1.The Fusion Rate and Clinical Effect of PLIF with Laminected Lamina and Spinous Process.
Joo Tae PARK ; Young Shik SHIN ; Jeong Ho YANG ; Bo Gun SEO
Journal of Korean Society of Spine Surgery 1998;5(1):79-85
STUDY DESIGN: This is a retrospective study analyzing 73 patients treated by decompression, pedicular screw instrumentation and posterior lumbar interbody fusion (PLIF) for lumbosacral spondylolithesis and symptomatic spinal stenosis. we used laminected laminar and spinous process instead of iliac bone. OBJECTIVES: This is to evaluate fusion rate and clinical results of PLIF with laminected laminar and spinous process. MATERIALS AND METHODS: PLIF in 73 patients with lumbosacral disorders who carried out at Pohang St. Mary's Hospital from March 1994 to January 1996. Fusion rate was evaluated by simple X-ray and dynamic view. Clinical effect was evaluated by Kirkaldy-Willis criteria. RESULTS: The solid fusion was achieved at 67 cases(91.8%) and the average period of fusion was 6.4 months. Complications were 2 cases of superficial skin infection and 3 cases of root irritation. The functional results by Kirkaldy-Willis were as follows ; excellent 40 cases, good 23 cases, fair 9 cases and poor 1 case. CONCLUSIONS: This PLIF procedure combined with transpedicular instrumentation showed sufficient fusion rate and excellent clinical results and improvement in vertebral alignment.
Decompression
;
Gyeongsangbuk-do
;
Humans
;
Retrospective Studies
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Skin
;
Spinal Stenosis
2.Mycoplasma pneumoniae associated stroke in a 3-year-old girl.
Gun Ha KIM ; Won Hee SEO ; Bo Kyung JE ; So Hee EUN
Korean Journal of Pediatrics 2013;56(9):411-415
Infectious diseases precede a significant proportion of acute ischemic strokes in children. Here, we report a case of acute ischemic stroke in a 3-year-old girl with a Mycoplasma pneumonia-associated respiratory tract infection. She developed an acquired prothrombotic state of protein S deficiency and had increased fibrinogen and fibrinogen degradation product levels and increased titer of antinuclear antibodies. However, these conditions were completely alleviated at the 1-month follow-up examination. Infection with M. pneumoniae may cause a transient prothrombotic state that can potentially cause a thrombus.
Antibodies, Antinuclear
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Child
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Communicable Diseases
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Fibrinogen
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Follow-Up Studies
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Humans
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Mycoplasma
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Mycoplasma pneumoniae
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Pneumonia
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Pneumonia, Mycoplasma
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Preschool Child
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Protein S Deficiency
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Respiratory Tract Infections
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Stroke
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Thrombosis
3.Immature Teratoma and Subsequent Acute Promyelocytic Leukemia in a Pediatric Patient With XYY Syndrome.
Ju Heon PARK ; Hyun Woo CHOI ; Bo Young SEO ; Min Goo KANG ; Soo Hyun KIM ; Hee Jo BAEK ; Hoon KOOK ; Myung Geun SHIN
Annals of Laboratory Medicine 2015;35(5):544-547
No abstract available.
Humans
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Leukemia, Promyelocytic, Acute*
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Teratoma*
4.Educating restaurant owners and cooks to lower their own sodium intake is a potential strategy for reducing the sodium contents of restaurant foods: a small-scale pilot study in South Korea.
Sohyun PARK ; Heeseung LEE ; Dong il SEO ; Kwang Hwan OH ; Taik Gun HWANG ; Bo Youl CHOI
Nutrition Research and Practice 2016;10(6):635-640
BACKGROUND/OBJECTIVES: This study was conducted to evaluate the feasibility of a sodium reduction program at local restaurants through nutrition education and examination of the health of restaurant owners and cooks. SUBJECTS/METHODS: The study was a single-arm pilot intervention using a pre-post design in one business district with densely populated restaurants in Seoul, South Korea. The intervention focused on improving nutrition behaviors and psychosocial factors through education, health examination, and counseling of restaurant personnel. Forty-eight restaurant owners and cooks completed the baseline survey and participated in the intervention. Forty participants completed the post-intervention survey. RESULTS: The overweight and obesity prevalences were 25.6% and 39.5%, respectively, and 74.4% of participants had elevated blood pressure. After health examination, counseling, and nutrition education, several nutrition behaviors related to sodium intake showed improvement. In addition, those who consumed less salt in their baseline diet (measured with urine dipsticks) were more likely to agree that providing healthy foods to their customers is necessary. This study demonstrated the potential to reduce the sodium contents of restaurant foods by improving restaurant owners' and cooks' psychological factors and their own health behaviors. CONCLUSIONS: This small pilot study demonstrated that working with restaurant owners and cooks to improve their own health and sodium intake may have an effect on participation in restaurant-based sodium reduction initiatives. Future intervention studies with a larger sample size and comparison group can focus on improving the health and perceptions of restaurant personnel in order to increase the feasibility and efficacy of restaurant-based sodium reduction programs and policies.
