1.Intralesional Injection of Verapamil Only and Verapamil and Serial Triamcinolone Acetonide in Peyronie's Disease.
Korean Journal of Urology 2000;41(8):999-1003
No abstract available.
Injections, Intralesional*
;
Male
;
Penile Induration*
;
Triamcinolone Acetonide*
;
Triamcinolone*
;
Verapamil*
2.Growth pattern of the newborn infants by gestational age.
Noh Hyun PARK ; Bo Hyun YOON ; Hee Chul SHIN ; Syng Wook KIM
Korean Journal of Obstetrics and Gynecology 1991;34(3):322-330
No abstract available.
Gestational Age*
;
Humans
;
Infant, Newborn*
3.Treatment outcome in patients with triple negative early stage breast cancers compared with other molecular subtypes.
Ja Young KIM ; Sei Kyung CHANG ; Heily PARK ; Bo Mi LEE ; Hyun Soo SHIN
Radiation Oncology Journal 2012;30(3):124-131
PURPOSE: To determine whether triple negative (TN) early stage breast cancers have poorer survival rates compared with other molecular types. MATERIALS AND METHODS: Between August 2000 and July 2006, patients diagnosed with stage I, II early stage breast cancers, in whom all three markers (estrogen receptor, progesterone receptor, and human epidermal growth factor receptor [HER]-2) were available and treated with modified radical mastectomy or breast conserving surgery followed by radiotherapy, were retrospectively reviewed. RESULTS: Of 446 patients, 94 (21.1%) were classified as TN, 57 (12.8%) as HER-2 type, and 295 (66.1%) as luminal. TN was more frequently associated with young patients younger than 35 years old (p = 0.002), higher histologic grade (p < 0.0001), and nuclear (p < 0.0001). The median follow-up period was 78 months (range, 4 to 130 months). There were 9 local relapses (2.0%), 15 nodal (3.4%), 40 distant metastases (9.0%), and 33 deaths (7.4%) for all patients. The rates of 5-year OS, DFS, LFS, and DMFS for all patients were 95.5%, 89.9%, 95.4%, and 91.7%, respectively. There were no significant differences in OS, DFS, LFS, and DMFS between triple negative and other subtypes (p > 0.05). CONCLUSION: We found that patients with TN early stage breast cancers had no difference in survival rates compared with other molecular subtypes. Prospective study in homogeneous treatment group will need for a prognosis of TN early stage breast cancer.
Breast
;
Breast Neoplasms
;
Disease-Free Survival
;
Follow-Up Studies
;
Humans
;
Mastectomy, Modified Radical
;
Mastectomy, Segmental
;
Neoplasm Metastasis
;
Phenobarbital
;
Prognosis
;
Receptor, Epidermal Growth Factor
;
Receptors, Progesterone
;
Recurrence
;
Retrospective Studies
;
Survival Rate
;
Treatment Outcome
5.Postgastrectomy Bezoar Due to Suture Thread.
Jae Keun CHOI ; Min Kyu KIM ; Kyung Bo SHIN ; Jin Hae HYUN
Korean Journal of Gastrointestinal Endoscopy 1981;1(1):41-44
There are various reports referring to the clinical siignificances and removal of postgastrectomy bezoar. In this case, suture thread were thought to he the important factor of the bezoar formation, This bezoar was removed intaetly uaing fiber-optic endoscope in patinet who had postgastrectomy bezoar, by cutting the thread by biopsy forceps.
Bezoars*
;
Biopsy
;
Endoscopes
;
Surgical Instruments
;
Sutures*
6.Pregnancy Outcome According To Elapsing Time After An Immediate Administration Of Antibiotics In A Rabbit Model For The Intrauterine Infection.
Shin Yong MOON ; Bo Hyun YOON ; Hee Chul SYN ; Gyo Hoon PARK
Korean Journal of Obstetrics and Gynecology 1999;42(1):30-40
OBJECTIVE: In a pregnant rabbit model using hysteroscopy-guided inoculation of E. coli, we investigated pregnancy outcome according to elapsing time with immediate antibiotic treatment after E. coli inoculation, and in turn determined which of the maintenance of pregnancy with antibiotic and tocolytic administration or prompt delivery in the management of preterm labor complicated with intrauterine infection offered the improvement of pregnancy outcome. METHODS: Timed-pregnant rabbits underwent hysteroscopy at 20-21 days of gestation(70%). Animals were inoculated with either E. coli(0.2 ml containing 10' cfu/ml) or saline, and administered ampicillin-sulbactam(100 mg/kg/day; Unasyn; Pfizer) in divided doses every 8 hours beginning 30 minutes after microbial inoculation until euthanasia with one of the following; 3 days(n 10), 5 days(n 8), or 7 days(n-8) after hysteroscopy. In the first study, which performed in animals with inoculation of E. coli, pregnancy outcome including fetal survival rate and results of microbial studies and placental pathology were compared among three groups. In second study, which performed in animals with inoculation with saline, pregnancy outcome were compared among three groups for the purpose of elucidating effects of antibiotic administration during inoculation-to-euthanasia interval on pregnancy outcome. RESULTS: Of rabbits inoculated with E. coli and receiving antibiotics immediately, the rate of fetal survival and positive intrauterine cultures in total and live fetuses decreased significantly, and the rate of placental inflammation in total and live fetuses increased significantly with time from intracervical inoculation with E. coli to euthanasia(p<0.05, respectively). Of rabbits inoculated with saline and receiving antibiotics immediately, the rates of fetal survival, positive intrauterine cultures in total and live fetuses, and placental inflammation in total and live fetuses have no difference with time from intracervical inoculation with saline to euthanasia. CONCLUSION: Fetal complications including fetal death could be induced in utero if persistent subclinical intrauterine infection was present in spite of earlier antibiotics administration initiated after inoculation of E, coli. Therefore, when treating with antibiotics in intrauterine infection, it is needed to observe and monitor the presence of persistent intrauterine infection, and if it is persistent, prompt delivery may be better than maintenance of pregnancy with antibiotic and tocolytic administration for the improvement of pregnancy outcome.
