary glaucoma. JPOAG patients were significantly more detected in association with myopic optic disc type (P<0.05). OCT- measured temporal RNFL thickness in focal optic disc pattern were significantly lower than that in myopic optic disc pattern (P<0.05). Age was significantly correlated with temporal RNFL thickness in our study subjects (P<0.036, r=-0.272). CONCLUSIONS: Our study revealed that JPOAG patients may have a relationship with myopic optic disc type. OCT-measured RNFL thickness of glaucoma patients particularly in the temporal quadrant may be related to age.
Glaucoma ; Glaucoma, Open-Angle ; Humans ; Nerve Fibers* ; Photography ; Retinaldehyde* ; Retrospective Studies ; Visual Field Tests

PURPOSE: To evaluate the results of interlocking humeral nail for femur shaft fractures through the greater trochanter in older children and adolescent. MATERIALS AND METHODS: Eleven femoral shaft fractures in ten patients were selected. They were consisted of 9 boys and 1 girl. Two patients had osteogenesis imperfecta and one patient had a simple bone cyst as an underlying disease. 7 cases were right side and 4 cases were left side. The mean age at the time of operation was 12 years and 7 months (8 years 11 months~15 years 7 months). The mean follow-up period was 21 months and interlocking humeral nail was inserted at the greater trochanter in all patients. RESULTS: All patients had a complete bony union without any complication such as infection, nonunion, leg length discrepancy and metal failure. Avascular necrosis of femoral head and coxa valga were not developed in all patients. CONCLUSION: Intramedullary nailing through the greater trochanter using interlocking humeral nail is effective and safe treatment for the femoral shaft fracture in older children and adolescents.
Adolescent ; Bone Cysts ; Child ; Coxa Valga ; Femur ; Follow-Up Studies ; Fracture Fixation, Intramedullary ; Head ; Humans ; Leg ; Nails ; Necrosis ; Osteogenesis Imperfecta

BACKGROUND: There are no reports of the pressure changes across the foot after extraarticular subtalar arthrodesis for a planovalgus foot deformity in cerebral palsy. This paper reviews our results of extraarticular subtalar arthrodesis using a cannulated screw and cancellous bone graft. METHODS: Fifty planovalgus feet in 30 patients with spastic diplegia were included. The mean age at the time of surgery was 9 years, and the mean follow-up period was 3 years. The radiographic, gait, and dynamic foot pressure changes after surgery were investigated. RESULTS: All patients showed union and no recurrence of the deformity. Correction of the abduction of the forefoot, subluxation of the talonavicular joint, and the hindfoot valgus was confirmed radiographically. However, the calcaneal pitch was not improved significantly after surgery. Peak dorsiflexion of the ankle during the stance phase was increased after surgery, and the peak plantarflexion at push off was decreased. The peak ankle plantar flexion moment and power were also decreased. Postoperative elevation of the medial longitudinal arch was expressed as a decreased relative vertical impulse of the medial midfoot and an increased relative vertical impulse (RVI) of the lateral midfoot. However, the lower than normal RVI of the 1st and 2nd metatarsal head after surgery suggested uncorrected forefoot supination. The anteroposterior and lateral paths of the center of pressure were improved postoperatively. CONCLUSIONS: Our experience suggests that the index operation reliably corrects the hindfoot valgus in patients with spastic diplegia. Although the operation corrects the plantar flexion of the talus, it does not necessarily correct the plantarflexed calcaneus and forefoot supination. However, these findings are short-term and longer term observations will be needed.
Adolescent ; Arthrodesis/*methods ; Bone Screws ; Bone Transplantation ; Cerebral Palsy/*complications ; Child ; Child, Preschool ; Female ; Flatfoot/etiology/radiography/*surgery ; Foot/radiography ; Foot Deformities, Acquired/etiology/*surgery ; Humans ; Leg ; Male ; Muscle Spasticity/complications ; Muscle, Skeletal/surgery ; Postoperative Complications ; Subtalar Joint/radiography/surgery ; Walking/physiology

OBJECTIVES: We investigated the characteristics of P300 generators in obsessive-compulsive disorder(OCD) patients by using voxel-based statistical parametric mapping of current density images. METHODS: P300 generators, produced by a rare target tone of 1500Hz under a frequent non-target tone of 1,000Hz, were measured in 15 right-handed OCD patients and 15 controls. Low Resolution Electromagnetic Tomography(LORETA), using a realistic head model of the boundary element method based on individual MRI, was applied to the 128-channel EEG. Statistical parametric mapping(SPM) was applied for the statistical analysis. RESULTS: We found that both groups had the mean current density of P300 in the parietal, temporal and prefrontal lobe. There was a trend for decreased current density in the prefrontal area in OCD patients. The statistical comparison showed current density increase in the supraparietal area, a statistically significant longer P300 latency and a trend for reduced P300 amplitude in OCD patients. CONCLUSION: It suggests that P300 source of both groups exists in multiple brain regions at the same time. And both groups had no statistically significant differences in the current density of P300 except for increased current density in the supraparietal area in OCD patients. But, considering the statistically significant longer P300 latency, a trend for reduced P300 amplitude and relative mean current density reduction in the prefrontal area in OCD patients, this study suggests that the frontal lobe may have a reduced normal inhibitory process in OCD patients.
Brain ; Electroencephalography ; Frontal Lobe ; Head ; Humans ; Insulator Elements ; Magnetic Resonance Imaging ; Magnets ; Obsessive-Compulsive Disorder* ; Rabeprazole