1.CT and MR Findings of Persistent Hyperplastic Primary Vitreous(PH PV).
Byung Gil CHOI ; Hong Jun CHUNG ; Ok Hwa KIM ; Bo Young AHN ; Sung Kun CHUNG
Journal of the Korean Radiological Society 1994;30(6):1141-1146
PURPOSE: The purpose of this paper is to discuss the characteristic CT and MR findings in persistent hyperplastic primary vitreous(PHPV) and to compare the detectability of those findings in each modality. MATERIALS AND METHODS: We retrospectively evaluated CT and MR findings in 32 patients with PHPV. Twenty-five patients had CT, 13 patients had MR, and 6 patients had both CT and MR. RESULTS: Major findings of PHPV in 32 patients on both imaging modalities were lens deformity(78%), shallow anterior chamber(72%), heterogeneous vitreous opacity(72%), enhancing hyaloid artery or remnant of fibrotic hand(69%), and microophthalmos(67%). Minor findings were retinal detachment(22%), and vitreous hemorrhage(6%). In MRI, lens deformity(92%) and shallow anterior chamber(85%) were detected most commonly whereas in CT, opaque vitreous(80%) was the most common finding. Findings of enhancing hyaloid vessel or remnant of fibrotic band, considered characteristic of PHPV, were more commonly detectable in MR (85%) than CT(52%). CONCLUSION: Characteristic MR and CT findings of PHPV were lena deformity, shallow anterior chanber, heterogeneons vitreons opacity, enhanciny hgalind artery or remnant fibrotic band, and microphthalmos. MR seemed to be more useful than CT in detecting Globe pathology.
Arteries
;
Congenital Abnormalities
;
Humans
;
Magnetic Resonance Imaging
;
Microphthalmos
;
Pathology
;
Retinaldehyde
;
Retrospective Studies
2.An Outbreak of Gastroenteritis Caused by Norovirus-Contaminated Groundwater at a Waterpark in Korea.
Seong Joon KOH ; Han Gil CHO ; Bo Hyun KIM ; Bo Youl CHOI
Journal of Korean Medical Science 2011;26(1):28-32
In January 2008, an outbreak of acute gastroenteritis at a waterpark was reported to the Bundang-gu Public Health Center in Seongnam, Korea. To determine the etiological agent and mode of transmission, a retrospective cohort study was done using structured questionnaires and stool samples from patients who had current gastrointestinal symptoms and three food handlers were tested. A total of 67 (31.0%) students and teachers developed acute gastroenteritis. No food items were associated with an increased risk of the illness. Norovirus was detected in 3 stool specimens collected from 6 patients who had severe diarrhea using semi-nested RT-PCR. All the specimens contained the genogroup I strains of the norovirus. Norovirus was also detected in the groundwater samples from the waterpark. In the nucleotide sequencing analysis, all the genogroup I noroviruses from the patients and groundwater samples were identified as the norovirus genotype I-4 strain. They were indistinguishable by DNA sequencing with a 97% homology. We conclude the outbreak of acute gastroenteritis caused by the norovirus was closely related to the contaminated groundwater.
Adult
;
Caliciviridae Infections/*epidemiology/*virology
;
Child
;
Cohort Studies
;
*Disease Outbreaks
;
Feces/virology
;
Female
;
Fresh Water/*virology
;
Gastroenteritis/*epidemiology/*virology
;
Genotype
;
Humans
;
Male
;
Norovirus/classification/genetics/*isolation & purification
;
Phylogeny
;
Republic of Korea
;
Retrospective Studies
;
Reverse Transcriptase Polymerase Chain Reaction
;
Sequence Analysis, RNA
3.An Outbreak of Gastroenteritis Caused by Norovirus-Contaminated Groundwater at a Waterpark in Korea.
