Objective To discuss the mechanism of growth hormone (GH) in infection and its safety. Methods Advances in the application of GH in infection of recent years were reviewed. Results In infectious patients, GH may promote protein synthesis, strengthen the immunity of body, and protect the integrity of intestinal barrier function. But some patients present GH resistance. The safety of GH for infectious patients needs further evaluation. Conclusion GH may play a supplementary role in infection therapy, but further research is needed.

Objective To explore the anxious condition of nurses and correlative factors,and to explore the relationship between the nurses' anxiety and the correlative factors,so that can help the management echelon and nurses to correctly understand the relationship of anxiety and pressure,and control and handle the anxiety problem of nurses fundamentally,and improve the physical and mental health,work efficiency and nursing quality of nurses. Methods A questionnaire investigation was conducted in 85 nurses from a certain hospital in Harbin about the anxiety,life events,work stressor and the relationship between them. Results 30 nurses had anxiety(the anxiety group),another 55 nurses showed no anxiety(the nonanxiety group).The comparison of items in life events inventory showed that great difference existed in pregnancy,addition of new family members,the difficulty of training their children,property damage or being stolen,living apart with the spouse,magnificent changes of the life style,having got severe illness or wound.In the aspect of work sttessor scale,professional and career issues,workload and allocation of time,working environment,patient care and interaction showed significant difference.The work pressure was significantly associated with the level of anxiety. Conclusions Our finding suggest that effective stress management strategies should be implemented to reduce or eliminate work pressure of nurses,carry out training to improve the self-regulation ability of nurses,and if necessary biofeedback therapy can be introduced.

Objective To discuss the systematic training method for new nurses in central sterile supply department(CSSD),in order to improve the training effects of new nurses and special practice ability,and make them to be qualified for jobs in CSSD.Methods 18 new nurses in CSSD were divided into the control group and the experimental group with 9 nurses in each group.The experimental group adopted systematic training method combining with unit tests and comprehensive evaluation.The control group chose the traditional training method.The testing results were compared between two groups.Results The experimental group all passed through the unit evaluation and comprehensive evaluation,could work independently after the training,got excellent achievement in comprehensive assessment of the department after 3 months on-the-job,and could finish all the work and solve various emergencies.4 passengers failed in unit assessment in the control group,and 3 failed in the comprehensive evaluation.The average results in the experimental group were obviously higher than that of the control group.Conclusions Scientific training content,the systematic training method,comprehensive evaluation method can avoid the blindness and arbitrariness in training and improve training effect.The implementation of unit access system and post access system in standardized training of new nurses can improve the study enthusiasm and strengthen the risk and responsibility consciousness of nurses,which is beneficial to the growth of new nurses and professional value guidance.

The physical and chemical factors affecting the allergenic potency of the house bdust mite Dermatophagoides farinae extract were determined by skin test and ELISA technique in the asthmatic patients sensitive to the mite. The results showed that the allergenic potency of the extract could be reduced by heat sterilization, trypsin trea-tment and lyophization,but not lost completely,and that the potency could be increasedby supersonic treatment and repeated freeze-thaw(but less than 10 times).It was alsoshowed that the allergenic potency of the extract preserved at -20℃ was more stablethan those preserved at 4℃ or at room temperature,and that the mite extract preservedat 4℃ more than 9 years still had allergenic potency.

Neural stem cells which have many characters of high self-renewal, multipotentiality, migration and good histocompatibility could differentiate neurons, astrocyte and oligodendrocyte. Therefore, the research on differentiation mechanisms of neural stem cells should be very important for the therapy of nervous system degenerative diseases and functional recovery of the central nervous system injury. The neural stem cells differentiation mechanisms regulated by the genes and environment were reviewed in the present paper.

