Tissues obtained by transurethral prostatectomies were evaluated histologically and correlated with the clinical findings and the transrectal ultrasonographic pictures of 104 patients with benign prostatic hyperplasia (BPH). The patients were divided into 3 groups according to the following histology. predominantly glandular types (30 patients), predominantly stromal types (35 patients) and mixed types which have equal proportions of glandular and stromal hyperplasia (39 patients). The average age was highest in the glandular group. Postoperative obstructive symptom scores were significantly lower in the stromal type as compared to the glandular and the mixed type. The maximal flow rates at three months following the operations were highest in the stromal type. In comparison of the histologic findings with preoperative transrectal echographic pictures, the transverse and the longitudinal diameter of the transitional zone were significantly lower in the stromal type than in the glandular and the mixed type. The weight of transitional zone was significantly smaller in the stromal type than in the glandular and the mixed type. The echogenicity showed hyperechoic and isoechoic pattern in the stromal and the mixed type and hypoechoic and isoechoic pattern in the glandular type. The echographic homogeneity, the frequency of prostatic calculi and cyst formation, and the margination of the transitional zone did not show any significant difference among each group. In conclusion, the histologic types of BPH have correlations with the clinical findings and the transrectal ultrasonographic pictures. Furthermore precise interpretation of the histologic types of BPH by transrectal ultrasonography will be helpful in decision making about the treatment modality and in prediction of the clinical progress after some treatment for the patients with BPH.
Calculi ; Decision Making ; Humans ; Hyperplasia ; Prostatic Hyperplasia* ; Transurethral Resection of Prostate ; Ultrasonography

Retroperitoneal lipoma probably constitute the group of the most massive solid abdominal tumors; their etiology is unknown; their symptoms insidious; and recurrence and sarcomatous change frequent. The clinical diagnosis was made by clinical symptoms, physical findings and radiologic evaluation such as intravenous urography, ultrasonography, computed tomography, angiography and so on. Abdominal CF scan provided clinically the most useful information regarding the state of tumors and also their effect on adjacent structures and shows homogenous appearing fat tissue with a low attenuation coefficient identical to that found in the subcutaneous fat. We present a case of treatment for a huge retroperitoneal lipoma in a 46-year-old man.
Angiography ; Diagnosis ; Humans ; Lipoma* ; Middle Aged ; Recurrence ; Subcutaneous Fat ; Ultrasonography ; Urography

Renal leiomyoma, a rare benign tumor, is a challenging diagnostic and therapeutic condition. The preoperative diagnosis of renal leiomyoma is very difficult, and the only definite method to distinguish between a leiomyoma and other renal tumor is postoperative microscopic evaluation. We report a case of leiomyoma of the kidney which was managed by radical nephrectomy under the impression of malignant renal mass which was incidentally found by ultrasonographic examination for health check in a 43-year-old woman.
Adult ; Diagnosis ; Female ; Humans ; Kidney* ; Leiomyoma* ; Nephrectomy

We report our experience with the diagnostic, clinical and biochemical findings, complications and maternal-perinatal outcome in a case of acute fatty liver of pregnancy. A 31-year-old multipara presented herself at 35 weeks' gestation with general malaise, gastroesophageal reflux, jaundice, hepatorenal dysfunction and disseminated intravascular coagulation. An abdominal ultrasound revealed a mild fatty liver. A tentative diagnosis of acute fatty liver of pregnancy was made, and immediately a healthy male infant weighing 2330 gm was delivered by emergency cesarean section. On 1, 2 and 6 days after delivery, oliguria, acute respiratory distress syndrome and pancreatitis developed, respectively. Abnormal levels of AST/ALT, creatinine, fibrinogen, PT/PTT and platelet recovered to normal ranges 7-10 days after delivery. Serum amylase and lipase became normal 24 days after delivery with conservative treatment. Ventilator care for acute respiratory distress syndrome continued up to 49 days after delivery, when total bilirubin, ammonia, alkaline phosphatase, r-GT, and AST/ALT began to normalize. The discharge was recommended on the 88th postpartum day. Our result suggests that acute fatty liver of pregnancy can be diagnosed on the basis of clinical and laboratory findings. Prompt delivery, intensive supportive care and awareness of its complications can markedly improve maternal and perinatal outcome.
Adult ; Alkaline Phosphatase ; Ammonia ; Amylases ; Bilirubin ; Blood Platelets ; Cesarean Section ; Child* ; Creatinine ; Diagnosis ; Disseminated Intravascular Coagulation ; Emergencies ; Fatty Liver* ; Female ; Fibrinogen ; Gastroesophageal Reflux ; Humans ; Infant ; Jaundice ; Lipase ; Male ; Mothers* ; Oliguria ; Pancreatitis ; Postpartum Period ; Pregnancy* ; Reference Values ; Respiratory Distress Syndrome, Adult* ; Ultrasonography ; Ventilators, Mechanical