Seong Joon KOH ; Han Gil CHO ; Bo Hyun KIM ; Bo Youl CHOI
Journal of Korean Medical Science 2011;26(1):28-32
In January 2008, an outbreak of acute gastroenteritis at a waterpark was reported to the Bundang-gu Public Health Center in Seongnam, Korea. To determine the etiological agent and mode of transmission, a retrospective cohort study was done using structured questionnaires and stool samples from patients who had current gastrointestinal symptoms and three food handlers were tested. A total of 67 (31.0%) students and teachers developed acute gastroenteritis. No food items were associated with an increased risk of the illness. Norovirus was detected in 3 stool specimens collected from 6 patients who had severe diarrhea using semi-nested RT-PCR. All the specimens contained the genogroup I strains of the norovirus. Norovirus was also detected in the groundwater samples from the waterpark. In the nucleotide sequencing analysis, all the genogroup I noroviruses from the patients and groundwater samples were identified as the norovirus genotype I-4 strain. They were indistinguishable by DNA sequencing with a 97% homology. We conclude the outbreak of acute gastroenteritis caused by the norovirus was closely related to the contaminated groundwater.
Adult
;
Caliciviridae Infections/*epidemiology/*virology
;
Child
;
Cohort Studies
;
*Disease Outbreaks
;
Feces/virology
;
Female
;
Fresh Water/*virology
;
Gastroenteritis/*epidemiology/*virology
;
Genotype
;
Humans
;
Male
;
Norovirus/classification/genetics/*isolation & purification
;
Phylogeny
;
Republic of Korea
;
Retrospective Studies
;
Reverse Transcriptase Polymerase Chain Reaction
;
Sequence Analysis, RNA
4.A Case of Ovarian Fibrosarcoma.
Hyun Jung KWON ; Ook Jin CHOO ; Bo Young BANG ; Kwang Yeob CHOI ; Yu Duk CHOI
Korean Journal of Obstetrics and Gynecology 1997;40(5):1097-1101
Fibromatous tumors of the ovary are considered to originate from specialized ovarianstromal cells and account for approximately 4% of all ovarian neoplasms. Most ovarianfibromatous tumors are benign, but infrequently there are histologically malignant appearances.Malignant fibromatous tumor can be categorized into two separate types of tumorsrelating to prognosis, cellular fibroma and fibrosarcoma. The cellular fibroma has one tothree mitotic counts per 10 high power fields(HPF). Unless an adhesion or rupture appearson this tumor, recurrence should not happen after operation. Furthermore, where themitotic count per 10 HPF is over four, it is classified as a very bad fibrosarcoma case interms of prognosis.We have met a case of large ovarian fibrosarcoma with has ten mitotic counts per10 HPF. We hereby report this case with the brief review of literatures.
Female
;
Fibroma
;
Fibrosarcoma*
;
Ovarian Neoplasms
;
Ovary
;
Prognosis
;
Recurrence
;
Rupture
5.Hazard Levels of Cooking Fumes in Republic of Korea Schools
Iu-Jin LEE ; Sang-Gil LEE ; Bo-Hwa CHOI ; Hoe-Kyeong SEO ; Ji-Hyung CHOI
Safety and Health at Work 2022;13(2):227-234
Background:
and PurposeIn 2021, lung cancer in school food workers was first recognized as an occupational cancer. The classification of the carcinogenicity of cooking fumes by International Agency for Research on Cancer (IARC) was based on Chinese epidemiological data. This study aimed to determine the hazard levels of school cooking fumes in Korea.
Materials and Methods:
Based on public school cafeterias in one area, 25 locations were selected for the survey according to the number per school type, ventilation states, and environmental pre-assessments of cafeterias. Two inside cooking areas using a heat source and one outside cooking area were selected as control measurement points. Measurements of CO, CO2, polycyclic aromatic hydrocarbons (PAHs), and total volatile organic compounds (TVOCs), including benzene, formaldehyde, and particulate matter (PM10, PM2.5, PM1, respectively), were taken. The concentrations and patterns of each substance in the kitchens were compared with the outdoor air quality.ResultKnown carcinogens, such as the concentrations of PAHs, formaldehyde, TVOC (benzene), and particulate matter in school cooking fumes, were all detected at similar or slightly higher levels than those found outside. Additionally, substances were detected at relatively low concentrations compared to the Chinese cooking fumes reported in the literature. However, the short-term exposure to high concentrations of CO (or composite exposure with CO2) and PM2.5 in this study were shown.
