No abstract available.
Blood Group Incompatibility* ; Humans

No abstract available.
Blood Group Incompatibility*

No abstract available.
Blood Group Incompatibility* ; Bromelains*

No abstract available.
Blood Group Incompatibility

Cis A2B3 is a rare blood type with unusual inheritance pattern of A2, B3 genes on the same chromosome in contradiction to the general Mendelian pattern. Unlike the AB blood type, cis A2B3 shows weaker B antigenicity and unexpectedly has moderate amount of anti-B antibody in serum. Thus it has the potential of misidentification as blood type A or AB and the possibility of acute major transfusion reaction from transfusion of the usually known AB blood group RBCs. This is a case report of anesthetic management of one patient with his blood type discovered as cis A2B3 preoperatively. During hip surgery he received 2 units of washed O RBCs without any problems. I report the anesthetic experience with a brief review of literature.
Blood Group Incompatibility ; Hip ; Humans ; Inheritance Patterns

BACGROUND: Recently, transfusion by component blood products instead of whole blood has gradually increased. And also filtered and/or irradiated blood products for the prevention of GVHD and other transfusion reaction has been used. To probe trends of recent transfusion, we analysed the use of blood components from 1989 through 1996 in Chonnam University Hospital. METHODS: We reviewed blood bank records from 1989 through 1996 in Chonnam University Hospital. RESULTS: 1. Total numbers of transfused blood units from 1989 to 1996 were 369,326 and the rate of component transfusion increased from 24.5% (1989) to 99.6% (1996) in Chonnam University Hospital. 2. Total numbers of transfused whole bloods were 5,569 units (24.5%) in 1989, then declined to 327 units (0.5%) in 1996. 3. Transfusion of PRC increased from 9,325 units (41.1%) in 1989 to 24,368 units (35.8%) in 1996, and also FFP from 7,371 units (32.4%) in 1989 to 15,546 units (22.9%) in 1996. 4. Use of platelet concentrates increased 16.4-fold from 2,223 units (2.5%) in 1989 to 36,531 units (46.8%) in 1996. 5. In 1996, percentage of filtered and irradiated blood products was 32.3% from cellular blood products. 6. With the use of the advanced blood seperator, hemapheresis showed slight increase annually. CONCLUSION: This paper will provide the basis of blood supply in Chonnam University Hospital and blood center.
Blood Banks ; Blood Group Incompatibility ; Blood Platelets ; Jeollanam-do*

BACKGROUND: Performing antibody screening and identification tests before blood transfusion are important since unexpected red cell antibodies can cause acute or delayed hemolytic transfusion reactions. We investigated the frequency and distribution of unexpected red cell antibodies that were detected in cancer patients at National Cancer Center (NCC) and we compared our results with the previously published data. METHODS: From January 2001 to June 2009, 56,660 sera of the cases from NCC were screened and 197 sera were identified with using the Ortho BioVue System (Ortho-Clinical Diagnostics, Raritan, USA) and the conventional tube method. In case of the presence of autoantibody, the ZZAP method was performed to distinguish alloantibody from autoantibody. RESULTS: 759 cases (1.34%) showed positive results out of all 56,660 cases that underwent unexpected antibodies screening. Among them, unexpected antibodies were identified in 197 cases. The most frequently detected antibody was anti-Le(a) in 62 cases (31.47%), followed by anti-E in 32 cases (16.24%) and anti-Le(b) in 18 cases (9.14%). Unidentified antibodies were detected in 43 cases (21.83%). In the cases with a previous history of transfusion at the NCC and the screening results were altered from negative to positive, anti-E was the most frequently detected antibody (8/30 cases, 26.67%), and this included the mixed antibodies. CONCLUSION: Compared with the previous reports, this study showed that the frequency and distribution of the unexpected red cell antibodies of cancer patients were not different from those of general patients. Moreover, there was no apparent difference of frequency of the unexpected red cell antibodies among the diagnosed cancers. Our research may provide data for the frequency and characteristics of red cell antibodies because we targeted only cancer patients.
Antibodies ; Blood Group Incompatibility ; Blood Transfusion ; Humans ; Mass Screening