Blood Pressure
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Commerce
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Counseling
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Diet
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Education
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Health Behavior
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Health Education
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Korea*
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Nutrition Policy
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Obesity
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Overweight
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Pilot Projects*
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Prevalence
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Psychology
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Restaurants*
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Sample Size
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Seoul
;
Sodium*
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Surveys and Questionnaires
5.Arachnoid Membrane Suturing for Prevention of Subdural Fluid Collection in Extracranial-intracranial Bypass Surgery.
Gun Woo KIM ; Sung Pil JOO ; Tae Sun KIM ; Hyung Sik MOON ; Jae Won JANG ; Bo Ra SEO ; Jung Kil LEE ; Jae Hyoo KIM ; Soo Han KIM
Journal of Cerebrovascular and Endovascular Neurosurgery 2014;16(2):71-77
OBJECTIVE: Water-tight closure of the dura in extracranial-intracranial (EC-IC) bypass is impossible because the superficial temporal artery (STA) must run through the dural defect. Consequently, subdural hygroma and subcutaneous cerebrospinal fluid (CSF) collection frequently occur postoperatively. To reduce these complications, we prospectively performed suturing of the arachnoid membrane after STA-middle cerebral artery (STA-MCA) and evaluated the clinical usefulness. MATERIALS AND METHODS: Between Mar. 2005 and Oct. 2010, extracranial-intracranial arterial bypass (EIAB) with/without encephalo-myo-synangiosis was performed in 88 cases (male : female = 53 : 35). As a control group, 51 patients (57 sides) underwent conventional bypass surgery without closure of the arachnoid membrane. Postoperative computed tomography (CT) scan was performed twice in three days and seven days later, respectively, for evaluation of the presence of subdural fluid collection and other mass lesions. RESULTS: The surgical result was excellent, with no newly developing ischemic event until recent follow-up. The additional time needed for arachnoid suture was five to ten minutes, when three to eight sutures were required. Post-operative subdural fluid collection was not seen on follow-up computed tomography scans in all patients. CONCLUSION: Arachnoid suturing is simple, safe, and effective for prevention of subdural fluid collection in EC-IC bypass surgery, especially the vulnerable ischemic hemisphere.
Arachnoid*
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Cerebral Arteries
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Cerebral Revascularization
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Cerebrospinal Fluid
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Female
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Follow-Up Studies
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Humans
;
Membranes*
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Prospective Studies
;
Subdural Effusion
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Sutures
;
Temporal Arteries
6.A Fatal Spontaneous Gas Gangrene due to Clostridium perfringens during Neutropenia of Allogeneic Stem Cell Transplantation: Case Report and Literature Review.
Hae Lim LEE ; Sung Yeon CHO ; Dong Gun LEE ; Yumi KO ; Ji In HYUN ; Bo Kyoung KIM ; Jae Hyun SEO ; Jung Woo LEE ; Seok LEE
Infection and Chemotherapy 2014;46(3):199-203
Most cases of gas gangrene caused by Clostridium species begin with trauma-related injuries but in rare cases, spontaneous gas gangrene (SGG) can occur when patients have conditions such as advanced malignancy, diabetes, or immunosuppression. Clostridium perfringens, a rare cause of SGG, exists as normal flora of skin and intestines of human. Adequate antibiotics with surgical debridement of infected tissue is the only curative therapeutic management. Mortality rate among adults is reported range of 67-100% and majority of deaths are occurred within 24 hours of onset. We experienced a case of SGG on the trunk, buttock and thigh in a neutropenic patient with acute lymphoblastic leukemia. His clinical course was rapid and fatal during pre-engraftment neutropenic period of allogeneic stem cell transplantation.