The present study evaluated the effect of various dosages of soybean isoflavone extract on body weight changes, glucose tolerance and liver function in streptozotocin-induced diabetic rats. One group of normal rats (normal control) was fed an AIN-76-based experimental diet and four groups of diabetic rats were fed the same diet supplemented with four different levels of soybean isoflavone extract for seven weeks. The daily dosages of pure isoflavone for four diabetic groups were set to be 0 mg (diabetic control), 0.5 mg (ISO-I), 3.0 mg (ISO-II) and 30.0 mg (ISO-III) per kilogram of body weight, respectively. The daily consumption of isoflavone at the level of 3.0mg per kilogram of body weight resulted in the suppression of body weight loss and increased the survival rate of diabetic animals one and half times compared to that of the diabetic control group. Blood glucose levels in a fasting state and after the oral administration of glucose were significantly lower in the ISO-II group during the oral glucose tolerance test. The ISO-II group showed a tendency to elongate the gastrointestinal transit time. The activity of serum aminotransferases, indicator of liver function, was not negatively affected by any intake level of isoflavone. The present study demonstrated that the soybean isoflavone extract may be beneficial to diabetic animals by improving their glucose tolerance and suppressing weight loss without incurring hepatotoxicity at the daily dosage of 3.0 mg per kg of body weight.
Administration, Oral ; Animals ; Blood Glucose ; Body Weight ; Body Weight Changes ; Diet ; Fasting ; Gastrointestinal Transit ; Glucose Tolerance Test ; Glucose* ; Liver ; Rats* ; Soybeans* ; Streptozocin ; Survival Rate* ; Transaminases ; Weight Loss

PURPOSE: Patients with planovalgus show various abnormal gaits and these are affected by the different length and velocity of the muscles around knee and ankle. The purpose of study is to compare the length and velocity of gastrocnemius in cerebral palsy with planovalgus by ankle plantarflexion-knee extension couple. MATERIALS AND METHODS: 22 patients with spastic diplegia who have planovalgus were included. The mean age was 12 years (5 years~18 years). Group I consisted of 7 patients with knee flexion more than 30 degrees and Group II consisted of 15 patients with knee flexion less than 15 degrees during mid-stance phase. Normal groups were consisted of 15 normal children. RESULTS: In patients with planovalgus, ankle dorsiflexion during stance was decreased but ankle plantarflexion was not different compared to normal. There is no difference in the percent length of gastrocnemius compared to normal, but the velocity was decreased. The percent length of gastrocnemius was decreased in group I, but there were no difference in the velocity. CONCLUSION: The decreased velocity of gastrocnemius is the cause of disability of ankle plantarflexion-knee extension couple and the variable length of gastrocnemius is the cause of variability of abnormal gait.
Animals ; Ankle ; Cerebral Palsy ; Child ; Foot ; Foot Deformities ; Gait ; Humans ; Knee ; Muscle, Skeletal ; Muscles

We present a patient with moyamoya disease and a ruptured superior cerebellar artery aneurysm that was managed by endovascular embolization. A 53-year-old man with sudden onset severe headache and altered mental status was referred to our hospital. Computed tomography revealed a subarachnoid hemorrhage. Cerebral angiography showed evidence of moyamoya disease and a 7 mm saccular aneurysm at the origin of the right superior cerebellar artery. Endovascular coil embolization was performed successfully without posterior cerebral artery and superior cerebellar artery obliteration. Endovascular treatment with microcoils appear particularly safe for moyamoya patients with cerebral saccular aneurysms.
Aneurysm ; Arteries ; Cerebral Angiography ; Headache ; Humans ; Middle Aged ; Moyamoya Disease ; Polyenes ; Posterior Cerebral Artery ; Subarachnoid Hemorrhage