BACKGROUND: Hydrofluoric acid burns are occuring with ever-increiisir g frequency due to the wide use of this acid in industrial fields, such as electronics and semiconductor i idustries. OBJECTIVE: The purpose of thie study was to evaluate the clinical charateristics of hydrofluoric acid burn. This study will give basic information of hydrofluoric acid burn to the dermatologists who are not familiar with hydrofluoric acid. METHOD: Twenty-two patient who were diagnosed as having hydroiluiiric acid burns at koryo General Hospital(1986-1993) were irraluated clinical)y. Forteen were malc ar d eight were female, most of them were in their third decade. RESULTS: The results are sumrnurised as follows 1. Latent periods were variabie from 30 min. to 3 days. Most patients recognized their chemical burn several hours after exposure. 2. Foot & sole (9 cases) and fingers (7 cases) were most frequently in olved. In 7 cases, nails were also involved. 3. Pain was the most. commori iuobjective symptom. 4. Skin lesions showed erytherna, erythematous swelling, erosion, bulla., necrosis, pigmentation and crust, formation, progressii ely. 5. Treatment Wet dressing with Hyami-solution and topical application of ai tibiotics or steroidointment were sufficient in mild case. In severe cases, intralesional injection of calcium glucoante was perfirmed. Debridement was also performed after the progn ssion of tissue damage stopped. Nails were extracted in cases involving nails. CONCLUSION: Hydrofluoric acid burn is characterized clinically by severc progessive tissue destruction and excruciating pain. Dermatologists need to be aware of the clinical features of hydroclucric acid burn and its proper treatment.
Bandages ; Burns* ; Burns, Chemical ; Calcium ; Debridement ; Female ; Fingers ; Foot ; Humans ; Hydrofluoric Acid* ; Injections, Intralesional ; Necrosis ; Pigmentation ; Semiconductors ; Skin

Animals ; Drugs, Chinese Herbal ; pharmacology ; Enzyme Activation ; Humans ; Medicine, Chinese Traditional ; NF-kappa B ; antagonists & inhibitors ; genetics ; metabolism ; Promoter Regions, Genetic ; Signal Transduction ; drug effects ; Transcription, Genetic ; genetics ; Transcriptional Activation ; genetics

Administration, Oral ; Adolescent ; Female ; Histiocytosis, Langerhans-Cell ; complications ; drug therapy ; pathology ; Humans ; Lymph Nodes ; pathology ; Prednisone ; administration & dosage ; therapeutic use ; Retrospective Studies ; Skin Ulcer ; drug therapy ; etiology ; pathology ; Thalidomide ; administration & dosage ; therapeutic use ; Treatment Outcome

OBJECTIVETo observe the acupoint distribution and clinical efficacy of lumbar disc herniationi (LDH) with different sensitive types.

METHODSEighty patients with LDH were randomly divided into a heat-sensitive moxibustion group (group A), a heat-sensitive acupuncture group (group B), a force-sensitive acupuncture group (group C) and a force-sensitive moxibustion group (group D), 20 cases in each one. In the group A and the group B, moxibustion and acupuncture were applied at two or three heat-sensitive acupoints separately. In the group C and the group D,acupuncture and moxibustion were used at two or three force-sensitive acupoints respectively. The treatment was given once a day, totally 10 times. The distribution law of the heat-sensitive acupoints and the force-sensitive acupoints and the change of M-JOA before and after treatment were recorded in the four groups.

RESULTSThe frequent heat-sensitive acupoints areas of LDH were at Yaoyangguan (GV 3), Dachangshu (BL 25), Zhiyang(GV 9), Guanyuanshu(BL 26) and Weizhong(BL 40). The major force-sensitive acupoints areas were at Shenshu (BL 23), Dachangshu (BL 25), Tianshu (ST 25), Guilai (ST 29) and Weizhong (BL 40). After treatment, the heat-sensitive acupoints in the group A and the group B were all reduced than those before treatment and the force-sensitive acupoints in the group C and the group D were declined as well (P < 0.01, P < 0.05). The M-JOA scores were obviously lower than those before treatment in the four groups (all P < 0.01). The score in the group A was reduced more apparently than that in the group B (P < 0.05). The score in the group C was declined more markedly than that in the group D (P < 0.05).

CONCLUSIONThere are diverse acupoints for LDH patients due to different sensitive types. All forms of stimulation can change the functional state of acupoints. Moxibustion is more suitable for heat-sensitive acupoints and acupuncture is optimal for force-sensitive acupoints.

Acupuncture Points ; Acupuncture Therapy ; methods ; Adult ; Aged ; Female ; Humans ; Intervertebral Disc Displacement ; therapy ; Male ; Middle Aged ; Moxibustion ; methods ; Treatment Outcome

Atherosclerosis ; pathology ; C-Reactive Protein ; metabolism ; Dendritic Cells ; metabolism ; Glycation End Products, Advanced ; metabolism ; Humans ; Inflammation