Conclusion
The school cooking fumes in South Korea was a relatively less harmful than Chinese cooking fumes, however short-term, high exposure of toxic substances can cause a critical health effect.
6.Gestational Trophoblastic Neoplasia: Efficacy of Color Doppler Ultrasound.
Sun Wha SONG ; Won Hee JEE ; Bo Young CHOE ; Jae Young BYUN ; Byung Gil CHOI ; Kyung Sub SHINN
Journal of the Korean Radiological Society 1997;36(4):665-669
PURPOSE: To evaluate the efficacy of color Doppler ultrasound (US) in the diagnosis of gestational trophoblastic neoplasia (GTN). MATERIALS AND METHODS: Intralesional color flows and resistive index (RI) on color Doppler US were prospectively analyzed in 21 consecutive suspected GTN cases. RI of the intralesional artery was investigated on the basis of the presence or absence of mass and metastasis. Correlation between RI of intralesional artery and urinary beta-hCG was also investigated. RESULTS: Intralesional color flows were identified in 15 patients with GTN. On operation, intralesional color flows were observed in one of two patients in whom the presence of completely necrotic tissue was confirmed. Intralesional color flows, however, were not detected in four patients who were proved not to be GTN sufferers. Sensitivity, specificity, accuracy, positive and negative predictive values, and accuracy were 100%, 83%, 95%, 94% and 100%, respectively. Significant correlation between RI of the intralesional artery and urinary beta-hCG was not established(p=0.49, r=0.19). RI of this artery was not substantially different between groups with and without mass, and between groups with and without metastasis(p=0.32, p=0.82). CONCLUSION: The current study demonstrates that color Doppler US is a sensitive and useful method for the diagnosis of GTN.
Arteries
;
Diagnosis
;
Gestational Trophoblastic Disease*
;
Humans
;
Neoplasm Metastasis
;
Prospective Studies
;
Sensitivity and Specificity
;
Ultrasonography*
7.Evaluation of Glioma with Thallium-201 Brain SPECT : The Correlation with 1H MR Spectroscopy and Pathology.
Hyung Sun SON ; Eui Nyung KIM ; Sung Hoon KIM ; Yee Ryung YOO ; Yong An JUNG ; Soo Gyo JUNG ; Yong Gil HONG ; Yeon Soo LEE ; Bo Young CHOI
Korean Journal of Nuclear Medicine 2000;34(6):465-477
PURPOSE: Thallim-201 (201Tl) brain SPECT and proton (1H) magnetic resonance spectroscopy (MRS) have been used to evaluate tumor grade and viability of glioma. We assessed the correlations between 201Tl brain index or spectrum of metabolites of 1H MRS and grade of glioma or histopathologic findings. MATERIALS AND METHODS: We studied 17 patients (4 astrocytoma, 7 anaplastic astrocytoma and 6 glioblastoma). On 201Tl Brain SPECT, 201Tl index was measured as the ratio of average counts for region of interest to those for the contralateral normal brain. On 1H MRS, we calculated choline (Cho) /creatine (Cr) ratio and N-acetylaspartate (NAA)/Cr ratio in ROI defined as tumor center. Histopathologic findings were graded by Ki-67 index, cellularity, mitosis, pleomorphism, necrosis and endothelial proliferation. An unpaired t test and statistical correlations were performed to evaluate these data. RESULTS: Tl-index showed the best correlation with Ki-67 index (p<0.01), less correlations with cellularity, mitosis, and endothelial proliferation, but no correlation with results of MRS, pleomorphism, or necrosis. The findings of MRS did not correlate with all of the above. The cases of glioblastoma demonstrated a higher Tl-index, Cho/Cr ratio, Ki-67 index and lower NAA/Cr ratio, albeit without statistical significance. CONCLUSION: Even though 201Tl brain SPECT did not correlate directly with grade of malignancy, it may still be useful in determining biological aggressiveness of tumor and prognosis of patients because it correlated well with Ki-67 index, a growth fraction of glioma, cellularity, mitosis and endothelial proliferation.