PURPOSE: This study was performed to investigate the effects of intravesical instillation of cyclooxygenase-2 (COX-2) inhibitors on the cyclophosphamide-induced overactive bladder. MATERIALS AND METHODS: The 40 Sprague-Dawley rats were divided into 3 groups; the control group, the overactive group, and the COX-2 inhibitor treated group. Cystometrograms (CMG) were performed and the contraction interval, inter-contraction interval, contraction time and contraction pressure were measured. After CMG, the bladders of each group were dissected out, and weighed. RESULTS: On CMG, the contraction interval and inter-contraction interval for the overactive group were significantly decreased compared with the control group. After treatment with COX-2 inhibitor, the contraction interval and inter-contraction interval were significantly increased compared with the overactive group (p<0.05). The contraction time in the overactive group was significantly increased compared with the control group, and it was also decreased in the COX-2 inhibitor treated group compared with the overactive group (p<0.05). The contraction pressure in the overactive group and the COX-2 inhibitor treated group were significantly increased compared with the control group. There were no significant differences between the overactive and COX-2 inhibitor treated groups. The bladder weights of the overactive and COX-2 inhibitor treated groups were significantly increased compared with the control group (p<0.05). CONCLUSIONS: Intravesical instillation of COX-2 inhibitor can suppress cyclophosphamide-induced detrusor overactivity. Therefore, intravesical instillation of COX-2 inhibitor may be considered as a possible treatment for the overactive bladder.
Administration, Intravesical* ; Cyclooxygenase 2 Inhibitors ; Cyclooxygenase 2* ; Cyclophosphamide ; Rats, Sprague-Dawley ; Urinary Bladder ; Urinary Bladder, Overactive* ; Weights and Measures

PURPOSE: This study was performed to investigate the effects of intravesical instillation of cyclooxygenase-2 (COX-2) inhibitors on the cyclophosphamide-induced overactive bladder. MATERIALS AND METHODS: The 40 Sprague-Dawley rats were divided into 3 groups; the control group, the overactive group, and the COX-2 inhibitor treated group. Cystometrograms (CMG) were performed and the contraction interval, inter-contraction interval, contraction time and contraction pressure were measured. After CMG, the bladders of each group were dissected out, and weighed. RESULTS: On CMG, the contraction interval and inter-contraction interval for the overactive group were significantly decreased compared with the control group. After treatment with COX-2 inhibitor, the contraction interval and inter-contraction interval were significantly increased compared with the overactive group (p<0.05). The contraction time in the overactive group was significantly increased compared with the control group, and it was also decreased in the COX-2 inhibitor treated group compared with the overactive group (p<0.05). The contraction pressure in the overactive group and the COX-2 inhibitor treated group were significantly increased compared with the control group. There were no significant differences between the overactive and COX-2 inhibitor treated groups. The bladder weights of the overactive and COX-2 inhibitor treated groups were significantly increased compared with the control group (p<0.05). CONCLUSIONS: Intravesical instillation of COX-2 inhibitor can suppress cyclophosphamide-induced detrusor overactivity. Therefore, intravesical instillation of COX-2 inhibitor may be considered as a possible treatment for the overactive bladder.
Administration, Intravesical* ; Cyclooxygenase 2 Inhibitors ; Cyclooxygenase 2* ; Cyclophosphamide ; Rats, Sprague-Dawley ; Urinary Bladder ; Urinary Bladder, Overactive* ; Weights and Measures

BACKGROUND: Nickel-sensitive patients may suffer from persistent dermatitis even if they avoid cutaneous contact with nickel-plated items. Therefore, an endogenous cause of nickel-induced dermatitis has been suggested. In Western countries, many studies suggested that reduction of dietary intake of nickel might benefit nickel-sensitive patients. OBJECT: We measured the nickel content of Korean foods, since a nickel-restricted diet is essential for nickel-sensitive patients. METHOD: We ground the food, then nitric acid, sulphuric acid, and fluoric acid were added to the ground foods to dissolve organic matter. We then measured nickel content in these samples using Inductive Coupled Plasma-Mass Spectrometry. RESULTS: A green tea bag contained 235.57mg Ni/kg, a black tea bag 62.79mg Ni/kg, chocolate 27.87mg Ni/kg, crisps 12.70mg Ni/kg, wheat flour 12.15mg Ni/kg, Welsh onion 0.026mg Ni/kg, garlic 0.016mg Ni/kg, milk 0.004 mg Ni/kg, egg 0.002mg Ni/kg, and salt 0.0mg Ni/kg. CONCLUSION: High nickel concentrations were found in green tea bag, chocolate, crisps, wheat flour, coffee bean, peanuts, and kimchi etc. On the other hand, rice, barley and spice had low content of nickel. Formulation of nickel-restricted diet using these results is expected to be helpful in the treatment of nickel-sensitive patients.
Arachis ; Cacao ; Coffee ; Dermatitis ; Diet ; Flour ; Garlic ; Hand ; Hordeum ; Humans ; Milk ; Nickel* ; Nitric Acid ; Onions ; Ovum ; Spectrum Analysis ; Spices ; Tea ; Triticum