1.Discussion on the dispersion & agglomeration of aircraft industry
Journal of Pharmaceutical Analysis 2009;21(3):192-197,208
The aircraft industry is crucial to the economy and security of a nation. In this paper, the spatial characteristics and patterns of the aircraft industry are analyzed on different spatial scales. It is found that there is a 'Matthew effect' in the global aircraft industry and the spatial evolution of the industry is consistent with the industrialization process of the whole country. It is also revealed that the spatial evolution of the country is driven by both the centripetal forces including capital, talents, technology and agglomeration economies and the centrifugal forces including the comparative advantage, cost &risk sharing, emerging markets, development policy for less-developed regions and the military imperative. These forces have both market-stabilizing and market-disrupting effects on the spatial evolution of the aircraft industry. The study suggests that lessons drawn from the experiences in the United States and France are expected to be conducive to the rise of China's aircraft industry in the future.
2.Surgical resection for the diagnosis and treatment of primary pulmonary mucosa-associated lymphoid tissue lymphoma
Bin WANG ; Bo WANG ; Xiangyang CHU ; Lianbin ZHANG
Chinese Journal of Clinical Oncology 2013;(19):1192-1195
Objective:To discuss the clinical and imaging features as well as the treatment and prognosis of primary pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma. Methods:We retrospectively analyzed the clinical, imaging, and follow-up data of 13 patients with pulmonary MALT lymphoma in the Chinese PLA General Hospital from April 2000 to July 2012. Results:Of the 13 patients with pulmonary MALT lymphoma, 8 were male and 5 were female (1.6:1 ratio). The age of onset varies from 21 years to 67 years, and the median age is 59 years. The major clinical manifestations include chest discomfort in 6 cases, cough in 2 cases, fever in 2 cases, and chest pain in 1 case. Two cases had no observable discomfort. One patient suffered from Sj?gren's syndrome. The chest CT of the patients showed pulmonary consolidation with air bronchogram in 3 cases, patchy shadows in 3 cases, mass shadow in 4 cases, and ground-glass opacities in 4 cases. In addition, 10 cases showed bilateral pulmonary multiple changes, 4 showed mediastinal lymph node enlargement, and 1 showed pleural effusion. Operation was performed on 6 patients, 3 of which were given postoperative adjuvant chemotherapy. Four patients underwent chemotherapy involving the CHOP or R-CHOP regimen, whereas three patients received symptomatic and supportive treatment only. One case was lost to follow-up. The follow-up period ranged from 1 year to 11 years. In one patient, the disease progressed four years after the diagnosis, and the patient died after 11 years. One patient died from the side effects of chemotherapy. The remaining 10 cases were still alive and did not show any progression of the disease. Conclusion:The clinical feature of pulmonary MALT lymphoma is not typical. Thus, imaging techniques cannot detect specific changes. Surgical resection is vital in the diagnosis and treatment of this disease because it can help provide a clear diagnosis, particularly to patients with limited lesions and from which specimens could not be obtained using conventional methods. Moreover, the prognosis of this treatment is generally good.
3.Numerical simulation of treating aortic dissection using artery-abdominal aorta bypass graft
Yun ZHANG ; Bo CHU ; Jianchun GUAN ; Aike QIAO
Chinese Journal of Tissue Engineering Research 2009;13(52):10325-10329
Aortic dissection is a common disease which is very dangerous,with high mortality rate.Bypass graft for the treatment of DeBakey Ⅲ dissection has outstanding advantages than the ordinary replacement of thoracic aorta,and some patients will inevitably require the use of the procedure.The purpose of this study was to explore the impact of the subclavian artery-abdominal aorta bypass graft on hemodynamic parameters in the false lumen and the effectiveness of surgical treatment.First of all,the idealized three-dimensional geometric models of DeBakey Ⅲ aortic dissection and its subclavian artery-abdominal aorta bypass graft operation were constructed,respectively.Then the models were imported into ANSYS 11.0 for finite element analysis.Results of numerical simulation showed that both velocity and pressure of the blood flow were reduced after bypass graft at the entrance and in the internal sac of false lumen,which is very favorable for reducing the impact of blood flow on false lumen,slowing down the further expansion of entrance,preventing the breakdown of false lumen,and promoting the healing of dissection.Therefore,the subclavian artery-abdominal aorta bypass graft operation is an effective surgical method for the treatment of DeBakey Ⅲ aortic dissection in some particular cases.This operation is with great prospects for clinical application.
