1.Production and Characterization of Human CD27lg, CD40fg and CD95lg Fusion Proteins in Chinese Hamster Ovary Cell.
Bo Hyun CHO ; Yong Hoon CHUNG ; Yang Ja CHO
Korean Journal of Immunology 2000;22(4):253-264
No abstract available.
Animals
;
Asian Continental Ancestry Group*
;
Cricetinae
;
Cricetulus*
;
Female
;
Humans*
;
Ovary*
2.A 5 - Year Clinical Study on Herpes Zoster: 1990 - 1994.
Si Young KIM ; Bo Hyun CHO ; Joong Hwan KIM
Korean Journal of Dermatology 1997;35(2):266-272
BACKGROUND: Herpes zoster is an important and troublesome disease. OBJECTIVE: The purpose of this study was the elucidation of the epidemiological and clinical characteristics of herpes zoster through patient assessrnent. METHODS: During a 5- Year period, January 1990 to December 1994, 215 patients with herpes zoster were assessed with regard to annual and monthly frequency in occurrence, age and gender incidence. Associated conditions, dermatomic distributions, the relationship of onset of pain and skin lesions, Multi-CMI test and complications were also evaluated. RESULTS: 1. The annual freguency of herpes zoster ranged from 0.88% to 1.78% (mean 1.23%) during the 5-year period. The highest number of herpes zoster patients was observed in winter (p<0.001) especially in January. 2. Herpes zoster was found to most frequently afflict persons aged 50-59 (27.9%). 71% of the patients were over 40 years of age. 3. In 76 patients (41.8%), neuralgia occurred several days (4 days mean) before the development of skin lesions. In 92 patients (50.5%), pain and skin lesions developed simultaneously while skin lesion development occurred before the onset of pain in 14 patients (7.7%). 4. Among the patients, 42.8% had associated conditions such as diabetes mellitus, hypertension, pulmonary tuberculosis, liver diseases, peptic ulcer, hypothyroidism, pharyngitis, fracture, etc. 5. The dermatomic invclvement of herpes zoster patients having one dermatome was most frequent in thoracic dermatome ca. es (52.6%). Others included cervical (16.7%), trigeminal (11.6%), sacral (6. 0%), lumbar (4.2%), facial (0.5%). Cases having two different dermatomes constituted 8.4%. 6. The most common complication of herpes zoster was postherpetic neuralgia although instance of ophthalmologic compiications, secondary bacterial infection, scar formation, Ramsay-Hunt syndrome, keloid formation, and urinary difficulty were also documented. 7. Multi-CMI (Cell-mediated immunity) tests were done on 88 herpes zoster patients. Thirteen of them (14.8%) were found to have comparatively depressed scores. Ten of the 79 single dermatome involvement patients (12.7%) and three of the 9 two dermatome involvement patients (33.3%) exhibited similar scores. CONCLUSION: These results are in accordance with those of previous reports with the exception of the higher incidence ot two different dermatome involvements and seasonal variation.
Bacterial Infections
;
Cicatrix
;
Diabetes Mellitus
;
Herpes Zoster*
;
Humans
;
Hypertension, Pulmonary
;
Hypothyroidism
;
Incidence
;
Keloid
;
Liver Diseases
;
Neuralgia
;
Neuralgia, Postherpetic
;
Peptic Ulcer
;
Pharyngitis
;
Seasons
;
Skin
;
Tuberculosis
3.Clinical study of hydrofluoric acid burn.
Bo Hyun CHO ; Kea Jeung KIM ; Hyung Jai KANG
Korean Journal of Dermatology 1993;31(5):672-680
BACKGROUND: Hydrofluoric acid burns are occuring with ever-increiisir g frequency due to the wide use of this acid in industrial fields, such as electronics and semiconductor i idustries. OBJECTIVE: The purpose of thie study was to evaluate the clinical charateristics of hydrofluoric acid burn. This study will give basic information of hydrofluoric acid burn to the dermatologists who are not familiar with hydrofluoric acid. METHOD: Twenty-two patient who were diagnosed as having hydroiluiiric acid burns at koryo General Hospital(1986-1993) were irraluated clinical)y. Forteen were malc ar d eight were female, most of them were in their third decade. RESULTS: The results are sumrnurised as follows 1. Latent periods were variabie from 30 min. to 3 days. Most patients recognized their chemical burn several hours after exposure. 2. Foot & sole (9 cases) and fingers (7 cases) were most frequently in olved. In 7 cases, nails were also involved. 3. Pain was the most. commori iuobjective symptom. 4. Skin lesions showed erytherna, erythematous swelling, erosion, bulla., necrosis, pigmentation and crust, formation, progressii ely. 5. Treatment Wet dressing with Hyami-solution and topical application of ai tibiotics or steroidointment were sufficient in mild case. In severe cases, intralesional injection of calcium glucoante was perfirmed. Debridement was also performed after the progn ssion of tissue damage stopped. Nails were extracted in cases involving nails. CONCLUSION: Hydrofluoric acid burn is characterized clinically by severc progessive tissue destruction and excruciating pain. Dermatologists need to be aware of the clinical features of hydroclucric acid burn and its proper treatment.
