The habituation of early (R1) and late response (R2) of blink reflex was investigated in 44 patients with Parkinson's disease (PD) and 19 control subjects. The latency, duration and area of R1 and R2 components of blink reflex in single stimulation, and the percentage recovery of R1 in paired stimulation were not different between patients and control subjects. However, in PD patients, the latency of R2 evoked by test stimuli was shorter than that of conditioning stimuli, and the percentage recovery of R2 habituation was increased as compared to that of control subjects. The degree of early recovery of R2 habituation was slightly more evident in advanced PD patients and nonmedicated patients than that of control subjects. In addition, the early recovery of R2 was present in the test of asymptomatic side of PD patients. Our results suggests that blink reflex may be used as a method of evaluating the clinical status of PD patients.
Blinking* ; Humans ; Parkinson Disease*

Independent Component Analysis (ICA) is a signal processing algorithm to separate independent sources from unknown mixed signals and can be applied to separate artifacts and independent neural sources from EEG recordings. This study was designed to extract individual components of eyeball movements from scalp EEG. Digital EEG signals were recorded using the international 10-20 system during eye closure, eye opening, and blinking. 18 EEG tracings using bipolar montage were analyzed by ICA algorithm into 18 independent components. Each of the components was reviewed, selected, and reconstructed into an original montage. Among 18 components, two components which were thought to represent eyeball movements were obtained. Each of the components was inversely projected into the original bipolar montage. This inverse projection showed separated vertical and horizontal eyeball movements components. These results suggest that the ICA analysis of EEG can separate vertical and horizontal eyeball movements and may be applied to separate other EEG artifacts and source signals from unknown mixed sources recordings of EEG.
Artifacts ; Blinking ; Electroencephalography ; Scalp

No abstract available.
Blinking ; Meningioma* ; Trigeminal Neuralgia*

PURPOSE: As the evaluation of the preoperative sensibility in the orbitozygomatic complex fracture, used by most surgeons, depends on the patient's subjective judgements, it is difficult to make generalization and to use it as an objective evaluation method. We used the blink reflex study to objectively evaluate injury to the infraorbital nerve. METHODS: From December 2008 to November 2009, a total of 16 patients underwent the patient's subjective report on sensory symptoms and the blink reflex study preoperatively. Among patients having orbitozygomatic complex fracture of type III or more according to Henderson's classification and simultaneously suspected as being injured along the infraorbital nerve pathway, patients who had difficulty in checking preoperative sensibility and said 'normal sensibility' were selected as candidates. RESULTS: Fifteen patients showed abnormal R1 on the fracture side. These results suggested that most of patients had injury to the infraorbital nerve. CONCLUSION: Contrary to the existing tests, the blink reflex study is a useful diagnostic tool in reflecting injury to the infraorbital nerve objectively.
Blinking ; Generalization (Psychology) ; Humans

No abstract available.
Blinking ; Infarction ; Trigeminal Nerve Diseases

No abstract available.
Blinking* ; Facial Nerve* ; Hemifacial Spasm*

No abstract available.
Blinking* ; Cerebellopontine Angle* ; Neuroma, Acoustic*

No abstract available.
Blinking* ; Cerebellopontine Angle* ; Neuroma, Acoustic*

No abstract available.
Blinking* ; Diplopia ; Miller Fisher Syndrome*

PURPOSE: To evaluate the changes of higher order aberration according to tear-film instability measured serially by KR-1W wavefront every second for 10 seconds. The present study also analyzed the relationship between higher order aberration and the tear-film break-up time, Schirmer test, and superficial punctate keratitis. METHODS: The 228 eyes of 114 patients randomly selected from patients who visited hospital were measured once every second for 10 seconds after eye blinking by continuous measurement using wavefront. RESULTS: Higher order aberration increased overtime, and the higher order aberration value measured at the tenth second subtracted from the value of the first second was statistically significant (p = 0.004). In addition, the increment in higher order aberration between 9 seconds and 10 seconds was statistically significant (p = 0.01). The group of patients with a tear-film break-up time less than 6 seconds showed the greatest changes when measuring the higher order aberration difference value between the tenth and first seconds, which was statistically significant (p = 0.002). The group of patients where the Schirmer test results were longer than 10 millimeters and who had superficial punctate keratitis showed the greatest statistically significant changes when measuring the difference in higher order aberration values between the tenth and first seconds (p = 0.008, p = 0.005, respectively). CONCLUSIONS: Analysis of higher order aberration by wavefront could be useful in cases of decreased optical quality, diagnosis and evaluation of treatment in dry eye syndrome.
Blinking ; Dry Eye Syndromes ; Eye ; Humans ; Keratitis