Adult
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Anti-Bacterial Agents
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Buttocks
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Clostridium
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Clostridium perfringens*
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Debridement
;
Gas Gangrene*
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Humans
;
Immunosuppression
;
Intestines
;
Mortality
;
Neutropenia*
;
Precursor Cell Lymphoblastic Leukemia-Lymphoma
;
Skin
;
Stem Cell Transplantation*
;
Thigh
7.Effects of Amniotic Membrane Extract on the Hyperplastic Response of the Middle Ear Mucosa in a Bacterially-Induced Otitis Media Rat Model: A Preliminary Study
Joo Hyun PARK ; Hee-Bok KIM ; Seo Hyun KO ; Bo Hae KIM ; Yun-Sung LIM ; Seok-Won PARK ; Jae-Jun SONG ; Chang Gun CHO
Clinical and Experimental Otorhinolaryngology 2020;13(4):381-388
Objectives:
. Human amniotic membrane extract (AME) is known to contain numerous bioactive factors and anti-inflammatory substances. However, the anti-inflammatory effects of AME on the middle ear (ME) mucosa are unclear. This study assessed the effects of AME on the growth of the ME mucosa in response to bacterially-induced otitis media (OM).
Methods:
. OM was induced by inoculating nontypeable Haemophilus influenzae (NTHi) into the ME cavity of rats. ME mucosal explants were cultured in AME concentrations of 0, 5, 10, or 50 μg/mL. The area of explant outgrowth was measured in culture and analyzed at 1, 3, 5, and 7 days after explantation. The expression of Ki-67, mucin 5AC (MUC5AC), tumor necrosis factor-α (TNF-α), and interleukin-10 (IL-10) in the explants was also evaluated using quantitative polymerase chain reaction (PCR) and immunocytochemistry (ICC).
Results:
. The NTHi-induced ME mucosa growth increased gradually over the 7-day culture period in all explants at different AME concentrations. There was a trend for mucosal growth inhibition at higher concentrations of AME, although the growth was not significantly different among the groups until day 5. The ME mucosal explants treated with the 50 μg/mL concentration of AME showed significantly suppressed growth on postexplantation day 7 compared with other explants on the same day. PCR and ICC staining revealed that the expression of Ki-67, MUC5AC, TNF-α, and IL-10 further decreased in the explants with higher concentrations of AME than in those with lower concentrations of AME.
Conclusion
. Our results showed that higher concentrations of AME reduced the mucosal proliferative response in bacterial OM in rats. These findings provide evidence that AME has an influence on the inflammatory and proliferative responses to NTHi infection in ME mucosa.
8.The Clinical Significance of Ann Arbor and Musshoff's Staging System in Primary Gastrointestinal Non-Hodgkin's Lymphoma-A Retrospective Analysis.
Kwang Woon SEO ; Dong Hwan KIM ; Woo Jin SUNG ; Sung Won PARK ; Jong Gwang KIM ; Jin Tae JUNG ; Tae In PARK ; Se Hwan KIM ; Dong Gun SHIN ; Sang Kyun SOHN ; Kyu Bo LEE
Korean Journal of Hematology 2001;36(4):275-285
BACKGROUND: Primary Gastrointestinal Non- Hodgkin's Lymphoma (GIL) represents 4 to 20 % of all Non-Hodgkin's Lymphoma(NHL) and gastrointestinal tract(GIT) is the most frequently involved extranodal site in NHL. It is known that the prognosis of GIL is better than that of other NHLs because of it's unique biologic behavior and anatomical location. We reviewed clinical aspects of GIL and analyzed survival data based on Ann-Arbor and Musshoff's staging system. METHODS: Sixty six cases were analyzed by age, sex, clinical manifestation, location, histology, clinical course, and two staging systems (Ann Arbor and Musshoff's modified staging). Histologies were reviewed according to REAL classification. RESULTS: The median age was 51.5 years. The most frequent gross finding was ulcerofungating lesion in upper GIL and mass lesion in lower GIL. Treatment results were as following : 76.9% of response rate, 59.5% of 5-year overall survival rate, and 54.8% of 5-year disease free survival rate. There was a significant difference of overall survival or disease free survival rate between group below stage IIE1 and above IIE2 according to Musshoff's staging system. There were no significant differences in survival between stage I and II, and between stage III and IV based on Ann Arbor staging system. CONCLUSION: There might be the necessity of discriminating localized disease (IIE1) and locally advanced lesion (IIE2) to predict the prognosis of GIL through Musshoff's staging system. Larger study will be needed to confirm the role of Musshoff's staging system.
Classification
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Disease-Free Survival
;
Hodgkin Disease
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Prognosis
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Retrospective Studies*
;
Survival Rate