Bandages
;
Burns*
;
Burns, Chemical
;
Calcium
;
Debridement
;
Female
;
Fingers
;
Foot
;
Humans
;
Hydrofluoric Acid*
;
Injections, Intralesional
;
Necrosis
;
Pigmentation
;
Semiconductors
;
Skin
4.Graves' disease complicating pregnancy.
Sung Soo KIM ; Bo Hyun YOON ; Bo Youn CHO ; Hee Chul SYN ; Syng Wook KIM
Korean Journal of Perinatology 1991;2(1):105-113
No abstract available.
Graves Disease*
;
Pregnancy*
5.A Case of Sacrococcygeal teratoma complicated by hydronephrosis and hydroureter.
Doo Sung MOON ; Kyung Sook CHO ; Jong Dae CHO ; In Ki SUNG ; Bo Hyun HAN
Journal of the Korean Pediatric Society 1988;31(1):134-140
No abstract available.
Hydronephrosis*
;
Teratoma*
6.A Study on the Characteristics of Intentional Self-Poisoning Patients :Comparison between Non-Prescription and Prescription Drugs
Eulah CHO ; Ji Hyun CHO ; Kyeng Hyeng JHO ; Hyun-Bo SIM
Korean Journal of Psychosomatic Medicine 2020;28(2):116-125
Objectives:
:Self-poisoning is the leading cause of visits to the emergency departments after a suicide attempts. This study is aimed to compare the patient characteristics according to the category of drugs ingested by the patients who attempted suicide.
Methods:
:All medical charts were retrospectively reviewed from patients who visited the emergency center, at Seoul Medical Center, due to intentional self-poisoning from April of 2011 to July of 2019. We investigated the information regarding the subtype and quantity of the intoxication drug, how it was obtained, suicidal history, and psychiatric history, as well as, sociodemographic information. Variables were compared between prescription drug (PD) and non-prescription drug (NPD) poisoning groups.
Results:
:The mean age of the NPD poisoning group was significantly lower than that of the PD poisoning group. The patient ratio of those enrolled in national health insurance and living with spouses were significantly higher in the NPD poisoning group. Compared to the NPD poisoning group, the PD poisoning group had a higher incidence of mental illnesses, underlying diseases and ratio of involuntary visit to the emergency department.Among the prescription drugs, the benzodiazepine poisoning group had a higher rate of self-prescription than the non-poisoning group, while the zolpidem poisoning group had a higher rate of the using someone else’s prescription than other drugs. Each single drug poisoning group (benzodiazepine, zolpidem, and antidepressant singleagent) had a higher rate of no mental illness than each of the mixed-poisoning group.
Conclusions
:Guidelines for regulating non-prescription drugs are needed as a matter of suicide prevention. Also, this study suggests that clinicians need to be careful when issuing prescriptions and should suicidal risk according to patients’ characteristics, duration of follow-up and type of drug packaging.
7.A Study on the Characteristics of Intentional Self-Poisoning Patients :Comparison between Non-Prescription and Prescription Drugs
Eulah CHO ; Ji Hyun CHO ; Kyeng Hyeng JHO ; Hyun-Bo SIM
Korean Journal of Psychosomatic Medicine 2020;28(2):116-125
Objectives:
:Self-poisoning is the leading cause of visits to the emergency departments after a suicide attempts. This study is aimed to compare the patient characteristics according to the category of drugs ingested by the patients who attempted suicide.
Methods:
:All medical charts were retrospectively reviewed from patients who visited the emergency center, at Seoul Medical Center, due to intentional self-poisoning from April of 2011 to July of 2019. We investigated the information regarding the subtype and quantity of the intoxication drug, how it was obtained, suicidal history, and psychiatric history, as well as, sociodemographic information. Variables were compared between prescription drug (PD) and non-prescription drug (NPD) poisoning groups.