4.A case of advanced ovarian cancer which was treated with topotecan after taxol-cisplatin treatment failed.
Hyun Soo CHOI ; Chu Yeop HUH ; Seung Bo KIM
Korean Journal of Obstetrics and Gynecology 2000;43(5):914-917
Ovarian cancer has the highest mortality rate among gynecologic malignancies in developed countries. Most women present with advanced disease and require a combination of surgery and chemotherapy. One patient presented with recurrent ovarian cancer was initially treated with taxol and platinum-based compounds. Although response to these agents occurred, tumor progression was evident by elevated CA 125 levels and CT findings after a period of 4 months. This patient was then treated with topotecan and exhibited a response and stopped therapy. Topotecan exhibited activity in this patient with ovarian cancer resistent to both platinum and paclitaxel. We report a case of advanced ovarian cancer which was treated with topotecan after taxol-cisplatin treatment failed.
Developed Countries
;
Drug Therapy
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Female
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Humans
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Mortality
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Ovarian Neoplasms*
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Paclitaxel
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Platinum
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Topotecan*
5.A case of primary carcinoma of the fallopian tube.
Young Ki LEE ; Chu Yeop HUH ; Seung Bo KIM
Korean Journal of Obstetrics and Gynecology 1993;36(11):3814-3819
No abstract available.
Fallopian Tubes*
;
Female
6.A case of endodermal sinus tumor of the ovary treating with BEP regimen.
Mi Young KIM ; Chu Yeop HUR ; Seong Bo KIM
Korean Journal of Obstetrics and Gynecology 1993;36(8):3358-3365
No abstract available.
Endoderm*
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Endodermal Sinus Tumor*
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Female
;
Ovary*
9.Pulsed radio-frequency stimulation combined with nerve block for cervicogenic headache
Bo LI ; Hui CHU ; Hong HUANG ; Hang YU ; Zhijiu XU
Chinese Journal of Physical Medicine and Rehabilitation 2012;(11):837-840
Objective To observe the clinical effect on cervicogenic headache (CEH) of pulsed radiofrequency stimulation (PRF) applied to the C2 dorsal root ganglion combined with nerve block.Methods A total of 78 cases diagnosed as CEH were randomly divided into a combined treatment group,a PRF treatment group and a nerve block group.The combined treatment group was given both PRF applied to the C2 dorsal root ganglion and blocking therapy.The other two groups were given only one treatment or the other.All the treatments were once weekly for 3 weeks.Before treatment and 1,3 and 6 months after treatment,all of the patients' headaches were evaluated using a visual analogue scale (VAS).Results At 1,3 and 6 months after treatment,the average VAS scores of all three groups had decreased significantly.The VAS ratings dropped the most in the combined treatment group,followed by the PRF group and then the nerve block group.All the intergroup differences were statistically significant.The combined treatment group's cure rate (88%) was significantly better than that of the PRF group (81%),which was significantly better than that of the nerve block group (54%).Conclusion Combining PRF applied to the C2dorsal root ganglion with nerve block therapy has a synergistic effect on CEH.The curative effect of the combined treatment was better than either PRF or blocking alone.
10.Optimizing the establishment of endometriosis model in rats by orthogonal experiment
Bo CHU ; Tao JIANG ; Chunping TANG ; Chaoyan YANG ; Mengjuan GONG
Chinese Pharmacological Bulletin 2003;0(07):-
Aim To probe into the best conditions for the establishment of endometriosis model in rats by the orthogonal experiment method.Methods Autotransplantation was used to establish the endometriosis model in rats by the orthogonal experiment method in which four main factors were considered to optimize the condition of model,according to the volume of heterotopic endometrium.Results The para ligament of uterus was the best place for transplanting.Both dissecting muscular layer and injecting estrin played an important role in the establishment of endometriosis model in rats. The value of four factors decreased progressively according to the injection of estrin,the dissection of muscular layer,the direction of endometrium implantation and oestrus.Conclusions By optimizing the condition for the establishment of endometriosis model in rats by orthogonal experiment,the volume of heterotopic endometrium was improved.A technology platform for pharmacodynamics research was thus offered.