Transfusion can cause transfusion-transmitted diseases and various transfusion reactions. Recent improvements in the safety of blood supply and the increasing costs associated with transfusion therapies have led to a re-evaluation of the clinical practices of blood transfusion and blood conservation, which need practical guidelines for the use of constituent parts of blood. The traditional threshold of the hemoglobin concentration at 10g /dL for RBC transfusion has moved down to 7g /dL, and that of the platelet count at 20 x 10(9)/L for platelet transfusion can also be lowered to 5 x 10(9)/L. To improve the transfusion practice, as recommended by the guidelines, a prospective audit allied to educational programs can be effective in modifying the clinicians' practices of requesting transfusions.
Blood Group Incompatibility ; Blood Transfusion ; Platelet Count ; Platelet Transfusion

BACKGROUND: Antibody screening and identification tests are indispensable tools for protecting patients from acute hemolytic transfusion reaction. The column agglutination method has been widely used because of its simplicity and superiority to other methods for detecting warm antibodies. The purpose of this study was to analyze the frequency, distribution and clinical characteristics of unexpected antibodies found in transfusion candidates at a secondary hospital in Gyeongbuk Province, Korea. METHODS: The antibody screening tests were carried out with 9,275 sera samples using the column agglutination method from July 2009 to September 2011. The antibodies were screened and identified using the DiaMed-ID system (DiaMed, Murten, Switzerland). RESULTS: The positive rate for antibody screening tests was 0.5% (50/9,275). Unexpected antibodies were identified in 36 cases (0.4%). The most frequently detected antibody was anti-Lea in 15 cases (30%), followed by anti-Leb in 10 cases (20%) and anti-E in 8 cases (16%). Antibodies that remain unidentified were detected in 11 cases (22%). CONCLUSION: Compared with previous reports, this study demonstrated that the frequency and distribution of unexpected antibodies were no different than those found in general hospitals. This study may provide data for the frequency and characteristics of unexpected antibodies in a secondary hospital.
Agglutination ; Antibodies ; Blood Group Incompatibility ; Hospitals, General ; Humans ; Mass Screening

BACKGROUND: The Korean Red Cross(KRC) are considering the introduction of prestorage leukoreduced RBCs, as it is thought one of best way to prevent WBC-associated adverse transfusion reactions. We evaluated two different quadruple top-and-bottom collection bags, specially designed for this purpose by two manufacturers(Boin Medica Co.,Ltd and Green Cross Medical Corporation, Korea), consisted of a CPD bag, a SAG-M bag and an inline RBC filter, either RCM1 (Pall Medical, U.S.A.) or BioR 01 1N (Fresenius Hemocare, Germany) each. METHODS: Fifty one bags from Boin and sixty bags from Green Cross and consequent blood components were studied in twice over a period of two years. As an inline filter, Boin used RCM1 and Green Cross used RCM1(1st) and BioR 01 1N(2nd). They were divided into group A(filtration performed after processing of RBCs) and B(filtration performed after storage of overnight at 4 degrees C). WBC-reduced RBCs were tested for pH, plasma K+, plasma Hb and blood culture every 7 days to investigate storage time-dependent changes up to 42 days. RESULTS: The results of pH, plasma K+ and plasma Hb from CPD added whole blood, RBCs, SAG-M added RBCs and WBC-reduced RBCs did not show significant differences. We observed both of adding SAG-M solution and filtration procedure did not effect on the prestorage leukoreduced RBCs. WBCs were removed effectively by prestorage filtration. But in the case of failed units, the design or method to integrate an RBC filter may be a cause for the failure. CONCLUSION: We concluded that two different quadruple collection bags with integral RCM1 filter from Boin(2nd) and Green Cross(1st) are useful for production of prestorage leukoreduced RBCs.
Blood Group Incompatibility ; Filtration ; Hydrogen-Ion Concentration ; Plasma