Results:
:The mean age of the NPD poisoning group was significantly lower than that of the PD poisoning group. The patient ratio of those enrolled in national health insurance and living with spouses were significantly higher in the NPD poisoning group. Compared to the NPD poisoning group, the PD poisoning group had a higher incidence of mental illnesses, underlying diseases and ratio of involuntary visit to the emergency department.Among the prescription drugs, the benzodiazepine poisoning group had a higher rate of self-prescription than the non-poisoning group, while the zolpidem poisoning group had a higher rate of the using someone else’s prescription than other drugs. Each single drug poisoning group (benzodiazepine, zolpidem, and antidepressant singleagent) had a higher rate of no mental illness than each of the mixed-poisoning group.
Conclusions
:Guidelines for regulating non-prescription drugs are needed as a matter of suicide prevention. Also, this study suggests that clinicians need to be careful when issuing prescriptions and should suicidal risk according to patients’ characteristics, duration of follow-up and type of drug packaging.
8.A study of factors influencing the length of stay in the emergency department of patients who were admitted after a self-poisoning suicidal attempt
Ganggi LEE ; Eulah CHO ; Ji Hyun CHO ; Hyun-Bo SIM ; Jinhyung PARK ; Chang Hae PYO ; Hyun Kyung PARK ; Keunhong PARK
Journal of the Korean Society of Emergency Medicine 2021;32(6):647-656
Objective:
A suicide attempt by self-poisoning is a common cause of admissions to the emergency department (ED). Management of such intentiona poisoning often requires complicated medical procedures, resulting in a longer length of stay (LOS) as compared to other cases that require treatment in the ED. This study aimed to determine the factors affecting a longer LOS in self-poisoning patients.
Methods:
This was a retrospective study wherein all the medical charts of patients who visited the ED of one hospital, from August 2016 to July 2019, because of intentional self-poisoning, were reviewed.
Results:
Most of the patients visited the ED involuntarily and there were almost twice as many female patients as males. Almost half of the patients were referred to the psychiatry department. A comparison of various factors within the LOS groups revealed significant differences in mental status, guardian co-visitation, patient gender, psychiatric referral, and poisoning substance. Moreover, the LOS had a stronger association with the pre-consultation period than the consultation to decision-making period.
Conclusion
To reduce the LOS, it seems important to make a rapid decision on whether to observe the patient in the ED and wait until the workup is completed or to admit and then evaluate the patient in the ward. If the clinicians cannot obtain enough information to evaluate the patient for appropriate management, short-term admission may be an option to reduce the LOS and to provide a stable evaluation.
9.Two Cases of Congenital Chylothorax Diagnosed by Prenatal Ultrasonography.
Kyung Hyun CHUNG ; Wan CHO ; Man Yong HAN ; Bo Kyung KIM ; Kyu Hyung LEE
Korean Journal of Perinatology 1999;10(4):512-517
Congenital chylothorax is a rare disorder and can be diagnosed by prenatal ultrasonography recently. Most cases of congenital chylothorax were characterized by different clinical courses of respiratory distress. We describe two female cases with congenital chylothorax observed by ultra- sonography prenatally. In the first case, left-sided pleural effusion was noted by prenatal ultrasonography taken at 34 weeks of gestation, and then pleural fluid was extracted by intrauterine thoracentesis under sonography guidance. After birth, this patient was managed by TPN(total parentral nutrition) and intermittent thoracentesis without surgical treatment. But, pleural fluid was accumulated recurrently and respiratory distress was aggravated. At 15th hospital day, shock state was developed and patient died. In the second case, bilateral pleural effusion and ascites were noted by prenatal ultrasonography, and then patient was delivered immediately without intrauterine thoracentesis. After birth, the second case received conservative therapy including mechanical ventilation, TPN, intermittent thoracentesis and paracentesis. The patient was discharged with complete regression of chylothorax. We report the two cases with brief review of related literatures.
Ascites
;
Chylothorax*
;
Female
;
Humans
;
Paracentesis
;
Parturition
;
Pleural Effusion
;
Pregnancy
;
Respiration, Artificial
;
Shock
;
Ultrasonography, Prenatal*
10.Urethrotomy Under Endoscopic Direct Vision in the Management of Urethral Stricture.
Korean Journal of Urology 1985;26(3):231-236
28 times of Urethrotomy under endoscopic direct vision was made on 26 patients with urethral stricture. The results were as follows: l. Urethrotomy under endoscopic direct vision was highly useful for the primary management of any urethral stricture without associating with portion and length of stricture. 2. It could be easily repeated when the stricture recurred. 3. It was very safe, with few complications, 1 case of false passage and 2 cases of acute epididymitis and 2 cases of urinary incontinence.
Constriction, Pathologic
;
Epididymitis
;
Humans
;
Male
;
Urethral Stricture*
;
Urinary Incontinence