Animals
;
Anti-Bacterial Agents*
;
Euthanasia
;
Female
;
Fetal Death
;
Fetus
;
Hysteroscopy
;
Inflammation
;
Obstetric Labor, Premature
;
Pathology
;
Pregnancy
;
Pregnancy Outcome*
;
Pregnancy*
;
Rabbits
;
Survival Rate
7.A case of placenta site trophoblastic tumor(PSTT).
Hyun Tai SHIN ; Seon Kyung LEE ; Chu Yup HUM ; Seung Bo KIM
Korean Journal of Obstetrics and Gynecology 1993;36(12):3976-3982
No abstract available.
Placenta*
;
Trophoblasts*
8.Transient Global Amnesia Due to Hippocampal Infarction.
Joon Hyun SHIN ; Kyung Ho YU ; Bo Ram LEE ; Byung Chul LEE
Journal of the Korean Geriatrics Society 2000;4(4):288-292
Transient global amnesia(TGA) is not a rare event in the elderly, which is characterized by transient inability to form the new memory traces plus retrograde amnesia with benign prognosis. The etiology is unknown, but suggested causes have included transient ischemic attack, migraine, epilepsy, brain tumor, drug intoxication, other toxic/metabolic disturbances, or hysteria. Especially, TGA associated with ischemic stroke is important on the elderly patients and necessary to be differentiated with other causes, for stroke prevention. As far as we know, the case of TGA due to cerebral infarction confirmed by brain imaging study is extremely rare in the literature. We report the case of 67 year-old female patient with typical TGA showing ischemic lesion on the right temporal area on MRI and discussed its significance as one of the cause of TGA.
Aged
;
Amnesia, Retrograde
;
Amnesia, Transient Global*
;
Brain Neoplasms
;
Cerebral Infarction
;
Epilepsy
;
Female
;
Humans
;
Hysteria
;
Infarction*
;
Ischemic Attack, Transient
;
Magnetic Resonance Imaging
;
Memory
;
Migraine Disorders
;
Neuroimaging
;
Prognosis
;
Stroke
9.Traumatic false aneurysm at fracture site: a case report.
Kwon Ick HA ; Sug Ho HAHN ; Minyoung CHUNG ; Bo Kyu YANG ; Kwon Hyun SHIN
The Journal of the Korean Orthopaedic Association 1992;27(1):408-411
No abstract available.
Aneurysm, False*
10.Sleep patterns in Chronic Schizophrenic patients Treated with Clozapine.
Il Seon SHIN ; Seung hyun LEE ; Jin Sang YOON ; Bo yung YOON
Journal of the Korean Society of Biological Psychiatry 1999;6(2):246-253
OBJECTIVES: Daytime drowsiness or sedation and changes in night sleep are commonly seen in patients treated with clozapine. There is, however, very limited informatio on their degree and nature during the course of treatment. The purpose of this study was to understand the sleep patterns in chronic schizophrenic patients with clozapine treatment over a period of 24 weeks. METHOD: The sleep pattern was evaluated using a set of 5-point scale questionnaire, to record subjective impressions of the night sleep induction, maintenance and quality, and daytime drowsiness and fatigue. In addition, unusual experiences associated with night sleep were recorded. The sleep questionnaire was repeatedly administered at baseline and at 1, 2, 4, 8, 12 and 24 weeks of drug treatment. At present, data on 12 patients has been collected. RESULTS: All the components of night sleep were significantly improved in th 1st through the 12 th week after treatment with clozapine. Daytime drowsiness was significantly higher in the 1st to the 2nd week after the treatment and fatigue was also significantly higher in the 1st to the 4th week after the treatment. Eight patients experienced noticeable increases in salivation during night sleep, and of these, one also reported frequent nocturnal urination and even enuresis. However, all these adverse factors did not affect the major sleep patterns. CONCLUSIONS: These finding suggest that the beneficial effects of clozapine on night sleep might last much longer than the undesirable effect of daytime drowsiness and fatigue. In other words, tolerance of the hypnotic action of clozapine might develop late and tolerance of the daytime drowsiness and fatigue might be evident earlier.
Clozapine*
;
Enuresis
;
Fatigue
;
Humans
;
Surveys and Questionnaires
;
Salivation
;
Sleep Stages
;
Urination