Astrocytoma
;
Brain*
;
Choline
;
Glioblastoma
;
Glioma*
;
Humans
;
Magnetic Resonance Spectroscopy*
;
Mitosis
;
Necrosis
;
Pathology*
;
Prognosis
;
Protons
;
Tomography, Emission-Computed, Single-Photon*
8.The Comparative Study of Microsurgical Cerebral Aneurysm Clip Implants; Titanium Clip vs. Stainless Steel Clip.
Sung Ho CHOI ; Cheol Wan PARK ; Young Bo KIM ; Eun Young KIM ; Chang Jong YOU ; Woo Kyung KIM
Journal of Cerebrovascular and Endovascular Neurosurgery 2012;14(2):79-83
OBJECTIVE: To perform a comparative study between two groups of populations, titanium (T) group versus stainless steel (S) group, who were clipped with titanium and stainless steel materials, respectively, the incidence of regrowth from the original aneurysms, the clip slippage, and post-clipping seizure attack were analyzed. The patients were followed more than 5 years after microsurgical cerebral aneurysms clipping. METHODS: Data from 1986 through 2008 were extensively reviewed on a consecutive series of 3,770 patients who referred for ruptured/unruptured cerebral aneurysms. Forty-seven patients in the S group and 48 in the T group who met inclusion criteria, were selected for this study. RESULTS: The incidence of regrowth were noted that two out of total 47 patients (4.3%) in the S group, and none in the T group. The clip slippage was not observed in both groups. And there was no statistical difference (p = 0.242) in terms of regrowth between two groups. Seven out of 47 cases (14.9%) developed post-clipping seizure in the S group. On the other hand, two (4.2%) of 48 patients presented the symptom in the T group. Also, there was no significant difference (p = 0.091) between two groups. CONCLUSIONS: The metallic types of clip employed for the microsurgical cerebral aneurysm clipping does not have any significant clinical outcome differences in this study.
Aneurysm
;
Hand
;
Humans
;
Incidence
;
Intracranial Aneurysm
;
Seizures
;
Stainless Steel
;
Titanium
9.Metabolic Changes in Pericontusional Edematous Areas in Mild Head Injury Evaluated by Proton MRS.
Sang Su HONG ; Byung Chul SON ; Byung Gil CHOI ; Euy Nyeng KIM ; Bum Soo KIM ; Chun Kum PARK ; Bo Young CHOE ; Moon Chan KIM ; Joon Ki KANG
Journal of Korean Neurosurgical Society 2000;29(9):1233-1237
No abstract available.
Craniocerebral Trauma*
;
Head*
;
Protons*
10.CT and MR Imaging Findings of Cystic Adenomyosis of the Uterus: Report of Three Cases.
Sung Eun KIM ; Byung Gil CHOI ; Jee Hee BAEK ; Jae Young BYUN ; Bo Hyun KIM
Journal of the Korean Radiological Society 2000;42(6):971-974
Adenomyosis of the uterus is a relatively common gynecologic disease characterized by the presence of ectopic endometrial glands and stroma within the myometrium. Small cystic spaces (not larger than several mil-limeters) are invariably present, and these are filled with blood. Extensive hemorrhagic cystic adenomyosis,however, is rare, and there have been very few radiologic reports of this condition. We describe the CT and MRI features of three cases of histologically confirmed huge cystic adenomyosis.
Adenomyosis*
;
Animals
;
Female
;
Genital Diseases, Female
;
Magnetic Resonance Imaging*
;
Mice
;
Myometrium
;
Uterus*